STRUCTURE THERAPEUTICS INC GPCR
SPONSORED ADS · ADR · CUSIP 86366E106
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersSouth San Francisco, CA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($1.7m this quarter). Holder counts are more reliable. Implied quarter-end price ≈ $39.63.
Trends to Q2 2023
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q1 2023 | 38 |
| Q2 2023 | 49 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2022 | $0 | $0 | — |
| Q4 2022 | $0 | $0 | — |
| Q1 2023 | $0 | $46.4k | — |
| Q2 2023 | $0 | $0 | — |
Biggest buyers
| Monashee Investment Management LLC | Added | +1.2m |
| PRICE T ROWE ASSOCIATES INC /MD/ | Added | +986.8k |
| Casdin Capital, LLC | Added | +320.0k |
| DEERFIELD MANAGEMENT COMPANY, L.P. | Added | +252.8k |
| Driehaus Capital Management LLC | Added | +195.7k |
| WELLINGTON MANAGEMENT GROUP LLP | Added | +110.4k |
| Point72 Asset Management, L.P. | Added | +81.1k |
| T. Rowe Price Investment Management, Inc. | Added | +56.4k |
| Logos Global Management LP | Added | +50.0k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | New | +40.6k |
Biggest sellers
| FMR LLC | Reduced | -1.3m |
| JANUS HENDERSON GROUP PLC | Reduced | -269.0k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | Reduced | -100.0k |
| Artal Group S.A. | Sold out | -75.0k |
| FRANKLIN RESOURCES INC | Reduced | -74.2k |
| FEDERATED HERMES, INC. | Reduced | -38.1k |
| Octagon Capital Advisors LP | Reduced | -18.7k |
| CITADEL ADVISORS LLC | Reduced | -16.6k |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | Reduced | -11.9k |
| Point72 Middle East FZE | Sold out | -8.5k |
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| FMR LLC 13G · passive investor -1.8 pts · filed 2026-08-06 | 13.2% |
| WELLINGTON MANAGEMENT GROUP LLP 13G · institution -1.8 pts · filed 2026-02-10 | 10.1% |
| Avoro Capital Advisors LLC 13G · institution new · filed 2025-11-14 | 9.4% |
| JANUS HENDERSON GROUP PLC 13G · institution -0.3 pts · filed 2025-11-14 | 7.7% |
| Deep Track Capital, LP 13G · passive investor -1.4 pts · filed 2026-02-13 | 6.0% |
Fell to 5% or below in the last year: BIOTECHNOLOGY VALUE FUND L P (4.9%, 2026-02-17)
Insider purchases and sales in Q2 2023
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
None reported in Q2 2023.
Holders, Q2 2023
| Manager | Shares | Change |
|---|---|---|
| Deep Track Capital, LP 5.14% of their portfolio | 2.6m $110.0m | Unchanged |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.01% of their portfolio | 1.8m $73.7m | Added +986.8k |
| BVF INC/IL 2.03% of their portfolio | 1.8m $72.7m | Unchanged |
| Monashee Investment Management LLC 5.43% of their portfolio | 1.4m $22.8m | Added +1.2m |
| FMR LLC 0.00% of their portfolio | 1.2m $51.5m | Reduced -1.3m |
| Driehaus Capital Management LLC 0.60% of their portfolio | 1.1m $47.2m | Added +195.7k |
| FEDERATED HERMES, INC. 0.10% of their portfolio | 1.0m $42.2m | Reduced -38.1k |
| Casdin Capital, LLC 3.62% of their portfolio | 997.0k $41.4m | Added +320.0k |
| T. Rowe Price Investment Management, Inc. 0.02% of their portfolio | 654.5k $27.2m | Added +56.4k |
| DEERFIELD MANAGEMENT COMPANY, L.P. 0.56% of their portfolio | 627.8k $26.1m | Added +252.8k |
| Cormorant Asset Management, LP 1.36% of their portfolio | 576.4k $24.0m | Unchanged |
| Point72 Asset Management, L.P. 0.06% of their portfolio | 431.0k $17.9m | Added +81.1k |
| Logos Global Management LP 2.30% of their portfolio | 400.0k $16.6m | Added +50.0k |
| JENNISON ASSOCIATES LLC 0.01% of their portfolio | 399.8k $16.6m | Unchanged |
| BlackRock Inc. 0.00% of their portfolio | 394.8k $16.4m | Reduced -5.2k |
| TCG Crossover Management, LLC 2.39% of their portfolio | 350.0k $14.5m | Unchanged |
| CITADEL ADVISORS LLC 0.02% of their portfolio | 349.7k $14.5m | Reduced -16.6k |
| FRANKLIN RESOURCES INC 0.00% of their portfolio | 250.8k $10.4m | Reduced -74.2k |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 210.3k $8.7m | Added +110.4k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.02% of their portfolio | 192.4k $8.0m | Reduced -100.0k |
| Woodline Partners LP 0.08% of their portfolio | 170.0k $7.1m | Unchanged |
| JANUS HENDERSON GROUP PLC 0.00% of their portfolio | 77.4k $3.2m | Reduced -269.0k |
| Octagon Capital Advisors LP 0.44% of their portfolio | 75.0k $3.1m | Reduced -18.7k |
| TD Asset Management Inc 0.00% of their portfolio | 72.7k $3.0m | Added +36.8k |
| Nantahala Capital Management, LLC 0.25% of their portfolio | 50.0k $2.1m | Unchanged |
| ArrowMark Colorado Holdings LLC 0.02% of their portfolio | 50.0k $2.1m | Unchanged |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 44.2k $1.8m | Added +8.8k |
| PRUDENTIAL FINANCIAL INC 0.00% of their portfolio | 42.0k $1.7m | Unchanged |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 40.6k $1.7m | New |
| Avidity Partners Management LP 0.05% of their portfolio | 37.8k $1.6m | New |
| SVB FINANCIAL GROUP 2.78% of their portfolio | 35.4k $1.5m | Unchanged |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 32.9k $1.4m | New |
| China Universal Asset Management Co., Ltd. 0.35% of their portfolio | 27.3k $1.1m | New |
| Maven Securities LTD 0.15% of their portfolio | 25.0k $1.0m | New |
| Lynx1 Capital Management LP 0.63% of their portfolio | 23.0k $956.1k | Unchanged |
| Weiss Multi-Strategy Advisers LLC 0.01% of their portfolio | 15.2k $631.0k | New |
| PLATINUM INVESTMENT MANAGEMENT LTD 0.02% of their portfolio | 15.0k $623.5k | Unchanged |
| STATE STREET CORP 0.00% of their portfolio | 11.5k $476.4k | New |
| FRED ALGER MANAGEMENT, LLC 0.00% of their portfolio | 10.5k $437.0k | New |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 10.3k $426.4k | New |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) 0.01% of their portfolio | 10.2k $423.7k | Reduced -11.9k |
| VIRTUS ADVISERS, LLC 0.09% of their portfolio | 3.5k $146.0k | New |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 1.7k $70.0k | New |
| BARCLAYS PLC 0.00% of their portfolio | 1.1k $47.1k | New |
| Pinpoint Asset Management Ltd 0.00% of their portfolio | 900 $37.0k | New |
| SIGNATUREFD, LLC 0.00% of their portfolio | 100 $4.2k | Unchanged |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 67 $2.8k | Reduced -33 |
| UBS Group AG 0.00% of their portfolio | 2 $83 | New |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. 0.00% of their portfolio | 0 $0 | New |