REGENXBIO INC RGNX
COM · Common Stock · CUSIP 75901B107 · ISIN US75901B1070
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersRockville, MD
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($269.8k this quarter). Holder counts are more reliable. Shares outstanding: 66.0m as of 2026-07-31, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $11.96. Options: 9 managers hold calls ($7.1m notional), 6 hold puts ($2.1m).
Trends to Q2 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 183 |
| Q4 2022 | 182 |
| Q1 2023 | 175 |
| Q2 2023 | 168 |
| Q3 2023 | 161 |
| Q4 2023 | 172 |
| Q1 2024 | 189 |
| Q2 2024 | 182 |
| Q3 2024 | 187 |
| Q4 2024 | 178 |
| Q1 2025 | 165 |
| Q2 2025 | 160 |
| Q3 2025 | 166 |
| Q4 2025 | 174 |
| Q1 2026 | 178 |
| Q2 2026 | 165 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2024 | 93 | 73 |
| Q4 2024 | 87 | 94 |
| Q1 2025 | 83 | 94 |
| Q2 2025 | 83 | 79 |
| Q3 2025 | 86 | 67 |
| Q4 2025 | 84 | 74 |
| Q1 2026 | 88 | 85 |
| Q2 2026 | 86 | 87 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2025 | $1.5m | $1.6m | 1.08 |
| Q4 2025 | $2.8m | $2.6m | 0.93 |
| Q1 2026 | $3.8m | $2.4m | 0.63 |
| Q2 2026 | $7.1m | $2.1m | 0.29 |
Biggest buyers
| MARSHALL WACE, LLP | New | +1.3m |
| CITADEL ADVISORS LLC | New | +669.0k |
| BlackRock, Inc. | Added | +614.6k |
| D. E. Shaw & Co., Inc. | Added | +426.8k |
| LAZARD ASSET MANAGEMENT LLC | New | +370.4k |
| VANGUARD PORTFOLIO MANAGEMENT LLC | Added | +336.7k |
| AQR CAPITAL MANAGEMENT LLC | Added | +326.6k |
| Quantinno Capital Management LP | Added | +256.2k |
| STATE STREET CORP | Added | +239.7k |
| Corient Private Wealth LP | New | +217.7k |
Biggest sellers
| Qube Research & Technologies Ltd | Sold out | -1.3m |
| JPMORGAN CHASE & CO | Reduced | -1.3m |
| Integral Health Asset Management, LLC | Reduced | -700.0k |
| Assenagon Asset Management S.A. | Reduced | -642.1k |
| GOLDMAN SACHS GROUP INC | Reduced | -418.0k |
| HRT FINANCIAL LP | Sold out | -351.5k |
| Voss Capital, LP | Sold out | -295.8k |
| DIMENSIONAL FUND ADVISORS LP | Reduced | -278.8k |
| Prosight Management, LP | Sold out | -200.0k |
| Man Group plc | Sold out | -187.6k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $2.7m222.8k shares |
| Centiva Capital, LP | Unchanged | $1.2m100.0k shares |
| Caption Management, LLC | New | $1.2m100.0k shares |
| SIMPLEX TRADING, LLC | Added | $648.1k54.1k shares |
| CITADEL ADVISORS LLC | Added | $554.7k46.3k shares |
| CITIGROUP INC | Reduced | $269.6k22.5k shares |
| JANE STREET GROUP, LLC | Reduced | $256.4k21.4k shares |
| GROUP ONE TRADING LLC | Added | $219.2k18.3k shares |
| LPL Financial LLC | New | $119.8k10.0k shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $1.1m91.7k shares |
| CITADEL ADVISORS LLC | Added | $474.4k39.6k shares |
| CITIGROUP INC | Reduced | $269.6k22.5k shares |
| JANE STREET GROUP, LLC | Reduced | $220.4k18.4k shares |
| SIMPLEX TRADING, LLC | Added | $19.2k1.6k shares |
| GROUP ONE TRADING LLC | New | $1.2k100 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| Redmile Group, LLC 13G · passive investor filed 2025-08-14 | 9.9% |
| BlackRock, Inc. 13G · institution -3.7 pts · filed 2025-04-24 | 7.3% |
| JPMORGAN CHASE & CO 13G · institution +0.9 pts · filed 2026-10-13 | 5.3% |
| STATE STREET CORP 13G · institution +0.9 pts · filed 2026-05-12 | 5.3% |
Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-27), BlackRock Portfolio Management LLC (4.1%, 2026-01-21; now reported by BlackRock, Inc.)
