REZOLUTE INC RZLT
COM NEW · Common Stock · CUSIP 76200L309
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersRedwood City, CA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($725.7k this quarter). Holder counts are more reliable. Shares outstanding: 96.3m as of 2026-05-08, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $5.20. Options: 8 managers hold calls ($16.2m notional), 5 hold puts ($1.2m).
Trends to Q2 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 34 |
| Q4 2022 | 35 |
| Q1 2023 | 33 |
| Q2 2023 | 30 |
| Q3 2023 | 31 |
| Q4 2023 | 33 |
| Q1 2024 | 34 |
| Q2 2024 | 53 |
| Q3 2024 | 60 |
| Q4 2024 | 72 |
| Q1 2025 | 78 |
| Q2 2025 | 93 |
| Q3 2025 | 116 |
| Q4 2025 | 122 |
| Q1 2026 | 126 |
| Q2 2026 | 144 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2024 | 37 | 21 |
| Q4 2024 | 42 | 28 |
| Q1 2025 | 49 | 29 |
| Q2 2025 | 76 | 41 |
| Q3 2025 | 74 | 39 |
| Q4 2025 | 83 | 57 |
| Q1 2026 | 68 | 69 |
| Q2 2026 | 97 | 49 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2025 | $10.4m | $705.8k | 0.07 |
| Q4 2025 | $4.6m | $1.8m | 0.40 |
| Q1 2026 | $4.9m | $832.6k | 0.17 |
| Q2 2026 | $16.2m | $1.2m | 0.07 |
Biggest buyers
| JACOBS LEVY EQUITY MANAGEMENT, INC | Added | +2.3m |
| BlackRock, Inc. | Added | +1.4m |
| Nuveen, LLC | Added | +1.2m |
| Ikarian Capital, LLC | Added | +918.5k |
| GOLDMAN SACHS GROUP INC | Added | +714.5k |
| Squadron Capital Management LLC | New | +403.4k |
| Vestal Point Capital, LP | New | +383.0k |
| DIMENSIONAL FUND ADVISORS LP | Added | +360.5k |
| VANGUARD CAPITAL MANAGEMENT LLC | Added | +313.7k |
| Driehaus Capital Management LLC | New | +289.5k |
Biggest sellers
| BANK OF AMERICA CORP /DE/ | Reduced | -2.2m |
| VANGUARD PORTFOLIO MANAGEMENT LLC | Reduced | -1.6m |
| Integral Health Asset Management, LLC | Reduced | -1.5m |
| UBS Group AG | Reduced | -1.4m |
| MORGAN STANLEY | Reduced | -1.1m |
| MILLENNIUM MANAGEMENT LLC | Reduced | -1.0m |
| JENNISON ASSOCIATES LLC | Reduced | -979.6k |
| Affinity Asset Advisors, LLC | Reduced | -547.6k |
| TWO SIGMA INVESTMENTS, LP | Reduced | -399.5k |
| Balyasny Asset Management L.P. | Reduced | -386.4k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $7.8m1.5m shares |
| Squadron Capital Management LLC | New | $4.7m900.0k shares |
| SIMPLEX TRADING, LLC | Added | $1.2m232.2k shares |
| CITADEL ADVISORS LLC | Added | $957.3k184.1k shares |
| Centiva Capital, LP | Reduced | $822.6k158.2k shares |
| Caption Management, LLC | New | $520.0k100.0k shares |
| HRT FINANCIAL LP | New | $169.0k32.5k shares |
| GROUP ONE TRADING LLC | Reduced | $116.0k22.3k shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $488.3k93.9k shares |
| SIMPLEX TRADING, LLC | Reduced | $358.3k68.9k shares |
| CITADEL ADVISORS LLC | Added | $208.0k40.0k shares |
| HRT FINANCIAL LP | Reduced | $146.0k28.1k shares |
| GROUP ONE TRADING LLC | Reduced | $2.6k500 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| RA CAPITAL MANAGEMENT, L.P. 13G · passive investor new · filed 2025-12-18 | 9.9% |
| Opaleye Management Inc. 13G · passive investor +1.3 pts · filed 2026-05-11 | 6.6% |
| Dellora Investments LP 13G · passive investor new · filed 2026-08-12 | 5.9% |
| JENNISON ASSOCIATES LLC 13G · institution new · filed 2026-10-28 | 5.5% |
| BlackRock, Inc. 13G · institution new · filed 2025-10-17 | 5.4% |
Fell to 5% or below in the last year: BALYASNY ASSET MANAGEMENT L.P. (4.8%, 2026-08-14), BANK OF AMERICA CORP /DE/ (1.2%, 2026-08-12), VANGUARD GROUP INC (0.0%, 2026-03-26), Invus Global Management, LLC (0.0%, 2026-02-13), FMR LLC (2.5%, 2026-01-08)
Insider purchases and sales since 1 Apr 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2024 | 1 | $84.3k | 0 | — | — |
| Q1 2025 | 3 | $159.5k | 0 | — | — |
| Q2 2025 | 4 | $4.0m | 0 | — | — |
| Q3 2025 | 0 | — | 0 | — | — |
| Q4 2025 | 5 | $207.4k | 0 | — | — |
| Q1 2026 | 1 | $28.5k | 0 | — | — |
| Q2 2026 | 0 | — | 0 | — | — |
| Q3 2026 | 0 | — | 0 | — | — |
None reported since 1 Apr 2026.
