ORIC PHARMACEUTICALS INC ORIC
COM · Common Stock · CUSIP 68622P109
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersSouth San Francisco, CA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($115.4k this quarter). Holder counts are more reliable. Shares outstanding: 103.7m as of 2026-07-27, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $10.83. Options: 6 managers hold calls ($12.4m notional), 3 hold puts ($1.2m).
Trends to Q2 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 77 |
| Q4 2022 | 65 |
| Q1 2023 | 72 |
| Q2 2023 | 84 |
| Q3 2023 | 92 |
| Q4 2023 | 93 |
| Q1 2024 | 113 |
| Q2 2024 | 114 |
| Q3 2024 | 123 |
| Q4 2024 | 130 |
| Q1 2025 | 144 |
| Q2 2025 | 143 |
| Q3 2025 | 152 |
| Q4 2025 | 165 |
| Q1 2026 | 182 |
| Q2 2026 | 181 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2024 | 58 | 52 |
| Q4 2024 | 67 | 46 |
| Q1 2025 | 81 | 53 |
| Q2 2025 | 77 | 86 |
| Q3 2025 | 91 | 54 |
| Q4 2025 | 97 | 55 |
| Q1 2026 | 89 | 85 |
| Q2 2026 | 110 | 72 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2025 | $447.2k | $2.2m | 4.88 |
| Q4 2025 | $382.8k | $0 | 0.00 |
| Q1 2026 | $1.0m | $959.1k | 0.92 |
| Q2 2026 | $12.4m | $1.2m | 0.10 |
Biggest buyers
| D. E. Shaw & Co., Inc. | Added | +1.5m |
| AIHC Capital Management Ltd | Added | +1.4m |
| PRICE T ROWE ASSOCIATES INC /MD/ | Added | +1.2m |
| STATE STREET CORP | Added | +1.2m |
| ALGERT GLOBAL LLC | Added | +1.1m |
| GOLDMAN SACHS GROUP INC | Added | +976.1k |
| BlackRock, Inc. | Added | +839.4k |
| Jones Hill Capital LP | New | +747.3k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | Added | +707.6k |
| MILLENNIUM MANAGEMENT LLC | Added | +663.7k |
Biggest sellers
| Pfizer Inc | Reduced | -4.4m |
| Paradigm Biocapital Advisors LP | Sold out | -1.7m |
| Logos Global Management LP | Sold out | -950.0k |
| ALKEON CAPITAL MANAGEMENT LLC | Reduced | -765.0k |
| VIKING GLOBAL INVESTORS LP | Reduced | -697.8k |
| Sofinnova Investments, Inc. | Sold out | -679.6k |
| ORBIMED ADVISORS LLC | Reduced | -678.9k |
| LORD, ABBETT & CO. LLC | Sold out | -542.6k |
| Polar Capital Holdings Plc | Sold out | -539.4k |
| Balyasny Asset Management L.P. | Reduced | -499.6k |
Biggest calls
| SILVERARC CAPITAL MANAGEMENT, LLC | New | $7.4m682.6k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $1.9m178.7k shares |
| Caption Management, LLC | New | $1.2m110.0k shares |
| SPHERA FUNDS MANAGEMENT LTD. | New | $1.1m100.0k shares |
| SIMPLEX TRADING, LLC | Added | $515.5k47.6k shares |
| CITADEL ADVISORS LLC | Added | $281.6k26.0k shares |
Biggest puts
| Caption Management, LLC | New | $1.1m100.0k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | New | $154.9k14.3k shares |
| SIMPLEX TRADING, LLC | Unchanged | $4.3k400 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| Nextech Crossover I GP S.a r.l. 13G · passive investor filed 2025-08-14 | 8.4% |
| VIKING GLOBAL INVESTORS LP 13G · passive investor -2.2 pts · filed 2026-05-15 | 7.8% |
| EcoR1 Capital, LLC 13G · institution new · filed 2025-08-05 | 6.9% |
| BlackRock, Inc. 13G · institution +1.4 pts · filed 2026-01-21 | 5.6% |
| PRICE T ROWE ASSOCIATES INC /MD/ 13G · institution new · filed 2026-05-15 | 5.4% |
