REPLIGEN CORP RGEN
COM · Common Stock · CUSIP 759916109 · ISIN US7599161095
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersWaltham, MA
- Founded1981
- Websiterepligen.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($19.3m this quarter). Holder counts are more reliable. Shares outstanding: 56.0m as of 2024-07-26, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $126.01. Options: 14 managers hold calls ($66.9m notional), 10 hold puts ($18.1m).
Trends to Q2 2024
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 434 |
| Q4 2022 | 443 |
| Q1 2023 | 448 |
| Q2 2023 | 448 |
| Q3 2023 | 440 |
| Q4 2023 | 467 |
| Q1 2024 | 487 |
| Q2 2024 | 455 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 222 | 201 |
| Q1 2023 | 207 | 201 |
| Q2 2023 | 218 | 219 |
| Q3 2023 | 213 | 217 |
| Q4 2023 | 209 | 203 |
| Q1 2024 | 230 | 204 |
| Q2 2024 | 220 | 257 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2023 | $36.9m | $34.0m | 0.92 |
| Q4 2023 | $143.2m | $83.2m | 0.58 |
| Q1 2024 | $212.4m | $46.9m | 0.22 |
| Q2 2024 | $66.9m | $18.1m | 0.27 |
Biggest buyers
| PRICE T ROWE ASSOCIATES INC /MD/ | Added | +1.0m |
| MILLENNIUM MANAGEMENT LLC | New | +756.1k |
| Impax Asset Management Group plc | Added | +445.9k |
| Thrivent Financial for Lutherans | Added | +425.1k |
| Bank of New York Mellon Corp | Added | +237.9k |
| TWO SIGMA INVESTMENTS, LP | Added | +210.8k |
| Conestoga Capital Advisors, LLC | Added | +199.3k |
| Eversept Partners, LP | Added | +186.1k |
| BRAIDWELL LP | Added | +180.7k |
| AMERIPRISE FINANCIAL INC | Added | +160.7k |
Biggest sellers
| MORGAN STANLEY | Reduced | -1.1m |
| FMR LLC | Reduced | -813.0k |
| Artisan Partners Limited Partnership | Reduced | -716.8k |
| WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC | Sold out | -635.0k |
| Holocene Advisors, LP | Sold out | -342.4k |
| WELLINGTON MANAGEMENT GROUP LLP | Reduced | -324.6k |
| MACQUARIE GROUP LTD | Reduced | -242.7k |
| Point72 Asset Management, L.P. | Reduced | -226.4k |
| BAMCO INC /NY/ | Reduced | -208.8k |
| BlackRock Inc. | Reduced | -204.7k |
Biggest calls
| BARCLAYS PLC | Reduced | $15.3m121.0k shares |
| CITADEL ADVISORS LLC | Reduced | $13.1m103.8k shares |
| JANE STREET GROUP, LLC | Added | $7.7m60.9k shares |
| MILLENNIUM MANAGEMENT LLC | New | $6.4m50.5k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $5.0m40.0k shares |
| Walleye Capital LLC | Reduced | $4.5m35.6k shares |
| IMC-Chicago, LLC | Added | $3.7m29.3k shares |
| Twin Tree Management, LP | Reduced | $3.4m27.2k shares |
| Walleye Trading LLC | Reduced | $3.2m25.6k shares |
| SIMPLEX TRADING, LLC | Reduced | $2.1m16.9k shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $3.4m27.3k shares |
| JANE STREET GROUP, LLC | Added | $3.4m27.3k shares |
| D. E. Shaw & Co., Inc. | New | $2.5m20.0k shares |
| IMC-Chicago, LLC | New | $2.4m19.4k shares |
| CITADEL ADVISORS LLC | Reduced | $1.6m12.5k shares |
| Walleye Trading LLC | Reduced | $1.5m12.0k shares |
| SIMPLEX TRADING, LLC | Added | $1.4m11.4k shares |
| MILLENNIUM MANAGEMENT LLC | Added | $1.4m11.3k shares |
| Walleye Capital LLC | Added | $277.3k2.2k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| FMR LLC 13G · institution +7.9 pts · filed 2026-10-07 | 13.0% |
| BlackRock, Inc. 13G · institution filed 2025-04-24 | 9.3% |