Holders, Q2 2026
| Manager | Shares | Change |
|---|---|---|
| FEDERATED HERMES, INC. 0.10% of their portfolio | 13.0m $67.6m | Unchanged |
| RA CAPITAL MANAGEMENT, L.P. 0.43% of their portfolio | 9.4m $49.1m | Added +265.0k |
| BlackRock, Inc. 0.00% of their portfolio | 7.7m $40.1m | Added +1.4m |
| Opaleye Management Inc. 2.97% of their portfolio | 6.3m $32.8m | Unchanged |
| Balyasny Asset Management L.P. 0.04% of their portfolio | 4.7m $24.2m | Reduced -386.4k |
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 3.8m $19.9m | Added +313.7k |
| Siren, L.L.C. 0.35% of their portfolio | 3.3m $17.3m | Unchanged |
| JACOBS LEVY EQUITY MANAGEMENT, INC 0.05% of their portfolio | 2.6m $13.3m | Added +2.3m |
| JENNISON ASSOCIATES LLC 0.01% of their portfolio | 2.5m $12.8m | Reduced -979.6k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 2.2m $11.3m | Added +205.8k |
| STATE STREET CORP 0.00% of their portfolio | 1.9m $9.6m | Added +78.3k |
| D. E. Shaw & Co., Inc. 0.01% of their portfolio | 1.8m $9.6m | Added +73.4k |
| MORGAN STANLEY 0.00% of their portfolio | 1.6m $8.4m | Reduced -1.1m |
| VANGUARD PORTFOLIO MANAGEMENT LLC 0.00% of their portfolio | 1.4m $7.2m | Reduced -1.6m |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 1.3m $6.8m | Added +714.5k |
| Nuveen, LLC 0.00% of their portfolio | 1.3m $6.7m | Added +1.2m |
| KENNEDY CAPITAL MANAGEMENT LLC 0.11% of their portfolio | 1.2m $6.4m | Reduced -14.4k |
| Blackstone Inc. 0.02% of their portfolio | 1.1m $5.6m | Not comparable |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 1.0m $5.2m | Added +211.3k |
| Affinity Asset Advisors, LLC 0.25% of their portfolio | 1.0m $5.2m | Reduced -547.6k |
| GREAT POINT PARTNERS LLC 1.17% of their portfolio | 951.8k $4.9m | Unchanged |
| Ikarian Capital, LLC 0.80% of their portfolio | 935.0k $4.9m | Added +918.5k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 890.7k $4.6m | Added +360.5k |
| 22NW, LP 4.08% of their portfolio | 820.7k $4.3m | Unchanged |
| Velan Capital Investment Management LP 2.39% of their portfolio | 750.0k $3.9m | Unchanged |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 730.3k $3.8m | Reduced -2.2m |
| NORTHERN TRUST CORP 0.00% of their portfolio | 725.3k $3.8m | Added +92.5k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 723.6k $3.8m | Added +85.2k |
| Woodline Partners LP 0.01% of their portfolio | 611.8k $3.2m | Unchanged |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 571.0k $3.0m | Reduced -28.8k |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 517.2k $2.7m | Reduced -1.0m |
| J. Goldman & Co LP 0.09% of their portfolio | 500.4k $2.6m | Reduced -85.5k |
| Integral Health Asset Management, LLC 0.11% of their portfolio | 500.0k $2.6m | Reduced -1.5m |
| UBS Group AG 0.00% of their portfolio | 496.0k $2.6m | Reduced -1.4m |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 431.1k $2.2m | Reduced -399.5k |
| Squadron Capital Management LLC 0.72% of their portfolio | 403.4k $2.1m | New |
| Vestal Point Capital, LP 0.05% of their portfolio | 383.0k $2.0m | New |
| Knott David M Jr 1.02% of their portfolio | 370.0k $1.9m | Unchanged |
| XTX Topco Ltd 0.02% of their portfolio | 353.7k $1.8m | Added +60.8k |
| Jupiter Topco LLC 0.00% of their portfolio | 332.3k $1.7m | First filing |
| Driehaus Capital Management LLC 0.01% of their portfolio | 289.5k $1.5m | New |
| BOOTHBAY FUND MANAGEMENT, LLC 0.03% of their portfolio | 287.0k $1.5m | New |
| Susquehanna Portfolio Strategies, LLC 0.02% of their portfolio | 279.6k $1.5m | Added +165.3k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 263.9k $1.4m | Reduced -279.5k |
| Schonfeld Strategic Advisors LLC 0.01% of their portfolio | 263.7k $1.4m | New |
| FMR LLC 0.00% of their portfolio | 216.1k $1.1m | Added +158.8k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 212.3k $1.1m | Added +22.5k |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 210.0k $1.1m | Added +163.9k |
| BARCLAYS PLC 0.00% of their portfolio | 156.4k $813.2k | Reduced -339.1k |
| GROUP ONE TRADING LLC 0.02% of their portfolio | 152.0k $790.3k | Added +85.8k |