Fell to 5% or below in the last year: Point72 Asset Management, L.P. (0.0%, 2026-05-15), Venrock Healthcare Capital Partners III, L.P. (4.2%, 2026-05-15), PFIZER INC (3.3%, 2026-05-12), COLUMN GROUP II, LP (3.7%, 2025-11-17), ALKEON CAPITAL MANAGEMENT LLC (4.6%, 2025-11-13)
Insider purchases and sales since 1 Apr 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2024 | 0 | — | 3 | $350.7k | — |
| Q1 2025 | 0 | — | 0 | — | — |
| Q2 2025 | 1 | $263.0k | 1 | $416.3k | $416.3k |
| Q3 2025 | 0 | — | 2 | $2.0m | $2.0m |
| Q4 2025 | 0 | — | 3 | $1.7m | $1.3m |
| Q1 2026 | 0 | — | 2 | $782.9k | $782.9k |
| Q2 2026 | 0 | — | 0 | — | — |
| Q3 2026 | 0 | — | 2 | $1.4m | $1.4m |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2026-09-28 | Piscitelli Dominic Chief Financial Officer | Sold plan | $181.3k13.4k shares |
| 2026-09-24 | Piscitelli Dominic Chief Financial Officer | Sold plan | $8.1k600 shares |
| 2026-08-26 | Piscitelli Dominic Chief Financial Officer | Sold plan | $1.1m77.0k shares |
| 2026-07-24 | Heyman Richard A. Director | Sold plan | $84.1k7.0k shares |
| 2026-07-24 | Heyman Richard A. Director · See footnote | Sold plan | $73.3k6.1k shares |
| 2026-07-06 | Heyman Richard A. Director · See footnote | Sold plan | $3.6k300 shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2026
| Manager | Shares | Change |
|---|---|---|
| Nextech Invest Ltd. 3.68% of their portfolio | 7.2m $77.6m | Unchanged |
| BlackRock, Inc. 0.00% of their portfolio | 6.8m $73.9m | Added +839.4k |
| EcoR1 Capital, LLC 3.61% of their portfolio | 6.7m $72.9m | Unchanged |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.01% of their portfolio | 6.6m $71.7m | Added +1.2m |
| VIKING GLOBAL INVESTORS LP 0.16% of their portfolio | 5.1m $55.5m | Reduced -697.8k |
| STATE STREET CORP 0.00% of their portfolio | 4.9m $53.0m | Added +1.2m |
| SR One Capital Management, LP 4.81% of their portfolio | 4.6m $50.0m | Added +100.5k |
| Venrock Adviser, LLC 1.42% of their portfolio | 4.3m $46.8m | Unchanged |
| NEA Management Company, LLC 2.81% of their portfolio | 4.1m $44.6m | Unchanged |
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 4.0m $42.8m | Added +264.2k |
| AIHC Capital Management Ltd 39.77% of their portfolio | 3.8m $41.5m | Added +1.4m |
| ALKEON CAPITAL MANAGEMENT LLC 0.16% of their portfolio | 3.7m $40.5m | Reduced -765.0k |
| Column Group LLC 43.53% of their portfolio | 3.5m $38.3m | Unchanged |
| Siren, L.L.C. 0.66% of their portfolio | 3.0m $32.5m | Unchanged |
| FMR LLC 0.00% of their portfolio | 2.6m $28.5m | Added +201.4k |
| CITADEL ADVISORS LLC 0.02% of their portfolio | 2.6m $28.1m | Added +172.6k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 2.5m $26.6m | Added +976.1k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 2.1m $22.6m | Added +251.3k |
| First Turn Management, LLC 2.34% of their portfolio | 2.0m $21.8m | Unchanged |
| ORBIMED ADVISORS LLC 0.41% of their portfolio | 2.0m $21.8m | Reduced -678.9k |
| Integral Health Asset Management, LLC 0.84% of their portfolio | 1.9m $20.6m | Added +500.0k |
| MPM BIOIMPACT LLC 1.24% of their portfolio | 1.9m $20.4m | Added +78.2k |
