SCHRODINGER INC SDGR
COM · Common Stock · CUSIP 80810D103 · ISIN US80810D1037
American life sciences company
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersNew York, NY
- Founded1990
- Websiteschrodinger.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($45.1m this quarter). Holder counts are more reliable. Implied quarter-end price ≈ $16.25. Options: 8 managers hold calls ($10.7m notional), 8 hold puts ($8.6m).
Trends to Q2 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 198 |
| Q4 2022 | 171 |
| Q1 2023 | 184 |
| Q2 2023 | 241 |
| Q3 2023 | 237 |
| Q4 2023 | 240 |
| Q1 2024 | 224 |
| Q2 2024 | 208 |
| Q3 2024 | 209 |
| Q4 2024 | 213 |
| Q1 2025 | 220 |
| Q2 2025 | 234 |
| Q3 2025 | 225 |
| Q4 2025 | 223 |
| Q1 2026 | 228 |
| Q2 2026 | 231 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2024 | 95 | 104 |
| Q4 2024 | 87 | 105 |
| Q1 2025 | 104 | 89 |
| Q2 2025 | 120 | 106 |
| Q3 2025 | 91 | 128 |
| Q4 2025 | 97 | 109 |
| Q1 2026 | 125 | 98 |
| Q2 2026 | 126 | 102 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2025 | $57.6m | $6.2m | 0.11 |
| Q4 2025 | $65.7m | $7.5m | 0.11 |
| Q1 2026 | $6.4m | $6.9m | 1.08 |
| Q2 2026 | $10.7m | $8.6m | 0.81 |
Biggest buyers
| AQR CAPITAL MANAGEMENT LLC | Added | +1.5m |
| BlackRock, Inc. | Added | +843.2k |
| CITADEL ADVISORS LLC | Added | +698.5k |
| JACOBS LEVY EQUITY MANAGEMENT, INC | New | +523.7k |
| Nuveen, LLC | Added | +488.5k |
| Capricorn Fund Managers Ltd | New | +434.3k |
| Rubric Capital Management LP | Added | +400.0k |
| OP Asset Management Ltd | New | +325.5k |
| JANE STREET GROUP, LLC | New | +218.1k |
| Squarepoint Ops LLC | Added | +155.6k |
Biggest sellers
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | Reduced | -1.8m |
| BAILLIE GIFFORD & CO | Sold out | -801.2k |
| Man Group plc | Sold out | -681.1k |
| Prosight Management, LP | Sold out | -510.6k |
| Sumitomo Mitsui Trust Group, Inc. | Reduced | -484.7k |
| Amova Asset Management Americas, Inc. | Reduced | -484.7k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | Reduced | -438.8k |
| MILLENNIUM MANAGEMENT LLC | Sold out | -416.8k |
| UBS Group AG | Reduced | -355.9k |
| DIMENSIONAL FUND ADVISORS LP | Reduced | -247.3k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $4.9m300.8k shares |
| PEAK6 LLC | Added | $2.2m134.9k shares |
| IMC-Chicago, LLC | Added | $1.2m72.0k shares |
| CITADEL ADVISORS LLC | Reduced | $778.4k47.9k shares |
| SIMPLEX TRADING, LLC | Reduced | $586.6k36.1k shares |
| Walleye Capital LLC | Added | $505.4k31.1k shares |
| JANE STREET GROUP, LLC | Added | $388.4k23.9k shares |
| GROUP ONE TRADING LLC | Reduced | $167.4k10.3k shares |
Biggest puts
| PEAK6 LLC | Unchanged | $3.8m232.3k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $2.2m136.7k shares |
| D. E. Shaw & Co., Inc. | Unchanged | $862.9k53.1k shares |
| IMC-Chicago, LLC | Added | $820.6k50.5k shares |
| CITADEL ADVISORS LLC | Reduced | $667.9k41.1k shares |
| Walleye Capital LLC | Reduced | $118.6k7.3k shares |
| SIMPLEX TRADING, LLC | Added | $94.2k5.8k shares |
| GROUP ONE TRADING LLC | Reduced | $43.9k2.7k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| BlackRock, Inc. 13G · institution filed 2025-07-18 | 12.7% |
