RELAY THERAPEUTICS INC RLAY
COM · Common Stock · CUSIP 75943R102
Company in Cambridge, United States
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersCambridge, MA
- Founded2016
- Websiterelaytx.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($2.8m this quarter). Holder counts are more reliable. Shares outstanding: 121.6m as of 2023-04-28, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $16.46. Options: 9 managers hold calls ($5.1m notional), 8 hold puts ($4.4m).
Trends to Q1 2023
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 162 |
| Q4 2022 | 165 |
| Q1 2023 | 158 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 95 | 64 |
| Q1 2023 | 75 | 79 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2022 | $7.2m | $1.8m | 0.25 |
| Q4 2022 | $1.7m | $3.0k | 0.00 |
| Q1 2023 | $5.1m | $4.4m | 0.85 |
Biggest buyers
| FMR LLC | Added | +7.9m |
| Casdin Capital, LLC | Added | +2.7m |
| PRICE T ROWE ASSOCIATES INC /MD/ | Added | +2.4m |
| MPM BIOIMPACT LLC | New | +1.2m |
| GREAT POINT PARTNERS LLC | New | +658.1k |
| BAKER BROS. ADVISORS LP | New | +284.0k |
| BANK OF AMERICA CORP /DE/ | Added | +271.4k |
| Sio Capital Management, LLC | New | +230.0k |
| Artal Group S.A. | Added | +219.0k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | +218.8k |
Biggest sellers
| MORGAN STANLEY | Reduced | -1.8m |
| BVF INC/IL | Reduced | -755.5k |
| MILLENNIUM MANAGEMENT LLC | Sold out | -575.1k |
| STATE STREET CORP | Reduced | -384.2k |
| Sessa Capital IM, L.P. | Sold out | -301.2k |
| Ghisallo Capital Management LLC | Sold out | -274.8k |
| ALLIANCEBERNSTEIN L.P. | Reduced | -204.1k |
| Balyasny Asset Management L.P. | Sold out | -203.2k |
| WELLINGTON MANAGEMENT GROUP LLP | Reduced | -200.9k |
| NORGES BANK | Reduced | -174.5k |
Biggest calls
| MILLENNIUM MANAGEMENT LLC | Added | $3.1m190.0k shares |
| Ratan Capital Management LP | New | $667.0k40.5k shares |
| CITADEL ADVISORS LLC | Added | $413.4k25.1k shares |
| Belvedere Trading LLC | New | $298.1k18.1k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $253.6k15.4k shares |
| Jefferies Financial Group Inc. | New | $238.8k14.5k shares |
| JPMORGAN CHASE & CO | New | $99.0k6.0k shares |
| GROUP ONE TRADING LLC | New | $21.4k1.3k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | New | $1.8m108.4k shares |
| CITADEL ADVISORS LLC | Added | $1.1m68.9k shares |
| JPMORGAN CHASE & CO | New | $721.0k43.8k shares |
| Jefferies Financial Group Inc. | New | $558.3k33.9k shares |
| SIMPLEX TRADING, LLC | New | $100.0k6.1k shares |
| Belvedere Trading LLC | New | $32.9k2.0k shares |
| GROUP ONE TRADING LLC | New | $18.1k1.1k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| FMR LLC 13G · institution +0.6 pts · filed 2026-08-07 | 10.0% |
| Casdin Capital, LLC 13G · passive investor no change · filed 2026-02-17 | 7.5% |
| PERCEPTIVE ADVISORS LLC 13G · passive investor +1.1 pts · filed 2026-08-10 | 6.4% |
| BlackRock, Inc. 13G · institution -2.7 pts · filed 2025-04-17 | 6.1% |
| Commodore Capital LP 13G · passive investor -4.4 pts · filed 2026-08-14 | 5.5% |
Fell to 5% or below in the last year: Point72 Asset Management, L.P. (0.0%, 2026-05-15), VANGUARD GROUP INC (0.0%, 2026-03-27)
Insider purchases and sales in Q1 2023
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q2 2021 | 0 | — | 0 | — | — |
