PACIFIC BIOSCIENCES CALIF IN PACB
COM · Common Stock · CUSIP 69404D108 · ISIN US69404D1081
Biotechnology company founded in 2004 that develops and manufactures systems for gene sequencing and some novel real time biological observation
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($18.2m this quarter). Holder counts are more reliable. Shares outstanding: 272.5m as of 2024-07-31, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $1.37. Options: 14 managers hold calls ($2.4m notional), 11 hold puts ($3.0m).
Trends to Q2 2024
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 226 |
| Q4 2022 | 237 |
| Q1 2023 | 260 |
| Q2 2023 | 272 |
| Q3 2023 | 275 |
| Q4 2023 | 274 |
| Q1 2024 | 268 |
| Q2 2024 | 230 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 101 | 106 |
| Q1 2023 | 137 | 89 |
| Q2 2023 | 142 | 95 |
| Q3 2023 | 134 | 125 |
| Q4 2023 | 138 | 120 |
| Q1 2024 | 140 | 120 |
| Q2 2024 | 115 | 132 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2023 | $100.9m | $24.8m | 0.25 |
| Q4 2023 | $54.0m | $22.0m | 0.41 |
| Q1 2024 | $8.0m | $6.7m | 0.83 |
| Q2 2024 | $2.4m | $3.0m | 1.26 |
Biggest buyers
| EDMOND DE ROTHSCHILD HOLDING S.A. | Added | +6.2m |
| MADRONE ADVISORS, LLC | Added | +5.8m |
| MILLENNIUM MANAGEMENT LLC | Added | +2.2m |
| GOLDMAN SACHS GROUP INC | Added | +1.8m |
| Jackson Square Partners, LLC | Added | +1.7m |
| Assenagon Asset Management S.A. | New | +1.3m |
| JANE STREET GROUP, LLC | Added | +1.2m |
| MARSHALL WACE, LLP | Added | +1.1m |
| D. E. Shaw & Co., Inc. | Added | +836.2k |
| Koss-Olinger Consulting, LLC | New | +800.0k |
Biggest sellers
| T. Rowe Price Investment Management, Inc. | Sold out | -8.4m |
| Deep Track Capital, LP | Sold out | -7.0m |
| MACQUARIE GROUP LTD | Sold out | -6.6m |
| Bellevue Group AG | Sold out | -4.6m |
| FARALLON CAPITAL MANAGEMENT, L.L.C. | Reduced | -3.6m |
| Capital International Investors | Sold out | -3.1m |
| MORGAN STANLEY | Reduced | -2.6m |
| Eagle Health Investments LP | Sold out | -2.2m |
| DIMENSIONAL FUND ADVISORS LP | Reduced | -2.1m |
| Qube Research & Technologies Ltd | Sold out | -1.8m |
Biggest calls
| SIMPLEX TRADING, LLC | Added | $579.0k423.2k shares |
| GROUP ONE TRADING LLC | Added | $319.2k233.0k shares |
| Walleye Capital LLC | Reduced | $296.3k216.3k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $266.7k194.7k shares |
| CAPITAL FUND MANAGEMENT S.A. | Reduced | $236.9k172.9k shares |
| CITADEL ADVISORS LLC | Added | $202.3k147.7k shares |
| GTS SECURITIES LLC | Added | $173.7k126.8k shares |
| JANE STREET GROUP, LLC | Added | $147.5k107.7k shares |
| WOLVERINE TRADING, LLC | Added | $75.2k54.9k shares |
| Caption Management, LLC | Reduced | $42.7k31.2k shares |
Biggest puts
| GROUP ONE TRADING LLC | Added | $1.2m875.7k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $605.0k441.6k shares |
| JANE STREET GROUP, LLC | Added | $411.4k300.3k shares |
| CITADEL ADVISORS LLC | Reduced | $317.0k231.4k shares |
| MILLENNIUM MANAGEMENT LLC | Added | $205.5k150.0k shares |
| SIMPLEX TRADING, LLC | Reduced | $70.0k51.7k shares |
| Walleye Capital LLC | Reduced | $55.1k40.2k shares |
| GTS SECURITIES LLC | Reduced | $54.3k39.6k shares |
| Walleye Trading LLC | New | $47.5k34.7k shares |
| WOLVERINE TRADING, LLC | Added | $37.8k27.6k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| ARK Investment Management LLC 13G · institution -2.8 pts · filed 2026-08-14 | 9.6% |
| BlackRock, Inc. 13G · institution filed 2025-04-17 | 7.7% |
Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-27), MADRONE CAPITAL PARTNERS, LLC (2.8%, 2025-11-14)
Insider purchases and sales in Q2 2024
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q3 2022 | 0 | — | 2 | $600.5k | — |
| Q4 2022 | 0 | — | 1 | $487.8k | — |
| Q1 2023 | 0 | — | 5 | $614.8k | — |
| Q2 2023 | 0 | — | 1 | $65.0k | — |
| Q3 2023 | 0 | — | 4 | $1.9m | $209.5k |
| Q4 2023 | 0 | — | 1 | $200.0k | $200.0k |
| Q1 2024 | 1 | $176.0k | 5 | $1.4m | — |
| Q2 2024 | 0 | — | 1 | $10.7k | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2024-05-20 | Farmer Michele Officer | Sold | $10.7k5.3k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2024
| Manager | Shares | Change |
|---|---|---|
