Vault-13

STRUCTURE THERAPEUTICS INC GPCR

SPONSORED ADS · ADR · CUSIP 86366E106

49 institutional holders +11 vs Q1 2023
17,605,28717.6m shares reported held*
$697.6mreported value*
15 new 11 added 10 reduced 4 sold out net bought ≈ $42.5m (+1.6m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($1.7m this quarter). Holder counts are more reliable. Implied quarter-end price ≈ $39.63.

Trends to Q2 2023

Institutional holders

Managers reporting a position, each quarter

0204060Q1 23: 38Q2 23: 4949Q1 23Q2 23
Numbers
QuarterHolders
Q1 202338
Q2 202349

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$20k$40k$60kQ3 22 calls: $0Q3 22 puts: $0Q3 22P/C —Q4 22 calls: $0Q4 22 puts: $0Q4 22P/C —Q1 23 calls: $0Q1 23 puts: $46.4kQ1 23P/C —Q2 23 calls: $0Q2 23 puts: $0Q2 23P/C —
Numbers
QuarterCallsPutsP/C
Q3 2022$0$0—
Q4 2022$0$0—
Q1 2023$0$46.4k—
Q2 2023$0$0—

Biggest buyers

Monashee Investment Management LLC Added +1,200,991+1.2m
PRICE T ROWE ASSOCIATES INC /MD/ Added +986,845+986.8k
Casdin Capital, LLC Added +320,000+320.0k
DEERFIELD MANAGEMENT COMPANY, L.P. Added +252,813+252.8k
Driehaus Capital Management LLC Added +195,708+195.7k
WELLINGTON MANAGEMENT GROUP LLP Added +110,370+110.4k
Point72 Asset Management, L.P. Added +81,138+81.1k
T. Rowe Price Investment Management, Inc. Added +56,408+56.4k
Logos Global Management LP Added +50,000+50.0k
MANUFACTURERS LIFE INSURANCE COMPANY, THE New +40,631+40.6k

Biggest sellers

FMR LLC Reduced -1,261,117-1.3m
JANUS HENDERSON GROUP PLC Reduced -268,991-269.0k
ADAGE CAPITAL PARTNERS GP, L.L.C. Reduced -100,000-100.0k
Artal Group S.A. Sold out -75,000-75.0k
FRANKLIN RESOURCES INC Reduced -74,191-74.2k
FEDERATED HERMES, INC. Reduced -38,102-38.1k
Octagon Capital Advisors LP Reduced -18,692-18.7k
CITADEL ADVISORS LLC Reduced -16,624-16.6k
OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) Reduced -11,857-11.9k
Point72 Middle East FZE Sold out -8,474-8.5k

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
FMR LLC 13G · passive investor -1.8 pts · filed 2026-08-06 13.2% -1.8 pts 28.2m 2026-08-06
WELLINGTON MANAGEMENT GROUP LLP 13G · institution -1.8 pts · filed 2026-02-10 10.1% -1.8 pts 21.4m 2026-02-10
Avoro Capital Advisors LLC 13G · institution new · filed 2025-11-14 9.4% new 16.2m 2025-11-14
JANUS HENDERSON GROUP PLC 13G · institution -0.3 pts · filed 2025-11-14 7.7% -0.3 pts 4.4m 2025-11-14
Deep Track Capital, LP 13G · passive investor -1.4 pts · filed 2026-02-13 6.0% -1.4 pts 12.3m 2026-02-13

Fell to 5% or below in the last year: BIOTECHNOLOGY VALUE FUND L P (4.9%, 2026-02-17)

Insider purchases and sales in Q2 2023

Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.

None reported in Q2 2023.

