SAREPTA THERAPEUTICS INC SRPT
COM · Common Stock · CUSIP 803607100 · ISIN US8036071004
Biopharmaceutical company
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersCambridge, MA
- Founded1980
- Websitesarepta.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($37.7m this quarter). Holder counts are more reliable. Shares outstanding: 87.8m as of 2022-10-28, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $110.54. Options: 28 managers hold calls ($269.5m notional), 22 hold puts ($160.2m).
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | — | $37.3m337.8k shares |
| CITADEL ADVISORS LLC | — | $37.0m334.8k shares |
| GROUP ONE TRADING LLC | — | $32.7m296.2k shares |
| PURA VIDA INVESTMENTS, LLC | — | $22.1m200.0k shares |
| JANE STREET GROUP, LLC | — | $21.0m189.9k shares |
| Caption Management, LLC | — | $19.6m177.4k shares |
| PEAK6 Investments LLC | — | $18.7m169.4k shares |
| SIMPLEX TRADING, LLC | — | $9.7m88.1k shares |
| Ikarian Capital, LLC | — | $9.4m85.2k shares |
| Jefferies Group LLC | — | $7.2m65.5k shares |
Biggest puts
| Balyasny Asset Management L.P. | — | $42.0m379.6k shares |
| Caption Management, LLC | — | $26.3m238.2k shares |
| WOLVERINE ASSET MANAGEMENT LLC | — | $12.9m116.8k shares |
| Jefferies Group LLC | — | $12.7m115.0k shares |
| CAAS CAPITAL MANAGEMENT LP | — | $10.2m92.0k shares |
| Walleye Trading LLC | — | $9.5m85.6k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | — | $9.4m84.6k shares |
| CITADEL ADVISORS LLC | — | $9.0m81.6k shares |
| GROUP ONE TRADING LLC | — | $8.1m73.5k shares |
| JANE STREET GROUP, LLC | — | $5.3m48.3k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| BlackRock, Inc. 13G · institution +3.2 pts · filed 2026-07-30 | 15.8% |
| STATE STREET CORP 13G · institution +3.0 pts · filed 2026-08-07 | 8.4% |
| VANGUARD PORTFOLIO MANAGEMENT LLC 13G · institution +1.6 pts · filed 2026-07-31 | 8.1% |
| VANGUARD CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-04-30 | 5.1% |
| AQR CAPITAL MANAGEMENT LLC 13G · institution -2.7 pts · filed 2026-08-13 | 5.0% |
Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-27; now reported by VANGUARD PORTFOLIO MANAGEMENT LLC), D. E. SHAW & CO, L.P. (1.9%, 2025-11-14)
Insider purchases and sales in Q3 2022
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2020 | 0 | — | 0 | — | — |
| Q1 2021 | 0 | — | 0 | — | — |
| Q2 2021 | 0 | — | 0 | — | — |
| Q3 2021 | 0 | — | 0 | — | — |
| Q4 2021 | 2 | $2.3m | 0 | — | — |
| Q1 2022 | 0 | — | 0 | — | — |
| Q2 2022 | 0 | — | 0 | — | — |
| Q3 2022 | 1 | $11.0m | 0 | — | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2022-09-14 | Chambers Michael Andrew Director | Bought | $6.0m57.1k shares |
| 2022-08-19 | Chambers Michael Andrew Director | Bought | $5.0m46.2k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q3 2022
| Manager | Shares | Change |
|---|---|---|
| JANUS HENDERSON GROUP PLC 0.54% of their portfolio | 13.0m $1.4bn | — |
| VANGUARD GROUP INC 0.03% of their portfolio | 8.1m $893.8m | — |
| BlackRock Inc. 0.02% of their portfolio | 5.3m $590.0m | — |
| Avoro Capital Advisors LLC 6.48% of their portfolio | 3.2m $351.0m | — |
| EcoR1 Capital, LLC 9.79% of their portfolio | 3.0m $331.6m | — |
| WELLINGTON MANAGEMENT GROUP LLP 0.06% of their portfolio | 2.6m $282.9m | — |
| FMR LLC 0.03% of their portfolio | 2.5m $281.9m | — |
| SANDS CAPITAL MANAGEMENT, LLC 1.03% of their portfolio | 2.5m $274.4m | — |
| STATE STREET CORP 0.01% of their portfolio | 1.9m $213.9m | — |