| ARK Investment Management LLC 0.40% of their portfolio | 33.2m $45.5m | Reduced -77.7k |
| VANGUARD GROUP INC 0.00% of their portfolio | 26.0m $35.6m | Reduced -607.5k |
| BlackRock Inc. 0.00% of their portfolio | 23.6m $32.3m | Added +213.7k |
| MADRONE ADVISORS, LLC 5.63% of their portfolio | 23.4m $32.0m | Added +5.8m |
| EDMOND DE ROTHSCHILD HOLDING S.A. 0.39% of their portfolio | 16.7m $22.9m | Added +6.2m |
| Sumitomo Mitsui Trust Group, Inc. 0.01% of their portfolio | 12.6m $17.3m | Reduced -183.8k |
| Amova Asset Management Americas, Inc. 0.20% of their portfolio | 12.6m $17.2m | Reduced -183.8k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 9.9m $13.6m | Reduced -1.4m |
| Jackson Square Partners, LLC 0.74% of their portfolio | 8.9m $12.2m | Added +1.7m |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 6.1m $8.4m | Added +460.1k |
| STATE STREET CORP 0.00% of their portfolio | 5.9m $8.1m | Added +166.5k |
| MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio | 4.6m $6.3m | Added +2.2m |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 4.0m $5.5m | Added +1.8m |
| Capital World Investors 0.00% of their portfolio | 3.4m $4.6m | Unchanged |
| MORGAN STANLEY 0.00% of their portfolio | 3.1m $4.2m | Reduced -2.6m |
| VK Services, LLC 0.88% of their portfolio | 2.6m $3.6m | Unchanged |
| NORTHERN TRUST CORP 0.00% of their portfolio | 2.5m $3.4m | Reduced -38.6k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 2.0m $2.7m | Reduced -30.0k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 1.9m $2.7m | Reduced -16.1k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 1.9m $2.6m | Added +264.8k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 1.7m $2.3m | Added +1.2m |
| SOROS FUND MANAGEMENT LLC 0.05% of their portfolio | 1.7m $2.3m | Added +65.0k |
| D. E. Shaw & Co., Inc. 0.00% of their portfolio | 1.6m $2.3m | Added +836.2k |
| MARSHALL WACE, LLP 0.00% of their portfolio | 1.6m $2.2m | Added +1.1m |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 1.3m $1.8m | Reduced -2.1m |
| Assenagon Asset Management S.A. 0.00% of their portfolio | 1.3m $1.8m | New |
| NORGES BANK 0.00% of their portfolio | 1.2m $1.7m | Reduced -338.9k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 1.0m $1.4m | Reduced -685.7k |
| Casdin Capital, LLC 0.11% of their portfolio | 1.0m $1.4m | Unchanged |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 1.0m $1.4m | Reduced -163.6k |
| BOURNE LENT ASSET MANAGEMENT INC 0.50% of their portfolio | 951.4k $1.3m | Added +297.0k |
| HHLR ADVISORS, LTD. 0.03% of their portfolio | 918.9k $1.3m | Unchanged |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 904.2k $1.2m | Reduced -578.1k |
| GROUP ONE TRADING LLC 0.04% of their portfolio | 900.1k $1.2m | Added +706.2k |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 835.4k $1.1m | Added +646.7k |
| UBS Group AG 0.00% of their portfolio | 829.1k $1.1m | Added +151.9k |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 818.9k $1.1m | First filing |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 817.8k $1.1m | Added +288.1k |
| Senvest Management, LLC 0.04% of their portfolio | 804.0k $1.1m | Added +109.4k |
| Koss-Olinger Consulting, LLC 0.10% of their portfolio | 800.0k $1.1m | New |
| Vestmark Advisory Solutions, Inc. 0.04% of their portfolio | 710.9k $973.9k | Reduced -224.4k |
| SEI INVESTMENTS CO 0.00% of their portfolio | 643.4k $881.5k | Reduced -914.3k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 598.7k $820.3k | Added +302.0k |
| GSA CAPITAL PARTNERS LLP 0.06% of their portfolio | 595.9k $816.0k | New |
| Squarepoint Ops LLC 0.00% of their portfolio | 524.6k $718.7k | New |
| Swiss National Bank 0.00% of their portfolio | 475.2k $651.1k | Unchanged |
| ArrowMark Colorado Holdings LLC 0.01% of their portfolio | 468.4k $641.7k | Unchanged |
| FEDERATED HERMES, INC. 0.00% of their portfolio | 446.9k $612.2k | New |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 436.9k $598.5k | Added +51.7k |
| NORDEA INVESTMENT MANAGEMENT AB 0.00% of their portfolio | 432.3k $594.5k | Added +218.2k |
| ORACLE INVESTMENT MANAGEMENT INC 0.62% of their portfolio | 423.1k $579.7k | Reduced -932.9k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 342.5k $469.3k | Added +71.8k |
