Vault-13

SUTRO BIOPHARMA INC

COM · CUSIP 869367102

102 institutional holders -12 vs Q1 2025
55,778,07055.8m shares reported held*
$39.8mreported value*
30 new 23 added 24 reduced 42 sold out net sold ≈ $4.1m (-5.7m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Implied quarter-end price ≈ $0.71. Options: 4 managers hold calls ($40.6k notional), 1 hold puts ($0).

Trends to Q2 2025

Institutional holders

Managers reporting a position, each quarter

050100150Q3 22: 113Q4 22: 120Q1 23: 117Q2 23: 121Q3 23: 110Q4 23: 115Q1 24: 118Q2 24: 120Q3 24: 131Q4 24: 124Q1 25: 114Q2 25: 102102Q3 22Q2 23Q1 24Q4 24Q2 25
Numbers
QuarterHolders
Q3 2022113
Q4 2022120
Q1 2023117
Q2 2023121
Q3 2023110
Q4 2023115
Q1 2024118
Q2 2024120
Q3 2024131
Q4 2024124
Q1 2025114
Q2 2025102

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
1000100Q3 23: 51 bought or addedQ3 23: 50 cut or sold outQ4 23: 62 bought or addedQ4 23: 44 cut or sold outQ4 23Q1 24: 69 bought or addedQ1 24: 49 cut or sold outQ2 24: 77 bought or addedQ2 24: 47 cut or sold outQ2 24Q3 24: 71 bought or addedQ3 24: 42 cut or sold outQ4 24: 55 bought or addedQ4 24: 66 cut or sold outQ4 24Q1 25: 54 bought or addedQ1 25: 58 cut or sold outQ2 25: 53 bought or addedQ2 25: 66 cut or sold outQ2 25
Numbers
QuarterBought or addedCut or sold out
Q3 20235150
Q4 20236244
Q1 20246949
Q2 20247747
Q3 20247142
Q4 20245566
Q1 20255458
Q2 20255366

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$100k$200k$300kQ3 24 calls: $267.8kQ3 24 puts: $120.8kQ3 24P/C 0.45Q4 24 calls: $243.1kQ4 24 puts: $66.8kQ4 24P/C 0.27Q1 25 calls: $34.5kQ1 25 puts: $27.0kQ1 25P/C 0.78Q2 25 calls: $40.6kQ2 25 puts: $0Q2 25P/C 0.00
Numbers
QuarterCallsPutsP/C
Q3 2024$267.8k$120.8k0.45
Q4 2024$243.1k$66.8k0.27
Q1 2025$34.5k$27.0k0.78
Q2 2025$40.6k$00.00

Biggest buyers

MILLENNIUM MANAGEMENT LLC Added +4,029,088+4.0m
TANG CAPITAL MANAGEMENT LLC Added +2,361,586+2.4m
Velan Capital Investment Management LP Added +2,030,000+2.0m
UBS Group AG Added +1,543,313+1.5m
JANE STREET GROUP, LLC New +688,850+688.9k
CANTOR FITZGERALD, L. P. New +500,000+500.0k
ROYAL BANK OF CANADA Added +437,461+437.5k
MARSHALL WACE, LLP New +234,431+234.4k
RBF Capital, LLC New +160,000+160.0k
SUSQUEHANNA INTERNATIONAL GROUP, LLP Added +142,864+142.9k

Biggest sellers

RA CAPITAL MANAGEMENT, L.P. Sold out -4,434,637-4.4m
BlackRock, Inc. Reduced -4,097,776-4.1m
STATE STREET CORP Reduced -1,339,687-1.3m
GOLDMAN SACHS GROUP INC Reduced -1,306,367-1.3m
GEODE CAPITAL MANAGEMENT, LLC Reduced -1,072,357-1.1m
MONTANOVA CAPITAL, LLC Reduced -974,171-974.2k
PRUDENTIAL FINANCIAL INC Reduced -569,080-569.1k
NORTHERN TRUST CORP Reduced -466,189-466.2k
Kynam Capital Management, LP Reduced -353,348-353.3k
AQR CAPITAL MANAGEMENT LLC Reduced -308,201-308.2k

