Vault-13

SOLENO THERAPEUTICS INC SLNO

COM · Common Stock · CUSIP 834203309

99 institutional holders +22 vs Q4 2023
35,194,96935.2m shares reported held*
$1.5bnreported value*
32 new 40 added 16 reduced 10 sold out net bought ≈ $37.5m (+877.3k shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Implied quarter-end price ≈ $42.76. Options: 7 managers hold calls ($17.1m notional), 7 hold puts ($4.1m).

Trends to Q1 2024

Institutional holders

Managers reporting a position, each quarter

050100Q3 22: 20Q4 22: 26Q1 23: 21Q2 23: 23Q3 23: 55Q4 23: 77Q1 24: 9999Q3 22Q1 23Q3 23Q1 24
Numbers
QuarterHolders
Q3 202220
Q4 202226
Q1 202321
Q2 202323
Q3 202355
Q4 202377
Q1 202499

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
1000100Q4 22: 12 bought or addedQ4 22: 9 cut or sold outQ4 22Q1 23: 8 bought or addedQ1 23: 9 cut or sold outQ1 23Q2 23: 6 bought or addedQ2 23: 9 cut or sold outQ2 23Q3 23: 41 bought or addedQ3 23: 12 cut or sold outQ3 23Q4 23: 55 bought or addedQ4 23: 22 cut or sold outQ4 23Q1 24: 72 bought or addedQ1 24: 26 cut or sold outQ1 24
Numbers
QuarterBought or addedCut or sold out
Q4 2022129
Q1 202389
Q2 202369
Q3 20234112
Q4 20235522
Q1 20247226

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$5m$10m$15m$20mQ2 23 calls: $0Q2 23 puts: $0Q2 23P/C —Q3 23 calls: $0Q3 23 puts: $0Q3 23P/C —Q4 23 calls: $2.5mQ4 23 puts: $4.0mQ4 23P/C 1.62Q1 24 calls: $17.1mQ1 24 puts: $4.1mQ1 24P/C 0.24
Numbers
QuarterCallsPutsP/C
Q2 2023$0$0—
Q3 2023$0$0—
Q4 2023$2.5m$4.0m1.62
Q1 2024$17.1m$4.1m0.24

Biggest buyers

Carlyle Group Inc. Added +1,213,758+1.2m
Avoro Capital Advisors LLC Added +840,000+840.0k
STATE STREET CORP Added +469,168+469.2k
Frazier Life Sciences Management, L.P. Added +410,730+410.7k
JANUS HENDERSON GROUP PLC Added +346,914+346.9k
Pictet Asset Management Holding SA New +333,852+333.9k
Invesco Ltd. New +320,030+320.0k
MORGAN STANLEY Added +210,635+210.6k
MARSHALL WACE, LLP New +176,237+176.2k
PRICE T ROWE ASSOCIATES INC /MD/ New +152,620+152.6k

Biggest sellers

Nantahala Capital Management, LLC Reduced -3,302,323-3.3m
Balyasny Asset Management L.P. Reduced -775,258-775.3k
Commodore Capital LP Reduced -530,467-530.5k
FARALLON CAPITAL MANAGEMENT, L.L.C. Reduced -137,469-137.5k
Woodline Partners LP Reduced -93,540-93.5k
SAMLYN CAPITAL, LLC Reduced -82,850-82.8k
SILVERARC CAPITAL MANAGEMENT, LLC Sold out -73,665-73.7k
J. Goldman & Co LP Sold out -73,252-73.3k
Cubist Systematic Strategies, LLC Sold out -57,006-57.0k
Vestal Point Capital, LP Reduced -50,000-50.0k

Biggest calls

SUSQUEHANNA INTERNATIONAL GROUP, LLP Added $11.0m256.8k shares
Ikarian Capital, LLC Added $3.5m81.1k shares
CITADEL ADVISORS LLC Added $1.5m34.4k shares
BOOTHBAY FUND MANAGEMENT, LLC Added $924.5k21.6k shares
SIMPLEX TRADING, LLC Added $273.0k6.4k shares
Cutler Group LLC / CA New $3.0k3.4k shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares

