SAREPTA THERAPEUTICS INC SRPT
COM · Common Stock · CUSIP 803607100 · ISIN US8036071004
Biopharmaceutical company
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersCambridge, MA
- Founded1980
- Websitesarepta.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($8.3m this quarter). Holder counts are more reliable. Shares outstanding: 94.5m as of 2024-04-26, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $129.41. Options: 30 managers hold calls ($656.0m notional), 22 hold puts ($204.9m).
Trends to Q1 2024
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 376 |
| Q4 2022 | 414 |
| Q1 2023 | 427 |
| Q2 2023 | 406 |
| Q3 2023 | 396 |
| Q4 2023 | 397 |
| Q1 2024 | 416 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 199 | 169 |
| Q1 2023 | 219 | 183 |
| Q2 2023 | 204 | 205 |
| Q3 2023 | 201 | 180 |
| Q4 2023 | 181 | 206 |
| Q1 2024 | 215 | 178 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q2 2023 | $276.3m | $402.2m | 1.46 |
| Q3 2023 | $655.9m | $524.1m | 0.80 |
| Q4 2023 | $715.7m | $383.4m | 0.54 |
| Q1 2024 | $656.0m | $204.9m | 0.31 |
Biggest buyers
| FARALLON CAPITAL MANAGEMENT, L.L.C. | Added | +1.2m |
| EcoR1 Capital, LLC | Added | +1.1m |
| Paradigm Biocapital Advisors LP | New | +1.1m |
| JPMORGAN CHASE & CO | Added | +1.1m |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | New | +470.0k |
| Logos Global Management LP | New | +400.0k |
| CANADA PENSION PLAN INVESTMENT BOARD | Added | +230.3k |
| MILLENNIUM MANAGEMENT LLC | Added | +230.0k |
| Sofinnova Investments, Inc. | New | +227.5k |
| Cutter Capital Management, LP | New | +188.8k |
Biggest sellers
| WELLINGTON MANAGEMENT GROUP LLP | Reduced | -881.8k |
| BANK OF AMERICA CORP /DE/ | Reduced | -558.9k |
| Deep Track Capital, LP | Sold out | -500.0k |
| JANUS HENDERSON GROUP PLC | Reduced | -454.4k |
| FIRST TRUST ADVISORS LP | Sold out | -432.4k |
| ROYAL BANK OF CANADA | Reduced | -353.4k |
| STATE STREET CORP | Reduced | -276.6k |
| D. E. Shaw & Co., Inc. | Reduced | -268.7k |
| Bank of New York Mellon Corp | Reduced | -262.5k |
| BlackRock Inc. | Reduced | -251.4k |
Biggest calls
| Logos Global Management LP | Added | $155.4m1.2m shares |
| Caption Management, LLC | Reduced | $101.4m783.0k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $92.3m712.6k shares |
| Skaana Management L.P. | Added | $67.2m5.1k shares |
| BOOTHBAY FUND MANAGEMENT, LLC | Reduced | $43.0m332.5k shares |
| CITADEL ADVISORS LLC | Reduced | $42.9m331.1k shares |
| SIMPLEX TRADING, LLC | Reduced | $23.8m184.2k shares |
| GROUP ONE TRADING LLC | Reduced | $22.8m175.8k shares |
| Ikarian Capital, LLC | Reduced | $15.0m116.1k shares |
| LMR Partners LLP | Reduced | $13.3m102.9k shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $43.5m335.9k shares |
| CITADEL ADVISORS LLC | Reduced | $36.1m279.1k shares |
| JANE STREET GROUP, LLC | Reduced | $18.1m139.6k shares |
| LMR Partners LLP | Reduced | $17.4m134.4k shares |
| GROUP ONE TRADING LLC | Reduced | $17.0m131.5k shares |
| SIMPLEX TRADING, LLC | Reduced | $14.8m114.0k shares |
| JPMORGAN CHASE & CO | Reduced | $14.2m110.0k shares |
| Caption Management, LLC | Reduced | $10.3m79.8k shares |
| GTS SECURITIES LLC | Reduced | $9.3m72.1k shares |
| PEAK6 Investments LLC | Reduced | $5.3m40.8k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| BlackRock, Inc. 13G · institution +3.2 pts · filed 2026-07-30 | 15.8% |