| Vivo Capital, LLC 1.83% of their portfolio | 1.8m $20.0m | Unchanged |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 1.8m $19.5m | Added +330.1k |
| FRANKLIN RESOURCES INC 0.00% of their portfolio | 1.8m $19.5m | Added +344.5k |
| MORGAN STANLEY 0.00% of their portfolio | 1.8m $19.4m | Added +111.5k |
| D. E. Shaw & Co., Inc. 0.01% of their portfolio | 1.6m $17.1m | Added +1.5m |
| Woodline Partners LP 0.04% of their portfolio | 1.2m $13.5m | Unchanged |
| ALGERT GLOBAL LLC 0.16% of their portfolio | 1.2m $13.2m | Added +1.1m |
| BRAIDWELL LP 0.49% of their portfolio | 1.2m $13.2m | Added +86.5k |
| Candriam S.C.A. 0.06% of their portfolio | 1.2m $12.8m | Added +605.7k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 1.1m $11.7m | Added +34.9k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.02% of their portfolio | 1.1m $11.4m | Added +707.6k |
| Defilade Capital Management, L.P. 1.52% of their portfolio | 1.0m $11.3m | Added +204.8k |
| Euclidean Capital LLC 2.44% of their portfolio | 989.4k $10.7m | Unchanged |
| ROYCE & ASSOCIATES LP 0.09% of their portfolio | 979.7k $10.6m | Reduced -227.6k |
| EVENTIDE ASSET MANAGEMENT, LLC 0.14% of their portfolio | 954.8k $10.3m | Added +1.3k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 806.3k $8.7m | Added +95.4k |
| Qube Research & Technologies Ltd 0.01% of their portfolio | 794.5k $8.6m | Reduced -64.9k |
| SPHERA FUNDS MANAGEMENT LTD. 1.17% of their portfolio | 753.0k $8.2m | Added +215.4k |
| Jones Hill Capital LP 1.72% of their portfolio | 747.3k $8.1m | New |
| SILVERARC CAPITAL MANAGEMENT, LLC 0.89% of their portfolio | 738.9k $8.0m | Reduced -361.1k |
| NEXTBio Capital Management LP 3.52% of their portfolio | 706.1k $7.6m | Added +182.5k |
| MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio | 697.7k $7.6m | Added +663.7k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 677.8k $7.3m | Added +72.8k |
| VANGUARD PORTFOLIO MANAGEMENT LLC 0.00% of their portfolio | 628.7k $6.8m | Added +58.0k |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 603.7k $6.5m | New |
| ArrowMark Colorado Holdings LLC 0.26% of their portfolio | 582.9k $6.3m | Reduced -377.6k |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 566.0k $6.1m | Added +58.7k |
| Connor, Clark & Lunn Investment Management Ltd. 0.01% of their portfolio | 518.5k $5.6m | Reduced -3.6k |
| SUPERSTRING CAPITAL MANAGEMENT LP 2.78% of their portfolio | 406.1k $4.4m | Added +290.8k |
| Blue Owl Capital Holdings LP 0.66% of their portfolio | 400.0k $4.3m | Added +250.0k |
| VICTORY CAPITAL MANAGEMENT INC 0.00% of their portfolio | 393.1k $4.3m | Reduced -12.2k |
| Pfizer Inc 2.09% of their portfolio | 372.9k $3.6m | Reduced -4.4m |
| Redmile Group, LLC 0.26% of their portfolio | 362.0k $3.9m | Reduced -53.7k |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 358.8k $3.9m | Added +188.7k |
| Boxer Capital Management, LLC 0.29% of their portfolio | 350.0k $3.8m | Added +173.5k |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 345.0k $3.7m | Added +323.9k |
| Squarepoint Ops LLC 0.01% of their portfolio | 344.3k $3.7m | New |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 308.3k $3.1m | Reduced -15.3k |