Biggest puts

Caption Management, LLC Added $2.6m60.0k shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Reduced $813.2k19.0k shares
CITADEL ADVISORS LLC Added $419.4k9.8k shares
WOLVERINE TRADING, LLC New $308.2k7.2k shares
SIMPLEX TRADING, LLC Reduced $29.0k700 shares
Cutler Group LLC / CA New $1.0k100 shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
BlackRock, Inc. 13G · institution +1.4 pts · filed 2026-04-24 6.9% +1.4 pts 3.5m 2026-04-24
ADAGE CAPITAL PARTNERS GP, L.L.C. 13G · institution filed 2025-02-12 6.4% 2.8m 2025-02-12
STATE STREET CORP 13G · institution new · filed 2026-05-12 5.2% new 2.7m 2026-05-12

Fell to 5% or below in the last year: WELLINGTON MANAGEMENT GROUP LLP (0.0%, 2026-08-13), PRICE T ROWE ASSOCIATES INC /MD/ (2.0%, 2026-05-15), Avoro Capital Advisors LLC (4.5%, 2026-05-15), JANUS HENDERSON GROUP PLC (2.3%, 2026-05-07), FMR LLC (0.4%, 2026-05-07), VANGUARD GROUP INC (0.0%, 2026-03-27), Vivo Opportunity Fund Holdings, L.P. (4.2%, 2025-11-14), Adage Capital Management, L.P. (2.6%, 2025-11-13; now reported by ADAGE CAPITAL PARTNERS GP, L.L.C.)

