OPKO HEALTH INC OPK
COM · Common Stock · CUSIP 68375N103 · ISIN US68375N1037
Medical test and medication company
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Shares outstanding: 772.7m as of 2022-10-31, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $1.89. Options: 12 managers hold calls ($6.5m notional), 12 hold puts ($9.4m).
Biggest calls
| GROUP ONE TRADING LLC | — | $2.9m1.5m shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | — | $1.3m686.7k shares |
| SIMPLEX TRADING, LLC | — | $650.0k344.1k shares |
| JANE STREET GROUP, LLC | — | $581.0k307.6k shares |
| Caption Management, LLC | — | $567.0k300.0k shares |
| CITADEL ADVISORS LLC | — | $314.0k165.9k shares |
| WOLVERINE TRADING, LLC | — | $101.0k53.9k shares |
| Marathon Trading Investment Management LLC | — | $38.0k20.0k shares |
| HAP Trading, LLC | — | $4.0k44.4k shares |
| JPMORGAN CHASE & CO | — | $1.0k600 shares |
Biggest puts
| GROUP ONE TRADING LLC | — | $2.9m1.5m shares |
| WOLVERINE ASSET MANAGEMENT LLC | — | $2.3m1.2m shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | — | $2.1m1.1m shares |
| JANE STREET GROUP, LLC | — | $778.0k411.8k shares |
| Caption Management, LLC | — | $567.0k300.0k shares |
| CITADEL ADVISORS LLC | — | $363.0k192.2k shares |
| SIMPLEX TRADING, LLC | — | $276.0k146.1k shares |
| WOLVERINE TRADING, LLC | — | $37.0k19.7k shares |
| HAP Trading, LLC | — | $19.0k15.5k shares |
| Cutler Group LLC / CA | — | $15.0k14.4k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| FROST PHILLIP MD ET AL 13D · may seek influence +1.3 pts · filed 2026-07-01 | 34.1% |
| Rubric Capital Management LP 13G · institution filed 2025-07-09 | 6.0% |
Insider purchases and sales in Q3 2022
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2020 | 0 | — | 0 | — | — |
| Q1 2021 | 0 | — | 0 | — | — |
| Q2 2021 | 0 | — | 0 | — | — |
| Q3 2021 | 0 | — | 0 | — | — |
| Q4 2021 | 0 | — | 0 | — | — |
| Q1 2022 | 1 | $4.8m | 0 | — | — |
| Q2 2022 | 2 | $5.9m | 0 | — | — |
| Q3 2022 | 1 | $2.5m | 0 | — | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2022-09-26 | FROST PHILLIP MD ET AL +1 CEO & Chairman, director · See Footnote | Bought | $90.0k50.0k shares |
| 2022-09-23 | FROST PHILLIP MD ET AL +1 CEO & Chairman, director · See Footnote | Bought | $92.3k50.0k shares |
| 2022-09-22 | FROST PHILLIP MD ET AL +1 CEO & Chairman, director · See Footnote | Bought | $94.9k50.0k shares |
| 2022-09-21 | FROST PHILLIP MD ET AL +1 CEO & Chairman, director · See Footnote | Bought | $95.6k50.0k shares |
| 2022-09-20 | FROST PHILLIP MD ET AL +1 CEO & Chairman, director · See Footnote | Bought | $97.0k50.0k shares |
| 2022-09-19 | FROST PHILLIP MD ET AL +1 CEO & Chairman, director · See Footnote | Bought | $98.6k50.0k shares |
| 2022-09-15 | FROST PHILLIP MD ET AL +1 CEO & Chairman, director · See Footnote | Bought | $413.5k200.0k shares |
| 2022-09-02 | FROST PHILLIP MD ET AL +1 CEO & Chairman, director · See Footnote | Bought | $214.2k100.0k shares |
| 2022-08-17 | FROST PHILLIP MD ET AL +1 CEO & Chairman, director · See Footnote | Bought | $508.6k200.0k shares |
| 2022-08-05 | FROST PHILLIP MD ET AL +1 CEO & Chairman, director · See Footnote | Bought | $803.1k350.0k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q3 2022
| Manager | Shares | Change |
|---|---|---|
| VANGUARD GROUP INC 0.00% of their portfolio | 40.3m $76.1m | — |
| BlackRock Inc. 0.00% of their portfolio | 34.5m $65.2m | — |
| DIMENSIONAL FUND ADVISORS LP 0.01% of their portfolio | 10.8m $20.5m | — |
| STATE STREET CORP 0.00% of their portfolio | 10.4m $19.6m | — |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 7.8m $14.8m | — |
