OLEMA PHARMACEUTICALS INC OLMA
COM · Common Stock · CUSIP 68062P106
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersSan Francisco, CA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($486.5k this quarter). Holder counts are more reliable. Shares outstanding: 87.5m as of 2026-08-06, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $12.51. Options: 10 managers hold calls ($6.9m notional), 9 hold puts ($4.8m).
Trends to Q2 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 73 |
| Q4 2022 | 68 |
| Q1 2023 | 67 |
| Q2 2023 | 88 |
| Q3 2023 | 98 |
| Q4 2023 | 114 |
| Q1 2024 | 127 |
| Q2 2024 | 130 |
| Q3 2024 | 132 |
| Q4 2024 | 159 |
| Q1 2025 | 136 |
| Q2 2025 | 125 |
| Q3 2025 | 128 |
| Q4 2025 | 201 |
| Q1 2026 | 196 |
| Q2 2026 | 185 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2024 | 65 | 60 |
| Q4 2024 | 82 | 48 |
| Q1 2025 | 70 | 87 |
| Q2 2025 | 74 | 57 |
| Q3 2025 | 62 | 52 |
| Q4 2025 | 133 | 52 |
| Q1 2026 | 111 | 101 |
| Q2 2026 | 96 | 94 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2025 | $5.8m | $127.3k | 0.02 |
| Q4 2025 | $30.8m | $17.5m | 0.57 |
| Q1 2026 | $41.3m | $11.1m | 0.27 |
| Q2 2026 | $6.9m | $4.8m | 0.71 |
Biggest buyers
| FMR LLC | Added | +1.8m |
| Deep Track Capital, LP | New | +1.5m |
| FRANKLIN RESOURCES INC | Added | +1.1m |
| VANGUARD PORTFOLIO MANAGEMENT LLC | Added | +1.1m |
| BlackRock, Inc. | Added | +1.1m |
| Point72 Asset Management, L.P. | Added | +999.8k |
| AMERIPRISE FINANCIAL INC | Added | +783.3k |
| Paradigm Biocapital Advisors LP | Added | +650.0k |
| MORGAN STANLEY | Added | +616.6k |
| READYSTATE ASSET MANAGEMENT LP | New | +593.8k |
Biggest sellers
| RA CAPITAL MANAGEMENT, L.P. | Sold out | -2.6m |
| JENNISON ASSOCIATES LLC | Sold out | -1.8m |
| Cormorant Asset Management, LP | Reduced | -1.8m |
| Polar Capital Holdings Plc | Sold out | -1.6m |
| First Turn Management, LLC | Sold out | -768.7k |
| Woodline Partners LP | Reduced | -731.0k |
| Defilade Capital Management, L.P. | Reduced | -579.8k |
| Bain Capital Life Sciences Investors, LLC | Reduced | -388.0k |
| PRICE T ROWE ASSOCIATES INC /MD/ | Reduced | -356.3k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | Sold out | -275.0k |
Biggest calls
| Ikarian Capital, LLC | Reduced | $2.5m200.0k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $1.3m103.7k shares |
| CITADEL ADVISORS LLC | Reduced | $691.8k55.3k shares |
| BOOTHBAY FUND MANAGEMENT, LLC | Reduced | $688.0k55.0k shares |
| NOMURA HOLDINGS INC | Added | $505.4k40.4k shares |
| JANE STREET GROUP, LLC | Reduced | $401.6k32.1k shares |
| Caption Management, LLC | Reduced | $375.3k30.0k shares |
| Point72 Asset Management, L.P. | Reduced | $252.7k20.2k shares |
| GROUP ONE TRADING LLC | Reduced | $92.6k7.4k shares |
| SIMPLEX TRADING, LLC | Reduced | $55.0k4.4k shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $2.3m182.3k shares |
| NOMURA HOLDINGS INC | Added | $825.7k66.0k shares |
| GROUP ONE TRADING LLC | Reduced | $452.9k36.2k shares |
| Caption Management, LLC | Reduced | $375.3k30.0k shares |
| CITADEL ADVISORS LLC | Reduced | $356.5k28.5k shares |
| JANE STREET GROUP, LLC | Reduced | $325.3k26.0k shares |
| Jefferies Financial Group Inc. | Unchanged | $187.7k15.0k shares |
| Point72 Asset Management, L.P. | New | $27.5k2.2k shares |
| SIMPLEX TRADING, LLC | Reduced | $12.5k1.0k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| FMR LLC 13G · institution +1.3 pts · filed 2026-08-06 | 13.8% |
| Paradigm Biocapital Advisors LP 13G · passive investor filed 2025-02-14 | 10.0% |
BIOTECHNOLOGY VALUE FUND L P
13D · may seek influence
filed 2026-10-16