| ALGERT GLOBAL LLC 0.02% of their portfolio | 341.1k $467.3k | Added +161.1k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 329.8k $451.8k | Added +15.6k |
| TD Asset Management Inc 0.00% of their portfolio | 292.7k $401.0k | Reduced -240.8k |
| Nan Fung Group Holdings Ltd 0.40% of their portfolio | 274.5k $376.0k | Unchanged |
| Nuveen Asset Management, LLC 0.00% of their portfolio | 270.2k $370.2k | Reduced -409.7k |
| Invesco Ltd. 0.00% of their portfolio | 253.9k $347.8k | Added +11.1k |
| BARCLAYS PLC 0.00% of their portfolio | 245.0k $335.6k | Reduced -420.1k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 241.1k $330.3k | Reduced -717 |
| Daiwa Securities Group Inc. 0.00% of their portfolio | 235.3k $322.0k | Added +9.5k |
| Legal & General Group Plc 0.00% of their portfolio | 234.6k $321.4k | Reduced -975 |
| Brevan Howard Capital Management LP 0.02% of their portfolio | 222.4k $304.7k | Added +182.4k |
| LPL Financial LLC 0.00% of their portfolio | 201.4k $276.0k | Added +20.8k |
| GUGGENHEIM CAPITAL LLC 0.00% of their portfolio | 189.8k $260.1k | Reduced -37.7k |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 169.1k $231.7k | Reduced -4.4k |
| Walleye Capital LLC 0.00% of their portfolio | 154.6k $211.8k | Added +148.2k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 154.2k $211.2k | Added +32.9k |
| Moloney Securities Asset Management, LLC 0.03% of their portfolio | 152.7k $209.2k | Reduced -12.0k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 148.6k $203.6k | Added +6.7k |
| Corebridge Financial, Inc. 0.00% of their portfolio | 147.2k $201.6k | First filing |
| BENJAMIN F. EDWARDS & COMPANY, INC. 0.00% of their portfolio | 141.8k $194.0k | Added +139.4k |
| FARALLON CAPITAL MANAGEMENT, L.L.C. 0.00% of their portfolio | 135.0k $184.9k | Reduced -3.6m |
| TWO SIGMA ADVISERS, LP 0.00% of their portfolio | 122.2k $167.4k | Reduced -22.2k |
| Koa Wealth Management, LLC 0.14% of their portfolio | 120.0k $164.4k | Unchanged |
| Clear Harbor Asset Management, LLC 0.01% of their portfolio | 119.9k $164.3k | Added +5.0k |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 119.5k $163.7k | Added +10.9k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 117.7k $161.3k | Reduced -50.3k |
| CITIGROUP INC 0.00% of their portfolio | 117.4k $160.8k | Added +66.4k |
| ENVESTNET ASSET MANAGEMENT INC 0.00% of their portfolio | 116.4k $159.4k | Reduced -9.1k |
| JANUS HENDERSON GROUP PLC 0.00% of their portfolio | 109.9k $150.1k | Reduced -1.4k |
| RAYMOND JAMES & ASSOCIATES 0.00% of their portfolio | 109.8k $150.4k | Added +23.2k |
| Vident Advisory, LLC 0.00% of their portfolio | 108.7k $148.9k | Added +92.5k |
| Engineers Gate Manager LP 0.00% of their portfolio | 102.3k $140.1k | Reduced -195.6k |
| Tidal Investments LLC 0.00% of their portfolio | 100.4k $137.6k | New |
| GABELLI FUNDS LLC 0.00% of their portfolio | 100.0k $137.0k | Unchanged |
| NJ State Employees Deferred Compensation Plan 0.02% of their portfolio | 100.0k $137.0k | Unchanged |
| Abacus Planning Group, Inc. 0.03% of their portfolio | 100.0k $137.0k | Unchanged |
| Lombard Odier Asset Management (USA) Corp 0.05% of their portfolio | 94.6k $129.5k | Added +20.1k |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 91.0k $124.7k | Added +8.5k |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 86.6k $118.7k | Added +2.1k |
| OSAIC HOLDINGS, INC. 0.00% of their portfolio | 86.2k $118.1k | Reduced -9.5k |
| Arete Wealth Advisors, LLC 0.01% of their portfolio | 82.9k $110.0k | Added +26.1k |
| HSBC HOLDINGS PLC 0.00% of their portfolio | 79.1k $105.6k | Added +32.9k |
| CARRET ASSET MANAGEMENT, LLC 0.01% of their portfolio | 77.6k $106.3k | Added +45.6k |
| Exome Asset Management LLC 0.09% of their portfolio | 75.3k $103.2k | Unchanged |
| DekaBank Deutsche Girozentrale 0.00% of their portfolio | 73.3k $96.0k | Unchanged |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 0.00% of their portfolio | 71.9k $98.6k | Added +840 |
| Cresset Asset Management, LLC 0.00% of their portfolio | 69.1k $94.6k | Reduced -9.9k |
| ARIZONA STATE RETIREMENT SYSTEM 0.00% of their portfolio | 68.6k $94.0k | Added +2.5k |