| CITIGROUP INC 0.00% of their portfolio | 248.8k $2.7m | Added +231.8k |
| TD Asset Management Inc 0.00% of their portfolio | 246.0k $2.7m | Reduced -12.6k |
| UBS Group AG 0.00% of their portfolio | 222.9k $2.4m | Added +28.2k |
| Trexquant Investment LP 0.01% of their portfolio | 221.8k $2.4m | Added +197.8k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 220.1k $2.4m | Added +29.6k |
| XTX Topco Ltd 0.03% of their portfolio | 217.8k $2.4m | Added +174.5k |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 213.4k $2.3m | Added +27.3k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 174.2k $1.9m | Reduced -7.9k |
| Nuveen, LLC 0.00% of their portfolio | 172.2k $1.9m | Added +19.1k |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 168.6k $1.8m | Added +21.8k |
| HRT FINANCIAL LP 0.00% of their portfolio | 153.2k $1.7m | New |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 139.3k $1.5m | Added +116.2k |
| Jump Financial, LLC 0.01% of their portfolio | 131.4k $1.4m | New |
| Atom Investors LP 0.13% of their portfolio | 130.1k $1.4m | Reduced -96.7k |
| Ishara Investments LP 0.98% of their portfolio | 123.0k $1.3m | Added +20.5k |
| Invesco Ltd. 0.00% of their portfolio | 107.8k $1.2m | Reduced -1.2k |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 99.7k $1.1m | Reduced -163.3k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 93.9k $1.0m | Added +14.9k |
| Rafferty Asset Management, LLC 0.00% of their portfolio | 90.8k $983.0k | Reduced -24.7k |
| Abu Dhabi Investment Council Co P.J.S.C 0.14% of their portfolio | 89.4k $968.6k | Unchanged |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 87.0k $942.3k | Added +47.9k |
| Swiss National Bank 0.00% of their portfolio | 86.2k $933.5k | Unchanged |
| WINTON GROUP Ltd 0.03% of their portfolio | 83.0k $898.9k | New |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 73.9k $800.1k | Added +22.5k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 72.1k $780.4k | Added +23.7k |
| Engineers Gate Manager LP 0.01% of their portfolio | 64.1k $693.7k | New |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 63.8k $808.5k | Unchanged |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 63.5k $687.4k | Added +9.2k |
| Tidal Investments LLC 0.00% of their portfolio | 58.0k $627.9k | Added +375 |
| Tema ETFs LLC 0.02% of their portfolio | 58.0k $627.9k | First filing |
| SG Americas Securities, LLC 0.00% of their portfolio | 52.1k $564.0k | Added +36.0k |
| Caption Management, LLC 0.02% of their portfolio | 48.1k $521.2k | New |
| PROFUND ADVISORS LLC 0.01% of their portfolio | 45.7k $494.9k | Reduced -5.8k |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 45.0k $479.7k | Added +5.8k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 43.8k $474.8k | Added +8.2k |
| TUDOR INVESTMENT CORP ET AL 0.00% of their portfolio | 42.4k $459.3k | Added +8.7k |
| Virtus Investment Advisers, LLC 0.10% of their portfolio | 39.6k $428.5k | Added +10.5k |
| AXQ CAPITAL, LP 0.04% of their portfolio | 36.5k $395.5k | New |
| Quadrature Capital Ltd 0.00% of their portfolio | 36.3k $393.1k | New |
| LMR Partners LLP 0.00% of their portfolio | 35.3k $381.9k | Unchanged |