Insider purchases and sales since 1 Apr 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2024 | 0 | — | 1 | $101.1k | $101.1k |
| Q1 2025 | 0 | — | 0 | — | — |
| Q2 2025 | 0 | — | 1 | $163.0k | $163.0k |
| Q3 2025 | 0 | — | 1 | $154.0k | $154.0k |
| Q4 2025 | 0 | — | 1 | $262.6k | $262.6k |
| Q1 2026 | 0 | — | 1 | $53.0k | $53.0k |
| Q2 2026 | 0 | — | 1 | $385.2k | $168.7k |
| Q3 2026 | 1 | $949.5k | 1 | $501.8k | $29.5k |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2026-08-27 | Ciongoli Gregory Austin Director | Bought | $499.9k53.4k shares |
| 2026-08-26 | Ciongoli Gregory Austin Director | Bought | $449.7k49.2k shares |
| 2026-07-02 | PAKOLA STEVE Chief Medical Officer | Sold plan | $29.5k2.2k shares |
| 2026-07-01 | PAKOLA STEVE Chief Medical Officer | Sold | $472.3k36.7k shares |
| 2026-06-29 | PAKOLA STEVE Chief Medical Officer | Sold | $216.5k19.6k shares |
| 2026-05-11 | PAKOLA STEVE Chief Medical Officer | Sold plan | $168.7k15.3k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2026
| Manager | Shares | Change |
|---|---|---|
| BlackRock, Inc. 0.00% of their portfolio | 6.4m $76.6m | Added +614.6k |
| Redmile Group, LLC 3.51% of their portfolio | 4.4m $52.3m | Unchanged |
| STATE STREET CORP 0.00% of their portfolio | 3.0m $35.6m | Added +239.7k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 2.2m $26.2m | Reduced -1.3m |
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 2.1m $25.2m | Added +100.4k |
| MORGAN STANLEY 0.00% of their portfolio | 2.0m $23.4m | Reduced -112.9k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 1.4m $17.0m | Reduced -418.0k |
| AQR CAPITAL MANAGEMENT LLC 0.01% of their portfolio | 1.4m $16.5m | Added +326.6k |
| VANGUARD PORTFOLIO MANAGEMENT LLC 0.00% of their portfolio | 1.4m $16.2m | Added +336.7k |
| MARSHALL WACE, LLP 0.01% of their portfolio | 1.3m $15.4m | New |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 1.2m $14.9m | Added +103.8k |
| Integral Health Asset Management, LLC 0.39% of their portfolio | 800.0k $9.6m | Reduced -700.0k |
| Nuveen, LLC 0.00% of their portfolio | 740.0k $8.9m | Added +158.0k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 731.6k $8.8m | Reduced -278.8k |
| D. E. Shaw & Co., Inc. 0.01% of their portfolio | 712.8k $8.5m | Added +426.8k |
| TWO SIGMA INVESTMENTS, LP 0.01% of their portfolio | 669.8k $8.0m | Added +114.9k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 669.0k $8.0m | New |
| STIFEL FINANCIAL CORP 0.01% of their portfolio | 560.7k $6.7m | Added +168.0k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 518.5k $6.2m | Added +193.7k |
| 22NW, LP 5.64% of their portfolio | 492.8k $5.9m | Unchanged |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 480.8k $5.8m | Added +195.6k |
| Pale Fire Capital SE 0.40% of their portfolio | 466.2k $5.6m | Reduced -27.5k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 421.8k $5.1m | Added +28.2k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 396.4k $4.7m | Added +5.8k |
| LAZARD ASSET MANAGEMENT LLC 0.01% of their portfolio | 370.4k $4.4m | New |
