PROTARA THERAPEUTICS INC TARA
COM STK · Common Stock · CUSIP 74365U107
American pharmaceutical company
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersNew York, NY
- Founded2001
- Websiteproteontherapeutics.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($13.0k this quarter). Holder counts are more reliable. Shares outstanding: 59.1m as of 2026-08-07, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $3.82. Options: 2 managers hold calls ($169.2k notional), 2 hold puts ($102.8k).
Trends to Q2 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 32 |
| Q4 2022 | 31 |
| Q1 2023 | 30 |
| Q2 2023 | 30 |
| Q3 2023 | 32 |
| Q4 2023 | 31 |
| Q1 2024 | 35 |
| Q2 2024 | 39 |
| Q3 2024 | 36 |
| Q4 2024 | 61 |
| Q1 2025 | 60 |
| Q2 2025 | 77 |
| Q3 2025 | 81 |
| Q4 2025 | 105 |
| Q1 2026 | 114 |
| Q2 2026 | 120 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2024 | 18 | 14 |
| Q4 2024 | 40 | 15 |
| Q1 2025 | 32 | 19 |
| Q2 2025 | 52 | 21 |
| Q3 2025 | 39 | 33 |
| Q4 2025 | 75 | 23 |
| Q1 2026 | 75 | 44 |
| Q2 2026 | 76 | 45 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2025 | $182.8k | $260.7k | 1.43 |
| Q4 2025 | $907.2k | $107.1k | 0.12 |
| Q1 2026 | $1.3m | $245.4k | 0.19 |
| Q2 2026 | $169.2k | $102.8k | 0.61 |
Biggest buyers
| ORBIMED ADVISORS LLC | New | +2.2m |
| Balyasny Asset Management L.P. | New | +1.0m |
| Qube Research & Technologies Ltd | Added | +868.5k |
| MARSHALL WACE, LLP | Added | +650.3k |
| Verdad Advisers, LP | New | +312.2k |
| MILLENNIUM MANAGEMENT LLC | Added | +270.0k |
| BlackRock, Inc. | Added | +268.5k |
| JACOBS LEVY EQUITY MANAGEMENT, INC | Added | +245.3k |
| VANGUARD CAPITAL MANAGEMENT LLC | Added | +181.1k |
| NORTHERN TRUST CORP | Added | +177.5k |
Biggest sellers
| AIGH Capital Management LLC | Sold out | -1.6m |
| Patient Square Capital LP | Sold out | -1.0m |
| UBS Group AG | Reduced | -945.6k |
| J. Goldman & Co LP | Reduced | -721.2k |
| Point72 Asset Management, L.P. | Reduced | -603.8k |
| Burkehill Global Management, LP | Sold out | -450.0k |
| Assenagon Asset Management S.A. | Reduced | -447.7k |
| Alyeska Investment Group, L.P. | Reduced | -310.3k |
| Integral Health Asset Management, LLC | Reduced | -250.0k |
| ExodusPoint Capital Management, LP | Sold out | -116.3k |
Biggest calls
| GROUP ONE TRADING LLC | Reduced | $128.0k33.5k shares |
| SIMPLEX TRADING, LLC | Reduced | $41.3k10.8k shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $87.5k22.9k shares |
| GROUP ONE TRADING LLC | Unchanged | $15.3k4.0k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| Janus Henderson Group Ltd. 13G · institution -1.2 pts · filed 2026-08-13 | 8.4% |
| BlackRock, Inc. 13G · institution +1.6 pts · filed 2026-04-27 | 6.3% |
| MILLENNIUM MANAGEMENT LLC 13G · passive investor +0.6 pts · filed 2026-07-07 | 5.7% |
Insider purchases and sales since 1 Apr 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2024 | 0 | — | 0 | — | — |
| Q1 2025 | 0 | — | 1 | $96.1k | $96.1k |
| Q2 2025 | 1 | $63.8k | 0 | — | — |
| Q3 2025 | 0 | — | 0 | — | — |
| Q4 2025 | 0 | — | 0 | — | — |
| Q1 2026 | 0 | — | 0 | — | — |
| Q2 2026 | 0 | — | 2 | $1.0m | — |
| Q3 2026 | 0 | — | 0 | — | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2026-06-29 | Shefferman Jesse CEO and President, director | Sold | $882.2k215.7k shares |
| 2026-04-08 | Zummo Jacqueline Chief R&D Officer | Sold | $6.1k1.1k shares |
| 2026-04-01 | Zummo Jacqueline Chief R&D Officer | Sold | $118.9k22.6k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2026
| Manager | Shares | Change |
|---|---|---|
| Jupiter Topco LLC 0.01% of their portfolio | 4.7m $17.9m | First filing |
| BlackRock, Inc. 0.00% of their portfolio | 3.7m $14.0m | Added +268.5k |
| MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio | 3.1m $11.8m | Added +270.0k |
| Velan Capital Investment Management LP 6.66% of their portfolio | 2.8m $10.9m | Added +10.0k |