| D. E. Shaw & Co., Inc. 0.02% of their portfolio | 6.0m $11.3m | — |
| ORACLE INVESTMENT MANAGEMENT INC 5.53% of their portfolio | 5.1m $9.6m | — |
| NORTHERN TRUST CORP 0.00% of their portfolio | 3.9m $7.4m | — |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 3.8m $7.2m | — |
| Invesco Ltd. 0.00% of their portfolio | 3.4m $6.4m | — |
| NORGES BANK 0.00% of their portfolio | 3.2m $6.1m | — |
| TWO SIGMA INVESTMENTS, LP 0.02% of their portfolio | 2.9m $5.5m | — |
| RENAISSANCE TECHNOLOGIES LLC 0.01% of their portfolio | 2.8m $5.4m | — |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 2.8m $5.3m | — |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 2.4m $4.5m | — |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 2.3m $4.3m | — |
| Nuveen Asset Management, LLC 0.00% of their portfolio | 2.2m $4.2m | — |
| CITIGROUP INC 0.01% of their portfolio | 2.1m $4.0m | — |
| MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio | 2.1m $4.0m | — |
| TWO SIGMA ADVISERS, LP 0.01% of their portfolio | 2.1m $4.0m | — |
| Bank of New York Mellon Corp 0.00% of their portfolio | 2.0m $3.9m | — |
| Phoenix Financial Ltd. 0.07% of their portfolio | 1.6m $3.0m | — |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 1.6m $3.1m | — |
| MORGAN STANLEY 0.00% of their portfolio | 1.3m $2.5m | — |
| NORDEA INVESTMENT MANAGEMENT AB 0.00% of their portfolio | 1.3m $2.5m | — |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 1.2m $2.3m | — |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 1.1m $2.1m | — |
| PRUDENTIAL FINANCIAL INC 0.00% of their portfolio | 1.0m $2.0m | — |
| Swiss National Bank 0.00% of their portfolio | 1.0m $2.0m | — |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 850.2k $1.6m | — |
| GROUP ONE TRADING LLC 0.05% of their portfolio | 835.8k $1.6m | — |
| AWM Investment Company, Inc. 0.23% of their portfolio | 800.0k $1.5m | — |
| JUPITER ASSET MANAGEMENT LTD 0.02% of their portfolio | 765.2k $1.4m | — |
| Connor, Clark & Lunn Investment Management Ltd. 0.01% of their portfolio | 757.2k $1.4m | — |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 648.7k $1.2m | — |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 606.0k $1.1m | — |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 540.6k $1.0m | — |
| AXA S.A. 0.00% of their portfolio | 523.9k $990.0k | — |
| Schonfeld Strategic Advisors LLC 0.01% of their portfolio | 478.4k $904.0k | — |
| Cubist Systematic Strategies, LLC 0.01% of their portfolio | 477.6k $903.0k | — |
| Candriam S.C.A. 0.01% of their portfolio | 452.3k $855.0k | — |
| Graham Capital Management, L.P. 0.04% of their portfolio | 450.6k $851.0k | — |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 450.3k $851.0k | — |
| HRT FINANCIAL LP 0.01% of their portfolio | 445.1k $841.0k | — |
| ALPS ADVISORS INC 0.01% of their portfolio | 421.4k $796.0k | — |
| CREDIT SUISSE AG/ 0.00% of their portfolio | 409.3k $773.0k | — |
| COMMONWEALTH EQUITY SERVICES, LLC 0.00% of their portfolio | 407.6k $770.0k | — |
| Legal & General Group Plc 0.00% of their portfolio | 376.3k $712.0k | — |
| OCCUDO QUANTITATIVE STRATEGIES LP 0.05% of their portfolio | 349.6k $661.0k | — |
| TUDOR INVESTMENT CORP ET AL 0.02% of their portfolio | 341.1k $645.0k | — |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 334.1k $631.4k | — |
| VICTORY CAPITAL MANAGEMENT INC 0.00% of their portfolio | 333.2k $630.0k | — |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 331.2k $626.0k | — |
