REVOLUTION MEDICINES INC RVMD
COM · Common Stock · CUSIP 76155X100 · ISIN US76155X1000
Company in Redwood City, United States
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersRedwood City, CA
- Founded2014
- Websiterevmed.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Shares outstanding: 165.0m as of 2024-05-02, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $32.23. Options: 11 managers hold calls ($12.2m notional), 8 hold puts ($4.6m).
Trends to Q1 2024
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 142 |
| Q4 2022 | 136 |
| Q1 2023 | 153 |
| Q2 2023 | 140 |
| Q3 2023 | 169 |
| Q4 2023 | 185 |
| Q1 2024 | 211 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 70 | 63 |
| Q1 2023 | 109 | 46 |
| Q2 2023 | 69 | 66 |
| Q3 2023 | 102 | 52 |
| Q4 2023 | 126 | 70 |
| Q1 2024 | 105 | 89 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q2 2023 | $5.1m | $2.7m | 0.53 |
| Q3 2023 | $22.9m | $19.7m | 0.86 |
| Q4 2023 | $19.1m | $10.2m | 0.53 |
| Q1 2024 | $12.2m | $4.6m | 0.38 |
Biggest buyers
| Paradigm Biocapital Advisors LP | New | +2.9m |
| BAKER BROS. ADVISORS LP | Added | +2.4m |
| JANUS HENDERSON GROUP PLC | Added | +1.7m |
| NORGES BANK | Added | +1.4m |
| Balyasny Asset Management L.P. | Added | +1.1m |
| Woodline Partners LP | Added | +837.1k |
| FARALLON CAPITAL MANAGEMENT, L.L.C. | Added | +771.0k |
| Avidity Partners Management LP | Added | +575.0k |
| Soleus Capital Management, L.P. | Added | +476.7k |
| Mass General Brigham, Inc | New | +338.2k |
Biggest sellers
| ARCH Venture Management, LLC | Sold out | -3.2m |
| a16z Capital Management, L.L.C. | Reduced | -2.9m |
| JPMORGAN CHASE & CO | Reduced | -1.8m |
| Bain Capital Life Sciences Investors, LLC | Sold out | -1.1m |
| STATE STREET CORP | Reduced | -867.3k |
| Vestal Point Capital, LP | Sold out | -725.0k |
| TANG CAPITAL MANAGEMENT LLC | Sold out | -679.6k |
| BlackRock Inc. | Reduced | -646.3k |
| MORGAN STANLEY | Reduced | -525.1k |
| DIMENSIONAL FUND ADVISORS LP | Reduced | -464.2k |
Biggest calls
| MILLENNIUM MANAGEMENT LLC | Added | $4.2m130.0k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $3.0m94.0k shares |
| GROUP ONE TRADING LLC | Reduced | $1.3m41.8k shares |
| BARCLAYS PLC | New | $805.8k25.0k shares |
| CITADEL ADVISORS LLC | Reduced | $683.6k21.2k shares |
| CITIGROUP INC | Reduced | $676.8k21.0k shares |
| Squarepoint Ops LLC | New | $483.4k15.0k shares |
| Caption Management, LLC | Reduced | $483.4k15.0k shares |
| JANE STREET GROUP, LLC | Reduced | $383.5k11.9k shares |
| SIMPLEX TRADING, LLC | Reduced | $122.0k3.8k shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $1.5m45.4k shares |
| GROUP ONE TRADING LLC | Reduced | $854.1k26.5k shares |
| BARCLAYS PLC | New | $805.8k25.0k shares |
| Squarepoint Ops LLC | New | $483.4k15.0k shares |
| Caption Management, LLC | Reduced | $483.4k15.0k shares |
| CITADEL ADVISORS LLC | Reduced | $354.5k11.0k shares |
| SIMPLEX TRADING, LLC | Reduced | $203.0k6.3k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| Farallon Capital Partners, L.P. 13G · passive investor -0.4 pts · filed 2026-02-09 | 7.5% |
| FARALLON CAPITAL MANAGEMENT, L.L.C. 13G · institution filed 2026-08-13 | 6.4% |
| BlackRock, Inc. 13G · institution +1.2 pts · filed 2026-07-29 | 5.7% |
| BAKER BROS. ADVISORS LP 13G · institution +0.4 pts · filed 2026-08-14 | 5.3% |
