SOLID BIOSCIENCES INC SLDB
COM NEW · Common Stock · CUSIP 83422E204
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersCharlestown, MA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($258.1k this quarter). Holder counts are more reliable. Shares outstanding: 107.2m as of 2026-08-04, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $9.99. Options: 4 managers hold calls ($1.7m notional), 1 hold puts ($132.9k).
Trends to Q2 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q4 2022 | 34 |
| Q1 2023 | 38 |
| Q2 2023 | 35 |
| Q3 2023 | 37 |
| Q4 2023 | 40 |
| Q1 2024 | 56 |
| Q2 2024 | 80 |
| Q3 2024 | 92 |
| Q4 2024 | 90 |
| Q1 2025 | 122 |
| Q2 2025 | 112 |
| Q3 2025 | 124 |
| Q4 2025 | 126 |
| Q1 2026 | 144 |
| Q2 2026 | 156 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2024 | 52 | 34 |
| Q4 2024 | 47 | 38 |
| Q1 2025 | 90 | 29 |
| Q2 2025 | 76 | 48 |
| Q3 2025 | 63 | 49 |
| Q4 2025 | 50 | 57 |
| Q1 2026 | 79 | 53 |
| Q2 2026 | 97 | 63 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2025 | $4.3m | $276.7k | 0.06 |
| Q4 2025 | $3.5m | $14.7k | 0.00 |
| Q1 2026 | $2.2m | $1.1m | 0.51 |
| Q2 2026 | $1.7m | $132.9k | 0.08 |
Biggest buyers
| RTW INVESTMENTS, LP | New | +3.9m |
| FMR LLC | Added | +3.3m |
| STATE STREET CORP | Added | +3.0m |
| RA CAPITAL MANAGEMENT, L.P. | Added | +2.7m |
| BlackRock, Inc. | Added | +2.0m |
| VANGUARD CAPITAL MANAGEMENT LLC | Added | +1.3m |
| FRANKLIN RESOURCES INC | Added | +1.2m |
| ARMISTICE CAPITAL, LLC | Added | +1.1m |
| SILVERARC CAPITAL MANAGEMENT, LLC | New | +668.5k |
| GOLDMAN SACHS GROUP INC | Added | +667.4k |
Biggest sellers
| Vestal Point Capital, LP | Reduced | -2.8m |
| Point72 Asset Management, L.P. | Reduced | -1.6m |
| Nantahala Capital Management, LLC | Sold out | -1.2m |
| Monashee Investment Management LLC | Reduced | -920.3k |
| Ally Bridge Group (NY) LLC | Reduced | -511.0k |
| MILLENNIUM MANAGEMENT LLC | Sold out | -363.7k |
| Parkman Healthcare Partners LLC | Sold out | -308.8k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | Reduced | -250.0k |
| Ikarian Capital, LLC | Reduced | -221.5k |
| AMERIPRISE FINANCIAL INC | Reduced | -213.1k |
Biggest calls
| GOLDMAN SACHS GROUP INC | New | $999.0k100.0k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $373.6k37.4k shares |
| CITADEL ADVISORS LLC | Reduced | $308.7k30.9k shares |
| SIMPLEX TRADING, LLC | Added | $44.0k4.4k shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $132.9k13.3k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| RA CAPITAL MANAGEMENT, L.P. 13D · may seek influence +2.0 pts · filed 2026-06-24 | 11.9% |
| PERCEPTIVE ADVISORS LLC 13D · may seek influence -1.7 pts · filed 2026-08-14 | 11.2% |
| Invus Global Management, LLC 13G · passive investor +0.4 pts · filed 2026-05-05 | 10.0% |
| FMR LLC 13G · institution new · filed 2026-08-06 | 7.0% |
| BlackRock, Inc. 13G · institution +1.8 pts · filed 2026-07-30 | 6.5% |
Fell to 5% or below in the last year: Vestal Point Capital, LP (4.8%, 2026-08-14), Adage Capital Management, L.P. (1.8%, 2026-02-12)
Insider purchases and sales since 1 Apr 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2024 | 0 | — | 5 | $151.0k | — |
| Q1 2025 | 2 | $20.2m | 7 | $142.9k | $122.5k |
| Q2 2025 | 0 | — | 0 | — | — |
| Q3 2025 | 0 | — | 0 | — | — |
| Q4 2025 | 0 | — | 6 | $147.9k | $117.1k |
| Q1 2026 | 0 | — | 7 | $2.5m | $2.5m |
| Q2 2026 | 0 | — | 0 | — | — |
| Q3 2026 | 0 | — | 0 | — | — |
None reported since 1 Apr 2026.