Holders, Q1 2024

#ManagerLocationShares Value% of their portfolioChangeShares change
1 Vivo Capital, LLC 28.31% of their portfolio Palo Alto, CA 8,418,0938.4m $360.3m $360.3m 28.31% Unchanged
2 Carlyle Group Inc. 10.91% of their portfolio WASHINGTON, DC 4,071,5624.1m $173.1m $173.1m 10.91% Added +1.2m +1,213,758
3 PERCEPTIVE ADVISORS LLC 2.32% of their portfolio NEW YORK, NY 3,074,5423.1m $131.6m $131.6m 2.32% Unchanged
4 JANUS HENDERSON GROUP PLC 0.07% of their portfolio LONDON, X0 2,870,8112.9m $122.7m $122.7m 0.07% Added +346.9k +346,914
5 Nantahala Capital Management, LLC 10.11% of their portfolio NEW CANAAN, CT 2,410,3792.4m $103.2m $103.2m 10.11% Reduced -3.3m -3,302,323
6 ADAGE CAPITAL PARTNERS GP, L.L.C. 0.16% of their portfolio Boston, MA 1,943,5201.9m $83.2m $83.2m 0.16% Added +116.7k +116,706
7 Avoro Capital Advisors LLC 0.81% of their portfolio NEW YORK, NY 1,625,0001.6m $69.5m $69.5m 0.81% Added +840.0k +840,000
8 Vestal Point Capital, LP 4.42% of their portfolio NEW YORK, NY 1,250,0001.2m $53.5m $53.5m 4.42% Reduced -50.0k -50,000
9 STATE STREET CORP 0.00% of their portfolio BOSTON, MA 970,570970.6k $41.5m $41.5m 0.00% Added +469.2k +469,168
10 VANGUARD GROUP INC 0.00% of their portfolio Valley Forge, PA 969,655969.7k $41.5m $41.5m 0.00% Added +33 +33
11 Frazier Life Sciences Management, L.P. 1.58% of their portfolio PALO ALTO, CA 875,667875.7k $37.5m $37.5m 1.58% Added +410.7k +410,730
12 Ikarian Capital, LLC 6.58% of their portfolio DALLAS, TX 565,411565.4k $24.2m $24.2m 6.58% Reduced -24.8k -24,832
13 WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio Boston, MA 353,481353.5k $15.1m $15.1m 0.00% Added +140.9k +140,875
14 Ally Bridge Group (NY) LLC 8.01% of their portfolio NEW YORK, NY 336,486336.5k $14.4m $14.4m 8.01% Added +26.5k +26,536
15 Pictet Asset Management Holding SA 0.02% of their portfolio CAROUGE, V8 333,852333.9k $14.3m $14.3m 0.02% New
16 BlackRock Inc. 0.00% of their portfolio New York, NY 326,298326.3k $14.0m $14.0m 0.00% Added +12.6k +12,637
17 Invesco Ltd. 0.00% of their portfolio ATLANTA, GA 320,030320.0k $13.7m $13.7m 0.00% New
18 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 312,009312.0k $13.4m $13.4m 0.00% Added +210.6k +210,635
19 EMERALD ADVISERS, LLC 0.52% of their portfolio LEOLA, PA 300,376300.4k $12.9m $12.9m 0.52% Added +48.2k +48,223
20 EMERALD MUTUAL FUND ADVISERS TRUST 0.52% of their portfolio LEOLA, PA 231,761231.8k $9.9m $9.9m 0.52% Added +30.4k +30,435
21 SAMLYN CAPITAL, LLC 0.16% of their portfolio New York, NY 218,927218.9k $9.4m $9.4m 0.16% Reduced -82.8k -82,850
22 GOLDMAN SACHS GROUP INC 0.00% of their portfolio NEW YORK, NY 211,917211.9k $9.1m $9.1m 0.00% Added +143.3k +143,318
23 Ghost Tree Capital, LLC 2.75% of their portfolio NEW YORK, NY 200,000200.0k $8.6m $8.6m 2.75% Added +87.6k +87,615
24 MARSHALL WACE, LLP 0.01% of their portfolio LONDON, X0 176,237176.2k $7.5m $7.5m 0.01% New
25 Commodore Capital LP 0.49% of their portfolio NEW YORK, NY 169,533169.5k $7.3m $7.3m 0.49% Reduced -530.5k -530,467
26 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 167,021167.0k $7.2m $7.2m 0.00% Added +4.2k +4,177
27 Altium Capital Management LLC 2.92% of their portfolio NEW YORK, NY 152,909152.9k $6.5m $6.5m 2.92% Added +48.0k +48,000
28 PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio BALTIMORE, MD 152,620152.6k $6.5m $6.5m 0.00% New
29 Balyasny Asset Management L.P. 0.02% of their portfolio Chicago, IL 151,618151.6k $6.5m $6.5m 0.02% Reduced -775.3k -775,258
30 Sofinnova Investments, Inc. 0.38% of their portfolio Menlo Park, CA 150,775150.8k $6.5m $6.5m 0.38% Added +149.6k +149,575
31 BOOTHBAY FUND MANAGEMENT, LLC 0.16% of their portfolio NEW YORK, NY 132,031132.0k $5.7m $5.7m 0.16% Added +8.9k +8,892