| VANGUARD CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-07-31 | 5.0% |
Fell to 5% or below in the last year: PRICE T ROWE ASSOCIATES INC /MD/ (3.1%, 2026-08-14), VANGUARD GROUP INC (0.0%, 2026-03-27; now reported by VANGUARD CAPITAL MANAGEMENT LLC), Roy T. Eddleman Living Trust (4.8%, 2026-02-13)
Insider purchases and sales in Q2 2024
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q3 2022 | 0 | — | 6 | $15.7m | — |
| Q4 2022 | 0 | — | 1 | $5.0m | — |
| Q1 2023 | 0 | — | 1 | $1.1m | — |
| Q2 2023 | 1 | $238.3k | 0 | — | — |
| Q3 2023 | 0 | — | 1 | $145.7k | — |
| Q4 2023 | 0 | — | 1 | $557.3k | — |
| Q1 2024 | 0 | — | 4 | $5.0m | $3.3m |
| Q2 2024 | 3 | $600.5k | 1 | $3.4m | $3.4m |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2024-06-14 | Hunt Anthony Chief Executive Officer | Bought | $248.2k2.0k shares |
| 2024-06-14 | Madaus Martin D Director | Bought | $201.8k1.6k shares |
| 2024-06-14 | BARTHELEMY NICOLAS Director | Bought | $150.5k1.2k shares |
| 2024-05-21 | Hunt Anthony Chief Executive Officer | Sold plan | $3.4m20.1k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2024
| Manager | Shares | Change |
|---|---|---|
| BlackRock Inc. 0.02% of their portfolio | 7.6m $954.1m | Reduced -204.7k |
| VANGUARD GROUP INC 0.01% of their portfolio | 5.1m $638.7m | Reduced -33.6k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.07% of their portfolio | 4.6m $580.9m | Added +1.0m |
| STATE STREET CORP 0.01% of their portfolio | 1.7m $219.0m | Reduced -20.8k |
| FMR LLC 0.01% of their portfolio | 1.4m $182.1m | Reduced -813.0k |
| SANDS CAPITAL MANAGEMENT, LLC 0.53% of their portfolio | 1.4m $179.2m | Reduced -11.2k |
| Bank of New York Mellon Corp 0.03% of their portfolio | 1.4m $172.7m | Added +237.9k |
| Invesco Ltd. 0.03% of their portfolio | 1.3m $164.8m | Added +64.3k |
| BROWN CAPITAL MANAGEMENT LLC 3.30% of their portfolio | 1.3m $163.1m | Added +139.0k |
| MACQUARIE GROUP LTD 0.18% of their portfolio | 1.2m $154.0m | Reduced -242.7k |
| Impax Asset Management Group plc 0.57% of their portfolio | 1.1m $141.1m | Added +445.9k |
| AMERIPRISE FINANCIAL INC 0.04% of their portfolio | 1.1m $133.0m | Added +160.7k |
| Conestoga Capital Advisors, LLC 1.79% of their portfolio | 946.9k $119.4m | Added +199.3k |
| GEODE CAPITAL MANAGEMENT, LLC 0.01% of their portfolio | 945.2k $119.0m | Added +23.7k |
| ALLIANCEBERNSTEIN L.P. 0.04% of their portfolio | 823.7k $103.8m | Reduced -20.0k |
| WELLINGTON MANAGEMENT GROUP LLP 0.02% of their portfolio | 784.1k $98.8m | Reduced -324.6k |
| MILLENNIUM MANAGEMENT LLC 0.08% of their portfolio | 756.1k $95.3m | New |
| VOYA INVESTMENT MANAGEMENT LLC 0.08% of their portfolio | 658.1k $83.0m | Added +92.4k |
| Harding Loevner LP 0.44% of their portfolio | 633.0k $79.8m | Reduced -26.4k |
| Thrivent Financial for Lutherans 0.15% of their portfolio | 601.8k $75.9m | Added +425.1k |
| MORGAN STANLEY 0.01% of their portfolio | 575.6k $72.6m | Reduced -1.1m |
| Champlain Investment Partners, LLC 0.44% of their portfolio | 570.6k $71.9m | Reduced -4.4k |
| RIVERBRIDGE PARTNERS LLC 0.90% of their portfolio | 527.9k $66.5m | Added +82.7k |
| Stephens Investment Management Group LLC 0.90% of their portfolio | 512.1k $64.6m | Added +40.4k |
| T. Rowe Price Investment Management, Inc. 0.04% of their portfolio | 510.6k $64.4m | Added +84.1k |