Holders, Q2 2026
| Manager | Shares | Change |
|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. 1.04% of their portfolio | 12.0m $120.2m | Added +2.7m |
| PERCEPTIVE ADVISORS LLC 1.85% of their portfolio | 11.9m $118.9m | Unchanged |
| Bain Capital Life Sciences Investors, LLC 5.83% of their portfolio | 9.8m $98.0m | Unchanged |
| Siren, L.L.C. 1.56% of their portfolio | 7.7m $76.8m | Unchanged |
| BlackRock, Inc. 0.00% of their portfolio | 6.9m $69.3m | Added +2.0m |
| FMR LLC 0.00% of their portfolio | 6.9m $68.7m | Added +3.3m |
| ARMISTICE CAPITAL, LLC 1.18% of their portfolio | 4.3m $42.7m | Added +1.1m |
| STATE STREET CORP 0.00% of their portfolio | 4.2m $41.7m | Added +3.0m |
| Jupiter Topco LLC 0.02% of their portfolio | 4.0m $40.4m | First filing |
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 4.0m $40.1m | Added +1.3m |
| RTW INVESTMENTS, LP 0.33% of their portfolio | 3.9m $38.9m | New |
| Deep Track Capital, LP 0.52% of their portfolio | 3.6m $35.6m | Unchanged |
| FRANKLIN RESOURCES INC 0.01% of their portfolio | 3.4m $34.4m | Added +1.2m |
| CITADEL ADVISORS LLC 0.02% of their portfolio | 2.8m $28.1m | Added +218.3k |
| Alyeska Investment Group, L.P. 0.06% of their portfolio | 2.3m $22.8m | Added +359 |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 2.2m $22.2m | Reduced -213.1k |
| Vestal Point Capital, LP 0.50% of their portfolio | 2.2m $21.6m | Reduced -2.8m |
| Redmile Group, LLC 1.31% of their portfolio | 1.9m $19.5m | Reduced -63.2k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 1.9m $19.4m | Added +644.8k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 1.6m $16.0m | Added +667.4k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.02% of their portfolio | 1.5m $15.0m | Reduced -250.0k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 1.3m $12.6m | Added +310.2k |
| BLAIR WILLIAM & CO/IL 0.02% of their portfolio | 756.3k $7.6m | Added +105.1k |
| VANGUARD PORTFOLIO MANAGEMENT LLC 0.00% of their portfolio | 748.6k $7.5m | Added +410.0k |
| Woodline Partners LP 0.02% of their portfolio | 674.1k $6.7m | Added +179.0k |
| SILVERARC CAPITAL MANAGEMENT, LLC 0.74% of their portfolio | 668.5k $6.7m | New |
| Birchview Capital, LP 3.11% of their portfolio | 666.2k $6.7m | Added +40.2k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 603.6k $6.0m | Added +185.4k |
| MOORE CAPITAL MANAGEMENT, LP 0.14% of their portfolio | 603.5k $6.0m | Added +278.7k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 524.1k $5.2m | Added +137.3k |
| Monashee Investment Management LLC 8.38% of their portfolio | 500.0k $5.0m | Reduced -920.3k |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 494.7k $4.9m | Added +168.8k |
| Point72 Asset Management, L.P. 0.01% of their portfolio | 448.0k $4.5m | Reduced -1.6m |
| STEMPOINT CAPITAL LP 0.62% of their portfolio | 358.8k $3.6m | Reduced -32.0k |
| Boxer Capital Management, LLC 0.23% of their portfolio | 300.0k $3.0m | Unchanged |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 281.7k $2.7m | Added +5.3k |
| Ally Bridge Group (NY) LLC 3.30% of their portfolio | 256.0k $2.6m | Reduced -511.0k |
| MORGAN STANLEY 0.00% of their portfolio | 255.2k $2.5m | Reduced -5.9k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 244.4k $2.4m | Added +83.7k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 243.2k $2.4m | Added +105.2k |
| J. Goldman & Co LP 0.09% of their portfolio | 242.2k $2.4m | Reduced -42.3k |
| Nuveen, LLC 0.00% of their portfolio | 241.6k $2.4m | Reduced -158.7k |
| D. E. Shaw & Co., Inc. 0.00% of their portfolio | 222.8k $2.2m | Added +94.4k |
| UBS Group AG 0.00% of their portfolio | 188.3k $1.9m | Added +89.4k |
| ALGERT GLOBAL LLC 0.02% of their portfolio | 187.4k $1.9m | Added +114.8k |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 185.4k $1.9m | Added +24.1k |
| Balyasny Asset Management L.P. 0.00% of their portfolio | 178.3k $1.8m | Unchanged |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 163.0k $1.6m | Reduced -106.7k |
| Apis Capital Advisors, LLC 0.16% of their portfolio | 160.0k $1.6m | Unchanged |
| Soleus Capital Management, L.P. 0.05% of their portfolio | 150.0k $1.5m | New |