32 STEMPOINT CAPITAL LP 1.32% of their portfolio NEW YORK, NY 115,833115.8k $5.0m $5.0m 1.32% New
33 Woodline Partners LP 0.04% of their portfolio San Francisco, CA 106,460106.5k $4.6m $4.6m 0.04% Reduced -93.5k -93,540
34 Rafferty Asset Management, LLC 0.02% of their portfolio New York, NY 106,144106.1k $4.5m $4.5m 0.02% Added +54.3k +54,270
35 Allspring Global Investments Holdings, LLC 0.01% of their portfolio CHARLOTTE, NC 103,839103.8k $4.4m $4.4m 0.01% New
36 SOROS FUND MANAGEMENT LLC 0.10% of their portfolio NEW YORK, NY 100,000100.0k $4.3m $4.3m 0.10% New
37 CITIGROUP INC 0.00% of their portfolio NEW YORK, NY 97,75497.8k $4.2m $4.2m 0.00% Added +63.8k +63,792
38 MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio NEW YORK, NY 92,22592.2k $3.9m $3.9m 0.00% Added +78.5k +78,542
39 Qube Research & Technologies Ltd 0.01% of their portfolio LONDON, X0 78,50078.5k $3.4m $3.4m 0.01% Added +59.8k +59,804
40 683 Capital Management, LLC 0.34% of their portfolio NEW YORK, NY 78,00078.0k $3.3m $3.3m 0.34% Reduced -9.0k -9,000
41 BANK OF AMERICA CORP /DE/ 0.00% of their portfolio CHARLOTTE, NC 72,82672.8k $3.1m $3.1m 0.00% Added +15.4k +15,356
42 Informed Momentum Co LLC 0.43% of their portfolio SOLANA BEACH, CA 64,41164.4k $2.8m $2.8m 0.43% Reduced -29.0k -29,014
43 UBS Group AG 0.00% of their portfolio ZURICH, V8 53,80553.8k $2.3m $2.3m 0.00% Added +36.0k +36,017
44 Schonfeld Strategic Advisors LLC 0.02% of their portfolio NEW YORK, NY 45,47245.5k $1.9m $1.9m 0.02% Reduced -15.4k -15,418
45 Artia Global Partners LP 0.43% of their portfolio MIAMI, FL 40,92440.9k $1.8m $1.8m 0.43% New
46 Caption Management, LLC 0.19% of their portfolio OKLAHOMA CITY, OK 40,00040.0k $1.7m $1.7m 0.19% New
47 Jefferies Financial Group Inc. 0.03% of their portfolio NEW YORK, NY 35,89135.9k $1.5m $1.5m 0.03% Added +800 +800
48 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 33,96834.0k $1.5m $1.5m 0.00% Added +650 +650
49 AMERIPRISE FINANCIAL INC 0.00% of their portfolio MINNEAPOLIS, MN 31,14031.1k $1.3m $1.3m 0.00% New
50 Swiss National Bank 0.00% of their portfolio ZURICH, V8 30,10030.1k $1.3m $1.3m 0.00% Added +7.3k +7,300
51 FARALLON CAPITAL MANAGEMENT, L.L.C. 0.01% of their portfolio SAN FRANCISCO, CA 27,75027.8k $1.2m $1.2m 0.01% Reduced -137.5k -137,469
52 Allianz Asset Management GmbH 0.00% of their portfolio MUNICH, 2M 25,10025.1k $1.1m $1.1m 0.00% New
53 MAPLELANE CAPITAL, LLC 0.07% of their portfolio New York, NY 25,00025.0k $1.1m $1.1m 0.07% Unchanged
54 MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio Toronto, A6 22,38822.4k $958.2k $958.2k 0.00% New
55 ALPS ADVISORS INC 0.01% of their portfolio Denver, CO 21,51421.5k $920.8k $920.8k 0.01% Added +2.0k +2,028
56 TD Asset Management Inc 0.00% of their portfolio Toronto, A6 21,00021.0k $898.8k $898.8k 0.00% New
57 BARCLAYS PLC 0.00% of their portfolio LONDON, X0 20,61920.6k $882.5k $882.5k 0.00% Reduced -686 -686
58 CREDIT SUISSE AG/ 0.00% of their portfolio ZURICH, V8 17,21917.2k $737.0k $737.0k 0.00% Added +4.4k +4,380
59 TUDOR INVESTMENT CORP ET AL 0.01% of their portfolio STAMFORD, CT 16,19416.2k $693.1k $693.1k 0.01% New
60 PROFUND ADVISORS LLC 0.03% of their portfolio BETHESDA, MD 16,07416.1k $688.0k $688.0k 0.03% Added +7.9k +7,887
61 JANE STREET GROUP, LLC 0.00% of their portfolio NEW YORK, NY 14,83814.8k $635.1k $635.1k 0.00% Reduced -30.6k -30,618
62 Squarepoint Ops LLC 0.00% of their portfolio NEW YORK, NY 14,58014.6k $624.0k $624.0k 0.00% Added +7.7k +7,671
63 ExodusPoint Capital Management, LP 0.01% of their portfolio NEW YORK, NY 14,20614.2k $608.0k $608.0k 0.01% New
64 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio WEST SACRAMENTO, CA 13,78013.8k $589.8k $589.8k 0.00% Added +3.5k +3,481