| PFM Health Sciences, LP 0.06% of their portfolio | 127.3k $661.9k | Reduced -1.4k |
| Pavaki Capital Management LLC 0.36% of their portfolio | 120.0k $624.0k | Unchanged |
| Creative Planning 0.00% of their portfolio | 117.4k $610.3k | Added +77.9k |
| Walleye Capital LLC 0.00% of their portfolio | 108.6k $564.5k | New |
| FRANKLIN RESOURCES INC 0.00% of their portfolio | 104.7k $544.5k | New |
| SIMPLEX TRADING, LLC 0.01% of their portfolio | 101.2k $526.5k | Added +66.1k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 98.5k $512.1k | Reduced -16.9k |
| ALPS ADVISORS INC 0.00% of their portfolio | 97.7k $508.2k | Added +19.7k |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 97.7k $507.8k | New |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 94.3k $490.3k | Added +5.9k |
| SEI INVESTMENTS CO 0.00% of their portfolio | 93.5k $486.1k | Reduced -53.1k |
| State of Alaska, Department of Revenue 0.00% of their portfolio | 87.0k $452.0k | Unchanged |
| Virtus Investment Advisers, LLC 0.10% of their portfolio | 81.8k $425.4k | Reduced -69.7k |
| Jain Global LLC 0.00% of their portfolio | 80.9k $420.9k | New |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 80.8k $420.1k | Added +16.6k |
| NATIXIS 0.00% of their portfolio | 78.0k $405.6k | New |
| LOS ANGELES CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 77.8k $404.7k | New |
| MARSHALL WACE, LLP 0.00% of their portfolio | 75.8k $394.4k | Added +23.3k |
| AlphaCentric Advisors LLC 0.32% of their portfolio | 72.3k $375.7k | Added +1.0k |
| ACADIAN ASSET MANAGEMENT LLC 0.00% of their portfolio | 70.1k $362.0k | Added +36.4k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 68.3k $208.3k | Added +24.4k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 67.9k $353.2k | Added +40.5k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 63.6k $331.0k | Added +6.0k |
| Mariner, LLC 0.00% of their portfolio | 61.8k $321.2k | Added +14.0k |
| HSBC HOLDINGS PLC 0.00% of their portfolio | 53.6k $277.6k | Added +16.7k |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 53.0k $275.7k | New |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO 0.00% of their portfolio | 51.3k $266.8k | New |
| Integrated Wealth Concepts LLC 0.00% of their portfolio | 50.1k $260.8k | New |
| ADAR1 Capital Management, LLC 0.01% of their portfolio | 48.7k $253.1k | Reduced -10.0k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 47.2k $245.5k | Added +5.1k |
| Invesco Ltd. 0.00% of their portfolio | 40.7k $211.5k | Added +351 |
| CANADA PENSION PLAN INVESTMENT BOARD 0.00% of their portfolio | 39.5k $205.4k | New |
| CITIGROUP INC 0.00% of their portfolio | 36.2k $188.1k | Added +32.4k |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 36.0k $187.4k | Added +2.1k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 35.8k $182.3k | Added +4.3k |
| MERCER GLOBAL ADVISORS INC /ADV 0.00% of their portfolio | 35.6k $185.1k | Added +11.4k |
| Vanguard Global Advisers, LLC 0.00% of their portfolio | 35.2k $183.0k | Reduced -38.9k |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC 0.00% of their portfolio | 34.7k $164.9k | Added +8.9k |
| IEQ CAPITAL, LLC 0.00% of their portfolio | 30.8k $160.1k | New |
| Cerity Partners LLC 0.00% of their portfolio | 28.8k $150.0k | Added +8.9k |
| Quadrature Capital Ltd 0.00% of their portfolio | 25.4k $131.9k | New |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 25.0k $130.0k | New |
| SG Americas Securities, LLC 0.00% of their portfolio | 23.5k $122.0k | New |
| CAPTRUST FINANCIAL ADVISORS 0.00% of their portfolio | 23.2k $120.7k | Added +9.0k |
| Virtu Financial LLC 0.00% of their portfolio | 22.8k $119.0k | New |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 21.9k $114.0k | Added +1.4k |
| Police & Firemen's Retirement System of New Jersey 0.00% of their portfolio | 21.8k $113.4k | Unchanged |
| Rangeley Capital, LLC 0.10% of their portfolio | 19.6k $102.2k | Reduced -20.4k |
| EntryPoint Capital, LLC 0.02% of their portfolio | 19.5k $101.2k | New |
| INTECH INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 18.8k $97.6k | Reduced -1.3k |