| Rubric Capital Management LP 13G · institution +2.8 pts · filed 2026-05-15 | 9.3% |
| VANGUARD PORTFOLIO MANAGEMENT LLC 13G · institution new · filed 2026-04-29 | 6.0% |
Fell to 5% or below in the last year: Sumitomo Mitsui Trust Group, Inc. (4.9%, 2026-04-30), VANGUARD GROUP INC (0.0%, 2026-03-27; now reported by VANGUARD PORTFOLIO MANAGEMENT LLC)
Insider purchases and sales since 1 Apr 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2024 | 0 | — | 1 | $27.2k | $27.2k |
| Q1 2025 | 0 | — | 5 | $339.9k | $220.4k |
| Q2 2025 | 0 | — | 1 | $419.5k | $419.5k |
| Q3 2025 | 0 | — | 0 | — | — |
| Q4 2025 | 0 | — | 1 | $29.4k | $29.4k |
| Q1 2026 | 0 | — | 7 | $293.2k | $293.2k |
| Q2 2026 | 0 | — | 2 | $1.1m | $1.1m |
| Q3 2026 | 0 | — | 2 | $941.6k | $941.6k |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2026-09-17 | Akinsanya Karen Officer | Sold plan | $928.0k31.6k shares |
| 2026-07-16 | Jain Rachit EVP & CFO | Sold plan | $13.7k875 shares |
| 2026-04-17 | Farid Ramy President & CEO, director | Sold plan | $525.0k43.0k shares |
| 2026-04-16 | Farid Ramy President & CEO, director | Sold plan | $530.2k43.0k shares |
| 2026-04-16 | Jain Rachit EVP & CFO | Sold plan | $10.8k844 shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2026
| Manager | Shares | Change |
|---|---|---|
| BlackRock, Inc. 0.00% of their portfolio | 10.5m $171.0m | Added +843.2k |
| GATES FOUNDATION TRUST 0.33% of their portfolio | 7.0m $113.5m | Unchanged |
| Rubric Capital Management LP 0.95% of their portfolio | 6.4m $104.0m | Added +400.0k |
| VANGUARD PORTFOLIO MANAGEMENT LLC 0.00% of their portfolio | 3.8m $61.5m | Reduced -74.8k |
| Sumitomo Mitsui Trust Group, Inc. 0.03% of their portfolio | 2.7m $44.0m | Reduced -484.7k |
| Amova Asset Management Americas, Inc. 0.57% of their portfolio | 2.7m $43.9m | Reduced -484.7k |
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 2.7m $43.7m | Added +86.8k |
| STATE STREET CORP 0.00% of their portfolio | 2.3m $37.3m | Added +106.9k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.01% of their portfolio | 2.2m $36.1m | Reduced -438.8k |
| ARK Investment Management LLC 0.23% of their portfolio | 2.2m $35.0m | Added +86.9k |
| AQR CAPITAL MANAGEMENT LLC 0.01% of their portfolio | 2.0m $31.8m | Added +1.5m |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 1.5m $23.9m | Added +119.7k |
| MORGAN STANLEY 0.00% of their portfolio | 1.2m $20.2m | Reduced -126.2k |
| UBS Group AG 0.00% of their portfolio | 964.1k $15.7m | Reduced -355.9k |
| CITADEL ADVISORS LLC 0.01% of their portfolio | 895.8k $14.6m | Added +698.5k |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ 0.00% of their portfolio | 866.9k $14.1m | Reduced -1.8m |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 732.9k $11.9m | Reduced -19.7k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 649.5k $10.6m | Added +76.4k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 636.4k $10.3m | Reduced -247.3k |
| Nuveen, LLC 0.00% of their portfolio | 614.3k $10.0m | Added +488.5k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 586.8k $9.5m | Added +77.0k |
| JACOBS LEVY EQUITY MANAGEMENT, INC 0.03% of their portfolio | 523.7k $8.5m | New |
| HRT FINANCIAL LP 0.02% of their portfolio | 485.0k $7.9m | Added +2.4k |