| STATE STREET CORP 13G · institution +3.0 pts · filed 2026-08-07 | 8.4% |
| VANGUARD PORTFOLIO MANAGEMENT LLC 13G · institution +1.6 pts · filed 2026-07-31 | 8.1% |
| VANGUARD CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-04-30 | 5.1% |
| AQR CAPITAL MANAGEMENT LLC 13G · institution -2.7 pts · filed 2026-08-13 | 5.0% |
Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-27; now reported by VANGUARD PORTFOLIO MANAGEMENT LLC), D. E. SHAW & CO, L.P. (1.9%, 2025-11-14)
Insider purchases and sales in Q1 2024
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q2 2022 | 0 | — | 0 | — | — |
| Q3 2022 | 1 | $11.0m | 0 | — | — |
| Q4 2022 | 0 | — | 1 | $94.3k | — |
| Q1 2023 | 0 | — | 0 | — | — |
| Q2 2023 | 0 | — | 0 | — | — |
| Q3 2023 | 1 | $7.4m | 1 | $1.6m | — |
| Q4 2023 | 2 | $5.9m | 0 | — | — |
| Q1 2024 | 0 | — | 6 | $3.0m | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2024-03-11 | Boor Kathryn Jean Director | Sold | $93.5k761 shares |
| 2024-03-08 | Wigzell Hans Lennart Rudolf Director | Sold | $1.8m15.0k shares |
| 2024-03-05 | Mayo Stephen Director | Sold | $385.5k3.1k shares |
| 2024-03-01 | Arif Bilal Chief Tech Ops Officer | Sold | $257.7k2.0k shares |
| 2024-03-01 | Brown Ryan Edward EVP, General Counsel | Sold | $250.7k2.0k shares |
| 2024-03-01 | Estepan Ian Michael Chief Financial Officer | Sold | $154.0k1.2k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q1 2024
| Manager | Shares | Change |
|---|---|---|
| VANGUARD GROUP INC 0.02% of their portfolio | 8.8m $1.1bn | Reduced -20.4k |
| BlackRock Inc. 0.02% of their portfolio | 6.0m $771.6m | Reduced -251.4k |
| JANUS HENDERSON GROUP PLC 0.35% of their portfolio | 4.9m $633.2m | Reduced -454.4k |
| Capital International Investors 0.13% of their portfolio | 4.8m $623.7m | Added +76.0k |
| Avoro Capital Advisors LLC 6.56% of their portfolio | 4.3m $562.4m | Unchanged |
| JPMORGAN CHASE & CO 0.02% of their portfolio | 3.7m $473.5m | Added +1.1m |
| WELLINGTON MANAGEMENT GROUP LLP 0.07% of their portfolio | 3.2m $420.2m | Reduced -881.8k |
| MORGAN STANLEY 0.01% of their portfolio | 2.7m $345.1m | Reduced -95.0k |
| FARALLON CAPITAL MANAGEMENT, L.L.C. 1.87% of their portfolio | 2.5m $317.6m | Added +1.2m |
| STATE STREET CORP 0.01% of their portfolio | 2.1m $274.8m | Reduced -276.6k |
| Bank of New York Mellon Corp 0.05% of their portfolio | 2.1m $267.6m | Reduced -262.5k |
| T. Rowe Price Investment Management, Inc. 0.15% of their portfolio | 1.9m $250.1m | Added +11.8k |
| EcoR1 Capital, LLC 6.31% of their portfolio | 1.9m $248.5m | Added +1.1m |
| CITADEL ADVISORS LLC 0.19% of their portfolio | 1.5m $197.2m | Added +180.3k |
| GEODE CAPITAL MANAGEMENT, LLC 0.02% of their portfolio | 1.5m $196.9m | Added +50.8k |
| DEUTSCHE BANK AG\ 0.09% of their portfolio | 1.5m $189.1m | Reduced -14.5k |
| FMR LLC 0.01% of their portfolio | 1.3m $174.6m | Reduced -158.5k |
| Pictet Asset Management Holding SA 0.18% of their portfolio | 1.3m $163.1m | Added +166.9k |
| Paradigm Biocapital Advisors LP 4.91% of their portfolio | 1.1m $139.6m | New |
| Casdin Capital, LLC 10.30% of their portfolio | 1.1m $138.4m | Added +62.5k |
| NORGES BANK 0.02% of their portfolio | 968.8k $125.4m | Added +131.9k |
| MILLENNIUM MANAGEMENT LLC 0.10% of their portfolio | 874.1k $113.2m | Added +230.0k |