Biggest calls

SIMPLEX TRADING, LLC Added $25.0k36.2k shares
CITADEL ADVISORS LLC Added $12.7k17.8k shares
GROUP ONE TRADING LLC New $2.9k4.1k shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares

Biggest puts

CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
Affinity Asset Advisors, LLC 13G · passive investor new · filed 2025-10-23 7.8% new 6.6m 2025-10-23
MILLENNIUM MANAGEMENT LLC 13G · passive investor new · filed 2025-06-30 5.6% new 4.7m 2025-06-30
Kynam Capital Management, LP 13G · institution -1.2 pts · filed 2026-05-15 5.3% -1.2 pts 0 2026-05-15

Fell to 5% or below in the last year: SUVRETTA CAPITAL MANAGEMENT, LLC (0.0%, 2026-02-13)

Holders, Q2 2025

#ManagerLocationShares Value% of their portfolioChangeShares change
1 MONTANOVA CAPITAL, LLC 0.17% of their portfolio New York, NY 6,488,3246.5m $4.6m $4.6m 0.17% Reduced -974.2k -974,171
2 Kynam Capital Management, LP 0.39% of their portfolio PRINCETON, NJ 5,088,0995.1m $3.6m $3.6m 0.39% Reduced -353.3k -353,348
3 MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio NEW YORK, NY 4,732,2434.7m $3.4m $3.4m 0.00% Added +4.0m +4,029,088
4 VANGUARD GROUP INC 0.00% of their portfolio Valley Forge, PA 4,115,2504.1m $2.9m $2.9m 0.00% Reduced -280.0k -279,994
5 Velan Capital Investment Management LP 2.19% of their portfolio ALPHARETTA, GA 3,060,0003.1m $2.2m $2.2m 2.19% Added +2.0m +2,030,000
6 ACADIAN ASSET MANAGEMENT LLC 0.00% of their portfolio Boston, MA 3,042,2383.0m $2.2m $2.2m 0.00% Reduced -92.3k -92,348
7 Merck & Co., Inc. 0.95% of their portfolio RAHWAY, NJ 2,723,5092.7m $1.9m $1.9m 0.95% Unchanged
8 Vestal Point Capital, LP 0.10% of their portfolio NEW YORK, NY 2,600,0002.6m $1.9m $1.9m 0.10% Unchanged
9 TANG CAPITAL MANAGEMENT LLC 0.09% of their portfolio SAN DIEGO, CA 2,561,5862.6m $1.8m $1.8m 0.09% Added +2.4m +2,361,586
10 Eversept Partners, LP 0.16% of their portfolio NEW YORK, NY 2,292,2612.3m $1.6m $1.6m 0.16% Unchanged
11 SAMSARA BIOCAPITAL, LLC 0.32% of their portfolio PALO ALTO, CA 2,196,8142.2m $1.6m $1.6m 0.32% Unchanged
12 BlackRock, Inc. 0.00% of their portfolio New York, NY 2,107,0082.1m $1.5m $1.5m 0.00% Reduced -4.1m -4,097,776
13 ADAGE CAPITAL PARTNERS GP, L.L.C. 0.00% of their portfolio Boston, MA 2,000,0002.0m $1.4m $1.4m 0.00% Unchanged
14 UBS Group AG 0.00% of their portfolio ZURICH, V8 1,618,8841.6m $1.2m $1.2m 0.00% Added +1.5m +1,543,313
15 AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio Greenwich, CT 1,012,7161.0m $723.0k $723.0k 0.00% Reduced -308.2k -308,201
16 RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio NEW YORK, NY 913,197913.2k $651.9k $651.9k 0.00% Added +44.2k +44,200
17 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 816,915816.9k $583.4k $583.4k 0.00% Reduced -1.1m -1,072,357
18 Affinity Asset Advisors, LLC 0.08% of their portfolio NEW YORK, NY 752,722752.7k $537.4k $537.4k 0.08% Unchanged
19 JANE STREET GROUP, LLC 0.00% of their portfolio NEW YORK, NY 688,850688.9k $491.8k $491.8k 0.00% New