| Q3 2021 | 0 | — | 0 | — | — |
| Q4 2021 | 0 | — | 4 | $2.1m | — |
| Q1 2022 | 0 | — | 4 | $1.7m | — |
| Q2 2022 | 0 | — | 5 | $3.8m | — |
| Q3 2022 | 0 | — | 6 | $4.4m | — |
| Q4 2022 | 0 | — | 5 | $2.2m | — |
| Q1 2023 | 0 | — | 5 | $2.9m | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2023-03-27 | Bergstrom Donald A President, R&D | Sold | $11.7k763 shares |
| 2023-03-27 | Adams Brian Chief Legal Officer | Sold | $5.3k347 shares |
| 2023-03-27 | Catinazzo Thomas Chief Financial Officer | Sold | $5.3k347 shares |
| 2023-03-27 | Rahmer Peter Officer | Sold | $4.6k297 shares |
| 2023-02-09 | Patel Sanjiv President and CEO, director | Sold | $287.7k14.0k shares |
| 2023-02-08 | Patel Sanjiv President and CEO, director | Sold | $293.7k14.0k shares |
| 2023-02-07 | Patel Sanjiv President and CEO, director | Sold | $300.3k14.0k shares |
| 2023-01-30 | Bergstrom Donald A President, R&D | Sold | $30.8k1.4k shares |
| 2023-01-30 | Adams Brian Chief Legal Officer | Sold | $18.6k864 shares |
| 2023-01-30 | Catinazzo Thomas Chief Financial Officer | Sold | $18.6k864 shares |
| 2023-01-30 | Rahmer Peter Officer | Sold | $16.0k740 shares |
| 2023-01-19 | Patel Sanjiv President and CEO, director | Sold | $560.6k28.0k shares |
| 2023-01-18 | Patel Sanjiv President and CEO, director | Sold | $584.4k28.0k shares |
| 2023-01-17 | Patel Sanjiv President and CEO, director | Sold | $566.4k28.0k shares |
| 2023-01-12 | Adams Brian Chief Legal Officer | Sold | $199.9k10.0k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q1 2023
| Manager | Shares | Change |
|---|---|---|
| SB INVESTMENT ADVISERS (UK) LTD 3.78% of their portfolio | 27.9m $459.6m | Unchanged |
| FMR LLC 0.01% of their portfolio | 17.6m $290.1m | Added +7.9m |
| VANGUARD GROUP INC 0.00% of their portfolio | 10.5m $172.9m | Added +115.3k |
| BlackRock Inc. 0.00% of their portfolio | 7.9m $130.7m | Reduced -62.3k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.02% of their portfolio | 6.9m $113.0m | Added +2.4m |
| STATE STREET CORP 0.01% of their portfolio | 5.9m $96.8m | Reduced -384.2k |
| Casdin Capital, LLC 7.75% of their portfolio | 5.7m $93.9m | Added +2.7m |
| JPMORGAN CHASE & CO 0.01% of their portfolio | 4.3m $70.8m | Reduced -169.1k |
| Bellevue Group AG 1.00% of their portfolio | 4.2m $68.7m | Reduced -32.2k |
| EcoR1 Capital, LLC 2.21% of their portfolio | 4.2m $68.6m | Unchanged |
| BVF INC/IL 1.88% of their portfolio | 3.1m $51.4m | Reduced -755.5k |
| ArrowMark Colorado Holdings LLC 0.50% of their portfolio | 2.7m $44.0m | Reduced -16.5k |
| T. Rowe Price Investment Management, Inc. 0.03% of their portfolio | 2.2m $36.6m | Added +215.0k |
| Boxer Capital, LLC 1.76% of their portfolio | 2.2m $35.7m | Unchanged |
| PERCEPTIVE ADVISORS LLC 0.95% of their portfolio | 1.9m $32.0m | Unchanged |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 1.8m $28.9m | Added +60.4k |
| Artal Group S.A. 1.64% of their portfolio | 1.7m $27.6m | Added +219.0k |
| NORGES BANK 0.01% of their portfolio | 1.6m $26.6m | Reduced -174.5k |
| Driehaus Capital Management LLC 0.37% of their portfolio | 1.6m $26.1m | Reduced -36.1k |
| Alphabet Inc. 1.43% of their portfolio | 1.6m $25.8m | Unchanged |
| ALLIANCEBERNSTEIN L.P. 0.01% of their portfolio | 1.5m $24.5m | Reduced -204.1k |