65 SEI INVESTMENTS CO 0.00% of their portfolio OAKS, PA 12,57712.6k $538.3k $538.3k 0.00% Added +2.3k +2,264
66 Legal & General Group Plc 0.00% of their portfolio London, X0 12,28312.3k $525.7k $525.7k 0.00% Added +4.6k +4,556
67 ASPIRIANT, LLC 0.02% of their portfolio San Francisco, CA 12,12812.1k $519.1k $519.1k 0.02% Unchanged
68 Cannon Global Investment Management, LLC 1.36% of their portfolio DAVIE, FL 11,80011.8k $505.0k $505.0k 1.36% New
69 STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio MADISON, WI 11,12611.1k $476.2k $476.2k 0.00% Added +1.6k +1,630
70 HighVista Strategies LLC 0.16% of their portfolio BOSTON, MA 10,42810.4k $446.3k $446.3k 0.16% New
71 SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio BALA CYNWYD, PA 9,0229.0k $386.1k $386.1k 0.00% Reduced -12.6k -12,598
72 UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio NEW YORK, NY 8,8248.8k $377.7k $377.7k 0.00% New
73 VICTORY CAPITAL MANAGEMENT INC 0.00% of their portfolio San Antonio, TX 8,4918.5k $363.4k $363.4k 0.00% New
74 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio SAN FRANCISCO, CA 7,1957.2k $307.9k $307.9k 0.00% Unchanged
75 Polymer Capital Management (HK) LTD 0.07% of their portfolio HONG KONG, K3 6,9146.9k $295.9k $295.9k 0.07% New
76 LMR Partners LLP 0.01% of their portfolio LONDON, X0 6,8306.8k $292.3k $292.3k 0.01% New
77 AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio Greenwich, CT 6,7926.8k $290.7k $290.7k 0.00% New
78 E Fund Management Co., Ltd. 0.01% of their portfolio GUANGZHOU, F4 5,0165.0k $214.7k $214.7k 0.01% New
79 Ensign Peak Advisors, Inc 0.00% of their portfolio SALT LAKE CITY, UT 4,7014.7k $201.2k $201.2k 0.00% New
80 Tower Research Capital LLC (TRC) 0.00% of their portfolio NEW YORK, NY 3,0723.1k $131.5k $131.5k 0.00% Added +2.6k +2,592
81 AlphaQuest LLC 0.02% of their portfolio New York, NY 2,5962.6k $111.1k $111.1k 0.02% New
82 VIRTUS ADVISERS, LLC 0.05% of their portfolio HARTFORD, CT 2,3272.3k $99.6k $99.6k 0.05% Reduced -163 -163
83 Bollard Group LLC 0.00% of their portfolio BOSTON, MA 2,2882.3k $98.0k $98.0k 0.00% Unchanged
84 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 1,8961.9k $81.2k $81.2k 0.00% Added +534 +534
85 SHELL ASSET MANAGEMENT CO 0.00% of their portfolio THE HAGUE, P7 1,8811.9k $77.0k $77.0k 0.00% Reduced -215 -215
86 MACQUARIE GROUP LTD 0.00% of their portfolio Sydney, NSW 2000, C3 1,7361.7k $74 $74 0.00% New
87 Quarry LP 0.03% of their portfolio NEW YORK, NY 1,6501.6k $70.6k $70.6k 0.03% New
88 OSAIC HOLDINGS, INC. 0.00% of their portfolio SCOTTSDALE, AZ 1,0541.1k $45.1k $45.1k 0.00% Added +983 +983
89 WELLS FARGO & COMPANY/MN 0.00% of their portfolio SAN FRANCISCO, CA 564564 $24.1k $24.1k 0.00% Added +449 +449
90 Pacer Advisors, Inc. 0.00% of their portfolio Malvern, PA 491491 $21.0k $21.0k 0.00% New
91 Balefire, LLC 0.00% of their portfolio DALLAS, TX 168168 $7.2k $7.2k 0.00% Unchanged
92 NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio ALBANY, NY 137137 $5.9k $5.9k 0.00% Unchanged
93 EntryPoint Capital, LLC 0.01% of their portfolio NEW YORK, NY 135135 $5.8k $5.8k 0.01% New
94 ROYAL BANK OF CANADA 0.00% of their portfolio TORONTO, A6 9090 $4.0k $4.0k 0.00% New
95 Global Retirement Partners, LLC 0.00% of their portfolio San Rafael, CA 7070 $3.0k $3.0k 0.00% New
96 GROUP ONE TRADING LLC 0.00% of their portfolio CHICAGO, IL 3737 $1.6k $1.6k 0.00% Unchanged
97 HARBOUR INVESTMENTS, INC. 0.00% of their portfolio MADISON, WI 55 $214 $214 0.00% Unchanged
98 CONCOURSE FINANCIAL GROUP SECURITIES, INC. 0.00% of their portfolio BIRMINGHAM, AL 00 $0 $0 0.00% Unchanged
99 NOMURA ASSET MANAGEMENT CO LTD 0.00% of their portfolio TOKYO, M0 00 $0 $0 0.00% New