| Capricorn Fund Managers Ltd 0.56% of their portfolio | 434.3k $7.1m | New |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 412.2k $6.7m | Added +14.8k |
| TUDOR INVESTMENT CORP ET AL 0.03% of their portfolio | 409.1k $6.6m | Reduced -141.5k |
| ALGERT GLOBAL LLC 0.06% of their portfolio | 328.4k $5.3m | Reduced -147.4k |
| Jump Financial, LLC 0.05% of their portfolio | 326.5k $5.3m | Added +145.2k |
| OP Asset Management Ltd 0.06% of their portfolio | 325.5k $5.3m | New |
| Bank of New York Mellon Corp 0.00% of their portfolio | 306.9k $5.0m | Added +4.9k |
| ExodusPoint Capital Management, LP 0.04% of their portfolio | 296.5k $4.8m | Added +93.1k |
| Tejara Capital Ltd 1.87% of their portfolio | 280.2k $4.6m | Reduced -108.6k |
| PRINCIPAL FINANCIAL GROUP INC 0.00% of their portfolio | 278.9k $4.5m | Added +4.4k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 276.2k $4.8m | Reduced -6.7k |
| LAZARD ASSET MANAGEMENT LLC 0.01% of their portfolio | 231.0k $3.8m | Added +18.5k |
| Invesco Ltd. 0.00% of their portfolio | 230.2k $3.7m | Added +21.3k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 218.1k $3.5m | New |
| Susquehanna Portfolio Strategies, LLC 0.06% of their portfolio | 214.4k $3.5m | Added +15.4k |
| Squarepoint Ops LLC 0.01% of their portfolio | 209.1k $3.4m | Added +155.6k |
| Universal- Beteiligungs- und Servicegesellschaft mbH 0.01% of their portfolio | 208.6k $3.4m | Added +101.8k |
| CAPITAL FUND MANAGEMENT S.A. 0.02% of their portfolio | 202.3k $3.3m | Added +82.2k |
| Public Sector Pension Investment Board 0.01% of their portfolio | 195.9k $3.2m | Reduced -4.8k |
| Connor, Clark & Lunn Investment Management Ltd. 0.01% of their portfolio | 195.7k $3.2m | Reduced -115.0k |
| Zurcher Kantonalbank (Zurich Cantonalbank) 0.01% of their portfolio | 183.5k $3.0m | Reduced -37.8k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 180.7k $2.9m | Added +34.8k |
| Legal & General Group Plc 0.00% of their portfolio | 140.9k $2.3m | Added +4.3k |
| Schonfeld Strategic Advisors LLC 0.01% of their portfolio | 137.4k $2.2m | Added +52.6k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 136.4k $2.2m | Reduced -23.1k |
| Quantinno Capital Management LP 0.00% of their portfolio | 135.0k $2.2m | Reduced -39.1k |
| Trexquant Investment LP 0.01% of their portfolio | 134.2k $2.2m | Added +84.7k |
| Swiss National Bank 0.00% of their portfolio | 127.2k $2.1m | Unchanged |
| Mariner, LLC 0.00% of their portfolio | 117.9k $1.9m | Added +100.9k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 109.0k $1.8m | Added +28.3k |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 106.2k $1.7m | Reduced -14.7k |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 97.9k $1.6m | Added +62.8k |
| IQ EQ FUND MANAGEMENT (IRELAND) Ltd 0.09% of their portfolio | 87.0k $1.4m | Added +7.9k |
| XTX Topco Ltd 0.02% of their portfolio | 86.7k $1.4m | Added +7.0k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 83.8k $1.4m | Reduced -37.9k |
| WESBANCO BANK INC 0.03% of their portfolio | 81.4k $1.3m | Unchanged |
| SummitTX Capital, L.P. 0.03% of their portfolio | 75.6k $1.2m | New |
| Creative Planning 0.00% of their portfolio | 75.2k $1.2m | Added +30.7k |
