PUMA BIOTECHNOLOGY INC PBYI
COM · Common Stock · CUSIP 74587V107 · ISIN US74587V1070
Pharmaceutical company
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersLos Angeles, CA
- Websitepumabiotechnology.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Shares outstanding: 49.0m as of 2024-07-29, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $3.26. Options: 5 managers hold calls ($416.9k notional), 4 hold puts ($83.6k).
Trends to Q2 2024
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 83 |
| Q4 2022 | 89 |
| Q1 2023 | 79 |
| Q2 2023 | 69 |
| Q3 2023 | 70 |
| Q4 2023 | 83 |
| Q1 2024 | 94 |
| Q2 2024 | 100 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 42 | 39 |
| Q1 2023 | 40 | 40 |
| Q2 2023 | 16 | 42 |
| Q3 2023 | 26 | 28 |
| Q4 2023 | 47 | 21 |
| Q1 2024 | 56 | 35 |
| Q2 2024 | 57 | 46 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2023 | $1.0m | $200.7k | 0.20 |
| Q4 2023 | $843.3k | $217.9k | 0.26 |
| Q1 2024 | $4.6m | $211.0k | 0.05 |
| Q2 2024 | $416.9k | $83.6k | 0.20 |
Biggest buyers
| BlackRock Inc. | Added | +2.0m |
| GEODE CAPITAL MANAGEMENT, LLC | Added | +497.2k |
| AMERICAN CENTURY COMPANIES INC | Added | +366.7k |
| STATE STREET CORP | Added | +341.6k |
| Schonfeld Strategic Advisors LLC | Added | +287.5k |
| Affinity Asset Advisors, LLC | New | +250.0k |
| Frazier Life Sciences Management, L.P. | Added | +246.3k |
| TANG CAPITAL MANAGEMENT LLC | New | +200.0k |
| STRS OHIO | New | +159.3k |
| GREAT POINT PARTNERS LLC | Added | +142.9k |
Biggest sellers
| Camber Capital Management LP | Sold out | -1.6m |
| MORGAN STANLEY | Reduced | -1.5m |
| JANE STREET GROUP, LLC | Reduced | -413.5k |
| GOLDMAN SACHS GROUP INC | Reduced | -250.0k |
| WELLINGTON MANAGEMENT GROUP LLP | Sold out | -170.8k |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | Reduced | -138.3k |
| Laurion Capital Management LP | Sold out | -131.2k |
| HRT FINANCIAL LP | Sold out | -127.2k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | -126.4k |
| TWO SIGMA ADVISERS, LP | Reduced | -119.9k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $228.9k70.2k shares |
| GROUP ONE TRADING LLC | Added | $166.3k51.0k shares |
| SIMPLEX TRADING, LLC | Reduced | $11.0k3.4k shares |
| CITADEL ADVISORS LLC | Reduced | $10.8k3.3k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| CITADEL ADVISORS LLC | Unchanged | $60.3k18.5k shares |
| SIMPLEX TRADING, LLC | Added | $23.0k7.3k shares |
| GROUP ONE TRADING LLC | Reduced | $326100 shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
AUERBACH ALAN H
13D · may seek influence
filed 2026-10-06
Stated purposeThe information set forth or incorporated in Item 3 above is incorporated herein by reference. From time to time, Mr. Auerbach may acquire beneficial ownership of additional shares of Common Stock or other securities of the Issuer by purchase, as compensation from the Issuer, or otherwise, including, but not limited to, awards of restricted Common Shares, options to purchase Common Shares, and restricted stock units for Common Shares, or dispose of some or all of the shares of Common Stock beneficially owned by Mr. Auerbach in the open market or in privately negotiated transactions (which may be with the Issuer or with third parties) on such terms and at such times as Mr. Auerbach may deem advisable. Mr. Auerbach is the President, Chief Executive Officer and a director of the Issuer. In … Full filing |
16.0% |
| ACORN BIOVENTURES, L.P. 13G · passive investor +1.3 pts · filed 2025-02-14 | 8.0% |
| BlackRock, Inc. 13G · institution filed 2025-04-17 | 5.6% |
Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-27)
Insider purchases and sales in Q2 2024
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q3 2022 | 0 | — | 6 | $225.0k | — |
| Q4 2022 | 0 | — | 4 | $19.1k | — |
| Q1 2023 | 0 | — | 5 | $217.3k | — |
| Q2 2023 | 0 | — | 7 | $285.3k | $285.3k |
| Q3 2023 | 0 | — | 5 | $338.4k | $338.4k |
| Q4 2023 | 0 | — | 2 | $71.8k | $1.1k |
| Q1 2024 | 0 | — | 5 | $386.7k | $386.7k |
| Q2 2024 | 0 | — | 5 | $234.0k | $234.0k |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2024-06-13 | Senderowicz Adrian Director | Sold plan | $89.9k27.0k shares |
| 2024-06-13 | WILSON TROY EDWARD Director | Sold plan | $89.9k27.0k shares |