| Janus Henderson Group Ltd. 13G · institution +0.2 pts · filed 2026-08-13 | 5.1% |
Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-27), WELLINGTON MANAGEMENT GROUP LLP (3.6%, 2026-02-10)
Insider purchases and sales in Q1 2024
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q2 2022 | 0 | — | 4 | $39.3k | — |
| Q3 2022 | 2 | $6.0m | 4 | $46.7k | — |
| Q4 2022 | 0 | — | 4 | $1.1m | — |
| Q1 2023 | 1 | $14.1m | 4 | $56.8k | — |
| Q2 2023 | 0 | — | 4 | $114.6k | — |
| Q3 2023 | 0 | — | 6 | $4.9m | $2.6m |
| Q4 2023 | 0 | — | 5 | $3.0m | $3.0m |
| Q1 2024 | 0 | — | 5 | $1.8m | $1.8m |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2024-03-27 | Cislini Jeff General Counsel | Sold plan | $46.5k1.5k shares |
| 2024-03-18 | GOLDSMITH MARK A Officer, director | Sold plan | $182.8k5.8k shares |
| 2024-03-18 | Horn Margaret A Chief Operating Officer | Sold plan | $92.0k2.9k shares |
| 2024-03-18 | Kelsey Stephen Michael Officer | Sold plan | $67.0k2.1k shares |
| 2024-03-18 | Anders Jack Chief Financial Officer | Sold plan | $39.8k1.3k shares |
| 2024-03-18 | Cislini Jeff General Counsel | Sold plan | $39.5k1.3k shares |
| 2024-03-12 | Horn Margaret A Chief Operating Officer | Sold plan | $270.4k7.9k shares |
| 2024-03-11 | Horn Margaret A Chief Operating Officer | Sold plan | $535.3k15.7k shares |
| 2024-01-22 | Cislini Jeff General Counsel | Sold plan | $40.5k1.5k shares |
| 2024-01-08 | Kelsey Stephen Michael Officer | Sold plan | $96.8k3.3k shares |
| 2024-01-02 | Kelsey Stephen Michael Officer | Sold plan | $387.9k13.3k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q1 2024
| Manager | Shares | Change |
|---|---|---|
| VANGUARD GROUP INC 0.01% of their portfolio | 14.8m $475.6m | Added +122.7k |
| WELLINGTON MANAGEMENT GROUP LLP 0.08% of their portfolio | 14.7m $474.3m | Reduced -167.4k |
| BlackRock Inc. 0.01% of their portfolio | 12.3m $396.7m | Reduced -646.3k |
| BAKER BROS. ADVISORS LP 3.05% of their portfolio | 7.5m $243.3m | Added +2.4m |
| FARALLON CAPITAL MANAGEMENT, L.L.C. 1.42% of their portfolio | 7.5m $242.0m | Added +771.0k |
| JPMORGAN CHASE & CO 0.01% of their portfolio | 7.0m $226.2m | Reduced -1.8m |
| Nextech Invest Ltd. 32.17% of their portfolio | 6.3m $202.9m | Unchanged |
| BVF INC/IL 5.30% of their portfolio | 6.0m $192.8m | Unchanged |
| Casdin Capital, LLC 13.47% of their portfolio | 5.6m $181.1m | Reduced -97.2k |
| STATE STREET CORP 0.01% of their portfolio | 5.4m $173.6m | Reduced -867.3k |
| Alphabet Inc. 6.80% of their portfolio | 5.3m $170.9m | Unchanged |
| Bellevue Group AG 2.49% of their portfolio | 5.1m $163.5m | Reduced -17.4k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.02% of their portfolio | 4.8m $155.2m | Added +178.0k |
| Boxer Capital, LLC 6.81% of their portfolio | 4.3m $137.9m | Unchanged |
| FMR LLC 0.01% of their portfolio | 4.2m $134.3m | Added +2.6k |
| JANUS HENDERSON GROUP PLC 0.07% of their portfolio | 3.9m $126.1m | Added +1.7m |
| Woodline Partners LP 1.13% of their portfolio | 3.8m $122.4m | Added +837.1k |
| DEERFIELD MANAGEMENT COMPANY, L.P. 1.73% of their portfolio | 3.1m $99.6m | Unchanged |
| GEODE CAPITAL MANAGEMENT, LLC 0.01% of their portfolio | 3.1m $98.4m | Added +73.9k |
| Paradigm Biocapital Advisors LP 3.31% of their portfolio | 2.9m $93.9m | New |
| MORGAN STANLEY 0.00% of their portfolio | 2.8m $89.6m | Reduced -525.1k |
