PACIFIC BIOSCIENCES CALIF IN PACB
COM · Common Stock · CUSIP 69404D108 · ISIN US69404D1081
Biotechnology company founded in 2004 that develops and manufactures systems for gene sequencing and some novel real time biological observation
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($10.1m this quarter). Holder counts are more reliable. Shares outstanding: 310.8m as of 2026-07-31, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $1.68. Options: 7 managers hold calls ($3.1m notional), 6 hold puts ($1.0m).
Trends to Q2 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 226 |
| Q4 2022 | 237 |
| Q1 2023 | 260 |
| Q2 2023 | 272 |
| Q3 2023 | 275 |
| Q4 2023 | 274 |
| Q1 2024 | 268 |
| Q2 2024 | 230 |
| Q3 2024 | 226 |
| Q4 2024 | 228 |
| Q1 2025 | 226 |
| Q2 2025 | 208 |
| Q3 2025 | 208 |
| Q4 2025 | 216 |
| Q1 2026 | 231 |
| Q2 2026 | 223 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2024 | 90 | 101 |
| Q4 2024 | 105 | 100 |
| Q1 2025 | 92 | 108 |
| Q2 2025 | 81 | 118 |
| Q3 2025 | 84 | 85 |
| Q4 2025 | 108 | 82 |
| Q1 2026 | 106 | 102 |
| Q2 2026 | 93 | 106 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2025 | $3.6m | $1.0m | 0.28 |
| Q4 2025 | $10.0m | $1.7m | 0.17 |
| Q1 2026 | $1.2m | $1.1m | 0.92 |
| Q2 2026 | $3.1m | $1.0m | 0.34 |
Biggest buyers
| BlackRock, Inc. | Added | +7.1m |
| Point72 Asset Management, L.P. | Added | +4.5m |
| GOLDMAN SACHS GROUP INC | Added | +2.2m |
| Longaeva Partners L.P. | New | +2.1m |
| CITADEL ADVISORS LLC | Added | +1.3m |
| TWO SIGMA INVESTMENTS, LP | Added | +733.0k |
| GEODE CAPITAL MANAGEMENT, LLC | Added | +631.3k |
| Numerai GP LLC | New | +621.5k |
| VANGUARD CAPITAL MANAGEMENT LLC | Added | +620.5k |
| Man Group plc | New | +597.3k |
Biggest sellers
| ARK Investment Management LLC | Reduced | -6.5m |
| Nuveen, LLC | Reduced | -1.9m |
| RENAISSANCE TECHNOLOGIES LLC | Reduced | -1.5m |
| MORGAN STANLEY | Reduced | -1.4m |
| JANE STREET GROUP, LLC | Reduced | -1.4m |
| HRT FINANCIAL LP | Sold out | -1.3m |
| Sumitomo Mitsui Trust Group, Inc. | Reduced | -1.0m |
| Amova Asset Management Americas, Inc. | Reduced | -1.0m |
| MILLENNIUM MANAGEMENT LLC | Reduced | -929.9k |
| Qube Research & Technologies Ltd | Reduced | -887.0k |
Biggest calls
| SIMPLEX TRADING, LLC | Added | $1.2m719.6k shares |
| GROUP ONE TRADING LLC | Added | $727.8k433.2k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $406.1k241.7k shares |
| JANE STREET GROUP, LLC | Reduced | $255.2k151.9k shares |
| IMC-Chicago, LLC | Reduced | $227.6k135.5k shares |
| CITADEL ADVISORS LLC | Reduced | $186.1k110.8k shares |
| HUB Investment Partners, LLC | Unchanged | $67.2k40.0k shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $673.0k400.6k shares |
| SIMPLEX TRADING, LLC | Reduced | $147.8k88.0k shares |
| CITADEL ADVISORS LLC | Added | $109.5k65.2k shares |
| GROUP ONE TRADING LLC | Reduced | $53.8k32.0k shares |
| IMC-Chicago, LLC | Reduced | $27.2k16.2k shares |
| JANE STREET GROUP, LLC | Reduced | $24.7k14.7k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| ARK Investment Management LLC 13G · institution -2.8 pts · filed 2026-08-14 | 9.6% |
| BlackRock, Inc. 13G · institution filed 2025-04-17 | 7.7% |
Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-27), MADRONE CAPITAL PARTNERS, LLC (2.8%, 2025-11-14)
Insider purchases and sales since 1 Apr 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2024 | 0 | — | 0 | — | — |
| Q1 2025 | 0 | — | 3 | $824.7k | — |
| Q2 2025 | 0 | — | 1 | $5.2k | — |
| Q3 2025 | 0 | — | 1 | $35.2k | — |
| Q4 2025 | 0 | — | 0 | — | — |
| Q1 2026 | 0 | — | 3 | $1.2m | — |
| Q2 2026 | 0 | — | 1 | $120.8k | — |
| Q3 2026 | 0 | — | 1 | $30.4k | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2026-08-17 | Van Oene Mark Officer | Sold | $30.4k26.9k shares |
| 2026-04-01 | Gibson James R II Officer | Sold | $120.8k88.2k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2026
| Manager | Shares | Change |
|---|---|---|
| BlackRock, Inc. 0.00% of their portfolio | 32.3m $54.3m | Added +7.1m |
| ARK Investment Management LLC 0.32% of their portfolio | 29.8m $50.0m | Reduced -6.5m |