| Bank of New York Mellon Corp 0.05% of their portfolio | 1.9m $208.1m | — |
| Camber Capital Management LP 5.55% of their portfolio | 1.5m $165.8m | — |
| ALKEON CAPITAL MANAGEMENT LLC 0.94% of their portfolio | 1.2m $136.1m | — |
| Casdin Capital, LLC 8.94% of their portfolio | 1.2m $135.4m | — |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.02% of their portfolio | 1.2m $134.7m | — |
| GEODE CAPITAL MANAGEMENT, LLC 0.02% of their portfolio | 1.2m $127.6m | — |
| GOLDMAN SACHS GROUP INC 0.04% of their portfolio | 1.1m $125.7m | — |
| Assenagon Asset Management S.A. 0.53% of their portfolio | 1.1m $124.8m | — |
| LORD, ABBETT & CO. LLC 0.43% of their portfolio | 1.1m $117.6m | — |
| AMERICAN CENTURY COMPANIES INC 0.09% of their portfolio | 966.7k $106.9m | — |
| Avidity Partners Management LP 2.28% of their portfolio | 948.2k $104.8m | — |
| ORBIMED ADVISORS LLC 1.89% of their portfolio | 918.5k $101.5m | — |
| FIRST TRUST ADVISORS LP 0.13% of their portfolio | 917.2k $101.4m | — |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.24% of their portfolio | 885.0k $97.8m | — |
| RENAISSANCE TECHNOLOGIES LLC 0.14% of their portfolio | 884.2k $97.7m | — |
| Point72 Asset Management, L.P. 0.41% of their portfolio | 851.9k $94.2m | — |
| NORGES BANK 0.02% of their portfolio | 836.3k $92.4m | — |
| TWO SIGMA INVESTMENTS, LP 0.30% of their portfolio | 789.7k $87.3m | — |
| AMERIPRISE FINANCIAL INC 0.03% of their portfolio | 775.3k $85.7m | — |
| FEDERATED HERMES, INC. 0.25% of their portfolio | 774.9k $85.7m | — |
| Bellevue Group AG 1.20% of their portfolio | 755.9k $83.6m | — |
| FARALLON CAPITAL MANAGEMENT, L.L.C. 0.51% of their portfolio | 755.0k $83.5m | — |
| DEUTSCHE BANK AG\ 0.05% of their portfolio | 747.1k $82.6m | — |
| JPMORGAN CHASE & CO 0.01% of their portfolio | 721.0k $79.7m | — |
| MILLENNIUM MANAGEMENT LLC 0.10% of their portfolio | 712.7k $78.8m | — |
| Thrivent Financial for Lutherans 0.21% of their portfolio | 699.5k $77.3m | — |
| Erste Asset Management GmbH 1.66% of their portfolio | 671.9k $74.2m | — |
| PICTET ASSET MANAGEMENT SA 0.11% of their portfolio | 667.0k $73.7m | — |
| D. E. Shaw & Co., Inc. 0.12% of their portfolio | 632.9k $70.0m | — |
| WESTFIELD CAPITAL MANAGEMENT CO LP 0.52% of their portfolio | 594.8k $65.8m | — |
| TWO SIGMA ADVISERS, LP 0.17% of their portfolio | 534.4k $59.1m | — |
| JACOBS LEVY EQUITY MANAGEMENT, INC 0.44% of their portfolio | 502.2k $55.5m | — |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.02% of their portfolio | 494.6k $54.7m | — |
| Rock Springs Capital Management LP 1.23% of their portfolio | 430.0k $47.5m | — |
| MORGAN STANLEY 0.01% of their portfolio | 396.3k $43.8m | — |
| NORTHERN TRUST CORP 0.01% of their portfolio | 385.6k $42.6m | — |
| BANK OF AMERICA CORP /DE/ 0.01% of their portfolio | 385.0k $42.6m | — |
| Balyasny Asset Management L.P. 0.16% of their portfolio | 368.9k $40.8m | — |
| Logos Global Management LP 4.77% of their portfolio | 350.0k $38.7m | — |
| Nuveen Asset Management, LLC 0.01% of their portfolio | 326.9k $36.1m | — |
| CREDIT SUISSE AG/ 0.04% of their portfolio | 287.2k $31.8m | — |
| FRONTIER CAPITAL MANAGEMENT CO LLC 0.37% of their portfolio | 283.9k $31.4m | — |
| Allspring Global Investments Holdings, LLC 0.05% of their portfolio | 264.7k $29.3m | — |
| PERCEPTIVE ADVISORS LLC 0.81% of their portfolio | 253.0k $28.0m | — |
| Cubist Systematic Strategies, LLC 0.17% of their portfolio | 201.9k $22.3m | — |
| Boxer Capital, LLC 1.24% of their portfolio | 200.0k $22.1m | — |