| FMR LLC 0.00% of their portfolio | 342.9k $4.1m | Added +31.6k |
| Assenagon Asset Management S.A. 0.00% of their portfolio | 338.6k $4.1m | Reduced -642.1k |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 337.2k $4.0m | Added +25.1k |
| Quantinno Capital Management LP 0.00% of their portfolio | 300.1k $3.6m | Added +256.2k |
| GSK plc 0.54% of their portfolio | 271.5k $3.3m | Unchanged |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 264.9k $3.2m | Added +173.8k |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 256.7k $3.1m | Reduced -48.6k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 253.5k $3.0m | Added +147.9k |
| UBS Group AG 0.00% of their portfolio | 249.9k $3.0m | Reduced -7.5k |
| Jump Financial, LLC 0.03% of their portfolio | 239.7k $2.9m | Added +18.9k |
| Hudson Bay Capital Management LP 0.01% of their portfolio | 225.0k $2.7m | Added +45.0k |
| ArchPoint Investors 0.56% of their portfolio | 222.3k $2.7m | Unchanged |
| Corient Private Wealth LP 0.00% of their portfolio | 217.7k $2.6m | New |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 207.8k $2.5m | Added +10.9k |
| Walleye Capital LLC 0.01% of their portfolio | 203.7k $2.4m | New |
| Y-Intercept (Hong Kong) Ltd 0.04% of their portfolio | 181.5k $2.2m | Reduced -93.5k |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. 0.00% of their portfolio | 149.0k $1.8m | Unchanged |
| IEQ CAPITAL, LLC 0.01% of their portfolio | 141.5k $1.7m | Added +1.8k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 134.2k $1.6m | Reduced -6.0k |
| Invesco Ltd. 0.00% of their portfolio | 133.9k $1.6m | Reduced -25.0k |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 121.4k $1.5m | Added +7.9k |
| Susquehanna Portfolio Strategies, LLC 0.02% of their portfolio | 119.5k $1.4m | Reduced -67.1k |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ 0.00% of their portfolio | 107.7k $1.3m | Reduced -4.3k |
| XTX Topco Ltd 0.02% of their portfolio | 107.3k $1.3m | Added +73.4k |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 100.1k $1.2m | Reduced -100.3k |
| RAYMOND JAMES FINANCIAL INC 0.00% of their portfolio | 92.6k $1.1m | Reduced -8.7k |
| SCHRODER INVESTMENT MANAGEMENT GROUP 0.00% of their portfolio | 91.5k $1.1m | New |
| Trexquant Investment LP 0.01% of their portfolio | 86.4k $1.0m | New |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 78.4k $937.9k | Added +20.0k |
| CITIGROUP INC 0.00% of their portfolio | 78.0k $934.7k | Added +52.4k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 77.9k $932.7k | Added +27.4k |
| DekaBank Deutsche Girozentrale 0.00% of their portfolio | 74.6k $577.0k | Unchanged |
| Balyasny Asset Management L.P. 0.00% of their portfolio | 74.0k $887.1k | Added +62.4k |
| ACT CAPITAL MANAGEMENT, LLC 0.53% of their portfolio | 67.5k $808.6k | Added +11.5k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 63.1k $757.0k | Added +12.0k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 61.3k $513.9k | Reduced -3.4k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 59.8k $716.2k | Reduced -704 |