20 DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio AUSTIN, TX 628,473628.5k $448.8k $448.8k 0.00% Reduced -189.0k -189,006
21 CANTOR FITZGERALD, L. P. 0.01% of their portfolio NEW YORK, NY 500,000500.0k $356.9k $356.9k 0.01% New
22 ROYAL BANK OF CANADA 0.00% of their portfolio TORONTO, A6 443,658443.7k $318.0k $318.0k 0.00% Added +437.5k +437,461
23 DAFNA Capital Management LLC 0.09% of their portfolio LOS ANGELES, CA 437,079437.1k $312.0k $312.0k 0.09% Unchanged
24 GOLDMAN SACHS GROUP INC 0.00% of their portfolio NEW YORK, NY 405,748405.7k $289.7k $289.7k 0.00% Reduced -1.3m -1,306,367
25 LPL Financial LLC 0.00% of their portfolio FORT MILL, SC 370,748370.7k $264.7k $264.7k 0.00% Reduced -19.2k -19,184
26 Fisher Asset Management, LLC 0.00% of their portfolio PLANO, TX 352,949352.9k $252.0k $252.0k 0.00% Unchanged
27 STATE STREET CORP 0.00% of their portfolio BOSTON, MA 342,652342.7k $244.6k $244.6k 0.00% Reduced -1.3m -1,339,687
28 Shay Capital LLC 0.04% of their portfolio NEW YORK, NY 259,889259.9k $185.5k $185.5k 0.04% Added +54.3k +54,269
29 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 258,595258.6k $184.6k $184.6k 0.00% Added +62.7k +62,735
30 SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio BALA CYNWYD, PA 245,206245.2k $175.1k $175.1k 0.00% Added +142.9k +142,864
31 MARSHALL WACE, LLP 0.00% of their portfolio LONDON, X0 234,431234.4k $166.4k $166.4k 0.00% New
32 AJU IB Investment Co., Ltd. 0.14% of their portfolio Seoul, M5 175,000175.0k $124.9k $124.9k 0.14% Unchanged
33 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 173,477173.5k $123.8k $123.8k 0.00% Reduced -127.9k -127,930
34 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 167,734167.7k $119.7k $119.7k 0.00% Reduced -466.2k -466,189
35 RBF Capital, LLC 0.01% of their portfolio RENO, NV 160,000160.0k $114.2k $114.2k 0.01% New
36 IEQ CAPITAL, LLC 0.00% of their portfolio Foster City, CA 123,319123.3k $88.0k $88.0k 0.00% Added +48.3k +48,253
37 Qube Research & Technologies Ltd 0.00% of their portfolio LONDON, X0 115,401115.4k $82.4k $82.4k 0.00% New
38 TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio NEW YORK, NY 115,068115.1k $82.1k $82.1k 0.00% Added +19.2k +19,187
39 Cerity Partners LLC 0.00% of their portfolio NEW YORK, NY 105,437105.4k $75.3k $75.3k 0.00% Added +66.4k +66,372
40 Invesco Ltd. 0.00% of their portfolio ATLANTA, GA 103,320103.3k $73.8k $73.8k 0.00% Added +11.2k +11,181
41 OMERS ADMINISTRATION Corp 0.00% of their portfolio TORONTO, A6 95,15095.2k $67.9k $67.9k 0.00% Unchanged
42 HRT FINANCIAL LP 0.00% of their portfolio NEW YORK, NY 85,50985.5k $61.0k $61.0k 0.00% Added +58.7k +58,731
43 Jain Global LLC 0.00% of their portfolio NEW YORK, NY 84,47284.5k $60.3k $60.3k 0.00% New
44 BANK OF AMERICA CORP /DE/ 0.00% of their portfolio CHARLOTTE, NC 78,94678.9k $56.3k $56.3k 0.00% Reduced -30.2k -30,155
45 Aberdeen Group plc 0.00% of their portfolio EDINBURGH, X0 69,38969.4k $49.5k $49.5k 0.00% Unchanged