| a16z Capital Management, L.L.C. 6.41% of their portfolio | 2.7m $88.6m | Reduced -2.9m |
| Holocene Advisors, LP 0.29% of their portfolio | 2.4m $78.1m | Reduced -459.7k |
| NORGES BANK 0.01% of their portfolio | 1.7m $55.1m | Added +1.4m |
| AMERIPRISE FINANCIAL INC 0.02% of their portfolio | 1.7m $54.6m | Added +71.5k |
| Balyasny Asset Management L.P. 0.14% of their portfolio | 1.7m $53.3m | Added +1.1m |
| MARSHALL WACE, LLP 0.08% of their portfolio | 1.5m $49.5m | Added +327.0k |
| DIMENSIONAL FUND ADVISORS LP 0.01% of their portfolio | 1.3m $42.9m | Reduced -464.2k |
| Artal Group S.A. 1.10% of their portfolio | 1.3m $42.5m | Reduced -377.3k |
| NORTHERN TRUST CORP 0.01% of their portfolio | 1.2m $39.1m | Reduced -56.5k |
| GOLDMAN SACHS GROUP INC 0.01% of their portfolio | 1.1m $36.2m | Added +70.2k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.01% of their portfolio | 1.1m $33.9m | Added +9.3k |
| Frazier Life Sciences Management, L.P. 1.36% of their portfolio | 997.5k $32.1m | Unchanged |
| Rock Springs Capital Management LP 0.76% of their portfolio | 923.7k $29.8m | Added +198.5k |
| Soleus Capital Management, L.P. 2.06% of their portfolio | 728.7k $23.5m | Added +476.7k |
| Finepoint Capital LP 5.60% of their portfolio | 677.1k $21.8m | Added +60.0k |
| Avidity Partners Management LP 0.73% of their portfolio | 635.0k $20.5m | Added +575.0k |
| PERCEPTIVE ADVISORS LLC 0.35% of their portfolio | 618.9k $19.9m | Reduced -200.0k |
| VICTORY CAPITAL MANAGEMENT INC 0.02% of their portfolio | 600.6k $19.4m | Added +42.2k |
| CITADEL ADVISORS LLC 0.02% of their portfolio | 588.1k $19.0m | Reduced -315.9k |
| Candriam S.C.A. 0.12% of their portfolio | 584.0k $18.8m | Reduced -23.0k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 544.1k $17.5m | Added +298.1k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 529.4k $17.1m | Reduced -51.8k |
| DAFNA Capital Management LLC 3.76% of their portfolio | 511.9k $16.5m | Unchanged |
| MIC Capital Management UK LLP 3.11% of their portfolio | 508.6k $16.4m | Unchanged |
| Integral Health Asset Management, LLC 1.33% of their portfolio | 420.0k $13.5m | Added +220.0k |
| Nuveen Asset Management, LLC 0.00% of their portfolio | 373.8k $12.0m | Reduced -10.9k |
| EVENTIDE ASSET MANAGEMENT, LLC 0.18% of their portfolio | 361.0k $11.6m | Unchanged |
| Mass General Brigham, Inc 19.08% of their portfolio | 338.2k $10.9m | New |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 323.4k $10.4m | Added +3.1k |
| UBS Group AG 0.00% of their portfolio | 305.0k $9.8m | Reduced -1.6k |
| VOYA INVESTMENT MANAGEMENT LLC 0.01% of their portfolio | 291.5k $9.4m | Added +108.3k |
| GREAT LAKES ADVISORS, LLC 0.08% of their portfolio | 288.8k $9.3m | New |
| Rafferty Asset Management, LLC 0.03% of their portfolio | 284.4k $9.2m | Reduced -80.7k |
| Mubadala Investment Co PJSC 0.04% of their portfolio | 278.0k $9.0m | Unchanged |
| CITIGROUP INC 0.01% of their portfolio | 277.7k $8.9m | Added +116.6k |
| MPM BIOIMPACT LLC 1.43% of their portfolio | 273.2k $8.8m | Reduced -191 |
| TD Asset Management Inc 0.01% of their portfolio | 254.6k $8.2m | Reduced -17.2k |
| BESSEMER GROUP INC 0.01% of their portfolio | 243.4k $7.8m | Unchanged |
| RHUMBLINE ADVISERS 0.01% of their portfolio | 209.3k $6.7m | Added +4.0k |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC 0.31% of their portfolio | 206.5k $6.7m | New |