| ORBIMED ADVISORS LLC 1.66% of their portfolio | 697.5k $90.3m | Unchanged |
| TWO SIGMA ADVISERS, LP 0.20% of their portfolio | 661.3k $85.6m | Reduced -44.8k |
| BANK OF AMERICA CORP /DE/ 0.01% of their portfolio | 653.5k $84.6m | Reduced -558.9k |
| Boxer Capital, LLC 4.16% of their portfolio | 650.0k $84.1m | Unchanged |
| FEDERATED HERMES, INC. 0.18% of their portfolio | 610.2k $79.0m | Reduced -98.2k |
| Thrivent Financial for Lutherans 0.16% of their portfolio | 606.7k $78.5m | Reduced -222.0k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.02% of their portfolio | 589.4k $76.3m | Added +13.0k |
| Camber Capital Management LP 2.65% of their portfolio | 585.0k $75.7m | Reduced -215.0k |
| JACOBS LEVY EQUITY MANAGEMENT, INC 0.34% of their portfolio | 579.6k $75.0m | Added +120.5k |
| Erste Asset Management GmbH 1.01% of their portfolio | 571.4k $74.0m | Reduced -130.0k |
| Nuveen Asset Management, LLC 0.02% of their portfolio | 542.6k $70.2m | Added +9.3k |
| PERCEPTIVE ADVISORS LLC 1.20% of their portfolio | 525.7k $68.1m | Added +73.8k |
| Balyasny Asset Management L.P. 0.17% of their portfolio | 509.2k $65.9m | Added +10.4k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.01% of their portfolio | 505.0k $65.4m | Reduced -234.8k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.11% of their portfolio | 470.0k $60.8m | New |
| ROYAL BANK OF CANADA 0.01% of their portfolio | 460.6k $59.6m | Reduced -353.4k |
| ALKEON CAPITAL MANAGEMENT LLC 0.33% of their portfolio | 458.8k $59.4m | Added +100.0k |
| Assenagon Asset Management S.A. 0.15% of their portfolio | 437.7k $56.7m | Added +53.9k |
| NORTHERN TRUST CORP 0.01% of their portfolio | 430.8k $55.8m | Reduced -6.7k |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC 0.20% of their portfolio | 430.5k $55.7m | Added +71.9k |
| BANK OF NOVA SCOTIA 0.11% of their portfolio | 421.5k $54.6m | Reduced -107.3k |
| Logos Global Management LP 5.45% of their portfolio | 400.0k $51.8m | New |
| Amundi 0.02% of their portfolio | 398.3k $46.4m | Reduced -1.1k |
| RENAISSANCE TECHNOLOGIES LLC 0.08% of their portfolio | 390.3k $50.5m | Reduced -172.7k |
| BARCLAYS PLC 0.02% of their portfolio | 385.5k $49.9m | Reduced -57.4k |
| Fiera Capital Corp 0.14% of their portfolio | 367.0k $47.5m | Added +18.8k |
| TWO SIGMA INVESTMENTS, LP 0.11% of their portfolio | 342.7k $44.4m | Added +40.3k |
| VOYA INVESTMENT MANAGEMENT LLC 0.04% of their portfolio | 337.6k $43.7m | Added +35.9k |
| Rock Springs Capital Management LP 1.08% of their portfolio | 327.6k $42.4m | Unchanged |
| ALLIANCEBERNSTEIN L.P. 0.01% of their portfolio | 318.2k $41.2m | Added +62.3k |
| MIZUHO MARKETS AMERICAS LLC 1.03% of their portfolio | 290.8k $37.6m | Reduced -14.8k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.05% of their portfolio | 281.7k $36.5m | Added +156.1k |
| JANE STREET GROUP, LLC 0.05% of their portfolio | 278.1k $36.0m | Added +95.5k |
| UBS Group AG 0.01% of their portfolio | 277.2k $35.9m | Added +914 |
| Allspring Global Investments Holdings, LLC 0.05% of their portfolio | 261.3k $33.8m | Reduced -12.4k |
| FRED ALGER MANAGEMENT, LLC 0.17% of their portfolio | 257.6k $33.3m | Added +167.2k |
| Bellevue Group AG 0.50% of their portfolio | 251.5k $32.6m | Added +14.2k |
| GOLDMAN SACHS GROUP INC 0.01% of their portfolio | 250.0k $32.4m | Added +65.2k |