| NEW YORK STATE COMMON RETIREMENT FUND 0.08% of their portfolio | 495.8k $62.5m | Added +83.7k |
| DF DENT & CO INC 0.73% of their portfolio | 450.7k $56.8m | Added +10.8k |
| NORTHERN TRUST CORP 0.01% of their portfolio | 449.3k $56.6m | Added +55.7k |
| Baird Financial Group, Inc. 0.11% of their portfolio | 435.8k $54.9m | Reduced -29.7k |
| DIMENSIONAL FUND ADVISORS LP 0.01% of their portfolio | 429.5k $54.1m | Added +121.3k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 404.9k $51.0m | Reduced -17.9k |
| Artisan Partners Limited Partnership 0.08% of their portfolio | 403.9k $50.9m | Reduced -716.8k |
| PARNASSUS INVESTMENTS, LLC 0.11% of their portfolio | 388.5k $49.0m | Added +108 |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 387.0k $48.8m | Added +48.6k |
| MARSHALL WACE, LLP 0.06% of their portfolio | 364.6k $46.0m | Added +3.9k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.01% of their portfolio | 357.9k $45.1m | Added +5.7k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.01% of their portfolio | 353.9k $44.6m | Added +89.8k |
| BESSEMER GROUP INC 0.08% of their portfolio | 340.2k $42.9m | Added +35.0k |
| Nuveen Asset Management, LLC 0.01% of their portfolio | 338.4k $42.7m | Reduced -200.1k |
| AMERICAN CAPITAL MANAGEMENT INC 1.42% of their portfolio | 336.7k $42.4m | Added +109.4k |
| BRAIDWELL LP 1.28% of their portfolio | 323.5k $40.8m | Added +180.7k |
| FEDERATED HERMES, INC. 0.10% of their portfolio | 321.4k $40.5m | Reduced -183 |
| Point72 Asset Management, L.P. 0.13% of their portfolio | 315.0k $39.7m | Reduced -226.4k |
| FRED ALGER MANAGEMENT, LLC 0.19% of their portfolio | 307.7k $38.8m | Reduced -118.6k |
| FRANKLIN RESOURCES INC 0.01% of their portfolio | 305.7k $38.5m | Added +21.8k |
| GOLDMAN SACHS GROUP INC 0.01% of their portfolio | 301.4k $38.0m | Added +63.1k |
| AMERICAN CENTURY COMPANIES INC 0.02% of their portfolio | 296.2k $37.3m | Reduced -203.3k |
| Allspring Global Investments Holdings, LLC 0.06% of their portfolio | 278.2k $35.1m | Reduced -57.6k |
| EAGLE ASSET MANAGEMENT INC 0.17% of their portfolio | 261.3k $32.2m | Reduced -14.1k |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.08% of their portfolio | 257.5k $32.5m | Reduced -35.2k |
| WESTFIELD CAPITAL MANAGEMENT CO LP 0.16% of their portfolio | 255.8k $32.2m | Added +20.5k |
| 12 West Capital Management LP 3.28% of their portfolio | 252.8k $31.9m | Unchanged |
| PALISADE CAPITAL MANAGEMENT, LP 0.84% of their portfolio | 243.9k $30.7m | Added +59.1k |
| TimesSquare Capital Management, LLC 0.48% of their portfolio | 240.5k $30.3m | Added +46.4k |
| Ranger Investment Management, L.P. 1.90% of their portfolio | 221.4k $27.9m | Added +51.8k |
| TWO SIGMA INVESTMENTS, LP 0.06% of their portfolio | 213.1k $26.9m | Added +210.8k |
| FIRST TRUST ADVISORS LP 0.03% of their portfolio | 208.9k $26.3m | Reduced -45.5k |
| NORGES BANK 0.00% of their portfolio | 204.7k $25.8m | Reduced -54.4k |
| Amundi 0.01% of their portfolio | 202.1k $24.4m | Reduced -33.1k |
| Eversept Partners, LP 1.87% of their portfolio | 194.3k $24.5m | Added +186.1k |
| SEI INVESTMENTS CO 0.03% of their portfolio | 187.5k $23.6m | Reduced -31.2k |
| LORD, ABBETT & CO. LLC 0.04% of their portfolio | 185.3k $23.4m | Reduced -119.5k |