| 2024-06-13 | MOYES JAY M Director | Sold plan | $73.5k22.0k shares |
| 2024-06-13 | Dorval Allison Director | Sold plan | $37.1k11.0k shares |
| 2024-06-13 | Stuglik Brian M Director | Sold plan | $33.6k9.9k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2024
| Manager | Shares | Change |
|---|---|---|
| VANGUARD GROUP INC 0.00% of their portfolio | 3.6m $11.7m | Added +107.7k |
| BlackRock Inc. 0.00% of their portfolio | 3.6m $11.6m | Added +2.0m |
| MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio | 3.2m $10.3m | Reduced -4.9k |
| Frazier Life Sciences Management, L.P. 0.47% of their portfolio | 3.1m $10.0m | Added +246.3k |
| ACADIAN ASSET MANAGEMENT LLC 0.02% of their portfolio | 2.0m $6.4m | Reduced -5.3k |
| RENAISSANCE TECHNOLOGIES LLC 0.01% of their portfolio | 1.8m $5.7m | Added +23.6k |
| GREAT POINT PARTNERS LLC 0.93% of their portfolio | 1.5m $4.8m | Added +142.9k |
| Eversept Partners, LP 0.33% of their portfolio | 1.3m $4.3m | Reduced -98.0k |
| Athyrium Capital Management, LP 12.21% of their portfolio | 1.3m $4.1m | Unchanged |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 950.1k $3.1m | Added +497.2k |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 738.9k $2.4m | Added +366.7k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 606.0k $2.0m | Added +37.7k |
| STATE STREET CORP 0.00% of their portfolio | 514.0k $1.7m | Added +341.6k |
| GLOBEFLEX CAPITAL L P 0.15% of their portfolio | 452.6k $1.5m | Reduced -39.1k |
| Connor, Clark & Lunn Investment Management Ltd. 0.00% of their portfolio | 354.5k $1.2m | Reduced -31.3k |
| Schonfeld Strategic Advisors LLC 0.01% of their portfolio | 334.1k $1.1m | Added +287.5k |
| MORGAN STANLEY 0.00% of their portfolio | 323.7k $1.1m | Reduced -1.5m |
| Bank of New York Mellon Corp 0.00% of their portfolio | 309.0k $1.0m | Added +120.1k |
| WINTON GROUP Ltd 0.07% of their portfolio | 300.6k $980.0k | Added +112.3k |
| SEI INVESTMENTS CO 0.00% of their portfolio | 289.5k $943.9k | Reduced -140 |
| Qube Research & Technologies Ltd 0.00% of their portfolio | 273.2k $890.5k | Reduced -114.0k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 256.3k $835.4k | Reduced -126.4k |
| Affinity Asset Advisors, LLC 0.13% of their portfolio | 250.0k $815.0k | New |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 200.6k $653.9k | Reduced -250.0k |
| MARSHALL WACE, LLP 0.00% of their portfolio | 200.1k $652.3k | Reduced -38.4k |
| TANG CAPITAL MANAGEMENT LLC 0.07% of their portfolio | 200.0k $652.0k | New |
| GSA CAPITAL PARTNERS LLP 0.04% of their portfolio | 189.8k $619.0k | Added +2.2k |
| FEDERATED HERMES, INC. 0.00% of their portfolio | 160.2k $522.4k | Reduced -691 |
| STRS OHIO 0.00% of their portfolio | 159.3k $519.3k | New |
| Prospera Financial Services Inc 0.01% of their portfolio | 149.6k $487.6k | Added +1.8k |
| RICE HALL JAMES & ASSOCIATES, LLC 0.03% of their portfolio | 144.8k $472.0k | Added +4.7k |
| Assenagon Asset Management S.A. 0.00% of their portfolio | 140.2k $457.1k | Added +70.1k |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.01% of their portfolio | 139.4k $454.4k | Unchanged |
| TWO SIGMA ADVISERS, LP 0.00% of their portfolio | 135.4k $441.4k | Reduced -119.9k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 126.2k $411.5k | Added +106.8k |
| Invesco Ltd. 0.00% of their portfolio | 118.8k $387.4k | New |
| Man Group plc 0.00% of their portfolio | 117.7k $383.6k | Reduced -94.0k |
| LAZARD ASSET MANAGEMENT LLC 0.00% of their portfolio | 107.9k $351.0k | Added +58.4k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 105.1k $342.5k | Added +21.5k |
| PANAGORA ASSET MANAGEMENT INC 0.00% of their portfolio | 102.8k $335.2k | New |
| FMR LLC 0.00% of their portfolio | 93.1k $303.4k | Added +1.4k |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP 0.00% of their portfolio | 92.2k $300.0k | Reduced -138.3k |
| O'SHAUGHNESSY ASSET MANAGEMENT, LLC 0.00% of their portfolio | 84.2k $274.5k | Added +7.1k |
| Squarepoint Ops LLC 0.00% of their portfolio | 71.4k $232.7k | Added +10.8k |
| BANK OF MONTREAL /CAN/ 0.00% of their portfolio | 70.4k $232.2k | Reduced -37.5k |
| MACQUARIE GROUP LTD 0.00% of their portfolio | 61.3k $200.0k | Reduced -1.5k |