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 2.3m $8.8m | Added +181.1k |
| Blackstone Inc. 0.03% of their portfolio | 2.3m $8.7m | Unchanged |
| ORBIMED ADVISORS LLC 0.16% of their portfolio | 2.2m $8.5m | New |
| Sio Capital Management, LLC 1.26% of their portfolio | 1.9m $7.3m | Reduced -48.0k |
| ACORN CAPITAL ADVISORS, LLC 1.83% of their portfolio | 1.8m $6.7m | Unchanged |
| Integral Health Asset Management, LLC 0.24% of their portfolio | 1.5m $5.7m | Reduced -250.0k |
| 5AM Venture Management, LLC 1.82% of their portfolio | 1.4m $5.2m | Unchanged |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 1.3m $5.1m | Added +149.0k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 1.2m $4.7m | Added +163.8k |
| STATE STREET CORP 0.00% of their portfolio | 1.1m $4.1m | Added +63.2k |
| Qube Research & Technologies Ltd 0.00% of their portfolio | 1.0m $4.0m | Added +868.5k |
| Balyasny Asset Management L.P. 0.01% of their portfolio | 1.0m $3.9m | New |
| BAKER BROS. ADVISORS LP 0.02% of their portfolio | 971.6k $3.7m | Unchanged |
| ADAR1 Capital Management, LLC 0.17% of their portfolio | 940.5k $3.6m | Unchanged |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 882.2k $3.4m | Reduced -43.7k |
| MARSHALL WACE, LLP 0.00% of their portfolio | 701.0k $2.7m | Added +650.3k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 683.2k $2.6m | Added +152.0k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 552.3k $2.1m | Added +177.5k |
| Point72 Asset Management, L.P. 0.00% of their portfolio | 548.9k $2.1m | Reduced -603.8k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 546.2k $2.1m | Added +148.2k |
| Catalio Capital Management, LP 0.37% of their portfolio | 520.1k $2.0m | Reduced -59.9k |
| MORGAN STANLEY 0.00% of their portfolio | 508.4k $1.9m | Reduced -48.5k |
| Walleye Capital LLC 0.01% of their portfolio | 505.4k $1.9m | Added +62.0k |
| VANGUARD PORTFOLIO MANAGEMENT LLC 0.00% of their portfolio | 491.7k $1.9m | Added +79.1k |
| UBS Group AG 0.00% of their portfolio | 456.8k $1.7m | Reduced -945.6k |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 334.7k $1.3m | Added +25.8k |
| Verdad Advisers, LP 1.14% of their portfolio | 312.2k $1.2m | New |
| JACOBS LEVY EQUITY MANAGEMENT, INC 0.00% of their portfolio | 295.6k $1.1m | Added +245.3k |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 251.5k $960.7k | Added +125.8k |
| OPPENHEIMER & CO INC 0.01% of their portfolio | 238.4k $910.5k | Added +56.8k |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 209.0k $798.3k | Added +142.2k |
| Jump Financial, LLC 0.01% of their portfolio | 203.1k $775.8k | Added +136.3k |
| CIBC WORLD MARKET INC. 0.00% of their portfolio | 166.5k $636.0k | Reduced -9.0k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 158.0k $603.4k | Added +10.1k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 137.7k $526.0k | Added +8.0k |
| J. Goldman & Co LP 0.02% of their portfolio | 135.0k $515.7k | Reduced -721.2k |
| SUPERSTRING CAPITAL MANAGEMENT LP 0.29% of their portfolio | 121.5k $464.0k | Unchanged |
| Assenagon Asset Management S.A. 0.00% of their portfolio | 119.9k $458.0k | Reduced -447.7k |
| Fisher Asset Management, LLC 0.00% of their portfolio | 99.6k $380.3k | New |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 98.5k $376.2k | Added +5.5k |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.01% of their portfolio | 85.3k $326.0k | Added +15.0k |
| Nuveen, LLC 0.00% of their portfolio | 72.6k $277.4k | Added +8.8k |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 69.7k $266.1k | Added +31.8k |
| FMR LLC 0.00% of their portfolio | 68.2k $260.5k | Added +11.1k |
| XTX Topco Ltd 0.00% of their portfolio | 63.9k $244.3k | Added +5.1k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 63.2k $241.6k | Added +31.2k |
| TRUIST FINANCIAL CORP 0.00% of their portfolio | 60.0k $229.2k | Unchanged |