| NANO CAP NEW MILLENNIUM GROWTH FUND L P 0.94% of their portfolio | 75.0k $1.2m | Added +25.0k |
| TrueMark Investments, LLC 0.15% of their portfolio | 73.2k $1.2m | Added +27.5k |
| Quadrature Capital Ltd 0.01% of their portfolio | 72.6k $1.2m | Added +55.7k |
| IEQ CAPITAL, LLC 0.01% of their portfolio | 71.4k $1.2m | New |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 68.6k $1.1m | Added +18.6k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 68.4k $777.0k | Unchanged |
| LPL Financial LLC 0.00% of their portfolio | 67.4k $1.1m | Added +12.0k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 67.3k $1.1m | Added +6.1k |
| MERCER GLOBAL ADVISORS INC /ADV 0.00% of their portfolio | 65.3k $1.1m | Added +46.7k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 62.4k $1.0m | Added +10.4k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 62.2k $1.0m | Added +33.0k |
| PRUDENTIAL FINANCIAL INC 0.00% of their portfolio | 58.8k $954.9k | Added +870 |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC 0.00% of their portfolio | 54.4k $897.1k | Added +41.3k |
| ANTIPODES PARTNERS Ltd 0.02% of their portfolio | 53.0k $860.8k | Reduced -4.0k |
| BARCLAYS PLC 0.00% of their portfolio | 52.0k $845.3k | Added +11.1k |
| Beacon Pointe Advisors, LLC 0.00% of their portfolio | 51.6k $839.3k | Added +43 |
| Kestra Advisory Services, LLC 0.00% of their portfolio | 50.7k $824.3k | Reduced -703 |
| MYDA Advisors LLC 0.20% of their portfolio | 50.0k $812.5k | New |
| Cerity Partners LLC 0.00% of their portfolio | 48.8k $792.5k | New |
| Engineers Gate Manager LP 0.01% of their portfolio | 48.1k $782.4k | Reduced -71.2k |
| NEW YORK STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 45.9k $746.0k | Added +1.9k |
| PEAK6 LLC 0.02% of their portfolio | 44.5k $722.4k | Reduced -28.5k |
| EntryPoint Capital, LLC 0.17% of their portfolio | 44.0k $714.9k | Reduced -94.6k |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 43.0k $699.1k | Reduced -3.8k |
| J. Safra Sarasin Holding AG 0.01% of their portfolio | 42.3k $687.0k | New |
| Atom Investors LP 0.06% of their portfolio | 41.7k $677.4k | Reduced -81.3k |
| CITIGROUP INC 0.00% of their portfolio | 41.6k $676.0k | Reduced -4.1k |
| CANADA LIFE ASSURANCE Co 0.00% of their portfolio | 41.6k $675.0k | Reduced -13.0k |
| Palumbo Wealth Management LLC 0.14% of their portfolio | 40.8k $662.4k | New |
| VANGUARD ASSET MANAGEMENT, Ltd 0.00% of their portfolio | 40.7k $661.2k | Unchanged |
| Thrivent Financial for Lutherans 0.00% of their portfolio | 37.5k $609.0k | Reduced -3 |
| MetLife Investment Management, LLC 0.00% of their portfolio | 33.9k $551.6k | Added +1.3k |
| Eurizon Capital SGR S.p.A. 0.00% of their portfolio | 33.9k $551.1k | Added +7.6k |
| SEI INVESTMENTS CO 0.00% of their portfolio | 33.0k $536.4k | New |
| Focus Partners Wealth 0.00% of their portfolio | 32.6k $529.6k | Added +18.1k |
| PIER 88 INVESTMENT PARTNERS LLC 0.12% of their portfolio | 31.4k $510.2k | Reduced -14.7k |
| TOCQUEVILLE ASSET MANAGEMENT L.P. 0.01% of their portfolio | 30.9k $502.1k | Added +6.3k |
| ROYCE & ASSOCIATES LP 0.00% of their portfolio | 29.0k $471.4k | Unchanged |
| BRANDYWINE MANAGERS, LLC 0.23% of their portfolio | 28.5k $462.4k | Unchanged |