RELMADA THERAPEUTICS INC RLMD
COM · Common Stock · CUSIP 75955J402 · ISIN US75955J4022
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersCoral Gables, FL
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Shares outstanding: 106.7m as of 2026-08-04, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $6.92. Options: 5 managers hold calls ($2.1m notional), 2 hold puts ($3.5k).
Trends to Q2 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 135 |
| Q4 2022 | 110 |
| Q1 2023 | 92 |
| Q2 2023 | 96 |
| Q3 2023 | 89 |
| Q4 2023 | 84 |
| Q1 2024 | 94 |
| Q2 2024 | 80 |
| Q3 2024 | 70 |
| Q4 2024 | 49 |
| Q1 2025 | 45 |
| Q2 2025 | 51 |
| Q3 2025 | 44 |
| Q4 2025 | 78 |
| Q1 2026 | 103 |
| Q2 2026 | 126 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2024 | 17 | 40 |
| Q4 2024 | 16 | 48 |
| Q1 2025 | 11 | 26 |
| Q2 2025 | 19 | 20 |
| Q3 2025 | 15 | 20 |
| Q4 2025 | 55 | 8 |
| Q1 2026 | 60 | 35 |
| Q2 2026 | 82 | 45 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2025 | $281.6k | $0 | 0.00 |
| Q4 2025 | $1.9m | $56.5k | 0.03 |
| Q1 2026 | $3.7m | $545.7k | 0.15 |
| Q2 2026 | $2.1m | $3.5k | 0.00 |
Biggest buyers
| BlackRock, Inc. | Added | +6.1m |
| Jones Hill Capital LP | Added | +3.3m |
| STATE STREET CORP | Added | +2.2m |
| Venrock Adviser, LLC | Added | +2.0m |
| GEODE CAPITAL MANAGEMENT, LLC | Added | +1.6m |
| VANGUARD CAPITAL MANAGEMENT LLC | Added | +1.4m |
| Balyasny Asset Management L.P. | Added | +1.3m |
| CITADEL ADVISORS LLC | New | +1.1m |
| EVENTIDE ASSET MANAGEMENT, LLC | Added | +1.0m |
| VANGUARD PORTFOLIO MANAGEMENT LLC | New | +898.2k |
Biggest sellers
| RA CAPITAL MANAGEMENT, L.P. | Sold out | -2.9m |
| MARSHALL WACE, LLP | Reduced | -2.2m |
| MILLENNIUM MANAGEMENT LLC | Reduced | -1.5m |
| Squadron Capital Management LLC | Reduced | -1.1m |
| ORBIMED ADVISORS LLC | Reduced | -1.1m |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | -981.5k |
| Corient Private Wealth LP | Sold out | -719.6k |
| Ikarian Capital, LLC | Reduced | -540.0k |
| Point72 Asset Management, L.P. | Sold out | -504.8k |
| JANE STREET GROUP, LLC | Sold out | -222.0k |
Biggest calls
| CITADEL ADVISORS LLC | Added | $754.3k109.0k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $526.6k76.1k shares |
| SIMPLEX TRADING, LLC | Reduced | $321.8k46.5k shares |
| GROUP ONE TRADING LLC | Reduced | $267.8k38.7k shares |
| Belvedere Trading LLC | New | $187.5k27.1k shares |
Biggest puts
| SIMPLEX TRADING, LLC | Reduced | $2.1k300 shares |
| GROUP ONE TRADING LLC | Reduced | $1.4k200 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| JANUS HENDERSON GROUP PLC 13G · institution new · filed 2026-02-06 | 10.1% |
| Squadron Capital Management LLC 13G · institution -2.9 pts · filed 2026-08-14 | 7.0% |
| BlackRock, Inc. 13G · institution new · filed 2026-07-29 | 7.0% |
| Venrock Healthcare Capital Partners III, L.P. 13G · passive investor new · filed 2026-06-09 | 6.2% |
| Spruce Street Capital LP 13G · institution new · filed 2026-02-17 | 5.6% |
| Commodore Capital LP 13G · passive investor new · filed 2026-05-04 | 5.1% |
Fell to 5% or below in the last year: MILLENNIUM MANAGEMENT LLC (4.4%, 2026-06-22), Adage Capital Management, L.P. (4.5%, 2026-05-13), Ikarian Capital, LLC (4.8%, 2025-11-14)
Insider purchases and sales since 1 Apr 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2024 | 0 | — | 0 | — | — |
| Q1 2025 | 0 | — | 0 | — | — |
| Q2 2025 | 4 | $461.6k | 0 | — | — |
| Q3 2025 | 1 | $178.1k | 0 | — | — |
| Q4 2025 | 4 | $2.4m | 0 | — | — |
| Q1 2026 | 0 | — | 0 | — | — |
| Q2 2026 | 0 | — | 0 | — | — |
| Q3 2026 | 2 | $1.7m | 0 | — | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2026-09-10 | TRAVERSA SERGIO Chief Executive Officer, director | Bought | $410.0k100.0k shares |
| 2026-09-10 | Shenouda Maged Chief Financial Officer | Bought | $339.1k79.8k shares |
| 2026-09-09 | Shenouda Maged Chief Financial Officer | Bought | $504.8k120.2k shares |
| 2026-09-09 | TRAVERSA SERGIO Chief Executive Officer, director | Bought | $418.0k100.0k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2026