| SOFTBANK GROUP CORP. 0.19% of their portfolio | 20.5m $34.4m | Unchanged |
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 13.4m $22.5m | Added +620.5k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 7.6m $12.8m | Added +631.3k |
| Sumitomo Mitsui Trust Group, Inc. 0.01% of their portfolio | 6.0m $10.1m | Reduced -1.0m |
| Amova Asset Management Americas, Inc. 0.13% of their portfolio | 6.0m $10.0m | Reduced -1.0m |
| STATE STREET CORP 0.00% of their portfolio | 6.0m $10.0m | Reduced -160.5k |
| Point72 Asset Management, L.P. 0.01% of their portfolio | 4.8m $8.0m | Added +4.5m |
| TWO SIGMA INVESTMENTS, LP 0.01% of their portfolio | 4.2m $7.1m | Added +733.0k |
| D. E. Shaw & Co., Inc. 0.00% of their portfolio | 4.2m $7.1m | Added +570.6k |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 4.0m $6.7m | Reduced -929.9k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 3.2m $5.4m | Added +2.2m |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 2.8m $4.8m | Added +1.3m |
| VANGUARD PORTFOLIO MANAGEMENT LLC 0.00% of their portfolio | 2.7m $4.5m | Reduced -196.5k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 2.7m $4.5m | Added +246.8k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 2.4m $4.0m | Added +222.0k |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 2.2m $3.7m | Added +201.1k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 2.1m $3.6m | Added +410.1k |
| Longaeva Partners L.P. 0.10% of their portfolio | 2.1m $3.6m | New |
| IQ EQ FUND MANAGEMENT (IRELAND) Ltd 0.18% of their portfolio | 1.7m $2.8m | Reduced -93.8k |
| Birchview Capital, LP 1.06% of their portfolio | 1.4m $2.3m | Reduced -150.0k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 1.3m $2.3m | Reduced -318.6k |
| Invesco Ltd. 0.00% of their portfolio | 1.3m $2.2m | Reduced -171.1k |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 1.3m $2.2m | Added +537.2k |
| Nuveen, LLC 0.00% of their portfolio | 1.0m $1.7m | Reduced -1.9m |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 966.2k $1.6m | Reduced -1.5m |
| BOURNE LENT ASSET MANAGEMENT INC 0.55% of their portfolio | 943.1k $1.6m | Reduced -8.0k |
| HHLR ADVISORS, LTD. 0.19% of their portfolio | 918.9k $1.5m | Unchanged |
| UBS Group AG 0.00% of their portfolio | 893.1k $1.5m | Reduced -747.0k |
| Universal- Beteiligungs- und Servicegesellschaft mbH 0.00% of their portfolio | 808.7k $1.4m | Unchanged |
| ACADIAN ASSET MANAGEMENT LLC 0.00% of their portfolio | 793.3k $1.3m | Added +374.5k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 767.6k $1.3m | Reduced -45.8k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 759.8k $1.3m | Reduced -139.8k |
| Casdin Capital, LLC 0.06% of their portfolio | 723.8k $1.2m | Unchanged |
| TUDOR INVESTMENT CORP ET AL 0.00% of their portfolio | 684.7k $1.2m | Unchanged |
| XTX Topco Ltd 0.01% of their portfolio | 638.9k $1.1m | Added +394.1k |
| Numerai GP LLC 0.09% of their portfolio | 621.5k $1.0m | New |
| CARRET ASSET MANAGEMENT, LLC 0.09% of their portfolio | 600.1k $1.0m | Added +41.0k |
| Man Group plc 0.00% of their portfolio | 597.3k $1.0m | New |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 596.8k $1.0m | Added +127.0k |
| Balyasny Asset Management L.P. 0.00% of their portfolio | 564.3k $948.1k | Added +303.8k |
| PEAK6 LLC 0.02% of their portfolio | 555.6k $933.3k | Reduced -43.5k |
| Vestmark Advisory Solutions, Inc. 0.01% of their portfolio | 478.2k $803.4k | Reduced -71.9k |
| MORGAN STANLEY 0.00% of their portfolio | 477.8k $802.7k | Reduced -1.4m |
| ArrowMark Colorado Holdings LLC 0.03% of their portfolio | 468.4k $786.9k | Unchanged |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 441.6k $742.0k | Added +105.4k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 387.1k $510.9k | Unchanged |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 357.0k $599.7k | Added +8.1k |
| Connor, Clark & Lunn Investment Management Ltd. 0.00% of their portfolio | 348.3k $585.2k | New |
| Mirador Capital Partners LP 0.07% of their portfolio | 342.5k $575.4k | Reduced -262.4k |
| LPL Financial LLC 0.00% of their portfolio | 337.5k $567.0k | Added +37.9k |