| Nuveen Asset Management, LLC 0.00% of their portfolio | 55.9k $182.3k | New |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 50.3k $163.9k | Added +48.2k |
| XTX Topco Ltd 0.01% of their portfolio | 48.6k $158.5k | Reduced -5.5k |
| Alpine Global Management, LLC 0.02% of their portfolio | 40.1k $130.8k | New |
| Metis Global Partners, LLC 0.00% of their portfolio | 39.5k $128.9k | Unchanged |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 36.0k $117.3k | Reduced -24.4k |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 34.3k $111.8k | Reduced -47.4k |
| RITHOLTZ WEALTH MANAGEMENT 0.00% of their portfolio | 33.8k $110.1k | Reduced -3.6k |
| Trexquant Investment LP 0.00% of their portfolio | 32.7k $106.5k | Added +469 |
| Brandywine Global Investment Management, LLC 0.00% of their portfolio | 32.2k $105.0k | New |
| BARCLAYS PLC 0.00% of their portfolio | 31.7k $103.2k | Added +14.3k |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 31.0k $101.1k | New |
| LSV ASSET MANAGEMENT 0.00% of their portfolio | 30.4k $99.0k | Unchanged |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 30.1k $98.2k | Added +14.9k |
| State of Wyoming 0.01% of their portfolio | 27.0k $87.9k | Added +20.3k |
| Corebridge Financial, Inc. 0.00% of their portfolio | 22.3k $72.8k | First filing |
| OXFORD ASSET MANAGEMENT LLP 0.07% of their portfolio | 21.0k $68.5k | Not comparable |
| LPL Financial LLC 0.00% of their portfolio | 20.7k $67.4k | Unchanged |
| UBS Group AG 0.00% of their portfolio | 20.3k $66.3k | Added +9.7k |
| CITIGROUP INC 0.00% of their portfolio | 19.9k $64.7k | Reduced -110.6k |
| Focus Partners Advisor Solutions, LLC 0.00% of their portfolio | 19.2k $62.7k | Unchanged |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 17.8k $57.9k | New |
| PRUDENTIAL FINANCIAL INC 0.00% of their portfolio | 17.6k $57.3k | Added +2.4k |
| VICTORY CAPITAL MANAGEMENT INC 0.00% of their portfolio | 16.6k $54.0k | New |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 16.4k $53.6k | Added +8.1k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 15.8k $51.4k | Reduced -413.5k |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 15.6k $50.9k | New |
| Marathon Trading Investment Management LLC 0.01% of their portfolio | 14.2k $46.4k | Reduced -56.1k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 13.4k $0 | New |
| ROYCE & ASSOCIATES LP 0.00% of their portfolio | 11.7k $38.3k | Unchanged |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 11.6k $37.9k | New |
| PDT Partners, LLC 0.00% of their portfolio | 11.1k $36.3k | New |
| Patriot Financial Group Insurance Agency, LLC 0.01% of their portfolio | 11.0k $35.9k | Reduced -500 |
| MetLife Investment Management, LLC 0.00% of their portfolio | 11.0k $35.8k | New |
| COMMONWEALTH EQUITY SERVICES, LLC 0.00% of their portfolio | 10.8k $35.0k | Unchanged |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 4.4k $15.0k | New |
| Ameritas Investment Partners, Inc. 0.00% of their portfolio | 4.1k $13.2k | New |
| Legal & General Group Plc 0.00% of their portfolio | 3.9k $12.6k | New |
| SIMPLEX TRADING, LLC 0.00% of their portfolio | 3.5k $11.0k | Added +2.6k |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 3.2k $10.5k | Added +3.0k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 3.0k $9.8k | New |
| AMALGAMATED BANK 0.00% of their portfolio | 1.4k $5.0k | New |
| GHP Investment Advisors, Inc. 0.00% of their portfolio | 1.2k $3.8k | Unchanged |
| GPS Wealth Strategies Group, LLC 0.00% of their portfolio | 1.0k $3.3k | Unchanged |
| OSAIC HOLDINGS, INC. 0.00% of their portfolio | 977 $3.2k | Added +327 |
| CIBC Private Wealth Group LLC 0.00% of their portfolio | 775 $2.3k | Unchanged |
| Aspire Private Capital, LLC 0.00% of their portfolio | 700 $2.3k | Unchanged |
| CWM, LLC 0.00% of their portfolio | 500 $2.0k | New |
| US BANCORP \DE\ 0.00% of their portfolio | 200 $652 | Unchanged |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 35 $114 | Reduced -1.7k |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 20 $65 | New |
| Concord Wealth Partners 0.00% of their portfolio | 6 $20 | New |
| ELEVATION WEALTH PARTNERS, LLC 0.00% of their portfolio | 3 $10 | Unchanged |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. 0.00% of their portfolio | 0 $0 | Unchanged |