| GOLDMAN SACHS GROUP INC 0.01% of their portfolio | 1.4m $23.0m | Added +125.7k |
| Candriam S.C.A. 0.13% of their portfolio | 1.2m $18.8m | Unchanged |
| DIMENSIONAL FUND ADVISORS LP 0.01% of their portfolio | 1.2m $20.4m | Added +177.3k |
| MPM BIOIMPACT LLC 5.24% of their portfolio | 1.2m $20.2m | New |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.01% of their portfolio | 886.5k $14.6m | Added +70.5k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 872.4k $14.4m | Reduced -9.9k |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 850.5k $14.0m | Reduced -200.9k |
| Finepoint Capital LP 5.32% of their portfolio | 846.3k $13.9m | Added +131.4k |
| Integral Health Asset Management, LLC 2.63% of their portfolio | 770.0k $12.7m | Added +145.0k |
| Rock Springs Capital Management LP 0.27% of their portfolio | 674.0k $11.1m | Unchanged |
| GREAT POINT PARTNERS LLC 2.14% of their portfolio | 658.1k $10.8m | New |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 653.9k $10.8m | Reduced -561 |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 625.9k $10.3m | Added +271.4k |
| Nextech Invest Ltd. 4.30% of their portfolio | 625.5k $10.3m | Added +150.0k |
| BESSEMER GROUP INC 0.02% of their portfolio | 584.5k $9.6m | Unchanged |
| MORGAN STANLEY 0.00% of their portfolio | 562.1k $9.3m | Reduced -1.8m |
| HARVARD MANAGEMENT CO INC 0.94% of their portfolio | 541.1k $8.9m | Unchanged |
| Rafferty Asset Management, LLC 0.05% of their portfolio | 443.6k $7.3m | Reduced -30.7k |
| BAILLIE GIFFORD & CO 0.01% of their portfolio | 415.7k $6.8m | Added +1.1k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 376.0k $6.2m | Reduced -12.5k |
| CITIGROUP INC 0.01% of their portfolio | 356.1k $5.9m | Added +146.9k |
| HarbourVest Partners LLC 1.64% of their portfolio | 296.4k $4.9m | Unchanged |
| Artisan Partners Limited Partnership 0.01% of their portfolio | 294.7k $4.9m | Reduced -728 |
| BAKER BROS. ADVISORS LP 0.03% of their portfolio | 284.0k $4.7m | New |
| Woodline Partners LP 0.06% of their portfolio | 275.0k $4.5m | Reduced -56.7k |
| SCHRODER INVESTMENT MANAGEMENT GROUP 0.01% of their portfolio | 268.1k $4.4m | Added +29.9k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.01% of their portfolio | 254.9k $4.2m | Added +218.8k |
| Nuveen Asset Management, LLC 0.00% of their portfolio | 250.9k $4.1m | Added +15.7k |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 240.4k $4.0m | Added +21.0k |
| Sio Capital Management, LLC 1.87% of their portfolio | 230.0k $3.8m | New |
| TD Asset Management Inc 0.00% of their portfolio | 216.8k $3.6m | Added +93.3k |
| BARCLAYS PLC 0.00% of their portfolio | 194.5k $3.2m | Reduced -77.4k |
| Rhenman & Partners Asset Management AB 0.33% of their portfolio | 190.0k $3.0m | Reduced -10.0k |
| Fernwood Investment Management, LLC 1.17% of their portfolio | 185.1k $3.0m | Unchanged |
| UBS Group AG 0.00% of their portfolio | 170.7k $2.8m | Reduced -92.4k |
| Swiss National Bank 0.00% of their portfolio | 169.7k $2.8m | Reduced -19.0k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 168.2k $2.8m | Added +61.8k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 157.3k $2.6m | Reduced -79.6k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 135.6k $2.2m | Added +6.7k |