| PRINCIPAL FINANCIAL GROUP INC 0.01% of their portfolio | 173.4k $21.9m | Reduced -172.0k |
| BAMCO INC /NY/ 0.06% of their portfolio | 172.5k $21.7m | Reduced -208.8k |
| Swiss National Bank 0.01% of their portfolio | 156.9k $19.8m | Reduced -1.9k |
| Legal & General Group Plc 0.01% of their portfolio | 153.1k $19.3m | Reduced -7.1k |
| RHUMBLINE ADVISERS 0.02% of their portfolio | 151.7k $19.1m | Reduced -6.2k |
| COMERICA BANK 0.08% of their portfolio | 147.9k $18.6m | Added +24.9k |
| ZEVENBERGEN CAPITAL INVESTMENTS LLC 0.35% of their portfolio | 128.6k $16.2m | Reduced -2.0k |
| GENEVA CAPITAL MANAGEMENT LLC 0.29% of their portfolio | 127.8k $16.1m | Added +9.1k |
| JANE STREET GROUP, LLC 0.02% of their portfolio | 127.2k $16.0m | Added +90.5k |
| NZS Capital, LLC 0.64% of their portfolio | 124.2k $15.7m | Added +42.7k |
| DEUTSCHE BANK AG\ 0.01% of their portfolio | 120.7k $15.2m | Reduced -5.1k |
| EVENTIDE ASSET MANAGEMENT, LLC 0.26% of their portfolio | 119.0k $15.0m | Unchanged |
| PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO 0.06% of their portfolio | 116.5k $14.7m | Added +4.6k |
| Curi Capital, LLC 0.34% of their portfolio | 112.5k $14.2m | Added +967 |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 111.2k $14.0m | Reduced -23.0k |
| ENVESTNET ASSET MANAGEMENT INC 0.00% of their portfolio | 108.7k $13.7m | Added +741 |
| Sumitomo Mitsui Trust Group, Inc. 0.01% of their portfolio | 97.5k $12.3m | Reduced -9.6k |
| CONGRESS ASSET MANAGEMENT CO 0.08% of their portfolio | 93.9k $11.8m | Added +5.9k |
| NORTH STAR ASSET MANAGEMENT INC 0.56% of their portfolio | 93.7k $11.8m | Added +1.5k |
| California Public Employees Retirement System 0.01% of their portfolio | 93.7k $11.8m | Added +17.7k |
| CITIGROUP INC 0.01% of their portfolio | 92.3k $11.6m | Added +61.8k |
| Ensign Peak Advisors, Inc 0.02% of their portfolio | 88.8k $11.2m | Reduced -22.8k |
| Artemis Investment Management LLP 0.15% of their portfolio | 87.8k $11.1m | Reduced -80.0k |
| BARCLAYS PLC 0.01% of their portfolio | 87.2k $11.0m | Reduced -42.4k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.01% of their portfolio | 85.4k $10.8m | Added +3.2k |
| AWM Investment Company, Inc. 1.28% of their portfolio | 75.0k $9.5m | Unchanged |
| W1M Asset Management Ltd 0.79% of their portfolio | 74.1k $9.3m | Added +8.7k |
| UBS Group AG 0.00% of their portfolio | 73.9k $9.3m | Reduced -7.9k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.01% of their portfolio | 67.7k $8.5m | Added +2.9k |
| WCM INVESTMENT MANAGEMENT, LLC 0.02% of their portfolio | 67.0k $8.5m | Reduced -22.6k |
| Corebridge Financial, Inc. 0.05% of their portfolio | 65.9k $8.3m | First filing |
| Pier Capital, LLC 1.22% of their portfolio | 65.1k $8.2m | Added +15.0k |
| Retirement Systems of Alabama 0.03% of their portfolio | 64.1k $8.1m | Reduced -1.1k |
| Alberta Investment Management Corp 0.08% of their portfolio | 63.2k $8.0m | Reduced -1.1k |
| Integral Health Asset Management, LLC 0.75% of their portfolio | 60.0k $7.6m | Added +10.0k |
| BNP PARIBAS FINANCIAL MARKETS 0.01% of their portfolio | 59.1k $7.5m | Reduced -21.3k |
| TD Asset Management Inc 0.01% of their portfolio | 59.0k $7.4m | Added +1.2k |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 0.01% of their portfolio | 58.3k $7.3m | Reduced -5.7k |