| Trexquant Investment LP 0.00% of their portfolio | 59.6k $227.7k | Added +41.7k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 57.7k $220.5k | Added +3.7k |
| ALPS ADVISORS INC 0.00% of their portfolio | 57.0k $217.9k | Added +13.0k |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 56.3k $214.9k | New |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 54.6k $208.6k | Added +23.9k |
| PRUDENTIAL FINANCIAL INC 0.00% of their portfolio | 50.7k $193.8k | Reduced -68.8k |
| NANO CAP NEW MILLENNIUM GROWTH FUND L P 0.15% of their portfolio | 50.0k $191.0k | Added +13.5k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 40.4k $154.3k | Reduced -76.2k |
| Alyeska Investment Group, L.P. 0.00% of their portfolio | 39.7k $151.8k | Reduced -310.3k |
| Quadrature Capital Ltd 0.00% of their portfolio | 39.3k $150.2k | New |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 38.5k $148.0k | Added +2.2k |
| Marex Group Ltd 0.00% of their portfolio | 35.2k $134.7k | Reduced -20.0k |
| WINTON GROUP Ltd 0.00% of their portfolio | 32.8k $125.3k | Added +4.7k |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO 0.00% of their portfolio | 29.7k $113.5k | New |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 28.5k $108.8k | Added +25.8k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 28.4k $108.4k | Reduced -398 |
| Invesco Ltd. 0.00% of their portfolio | 26.9k $102.6k | Added +8.9k |
| CITIGROUP INC 0.00% of their portfolio | 24.1k $92.2k | Added +9.7k |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 24.1k $92.0k | Reduced -6 |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 22.6k $94.0k | Added +1.1k |
| Jain Global LLC 0.00% of their portfolio | 21.0k $80.2k | New |
| Vanguard Global Advisers, LLC 0.00% of their portfolio | 20.1k $76.9k | Reduced -32.5k |
| PRELUDE CAPITAL MANAGEMENT, LLC 0.01% of their portfolio | 19.6k $74.9k | New |
| EntryPoint Capital, LLC 0.02% of their portfolio | 19.3k $73.7k | New |
| LPL Financial LLC 0.00% of their portfolio | 19.1k $73.1k | Reduced -17.0k |
| BARCLAYS PLC 0.00% of their portfolio | 18.6k $71.1k | Reduced -29.7k |
| Squarepoint Ops LLC 0.00% of their portfolio | 18.1k $69.2k | New |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 18.0k $94.0k | New |
| IEQ CAPITAL, LLC 0.00% of their portfolio | 17.9k $68.5k | New |
| Police & Firemen's Retirement System of New Jersey 0.00% of their portfolio | 17.6k $67.1k | Unchanged |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 14.9k $56.8k | Added +1.3k |
| INTECH INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 13.6k $51.8k | Reduced -227 |
| Mariner, LLC 0.00% of their portfolio | 11.9k $45.4k | New |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 11.5k $43.8k | New |
| D. E. Shaw & Co., Inc. 0.00% of their portfolio | 11.1k $42.5k | New |
| COMMONWEALTH EQUITY SERVICES, LLC 0.00% of their portfolio | 11.0k $42.0k | Unchanged |
| Corient Private Wealth LP 0.00% of their portfolio | 10.7k $40.8k | New |
| Essential Partners LLC 0.02% of their portfolio | 9.8k $37.4k | Reduced -70 |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 7.9k $30.2k | Unchanged |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 7.8k $29.0k | Added +4.3k |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 7.5k $28.8k | Reduced -3.5k |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 5.0k $19.1k | Added +387 |
| Legal & General Group Plc 0.00% of their portfolio | 4.5k $17.1k | Unchanged |
| Ameritas Investment Partners, Inc. 0.00% of their portfolio | 3.3k $12.6k | Unchanged |
| Integrated Wealth Concepts LLC 0.00% of their portfolio | 1.8k $6.7k | New |
| Arax Advisory Partners 0.00% of their portfolio | 1.7k $6.4k | New |
| Sterling Capital Management LLC 0.00% of their portfolio | 1.1k $4.0k | Reduced -648 |
| State of Wyoming 0.00% of their portfolio | 960 $3.7k | New |
| GAMMA Investing LLC 0.00% of their portfolio | 732 $2.8k | Added +155 |