| Manager | Shares | Change |
|---|---|---|
| Jupiter Topco LLC 0.03% of their portfolio | 11.2m $77.3m | First filing |
| BlackRock, Inc. 0.00% of their portfolio | 7.4m $51.4m | Added +6.1m |
| Squadron Capital Management LLC 17.41% of their portfolio | 7.3m $50.9m | Reduced -1.1m |
| Venrock Adviser, LLC 1.44% of their portfolio | 6.8m $47.4m | Added +2.0m |
| Spruce Street Capital LP 8.68% of their portfolio | 6.4m $44.2m | Added +129.2k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.05% of their portfolio | 4.8m $33.0m | Unchanged |
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 4.5m $30.9m | Added +1.4m |
| Jones Hill Capital LP 5.38% of their portfolio | 3.7m $25.3m | Added +3.3m |
| ORBIMED ADVISORS LLC 0.48% of their portfolio | 3.6m $25.1m | Reduced -1.1m |
| STATE STREET CORP 0.00% of their portfolio | 2.5m $17.4m | Added +2.2m |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 2.5m $17.3m | Added +1.6m |
| MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio | 2.4m $16.3m | Reduced -1.5m |
| MARSHALL WACE, LLP 0.01% of their portfolio | 2.2m $15.5m | Reduced -2.2m |
| Ikarian Capital, LLC 2.43% of their portfolio | 2.1m $14.9m | Reduced -540.0k |
| Driehaus Capital Management LLC 0.09% of their portfolio | 2.1m $14.8m | Unchanged |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 1.9m $13.4m | Added +347.0k |
| EVENTIDE ASSET MANAGEMENT, LLC 0.17% of their portfolio | 1.9m $12.9m | Added +1.0m |
| Balyasny Asset Management L.P. 0.02% of their portfolio | 1.5m $10.5m | Added +1.3m |
| STEMPOINT CAPITAL LP 1.75% of their portfolio | 1.5m $10.1m | Added +265.3k |
| Commodore Capital LP 0.59% of their portfolio | 1.4m $9.9m | Added +791.1k |
| Polar Capital Holdings Plc 0.03% of their portfolio | 1.3m $9.3m | Reduced -74.2k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 1.1m $7.3m | New |
| Sio Capital Management, LLC 1.19% of their portfolio | 1.0m $6.9m | Added +38.6k |
| Opaleye Management Inc. 0.59% of their portfolio | 935.0k $6.5m | Unchanged |
| VANGUARD PORTFOLIO MANAGEMENT LLC 0.00% of their portfolio | 898.2k $6.2m | New |
| GREAT POINT PARTNERS LLC 1.37% of their portfolio | 842.1k $5.8m | Unchanged |
| Soleus Capital Management, L.P. 0.20% of their portfolio | 842.1k $5.8m | Unchanged |
| Boxer Capital Management, LLC 0.44% of their portfolio | 842.1k $5.8m | Unchanged |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 812.1k $5.6m | Added +686.1k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 786.3k $5.4m | Added +628.5k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 767.6k $5.3m | Added +68.6k |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 734.2k $5.1m | Added +284.4k |
| Qube Research & Technologies Ltd 0.01% of their portfolio | 691.5k $4.8m | Added +38.2k |
| Walleye Capital LLC 0.02% of their portfolio | 616.2k $4.3m | New |
| BOOTHBAY FUND MANAGEMENT, LLC 0.07% of their portfolio | 564.8k $3.9m | Reduced -164.3k |
| ACADIAN ASSET MANAGEMENT LLC 0.00% of their portfolio | 543.4k $3.8m | Reduced -169.1k |
| Integral Health Asset Management, LLC 0.14% of their portfolio | 500.0k $3.5m | Added +50.0k |
| ADAR1 Capital Management, LLC 0.15% of their portfolio | 451.9k $3.1m | Unchanged |
| Knott David M Jr 1.65% of their portfolio | 451.0k $3.1m | Added +11.7k |
| HighVista Strategies LLC 0.70% of their portfolio | 445.8k $3.1m | New |
| AdvisorShares Investments LLC 0.37% of their portfolio | 438.9k $3.0m | Added +143.0k |
| Birchview Capital, LP 1.32% of their portfolio | 408.1k $2.8m | Reduced -1.3k |
| DIADEMA PARTNERS LP 0.88% of their portfolio | 361.4k $2.5m | Added +160.5k |
| PARSONS CAPITAL MANAGEMENT INC/RI 0.11% of their portfolio | 354.1k $2.5m | Added +1.6k |
| Seven Fleet Capital Management LP 0.40% of their portfolio | 348.3k $2.4m | New |
| Harvest Investment Services, LLC 0.36% of their portfolio | 340.9k $2.4m | New |
| Woodline Partners LP 0.01% of their portfolio | 328.4k $2.3m | Reduced -92.6k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 318.9k $2.2m | Added +94.1k |