46 Y-Intercept (Hong Kong) Ltd 0.00% of their portfolio HONG KONG, K3 66,59166.6k $47.5k $47.5k 0.00% New
47 TWO SIGMA ADVISERS, LP 0.00% of their portfolio NEW YORK, NY 66,30066.3k $47.3k $47.3k 0.00% Reduced -174.6k -174,600
48 Point72 Asia (Singapore) Pte. Ltd. 0.01% of their portfolio SINGAPORE, U0 61,06861.1k $43.6k $43.6k 0.01% New
49 Vanguard Personalized Indexing Management, LLC 0.00% of their portfolio OAKLAND, CA 60,61760.6k $43.3k $43.3k 0.00% Added +38.6k +38,561
50 CWM, LLC 0.00% of their portfolio OMAHA, NE 56,65756.7k $40.0k $40.0k 0.00% Added +23.9k +23,941
51 Vontobel Holding Ltd. 0.00% of their portfolio ZURICH, V8 50,00050.0k $35.7k $35.7k 0.00% Unchanged
52 PEAK6 LLC 0.00% of their portfolio AUSTIN, TX 42,61242.6k $30.4k $30.4k 0.00% Added +21.3k +21,306
53 Catalyst Funds Management Pty Ltd 0.01% of their portfolio SYDNEY NSW, C3 38,50038.5k $27.5k $27.5k 0.01% New
54 PRUDENTIAL FINANCIAL INC 0.00% of their portfolio NEWARK, NJ 35,50035.5k $25.3k $25.3k 0.00% Reduced -569.1k -569,080
55 CITIGROUP INC 0.00% of their portfolio NEW YORK, NY 28,52828.5k $20.4k $20.4k 0.00% Reduced -36.8k -36,777
56 Tower Research Capital LLC (TRC) 0.00% of their portfolio NEW YORK, NY 24,87924.9k $17.8k $17.8k 0.00% Added +11.2k +11,172
57 HSBC HOLDINGS PLC 0.00% of their portfolio LONDON, X0 24,73924.7k $18.1k $18.1k 0.00% Reduced -35.7k -35,724
58 OneDigital Investment Advisors LLC 0.00% of their portfolio OVERLAND PARK, KS 24,09924.1k $17.2k $17.2k 0.00% Unchanged
59 Hudson Bay Capital Management LP 0.00% of their portfolio STAMFORD, CT 22,57122.6k $16.1k $16.1k 0.00% New
60 WEALTH ENHANCEMENT ADVISORY SERVICES, LLC 0.00% of their portfolio PLYMOUTH, MN 21,20121.2k $16.2k $16.2k 0.00% Added +4.0k +4,002
61 OSAIC HOLDINGS, INC. 0.00% of their portfolio SCOTTSDALE, AZ 21,14921.1k $15.0k $15.0k 0.00% Reduced -1.9k -1,854
62 China Universal Asset Management Co., Ltd. 0.00% of their portfolio SHANGHAI, F4 16,96417.0k $12.1k $12.1k 0.00% Added +424 +424
63 Callan Family Office, LLC 0.00% of their portfolio RADNOR, PA 16,17716.2k $11.5k $11.5k 0.00% New
64 Mariner, LLC 0.00% of their portfolio Overland Park, KS 13,63013.6k $9.7k $9.7k 0.00% New
65 AXXCESS WEALTH MANAGEMENT, LLC 0.00% of their portfolio CARLSBAD, CA 12,90712.9k $9.2k $9.2k 0.00% Unchanged
66 BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.00% of their portfolio HOUSTON, TX 12,90012.9k $9.2k $9.2k 0.00% Unchanged
67 Ground Swell Capital, LLC 0.01% of their portfolio FOLLY BEACH, SC 12,68312.7k $9.1k $9.1k 0.01% New
68 FMR LLC 0.00% of their portfolio BOSTON, MA 11,63911.6k $8.3k $8.3k 0.00% Reduced -49.9k -49,910
69 Pallas Capital Advisors LLC 0.00% of their portfolio BRAINTREE, MA 11,11011.1k $7.9k $7.9k 0.00% New
70 CAPTRUST FINANCIAL ADVISORS 0.00% of their portfolio RALEIGH, NC 10,99811.0k $7.9k $7.9k 0.00% New
71 LAZARD ASSET MANAGEMENT LLC 0.00% of their portfolio NEW YORK, NY 10,94710.9k $7.0k $7.0k 0.00% New