| State of New Jersey Common Pension Fund D 0.01% of their portfolio | 131.2k $2.2m | Added +6.7k |
| HighVista Strategies LLC 1.73% of their portfolio | 129.2k $2.1m | Reduced -47.3k |
| Jefferies Financial Group Inc. 0.04% of their portfolio | 127.3k $2.1m | New |
| Opaleye Management Inc. 0.62% of their portfolio | 125.5k $2.1m | New |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 118.9k $2.0m | Added +58.1k |
| Industrial Alliance Investment Management Inc. 0.05% of their portfolio | 110.6k $1.8m | New |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 104.4k $1.7m | Added +19.9k |
| GILDER GAGNON HOWE & CO LLC 0.03% of their portfolio | 102.6k $1.7m | Reduced -5.4k |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 102.2k $1.7m | Unchanged |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 100.7k $1.7m | Reduced -1.3k |
| TWINBEECH CAPITAL LP 0.03% of their portfolio | 98.6k $1.6m | Reduced -105.8k |
| ICONIQ Capital, LLC 0.02% of their portfolio | 94.7k $1.6m | Unchanged |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 89.7k $1.5m | Added +88.8k |
| PROFUND ADVISORS LLC 0.08% of their portfolio | 82.3k $1.4m | New |
| CREDIT SUISSE AG/ 0.00% of their portfolio | 81.5k $1.3m | Added +5.3k |
| Legal & General Group Plc 0.00% of their portfolio | 75.1k $1.2m | Added +12.7k |
| CANADA PENSION PLAN INVESTMENT BOARD 0.00% of their portfolio | 74.5k $1.2m | New |
| Invesco Ltd. 0.00% of their portfolio | 74.0k $1.2m | Added +15.1k |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 72.5k $1.2m | Reduced -3.7k |
| DekaBank Deutsche Girozentrale 0.00% of their portfolio | 60.0k $955.0k | Added +29.9k |
| BIT Capital GmbH 0.15% of their portfolio | 58.8k $967.8k | Added +20.0k |
| Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio | 56.8k $935.6k | Added +16.7k |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 55.9k $920.9k | Reduced -12.4k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 45.6k $750.9k | Added +33.6k |
| MetLife Investment Management, LLC 0.01% of their portfolio | 44.6k $735.1k | Unchanged |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) 0.02% of their portfolio | 44.1k $726.3k | New |
| AMERICAN INTERNATIONAL GROUP, INC. 0.00% of their portfolio | 41.1k $676.6k | Added +818 |
| Qube Research & Technologies Ltd 0.00% of their portfolio | 40.1k $660.1k | Reduced -2.5k |
| Ensign Peak Advisors, Inc 0.00% of their portfolio | 38.9k $640.7k | New |
| JANUS HENDERSON GROUP PLC 0.00% of their portfolio | 37.4k $616.9k | Added +19.1k |
| Blackstone Inc. 0.00% of their portfolio | 35.6k $586.6k | Unchanged |
| ALGERT GLOBAL LLC 0.03% of their portfolio | 34.2k $563.5k | Reduced -41.5k |
| BRANDYWINE MANAGERS, LLC 0.37% of their portfolio | 31.8k $523.9k | Unchanged |
| Bayesian Capital Management, LP 0.06% of their portfolio | 30.5k $502.3k | New |
| Capula Management Ltd 0.04% of their portfolio | 30.4k $500.4k | Not comparable |
| Fiduciary Trust Co 0.01% of their portfolio | 28.0k $460.7k | Unchanged |
| M&T Bank Corp 0.00% of their portfolio | 27.4k $451.6k | Unchanged |
| Intellectus Partners, LLC 0.14% of their portfolio | 26.9k $442.8k | Reduced -1.9k |
| PRINCIPAL FINANCIAL GROUP INC 0.00% of their portfolio | 26.7k $439.9k | Added +3.0k |
| Caption Management, LLC 0.09% of their portfolio | 25.5k $419.8k | New |