| Engineers Gate Manager LP 0.04% of their portfolio | 313.1k $592.0k | — |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 272.1k $515.0k | — |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 261.7k $495.0k | — |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 246.9k $466.0k | — |
| ETF MANAGERS GROUP, LLC 0.01% of their portfolio | 227.8k $431.0k | — |
| Hennion & Walsh Asset Management, Inc. 0.03% of their portfolio | 222.0k $419.0k | — |
| UBS Group AG 0.00% of their portfolio | 218.5k $413.0k | — |
| MetLife Investment Management, LLC 0.00% of their portfolio | 214.4k $405.2k | — |
| Cambridge Investment Research Advisors, Inc. 0.00% of their portfolio | 210.3k $397.0k | — |
| Teton Advisors, Inc. 0.10% of their portfolio | 210.0k $397.0k | — |
| X-Square Capital, LLC 0.25% of their portfolio | 205.4k $388.0k | — |
| PRINCIPAL FINANCIAL GROUP INC 0.00% of their portfolio | 203.6k $385.0k | — |
| GAMCO INVESTORS, INC. ET AL 0.00% of their portfolio | 200.0k $378.0k | — |
| GABELLI FUNDS LLC 0.00% of their portfolio | 200.0k $378.0k | — |
| AMERICAN INTERNATIONAL GROUP, INC. 0.00% of their portfolio | 191.7k $362.0k | — |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 190.7k $360.4k | — |
| FIRST TRUST ADVISORS LP 0.00% of their portfolio | 190.6k $360.0k | — |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 0.00% of their portfolio | 176.0k $333.0k | — |
| JANUS HENDERSON GROUP PLC 0.00% of their portfolio | 175.7k $332.0k | — |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 170.8k $322.7k | — |
| CAPITAL ADVISORS INC/OK 0.01% of their portfolio | 164.6k $285.0k | — |
| OSAIC HOLDINGS, INC. 0.00% of their portfolio | 151.3k $287.0k | — |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 149.6k $283.0k | — |
| New York Life Investment Management LLC 0.00% of their portfolio | 146.3k $277.0k | — |
| VAN ECK ASSOCIATES CORP 0.00% of their portfolio | 141.9k $268.0k | — |
| SG Americas Securities, LLC 0.00% of their portfolio | 137.5k $260.0k | — |
| WILBANKS SMITH & THOMAS ASSET MANAGEMENT LLC 0.01% of their portfolio | 136.0k $257.0k | — |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 131.3k $248.0k | — |
| ARIZONA STATE RETIREMENT SYSTEM 0.00% of their portfolio | 120.4k $227.0k | — |
| Csenge Advisory Group 0.02% of their portfolio | 117.0k $221.0k | — |
| HIGHLINE WEALTH PARTNERS LLC 0.16% of their portfolio | 106.7k $201.6k | — |
| Handelsbanken Fonder AB 0.00% of their portfolio | 101.6k $192.0k | — |
| Quantbot Technologies LP 0.01% of their portfolio | 101.1k $190.0k | — |
| INTREPID CAPITAL MANAGEMENT INC 0.15% of their portfolio | 100.0k $189.0k | — |
| Ergoteles LLC 0.01% of their portfolio | 97.5k $184.0k | — |
| Creative Planning 0.00% of their portfolio | 94.7k $179.0k | — |
| Dynamic Technology Lab Private Ltd 0.02% of their portfolio | 91.6k $173.0k | — |
| CANADA LIFE ASSURANCE Co 0.00% of their portfolio | 91.1k $171.0k | — |
| Weiss Multi-Strategy Advisers LLC 0.00% of their portfolio | 85.0k $161.0k | — |
| HOLLENCREST CAPITAL MANAGEMENT 0.02% of their portfolio | 84.0k $159.0k | — |
| Caption Management, LLC 0.03% of their portfolio | 80.0k $151.0k | — |
| SHELL ASSET MANAGEMENT CO 0.01% of their portfolio | 78.6k $149.0k | — |
| AE Wealth Management LLC 0.00% of their portfolio | 78.3k $148.0k | — |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 73.4k $139.0k | — |
| XTX Topco Ltd 0.03% of their portfolio | 71.4k $135.0k | — |
| LEVIN CAPITAL STRATEGIES, L.P. 0.02% of their portfolio | 70.0k $132.0k | — |
| BDO Wealth Advisors, LLC 0.02% of their portfolio | 70.0k $132.0k | — |