| Cormorant Asset Management, LP 1.56% of their portfolio | 200.0k $22.1m | — |
| Swiss National Bank 0.02% of their portfolio | 197.1k $21.8m | — |
| VICTORY CAPITAL MANAGEMENT INC 0.03% of their portfolio | 196.5k $21.7m | — |
| AXA S.A. 0.04% of their portfolio | 196.2k $21.7m | — |
| California Public Employees Retirement System 0.02% of their portfolio | 191.3k $21.1m | — |
| DIMENSIONAL FUND ADVISORS LP 0.01% of their portfolio | 189.1k $20.9m | — |
| MOORE CAPITAL MANAGEMENT, LP 0.55% of their portfolio | 180.1k $19.9m | — |
| Invesco Ltd. 0.01% of their portfolio | 173.8k $19.2m | — |
| Hudson Bay Capital Management LP 0.20% of their portfolio | 170.0k $18.8m | — |
| Tekla Capital Management LLC 0.75% of their portfolio | 166.0k $18.3m | — |
| Connor, Clark & Lunn Investment Management Ltd. 0.11% of their portfolio | 157.7k $17.4m | — |
| Iron Triangle Partners LP 2.90% of their portfolio | 150.0k $16.6m | — |
| Russell Investments Group, Ltd. 0.04% of their portfolio | 145.7k $16.1m | — |
| Squarepoint Ops LLC 0.14% of their portfolio | 142.1k $15.7m | — |
| Sofinnova Investments, Inc. 0.99% of their portfolio | 141.4k $15.6m | — |
| ALLIANCEBERNSTEIN L.P. 0.01% of their portfolio | 139.6k $15.4m | — |
| NATIXIS 0.07% of their portfolio | 137.6k $15.2m | — |
| Ensign Peak Advisors, Inc 0.04% of their portfolio | 130.6k $14.4m | — |
| CIBC Asset Management Inc 0.06% of their portfolio | 127.0k $14.0m | — |
| Mirae Asset Global Investments Co., Ltd. 0.04% of their portfolio | 125.5k $13.9m | — |
| C WorldWide Group Holding A/S 0.18% of their portfolio | 120.3k $13.3m | — |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.01% of their portfolio | 120.1k $13.3m | — |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 115.0k $12.7m | — |
| Ghost Tree Capital, LLC 4.96% of their portfolio | 110.0k $12.2m | — |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.02% of their portfolio | 109.5k $12.1m | — |
| PUTNAM INVESTMENTS LLC 0.02% of their portfolio | 107.3k $11.9m | — |
| CITADEL ADVISORS LLC 0.01% of their portfolio | 102.1k $11.3m | — |
| PINNACLE ASSOCIATES LTD 0.26% of their portfolio | 101.6k $11.2m | — |
| SOROS FUND MANAGEMENT LLC 0.21% of their portfolio | 101.5k $11.2m | — |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC 0.19% of their portfolio | 99.5k $11.0m | — |
| Bridgewater Associates, LP 0.06% of their portfolio | 98.4k $10.9m | — |
| Tri Locum Partners LP 3.01% of their portfolio | 95.4k $10.6m | — |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 94.2k $10.4m | — |
| RHUMBLINE ADVISERS 0.02% of their portfolio | 93.9k $10.4m | — |
| NEW YORK STATE COMMON RETIREMENT FUND 0.01% of their portfolio | 90.2k $10.0m | — |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 0.03% of their portfolio | 90.2k $10.0m | — |
| JANE STREET GROUP, LLC 0.02% of their portfolio | 88.8k $9.8m | — |
| SEI INVESTMENTS CO 0.02% of their portfolio | 88.6k $9.8m | — |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND 0.05% of their portfolio | 85.7k $9.5m | — |
| STATE OF WISCONSIN INVESTMENT BOARD 0.03% of their portfolio | 84.5k $9.3m | — |
| Legal & General Group Plc 0.00% of their portfolio | 77.9k $8.6m | — |
| 1832 Asset Management L.P. 0.02% of their portfolio | 75.7k $8.4m | — |
| PEREGRINE CAPITAL MANAGEMENT LLC 0.27% of their portfolio | 74.3k $8.2m | — |
| Man Group plc 0.04% of their portfolio | 71.4k $7.9m | — |
| UBS Group AG 0.00% of their portfolio | 70.7k $7.8m | — |