| Swiss National Bank 0.00% of their portfolio | 200.1k $6.5m | Unchanged |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.01% of their portfolio | 200.0k $6.4m | New |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.01% of their portfolio | 199.1k $6.4m | Added +20.1k |
| Qube Research & Technologies Ltd 0.01% of their portfolio | 167.5k $5.4m | Added +142.0k |
| HSBC HOLDINGS PLC 0.00% of their portfolio | 167.1k $5.4m | New |
| ACUTA CAPITAL PARTNERS, LLC 3.01% of their portfolio | 143.8k $4.6m | Reduced -16.2k |
| NEUBERGER BERMAN GROUP LLC 0.00% of their portfolio | 143.4k $4.6m | Added +57.6k |
| BARCLAYS PLC 0.00% of their portfolio | 135.4k $4.4m | Reduced -218.4k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 133.2k $4.3m | Unchanged |
| JANE STREET GROUP, LLC 0.01% of their portfolio | 129.5k $4.2m | Reduced -66.8k |
| ALPS ADVISORS INC 0.03% of their portfolio | 116.2k $3.7m | Added +5.0k |
| CREDIT SUISSE AG/ 0.00% of their portfolio | 112.3k $3.6m | Added +16.5k |
| Legal & General Group Plc 0.00% of their portfolio | 106.1k $3.4m | Reduced -2.6k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 105.4k $3.4m | Reduced -8.7k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 96.9k $3.1m | Reduced -21.0k |
| Invesco Ltd. 0.00% of their portfolio | 94.4k $3.0m | Reduced -34.4k |
| State of New Jersey Common Pension Fund D 0.01% of their portfolio | 91.8k $3.0m | Reduced -21.6k |
| STATE OF WISCONSIN INVESTMENT BOARD 0.01% of their portfolio | 74.1k $2.4m | Reduced -9.5k |
| D. E. Shaw & Co., Inc. 0.00% of their portfolio | 73.7k $2.4m | Added +22.6k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 72.6k $2.3m | Reduced -76.0k |
| MetLife Investment Management, LLC 0.02% of their portfolio | 71.2k $2.3m | Reduced -4.2k |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC 0.01% of their portfolio | 70.8k $2.3m | New |
| AMERICAN INTERNATIONAL GROUP, INC. 0.01% of their portfolio | 68.7k $2.2m | Reduced -2.8k |
| SEVEN EIGHT CAPITAL, LP 0.23% of their portfolio | 68.5k $2.2m | New |
| READYSTATE ASSET MANAGEMENT LP 0.08% of their portfolio | 67.3k $2.2m | New |
| HRT FINANCIAL LP 0.01% of their portfolio | 64.1k $2.1m | New |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 60.4k $1.9m | Reduced -455 |
| MOORE CAPITAL MANAGEMENT, LP 0.04% of their portfolio | 55.6k $1.8m | Unchanged |
| TWO SIGMA ADVISERS, LP 0.00% of their portfolio | 52.0k $1.7m | Reduced -13.8k |
| Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio | 51.1k $1.2m | Reduced -29.3k |
| DekaBank Deutsche Girozentrale 0.00% of their portfolio | 50.0k $1.6m | Unchanged |
| Wedmont Private Capital 0.12% of their portfolio | 49.6k $1.6m | Unchanged |
| GUGGENHEIM CAPITAL LLC 0.01% of their portfolio | 48.6k $1.6m | Reduced -3.1k |
| PROFUND ADVISORS LLC 0.06% of their portfolio | 46.1k $1.5m | Reduced -15.0k |
| Connor, Clark & Lunn Investment Management Ltd. 0.01% of their portfolio | 44.9k $1.4m | New |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 43.8k $1.4m | Added +3.8k |
| Handelsbanken Fonder AB 0.01% of their portfolio | 40.2k $1.3m | Unchanged |
| Ensign Peak Advisors, Inc 0.00% of their portfolio | 39.8k $1.3m | Reduced -2.0k |
| Cinctive Capital Management LP 0.06% of their portfolio | 38.2k $1.2m | Reduced -26.9k |