Vault-13

SCYNEXIS INC SCYX

COM · Common Stock · CUSIP 811292309

39 institutional holders
5,132,2815.1m shares reported held*
51.6% of all shares outstanding*
$20.9mreported value*

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($62.9k this quarter). Holder counts are more reliable. Shares outstanding: 9.9m as of 2026-08-01, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $4.07. Options: 1 managers hold calls ($814 notional), 1 hold puts ($407).

Trends to Q2 2026

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$250$500$750$1kQ3 25 calls: $0Q3 25 puts: $0Q3 25P/C —Q4 25 calls: $0Q4 25 puts: $0Q4 25P/C —Q1 26 calls: $0Q1 26 puts: $0Q1 26P/C —Q2 26 calls: $814Q2 26 puts: $407Q2 26P/C 0.50
Numbers
QuarterCallsPutsP/C
Q3 2025$0$0—
Q4 2025$0$0—
Q1 2026$0$0—
Q2 2026$814$4070.50

Biggest buyers

GREAT POINT PARTNERS LLC New +944,292+944.3k
Squadron Capital Management LLC New +756,884+756.9k
Propel Bio Management, LLC New +543,478+543.5k
ADAGE CAPITAL PARTNERS GP, L.L.C. New +543,478+543.5k
Woodline Partners LP New +387,520+387.5k
VANGUARD CAPITAL MANAGEMENT LLC New +296,747+296.7k
Avidity Partners Management LP New +260,206+260.2k
KINGDON CAPITAL MANAGEMENT, L.L.C. New +247,811+247.8k
MILLENNIUM MANAGEMENT LLC New +180,788+180.8k
HEIGHTS CAPITAL MANAGEMENT, INC New +150,551+150.6k

Biggest sellers

None

Biggest calls

SIMPLEX TRADING, LLC New $814200 shares

Biggest puts

SIMPLEX TRADING, LLC New $407100 shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
GREAT POINT PARTNERS LLC 13G · passive investor filed 2026-08-14 10.0% 4.1m≈ $4.4m 2026-08-14
Adage Capital Management, L.P. 13G · institution new · filed 2026-08-12 10.0% new 1.0m≈ $4.2m 2026-08-12
CVI Investments, Inc. 13G · passive investor filed 2026-08-14 5.9% 615.5k≈ $2.5m 2026-08-14

Insider purchases and sales since 1 Apr 2026

Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.

Officers and directors buying vs selling

Number of people, by quarter (10% owners not included)

BuyingSelling
101Q4 24: 0 buyingQ4 24: 0 sellingQ1 25: 0 buyingQ1 25: 0 sellingQ1 25Q2 25: 0 buyingQ2 25: 0 sellingQ3 25: 0 buyingQ3 25: 0 sellingQ3 25Q4 25: 0 buyingQ4 25: 0 sellingQ1 26: 0 buyingQ1 26: 0 sellingQ1 26Q2 26: 1 buyingQ2 26: 0 sellingQ3 26: 0 buyingQ3 26: 0 sellingQ3 26
Numbers
QuarterBuyingBoughtSellingSoldSold under a plan
Q4 20240—0——
Q1 20250—0——
Q2 20250—0——
Q3 20250—0——
Q4 20250—0——
Q1 20260—0——
Q2 20261—0——
Q3 20260—0——
DateInsiderTradeSharesPrice ValueTheir holding
2026-04-01 Angulo Gonzalez David Chief Executive Officer, director Bought 108,695 — —108.7k shares +9%

Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).