| Creative Planning 0.00% of their portfolio | 323.0k $542.6k | Reduced -4.4k |
| Qube Research & Technologies Ltd 0.00% of their portfolio | 298.0k $500.6k | Reduced -887.0k |
| GROUP ONE TRADING LLC 0.01% of their portfolio | 290.9k $488.6k | Reduced -74.2k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 283.1k $475.6k | Added +151.9k |
| HSBC HOLDINGS PLC 0.00% of their portfolio | 280.3k $462.6k | Added +31.8k |
| BARCLAYS PLC 0.00% of their portfolio | 277.0k $465.3k | Added +54.6k |
| WATER ISLAND CAPITAL LLC 0.05% of their portfolio | 273.7k $459.8k | Added +1.6k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 267.4k $449.2k | Added +22.6k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 231.8k $390.0k | Added +43.7k |
| Quadrature Capital Ltd 0.00% of their portfolio | 185.7k $311.9k | Added +73.2k |
| Green Alpha Advisors, LLC 0.20% of their portfolio | 178.7k $300.1k | Reduced -4.0k |
| OSAIC HOLDINGS, INC. 0.00% of their portfolio | 164.5k $276.4k | Added +124.2k |
| MARSHALL WACE, LLP 0.00% of their portfolio | 163.6k $274.9k | Added +82.3k |
| RAYMOND JAMES FINANCIAL INC 0.00% of their portfolio | 159.7k $268.4k | Reduced -4.8k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 157.2k $264.1k | Added +30.1k |
| AdvisorNet Financial, Inc 0.01% of their portfolio | 152.1k $255.6k | Added +10.1k |
| Main Street Research LLC 0.01% of their portfolio | 152.1k $255.5k | Unchanged |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 145.9k $252.5k | Added +7.4k |
| CITIGROUP INC 0.00% of their portfolio | 139.4k $234.2k | Added +106.3k |
| Voleon Capital Management LP 0.00% of their portfolio | 134.8k $226.5k | New |
| ENVESTNET ASSET MANAGEMENT INC 0.00% of their portfolio | 132.9k $223.3k | Reduced -16.0k |
| IEQ CAPITAL, LLC 0.00% of their portfolio | 123.8k $208.0k | Added +11.1k |
| Vanguard Global Advisers, LLC 0.00% of their portfolio | 121.8k $204.6k | Unchanged |
| Koa Wealth Management, LLC 0.14% of their portfolio | 120.0k $201.6k | Unchanged |
| BENJAMIN EDWARDS INC 0.00% of their portfolio | 107.7k $180.9k | Reduced -7.8k |
| KAVAR CAPITAL PARTNERS GROUP, LLC 0.02% of their portfolio | 103.3k $173.6k | Added +10.0k |
| Bridgewater Associates, LP 0.00% of their portfolio | 102.8k $172.6k | New |
| GABELLI FUNDS LLC 0.00% of their portfolio | 100.0k $168.0k | Unchanged |
| Cerity Partners LLC 0.00% of their portfolio | 98.5k $165.5k | Added +77.1k |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 84.8k $142.5k | Unchanged |
| Police & Firemen's Retirement System of New Jersey 0.00% of their portfolio | 80.0k $134.3k | Unchanged |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 75.3k $126.6k | Added +497 |
| HUB Investment Partners, LLC 0.00% of their portfolio | 75.0k $126.0k | Added +8.0k |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 0.00% of their portfolio | 71.9k $120.9k | Unchanged |
| HARTLINE INVESTMENT CORP/ 0.01% of their portfolio | 69.0k $115.9k | Unchanged |
| STIFEL FINANCIAL CORP 0.00% of their portfolio | 68.2k $114.7k | Reduced -1.8k |
| INTECH INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 67.4k $113.2k | Reduced -34.0k |
| SIMPLEX TRADING, LLC 0.00% of their portfolio | 65.7k $110.3k | Reduced -43.4k |
| SEI INVESTMENTS CO 0.00% of their portfolio | 59.2k $99.5k | Reduced -107.6k |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 57.1k $96.0k | Added +7.0k |
| CAPTRUST FINANCIAL ADVISORS 0.00% of their portfolio | 56.5k $94.9k | Added +12.1k |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC 0.00% of their portfolio | 55.0k $85.8k | Added +11.3k |
| Cetera Investment Advisers 0.00% of their portfolio | 54.7k $91.8k | Added +3.3k |
| State of Wyoming 0.01% of their portfolio | 54.3k $91.2k | Reduced -1.3k |
| MERCER GLOBAL ADVISORS INC /ADV 0.00% of their portfolio | 51.8k $87.0k | Added +17.1k |
| Abacus Planning Group, Inc. 0.01% of their portfolio | 51.2k $86.1k | Unchanged |
| Evolution Wealth Advisors, LLC 0.01% of their portfolio | 50.0k $84.0k | Unchanged |
| China Universal Asset Management Co., Ltd. 0.00% of their portfolio | 49.4k $83.0k | Reduced -4.2k |