| CANADA PENSION PLAN INVESTMENT BOARD 0.03% of their portfolio | 240.5k $31.1m | Added +230.3k |
| FRANKLIN RESOURCES INC 0.01% of their portfolio | 233.3k $30.2m | Added +19.0k |
| AMERIPRISE FINANCIAL INC 0.01% of their portfolio | 230.8k $29.9m | Reduced -194 |
| Sofinnova Investments, Inc. 1.74% of their portfolio | 227.5k $29.5m | New |
| BNP PARIBAS FINANCIAL MARKETS 0.04% of their portfolio | 225.4k $29.2m | Added +77.0k |
| DIMENSIONAL FUND ADVISORS LP 0.01% of their portfolio | 224.3k $29.0m | Added +90 |
| First Turn Management, LLC 4.29% of their portfolio | 221.7k $28.7m | Added +17.9k |
| EAGLE ASSET MANAGEMENT INC 0.14% of their portfolio | 213.4k $27.4m | Reduced -2.7k |
| Palo Alto Investors LP 2.94% of their portfolio | 201.3k $26.1m | Added +360 |
| Aberdeen Group plc 0.05% of their portfolio | 191.9k $24.8m | Added +45.0k |
| Cutter Capital Management, LP 4.71% of their portfolio | 188.8k $24.4m | New |
| Ensign Peak Advisors, Inc 0.04% of their portfolio | 187.2k $24.2m | Reduced -7.2k |
| BANK OF MONTREAL /CAN/ 0.01% of their portfolio | 176.8k $23.1m | Added +24.3k |
| TD Asset Management Inc 0.02% of their portfolio | 176.6k $22.9m | Reduced -30.5k |
| CREDIT SUISSE AG/ 0.02% of their portfolio | 176.1k $22.8m | Added +8.4k |
| Swiss National Bank 0.02% of their portfolio | 166.2k $21.5m | Added +9.9k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.01% of their portfolio | 161.0k $20.8m | Added +15 |
| NEW YORK STATE COMMON RETIREMENT FUND 0.03% of their portfolio | 160.6k $20.8m | Reduced -10.9k |
| Finepoint Capital LP 5.26% of their portfolio | 158.5k $20.5m | Added +13.1k |
| Ikarian Capital, LLC 5.36% of their portfolio | 152.3k $19.7m | Added +19.6k |
| Clearbridge Investments, LLC 0.02% of their portfolio | 151.2k $19.6m | Added +89 |
| Candriam S.C.A. 0.13% of their portfolio | 151.0k $19.5m | Reduced -31.4k |
| Caption Management, LLC 2.14% of their portfolio | 150.3k $19.5m | Added +150.0k |
| C WorldWide Group Holding A/S 0.21% of their portfolio | 140.3k $18.2m | Unchanged |
| EVENTIDE ASSET MANAGEMENT, LLC 0.28% of their portfolio | 135.5k $17.5m | Added +46.2k |
| GREAT LAKES ADVISORS, LLC 0.15% of their portfolio | 133.1k $17.2m | New |
| Russell Investments Group, Ltd. 0.03% of their portfolio | 127.4k $16.5m | Added +4.2k |
| Ghost Tree Capital, LLC 5.20% of their portfolio | 125.0k $16.2m | Added +25.0k |
| California Public Employees Retirement System 0.01% of their portfolio | 123.8k $16.0m | Reduced -2.6k |
| Man Group plc 0.04% of their portfolio | 120.0k $15.5m | New |
| TOBAM 1.39% of their portfolio | 119.9k $15.5m | Reduced -36.1k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 119.5k $15.5m | Reduced -4.7k |
| RHUMBLINE ADVISERS 0.01% of their portfolio | 110.0k $14.2m | Reduced -8.5k |
| ExodusPoint Capital Management, LP 0.17% of their portfolio | 105.2k $13.6m | Added +97.6k |
| Invesco Ltd. 0.00% of their portfolio | 105.0k $13.6m | Added +36.3k |
| Eagle Health Investments LP 2.55% of their portfolio | 103.3k $13.4m | Reduced -86.1k |
| Vestal Point Capital, LP 1.07% of their portfolio | 100.0k $12.9m | New |
| Cubist Systematic Strategies, LLC 0.14% of their portfolio | 93.6k $12.1m | Added +48.6k |
| Mirae Asset Global Investments Co., Ltd. 0.03% of their portfolio | 90.9k $12.1m | Added +47.9k |
| Simplify Asset Management Inc. 1.12% of their portfolio | 90.5k $11.7m | Added +66.8k |