Holders, Q2 2026

#ManagerLocationShares Value% of their portfolioChangeShares change
1 GREAT POINT PARTNERS LLC 0.91% of their portfolio Greenwich, CT 944,292944.3k $3.8m $3.8m 0.91% New
2 Squadron Capital Management LLC 1.05% of their portfolio OAK BROOK, IL 756,884756.9k $3.1m $3.1m 1.05% New
3 ADAGE CAPITAL PARTNERS GP, L.L.C. 0.00% of their portfolio Boston, MA 543,478543.5k $2.2m $2.2m 0.00% New
4 Propel Bio Management, LLC 1.16% of their portfolio Los Angeles, CA 543,478543.5k $2.2m $2.2m 1.16% New
5 Woodline Partners LP 0.00% of their portfolio San Francisco, CA 387,520387.5k $1.6m $1.6m 0.00% New
6 VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio MALVERN, PA 296,747296.7k $1.2m $1.2m 0.00% New
7 Avidity Partners Management LP 0.17% of their portfolio DALLAS, TX 260,206260.2k $1.1m $1.1m 0.17% New
8 KINGDON CAPITAL MANAGEMENT, L.L.C. 0.14% of their portfolio NEW YORK, NY 247,811247.8k $1.0m $1.0m 0.14% New
9 MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio NEW YORK, NY 180,788180.8k $735.8k $735.8k 0.00% New
10 HEIGHTS CAPITAL MANAGEMENT, INC 0.14% of their portfolio SAN FRANCISCO, CA 150,551150.6k $612.7k $612.7k 0.14% New
11 DAFNA Capital Management LLC 0.11% of their portfolio LOS ANGELES, CA 135,868135.9k $553.0k $553.0k 0.11% New
12 Empery Asset Management, LP 0.60% of their portfolio NEW YORK, NY 126,451126.5k $514.7k $514.7k 0.60% New
13 ACADIAN ASSET MANAGEMENT LLC 0.00% of their portfolio Boston, MA 116,669116.7k $473.0k $473.0k 0.00% New
14 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 82,09382.1k $334.2k $334.2k 0.00% New
15 RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio NEW YORK, NY 76,52576.5k $311.5k $311.5k 0.00% New
16 VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio MALVERN, PA 57,97058.0k $235.9k $235.9k 0.00% New
17 ADAR1 Capital Management, LLC 0.01% of their portfolio AUSTIN, TX 49,38749.4k $201.0k $201.0k 0.01% New
18 BlackRock, Inc. 0.00% of their portfolio New York, NY 41,52241.5k $169.0k $169.0k 0.00% New
19 Velan Capital Investment Management LP 0.10% of their portfolio ALPHARETTA, GA 40,00040.0k $162.8k $162.8k 0.10% New
20 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 22,38522.4k $91.1k $91.1k 0.00% New
21 BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.00% of their portfolio HOUSTON, TX 15,55415.6k $63.3k $63.3k 0.00% New
22 Empowered Funds, LLC 0.00% of their portfolio NEWTOWN SQUARE, PA 15,46215.5k $62.9k $62.9k 0.00% New
23 WEALTH EFFECTS LLC 0.02% of their portfolio BOSTON, MA 13,87413.9k $56.5k $56.5k 0.02% New
24 XTX Topco Ltd 0.00% of their portfolio LONDON, X0 12,95913.0k $52.7k $52.7k 0.00% New
25 UBS Group AG 0.00% of their portfolio ZURICH, V8 11,22311.2k $45.7k $45.7k 0.00% New
26 DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio AUSTIN, TX 10,02010.0k $40.8k $40.8k 0.00% New
27 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 4,0934.1k $16.7k $16.7k 0.00% New
28 Vanguard Global Advisers, LLC 0.00% of their portfolio MALVERN, PA 936936 $3.8k $3.8k 0.00% New
29 Tower Research Capital LLC (TRC) 0.00% of their portfolio NEW YORK, NY 650650 $2.6k $2.6k 0.00% New
30 ROYAL BANK OF CANADA 0.00% of their portfolio TORONTO, A6 602602 $2.0k $2.0k 0.00% New
31 SIMPLEX TRADING, LLC 0.00% of their portfolio CHICAGO, IL 391391 $1.6k $1.6k 0.00% New
32 US BANCORP \DE\ 0.00% of their portfolio MINNEAPOLIS, MN 387387 $1.6k $1.6k 0.00% New
33 NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO 0.00% of their portfolio MILWAUKEE, WI 310310 $1.3k $1.3k 0.00% New
34 BARCLAYS PLC 0.00% of their portfolio LONDON, X0 291291 $1.2k $1.2k 0.00% New
35 OSAIC HOLDINGS, INC. 0.00% of their portfolio SCOTTSDALE, AZ 167167 $679 $679 0.00% New
36 HighMark Wealth Management LLC 0.00% of their portfolio ST. PAUL, MN 132132 $537 $537 0.00% New
37 Cornerstone Planning Group LLC 0.00% of their portfolio FAIRFIELD, NJ 3737 $146 $146 0.00% New
38 SBI Securities Co., Ltd. 0.00% of their portfolio TOKYO, M0 2929 $118 $118 0.00% New
39 Bogart Wealth, LLC 0.00% of their portfolio MCLEAN, VA 11 $4 $4 0.00% New