Holders, Q2 2023

#ManagerLocationShares Value% of their portfolioChangeShares change
1 Deep Track Capital, LP 5.14% of their portfolio GREENWICH, CT 2,646,7822.6m $110.0m $110.0m 5.14% Unchanged
2 PRICE T ROWE ASSOCIATES INC /MD/ 0.01% of their portfolio BALTIMORE, MD 1,773,3501.8m $73.7m $73.7m 0.01% Added +986.8k +986,845
3 BVF INC/IL 2.03% of their portfolio San Francisco, CA 1,750,0001.8m $72.7m $72.7m 2.03% Unchanged
4 Monashee Investment Management LLC 5.43% of their portfolio Boston, MA 1,370,9911.4m $22.8m $22.8m 5.43% Added +1.2m +1,200,991
5 FMR LLC 0.00% of their portfolio BOSTON, MA 1,237,7351.2m $51.5m $51.5m 0.00% Reduced -1.3m -1,261,117
6 Driehaus Capital Management LLC 0.60% of their portfolio Chicago, IL 1,135,9361.1m $47.2m $47.2m 0.60% Added +195.7k +195,708
7 FEDERATED HERMES, INC. 0.10% of their portfolio PITTSBURGH, PA 1,014,7001.0m $42.2m $42.2m 0.10% Reduced -38.1k -38,102
8 Casdin Capital, LLC 3.62% of their portfolio New York, NY 997,017997.0k $41.4m $41.4m 3.62% Added +320.0k +320,000
9 T. Rowe Price Investment Management, Inc. 0.02% of their portfolio BALTIMORE, MD 654,516654.5k $27.2m $27.2m 0.02% Added +56.4k +56,408
10 DEERFIELD MANAGEMENT COMPANY, L.P. 0.56% of their portfolio New York, NY 627,813627.8k $26.1m $26.1m 0.56% Added +252.8k +252,813
11 Cormorant Asset Management, LP 1.36% of their portfolio BOSTON, MA 576,373576.4k $24.0m $24.0m 1.36% Unchanged
12 Point72 Asset Management, L.P. 0.06% of their portfolio STAMFORD, CT 431,000431.0k $17.9m $17.9m 0.06% Added +81.1k +81,138
13 Logos Global Management LP 2.30% of their portfolio San Francisco, CA 400,000400.0k $16.6m $16.6m 2.30% Added +50.0k +50,000
14 JENNISON ASSOCIATES LLC 0.01% of their portfolio NEW YORK, NY 399,780399.8k $16.6m $16.6m 0.01% Unchanged
15 BlackRock Inc. 0.00% of their portfolio New York, NY 394,846394.8k $16.4m $16.4m 0.00% Reduced -5.2k -5,154
16 TCG Crossover Management, LLC 2.39% of their portfolio PALO ALTO, CA 350,000350.0k $14.5m $14.5m 2.39% Unchanged
17 CITADEL ADVISORS LLC 0.02% of their portfolio MIAMI, FL 349,663349.7k $14.5m $14.5m 0.02% Reduced -16.6k -16,624
18 FRANKLIN RESOURCES INC 0.00% of their portfolio San Mateo, CA 250,809250.8k $10.4m $10.4m 0.00% Reduced -74.2k -74,191
19 WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio Boston, MA 210,269210.3k $8.7m $8.7m 0.00% Added +110.4k +110,370
20 ADAGE CAPITAL PARTNERS GP, L.L.C. 0.02% of their portfolio Boston, MA 192,398192.4k $8.0m $8.0m 0.02% Reduced -100.0k -100,000
21 Woodline Partners LP 0.08% of their portfolio San Francisco, CA 170,000170.0k $7.1m $7.1m 0.08% Unchanged
22 JANUS HENDERSON GROUP PLC 0.00% of their portfolio LONDON, X0 77,43077.4k $3.2m $3.2m 0.00% Reduced -269.0k -268,991
23 Octagon Capital Advisors LP 0.44% of their portfolio NEW YORK, NY 75,00075.0k $3.1m $3.1m 0.44% Reduced -18.7k -18,692
24 TD Asset Management Inc 0.00% of their portfolio Toronto, A6 72,70972.7k $3.0m $3.0m 0.00% Added +36.8k +36,763
25 Nantahala Capital Management, LLC 0.25% of their portfolio NEW CANAAN, CT 50,00050.0k $2.1m $2.1m 0.25% Unchanged
26 ArrowMark Colorado Holdings LLC 0.02% of their portfolio Denver, CO 50,00050.0k $2.1m $2.1m 0.02% Unchanged
27 MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio NEW YORK, NY 44,22644.2k $1.8m $1.8m 0.00% Added +8.8k +8,767
28 PRUDENTIAL FINANCIAL INC 0.00% of their portfolio NEWARK, NJ 42,00042.0k $1.7m $1.7m 0.00% Unchanged
29 MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio Toronto, A6 40,63140.6k $1.7m $1.7m 0.00% New
30 Avidity Partners Management LP 0.05% of their portfolio DALLAS, TX 37,80037.8k $1.6m $1.6m 0.05% New
31 SVB FINANCIAL GROUP 2.78% of their portfolio Dallas, TX 35,35335.4k $1.5m $1.5m 2.78% Unchanged
32 RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio NEW YORK, NY 32,90032.9k $1.4m $1.4m 0.00% New
33 China Universal Asset Management Co., Ltd. 0.35% of their portfolio SHANGHAI, F4 27,26727.3k $1.1m $1.1m 0.35% New
34 Maven Securities LTD 0.15% of their portfolio ST HELIER, Y9 25,00025.0k $1.0m $1.0m 0.15% New
35 Lynx1 Capital Management LP 0.63% of their portfolio DORADO, PR 23,00023.0k $956.1k $956.1k 0.63% Unchanged
36 Weiss Multi-Strategy Advisers LLC 0.01% of their portfolio NEW YORK, NY 15,17315.2k $631.0k $631.0k 0.01% New
37 PLATINUM INVESTMENT MANAGEMENT LTD 0.02% of their portfolio SYDNEY AUSTRALIA 2000, C3 15,00015.0k $623.5k $623.5k 0.02% Unchanged
38 STATE STREET CORP 0.00% of their portfolio BOSTON, MA 11,46011.5k $476.4k $476.4k 0.00% New
39 FRED ALGER MANAGEMENT, LLC 0.00% of their portfolio NEW YORK, NY 10,51210.5k $437.0k $437.0k 0.00% New
40 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 10,25710.3k $426.4k $426.4k 0.00% New
41 OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) 0.01% of their portfolio CHICAGO, IL 10,19310.2k $423.7k $423.7k 0.01% Reduced -11.9k -11,857
42 VIRTUS ADVISERS, LLC 0.09% of their portfolio HARTFORD, CT 3,5133.5k $146.0k $146.0k 0.09% New
43 BANK OF AMERICA CORP /DE/ 0.00% of their portfolio CHARLOTTE, NC 1,6841.7k $70.0k $70.0k 0.00% New
44 BARCLAYS PLC 0.00% of their portfolio LONDON, X0 1,1321.1k $47.1k $47.1k 0.00% New
45 Pinpoint Asset Management Ltd 0.00% of their portfolio HONG KONG, K3 900900 $37.0k $37.0k 0.00% New
46 SIGNATUREFD, LLC 0.00% of their portfolio ATLANTA, GA 100100 $4.2k $4.2k 0.00% Unchanged
47 Tower Research Capital LLC (TRC) 0.00% of their portfolio NEW YORK, NY 6767 $2.8k $2.8k 0.00% Reduced -33 -33
48 UBS Group AG 0.00% of their portfolio ZURICH, V8 22 $83 $83 0.00% New
49 CONCOURSE FINANCIAL GROUP SECURITIES, INC. 0.00% of their portfolio BIRMINGHAM, AL 00 $0 $0 0.00% New