| SEVEN GRAND MANAGERS, LLC 0.09% of their portfolio | 315.8k $2.2m | Unchanged |
| Bank of New York Mellon Corp 0.00% of their portfolio | 295.6k $2.0m | New |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 282.7k $2.0m | Added +229.6k |
| Nuveen, LLC 0.00% of their portfolio | 225.1k $1.6m | New |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 214.9k $1.5m | Reduced -193.2k |
| UBS Group AG 0.00% of their portfolio | 158.0k $1.1m | Added +31.4k |
| LOS ANGELES CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 155.7k $1.1m | New |
| GSA CAPITAL PARTNERS LLP 0.06% of their portfolio | 141.4k $979.0k | Added +121.9k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 118.1k $817.3k | New |
| D. E. Shaw & Co., Inc. 0.00% of their portfolio | 109.5k $757.6k | New |
| ALPS ADVISORS INC 0.00% of their portfolio | 106.5k $736.7k | New |
| X-Square Capital, LLC 0.18% of their portfolio | 100.0k $692.0k | New |
| MGO ONE SEVEN LLC 0.01% of their portfolio | 100.0k $692.0k | Unchanged |
| Eversept Partners, LP 0.04% of their portfolio | 93.2k $644.9k | Reduced -184.7k |
| Invesco Ltd. 0.00% of their portfolio | 89.7k $620.5k | Added +67.2k |
| Informed Momentum Co LLC 0.05% of their portfolio | 88.4k $612.1k | Reduced -42.5k |
| Verdad Advisers, LP 0.58% of their portfolio | 87.0k $602.0k | Added +39.8k |
| Persistent Asset Partners Ltd 0.19% of their portfolio | 86.4k $598.2k | Added +35.7k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 86.3k $596.9k | New |
| MORGAN STANLEY 0.00% of their portfolio | 82.8k $573.1k | Reduced -115.6k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 77.7k $538.0k | New |
| CITIGROUP INC 0.00% of their portfolio | 71.8k $496.5k | Added +56.3k |
| MANGROVE PARTNERS IM, LLC 0.03% of their portfolio | 71.7k $496.2k | Unchanged |
| SEI INVESTMENTS CO 0.00% of their portfolio | 69.4k $480.1k | Reduced -97.2k |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 67.3k $466.0k | New |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 63.8k $441.5k | New |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 57.8k $400.0k | Reduced -109.4k |
| LMR Partners LLP 0.00% of their portfolio | 55.6k $384.8k | Reduced -8.0k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 55.6k $384.5k | New |
| BARCLAYS PLC 0.00% of their portfolio | 51.2k $354.5k | Reduced -37.7k |
| Virtus Investment Advisers, LLC 0.08% of their portfolio | 49.2k $340.5k | New |
| LPL Financial LLC 0.00% of their portfolio | 48.6k $336.1k | New |
| apricus wealth, LLC 0.16% of their portfolio | 47.5k $328.4k | Unchanged |
| Vanguard Global Advisers, LLC 0.00% of their portfolio | 44.2k $305.6k | Added +15.0k |
| Trexquant Investment LP 0.00% of their portfolio | 43.7k $302.7k | New |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 43.4k $300.1k | New |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 39.6k $275.6k | New |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 39.2k $273.6k | New |
| AlTi Global, Inc. 0.00% of their portfolio | 32.0k $221.3k | Unchanged |
| Pale Fire Capital SE 0.02% of their portfolio | 31.6k $219.0k | Unchanged |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 30.1k $208.3k | Reduced -981.5k |
| Police & Firemen's Retirement System of New Jersey 0.00% of their portfolio | 27.9k $193.0k | New |
| PROFUND ADVISORS LLC 0.01% of their portfolio | 27.3k $189.1k | New |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 26.0k $179.9k | New |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 25.0k $173.2k | New |
| Robertson Stephens Wealth Management, LLC 0.00% of their portfolio | 25.0k $173.0k | Unchanged |
| State of Wyoming 0.01% of their portfolio | 20.6k $142.5k | Added +8.0k |
| Rafferty Asset Management, LLC 0.00% of their portfolio | 19.9k $137.7k | New |
| INTECH INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 19.7k $136.5k | New |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 17.9k $124.1k | New |
| PRUDENTIAL FINANCIAL INC 0.00% of their portfolio | 16.0k $110.9k | New |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 14.4k $99.8k | Added +6.1k |