72 Revolve Wealth Partners, LLC 0.00% of their portfolio Hackensack, NJ 10,31210.3k $7.4k $7.4k 0.00% New
73 Quantinno Capital Management LP 0.00% of their portfolio NEW YORK, NY 10,17010.2k $7.3k $7.3k 0.00% New
74 BARCLAYS PLC 0.00% of their portfolio LONDON, X0 6,6186.6k $4.7k $4.7k 0.00% Reduced -109.7k -109,668
75 Cubist Systematic Strategies, LLC 0.00% of their portfolio STAMFORD, CT 6,0786.1k $4.3k $4.3k 0.00% New
76 NewEdge Advisors, LLC 0.00% of their portfolio NEW ORLEANS, LA 4,1134.1k $2.9k $2.9k 0.00% New
77 Gen-Wealth Partners Inc 0.00% of their portfolio ZEELAND, MI 4,0424.0k $2.9k $2.9k 0.00% Unchanged
78 Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio SEOUL, M5 3,2633.3k $2.3k $2.3k 0.00% Added +587 +587
79 BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio PARIS, I0 2,3982.4k $1.7k $1.7k 0.00% Reduced -152.8k -152,837
80 GF FUND MANAGEMENT CO. LTD. 0.00% of their portfolio GUANGZHOU, F4 1,9822.0k $1.4k $1.4k 0.00% Unchanged
81 EverSource Wealth Advisors, LLC 0.00% of their portfolio BIRMINGHAM, AL 1,4711.5k $1.1k $1.1k 0.00% Added +614 +614
82 Physician Wealth Advisors, Inc. 0.00% of their portfolio MIDVALE, UT 1,3041.3k $931 $931 0.00% Unchanged
83 NISA INVESTMENT ADVISORS, LLC 0.00% of their portfolio ST. LOUIS, MO 1,2591.3k $899 $899 0.00% New
84 Accredited Wealth Management, LLC 0.00% of their portfolio LOUISVILLE, KY 1,0001.0k $714 $714 0.00% Unchanged
85 PNC Financial Services Group, Inc. 0.00% of their portfolio Pittsburgh, PA 769769 $549 $549 0.00% Added +103 +103
86 Rise Advisors, LLC 0.00% of their portfolio ROCHESTER, NY 769769 $549 $549 0.00% New
87 Avion Wealth 0.00% of their portfolio THE WOODLANDS, TX 716716 $0 $0 0.00% New
88 Rialto Wealth Management, LLC 0.00% of their portfolio SYRACUSE, NY 707707 $505 $505 0.00% New
89 WELLS FARGO & COMPANY/MN 0.00% of their portfolio SAN FRANCISCO, CA 693693 $495 $495 0.00% Reduced -48.4k -48,441
90 Essential Partners LLC 0.00% of their portfolio RANCHO SANTA FE, CA 654654 $467 $467 0.00% First filing
91 True Wealth Design, LLC 0.00% of their portfolio AKRON, OH 559559 $400 $400 0.00% New
92 RAYMOND JAMES FINANCIAL INC 0.00% of their portfolio ST. PETERSBURG, FL 500500 $357 $357 0.00% New
93 Bogart Wealth, LLC 0.00% of their portfolio MCLEAN, VA 500500 $357 $357 0.00% Unchanged
94 Parallel Advisors, LLC 0.00% of their portfolio SAN FRANCISCO, CA 465465 $332 $332 0.00% Unchanged
95 HighMark Wealth Management LLC 0.00% of their portfolio ST. PAUL, MN 225225 $161 $161 0.00% Unchanged
96 Clearstead Advisors, LLC 0.00% of their portfolio CLEVELAND, OH 121121 $87 $87 0.00% New
97 IFP Advisors, Inc 0.00% of their portfolio TAMPA, FL 7878 $56 $56 0.00% New
98 COMERICA BANK 0.00% of their portfolio DALLAS, TX 4949 $35 $35 0.00% Unchanged
99 GROUP ONE TRADING LLC 0.00% of their portfolio CHICAGO, IL 2020 $14 $14 0.00% New
100 SBI Securities Co., Ltd. 0.00% of their portfolio TOKYO, M0 22 $1 $1 0.00% Reduced -1 -1