| CITIGROUP INC 0.00% of their portfolio | 148.4k $1.5m | Added +79.1k |
| Invesco Ltd. 0.00% of their portfolio | 143.4k $1.4m | Reduced -197.5k |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 137.1k $1.4m | Reduced -14.5k |
| Qube Research & Technologies Ltd 0.00% of their portfolio | 136.9k $1.4m | New |
| Y-Intercept (Hong Kong) Ltd 0.02% of their portfolio | 109.9k $1.1m | New |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 108.2k $1.1m | Reduced -109.0k |
| Susquehanna Portfolio Strategies, LLC 0.02% of their portfolio | 107.3k $1.1m | Reduced -90.3k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 105.1k $1.0m | Added +23.0k |
| Fisher Asset Management, LLC 0.00% of their portfolio | 103.5k $1.0m | Unchanged |
| ALPS ADVISORS INC 0.00% of their portfolio | 99.9k $998.2k | New |
| XTX Topco Ltd 0.01% of their portfolio | 89.0k $889.5k | Added +12.5k |
| Jump Financial, LLC 0.01% of their portfolio | 88.2k $880.6k | New |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 82.1k $820.2k | Reduced -42.2k |
| Verition Fund Management LLC 0.01% of their portfolio | 81.3k $811.9k | New |
| Quadrature Capital Ltd 0.01% of their portfolio | 78.3k $782.1k | New |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 77.5k $774.6k | Added +31.3k |
| Quantum Private Wealth, LLC 0.19% of their portfolio | 73.9k $738.2k | Reduced -16.3k |
| Rafferty Asset Management, LLC 0.00% of their portfolio | 71.8k $717.1k | New |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 69.3k $498.7k | Unchanged |
| Trexquant Investment LP 0.00% of their portfolio | 69.1k $690.6k | Reduced -54.8k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 68.8k $686.9k | Added +36.5k |
| BARCLAYS PLC 0.00% of their portfolio | 65.0k $649.4k | Added +6.1k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 64.6k $646.0k | Added +24.3k |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 62.2k $621.5k | Reduced -52.2k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 61.8k $617.2k | Reduced -35.2k |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 60.7k $606.4k | Reduced -31.5k |
| DeepCurrents Investment Group LLC 0.02% of their portfolio | 59.2k $591.1k | New |
| Vanguard Global Advisers, LLC 0.00% of their portfolio | 58.6k $585.3k | Added +22.2k |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 57.6k $575.6k | Added +12.0k |
| Knott David M Jr 0.30% of their portfolio | 56.2k $561.5k | Added +9.1k |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 48.3k $482.5k | Added +39.4k |
| BANK OF NOVA SCOTIA 0.00% of their portfolio | 47.2k $471.5k | New |
| MetLife Investment Management, LLC 0.00% of their portfolio | 46.2k $461.1k | Added +19.7k |
| Virtus Investment Advisers, LLC 0.11% of their portfolio | 45.8k $457.8k | New |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 44.6k $441.0k | Added +16.6k |
| Ikarian Capital, LLC 0.07% of their portfolio | 43.0k $429.1k | Reduced -221.5k |
| Quantinno Capital Management LP 0.00% of their portfolio | 40.1k $401.0k | New |
| LOS ANGELES CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 36.9k $368.8k | Reduced -500 |
| PROFUND ADVISORS LLC 0.01% of their portfolio | 36.5k $365.1k | New |
| Creative Planning 0.00% of their portfolio | 35.9k $358.2k | Added +1.3k |
| CIBC Bancorp USA Inc. 0.00% of their portfolio | 35.0k $349.4k | Added +1.4k |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC 0.01% of their portfolio | 33.3k $332.6k | New |
| ArchPoint Investors 0.07% of their portfolio | 31.3k $312.9k | New |
| Engineers Gate Manager LP 0.00% of their portfolio | 28.9k $288.9k | Added +7.4k |
| HSBC HOLDINGS PLC 0.00% of their portfolio | 27.8k $285.3k | Reduced -11.7k |
| Atom Investors LP 0.02% of their portfolio | 27.2k $271.5k | New |
| Police & Firemen's Retirement System of New Jersey 0.00% of their portfolio | 23.2k $231.9k | Added +5.8k |
| SFMG, LLC 0.01% of their portfolio | 22.2k $221.3k | Unchanged |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 21.2k $212.2k | Added +5.0k |
| BOOTHBAY FUND MANAGEMENT, LLC 0.00% of their portfolio | 19.9k $199.3k | Reduced -67.1k |