| Rafferty Asset Management, LLC 0.00% of their portfolio | 54.5k $652.3k | Reduced -19.4k |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 51.5k $617.6k | Added +29.8k |
| SIMPLEX TRADING, LLC 0.02% of their portfolio | 49.2k $589.9k | New |
| Virtus Investment Advisers, LLC 0.14% of their portfolio | 49.1k $588.6k | Added +29.5k |
| NewEdge Wealth, LLC 0.01% of their portfolio | 47.7k $571.4k | New |
| Cerity Partners LLC 0.00% of their portfolio | 47.6k $570.8k | Reduced -10.7k |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC 0.00% of their portfolio | 45.1k $629.0k | Added +630 |
| BARCLAYS PLC 0.00% of their portfolio | 44.1k $527.9k | Reduced -23.4k |
| Aquatic Capital Management LLC 0.02% of their portfolio | 44.0k $527.1k | New |
| ALGERT GLOBAL LLC 0.01% of their portfolio | 41.1k $491.9k | Added +17.2k |
| Voleon Capital Management LP 0.01% of their portfolio | 40.5k $485.8k | Reduced -1.6k |
| FRANKLIN RESOURCES INC 0.00% of their portfolio | 38.7k $463.4k | Added +21.9k |
| Mariner, LLC 0.00% of their portfolio | 38.2k $457.2k | Added +163 |
| Connor, Clark & Lunn Investment Management Ltd. 0.00% of their portfolio | 37.7k $451.1k | Reduced -47.6k |
| HSBC HOLDINGS PLC 0.00% of their portfolio | 36.4k $437.6k | Reduced -19.4k |
| Engineers Gate Manager LP 0.01% of their portfolio | 34.4k $412.1k | Reduced -29.3k |
| HARBOR CAPITAL ADVISORS, INC. 0.03% of their portfolio | 33.9k $406.0k | Reduced -14.6k |
| Brevan Howard Capital Management LP 0.01% of their portfolio | 33.2k $397.5k | Added +14.3k |
| Rockefeller Capital Management L.P. 0.00% of their portfolio | 31.5k $377.4k | Unchanged |
| MERCER GLOBAL ADVISORS INC /ADV 0.00% of their portfolio | 31.4k $376.7k | Added +7.6k |
| Palogic Value Management, L.P. 0.13% of their portfolio | 30.0k $359.9k | Added +40 |
| CANADA LIFE ASSURANCE Co 0.00% of their portfolio | 27.6k $330.0k | Reduced -704 |
| PROFUND ADVISORS LLC 0.01% of their portfolio | 27.5k $329.3k | Reduced -5.6k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 27.3k $326.5k | Added +7.2k |
| SG Americas Securities, LLC 0.00% of their portfolio | 27.2k $326.0k | Added +7.4k |
| Lion Point Capital, LP 1.52% of their portfolio | 26.6k $318.7k | Unchanged |
| WINTON GROUP Ltd 0.01% of their portfolio | 24.2k $289.9k | New |
| TUDOR INVESTMENT CORP ET AL 0.00% of their portfolio | 23.9k $285.8k | Reduced -456 |
| INCEPTIONR LLC 0.07% of their portfolio | 23.6k $282.8k | Added +13.4k |
| GSA CAPITAL PARTNERS LLP 0.02% of their portfolio | 22.6k $271.0k | New |
| PEAK6 LLC 0.01% of their portfolio | 22.0k $263.6k | New |
| Creative Planning 0.00% of their portfolio | 20.8k $249.0k | Reduced -9.2k |
| DNB Asset Management AS 0.00% of their portfolio | 19.4k $232.0k | Reduced -961 |
| Arax Advisory Partners 0.00% of their portfolio | 19.3k $230.7k | Added +18.5k |
| Vanguard Global Advisers, LLC 0.00% of their portfolio | 18.6k $222.7k | Unchanged |
| AXQ CAPITAL, LP 0.02% of their portfolio | 18.4k $221.0k | New |
| Landing Point Financial Group, LLC 0.07% of their portfolio | 18.2k $218.2k | Reduced -1.0k |
| Quadrature Capital Ltd 0.00% of their portfolio | 16.3k $195.0k | New |