Stated purposeItem 4 is hereby amended to add the following: Effective October 14, 2026, Dr. Gorjan Hrustanovic resigned from the Board. Dr. Hrustanovic also resigned from the Compensation Committee of the Board and the Science and Technology Committee of the Board. Dr. Hrustanovic's resignation was not the result of any disagreement with the Issuer on any matter relating to the Issuer's operations, policies or practices. Full filing |
9.8% |
| JANUS HENDERSON GROUP PLC 13G · institution -0.2 pts · filed 2026-05-15 | 8.2% |
| Bain Capital Life Sciences Opportunities IV, L.P. 13G · passive investor -1.8 pts · filed 2026-05-15 | 8.2% |
| BlackRock, Inc. 13G · institution filed 2026-07-29 | 7.1% |
| Invus Global Management, LLC 13G · passive investor new · filed 2026-03-20 | 5.1% |
Fell to 5% or below in the last year: Deep Track Capital, LP (0.0%, 2026-02-13)
Insider purchases and sales since 1 Apr 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2024 | 1 | $4.7m | 6 | $6.7m | — |
| Q1 2025 | 0 | — | 0 | — | — |
| Q2 2025 | 0 | — | 0 | — | — |
| Q3 2025 | 0 | — | 1 | $204.8k | — |
| Q4 2025 | 0 | — | 4 | $17.0m | — |
| Q1 2026 | 0 | — | 4 | $7.4m | — |
| Q2 2026 | 0 | — | 0 | — | — |
| Q3 2026 | 0 | — | 1 | $291.1k | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2026-07-24 | Harmon Cyrus Director | Sold | $146.4k12.5k shares |
| 2026-07-23 | Harmon Cyrus Director | Sold | $144.8k12.5k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2026
| Manager | Shares | Change |
|---|---|---|
| FMR LLC 0.01% of their portfolio | 12.1m $151.9m | Added +1.8m |
| Paradigm Biocapital Advisors LP 2.03% of their portfolio | 8.7m $108.5m | Added +650.0k |
| Jupiter Topco LLC 0.04% of their portfolio | 7.1m $88.8m | First filing |
| Bain Capital Life Sciences Investors, LLC 5.27% of their portfolio | 7.1m $88.6m | Reduced -388.0k |
| BlackRock, Inc. 0.00% of their portfolio | 6.7m $84.0m | Added +1.1m |
| BVF INC/IL 1.69% of their portfolio | 5.3m $66.3m | Unchanged |
| Siren, L.L.C. 1.23% of their portfolio | 4.9m $60.8m | Added +100.0k |
| STATE STREET CORP 0.00% of their portfolio | 4.3m $54.0m | Added +378.2k |
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 3.3m $41.8m | Added +257.7k |
| Logos Global Management LP 1.73% of their portfolio | 3.2m $40.1m | Unchanged |
| FRANKLIN RESOURCES INC 0.01% of their portfolio | 2.3m $29.4m | Added +1.1m |
| Cormorant Asset Management, LP 1.38% of their portfolio | 2.1m $26.9m | Reduced -1.8m |
| MORGAN STANLEY 0.00% of their portfolio | 1.8m $22.9m | Added +616.6k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 1.8m $22.8m | Added +274.6k |
| VANGUARD PORTFOLIO MANAGEMENT LLC 0.00% of their portfolio | 1.7m $20.8m | Added +1.1m |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 1.6m $19.6m | Added +522.4k |
| Deep Track Capital, LP 0.28% of their portfolio | 1.5m $18.8m | New |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 1.4m $17.7m | Added +334.1k |
| LIGHTSPEED MANAGEMENT COMPANY, L.L.C. 0.71% of their portfolio | 1.4m $17.0m | Unchanged |
| KINGDON CAPITAL MANAGEMENT, L.L.C. 2.02% of their portfolio | 1.2m $15.0m | Added +345.0k |
| TWO SIGMA INVESTMENTS, LP 0.01% of their portfolio | 1.1m $14.2m | Reduced -38.0k |
| Point72 Asset Management, L.P. 0.02% of their portfolio | 1.1m $13.4m | Added +999.8k |
| Duquesne Family Office LLC 0.28% of their portfolio | 986.8k $12.3m | Unchanged |
| Defilade Capital Management, L.P. 1.55% of their portfolio | 924.8k $11.6m | Reduced -579.8k |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 840.6k $10.5m | Added +783.3k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 826.6k $10.3m | Reduced -356.3k |
| Candriam S.C.A. 0.04% of their portfolio | 751.1k $9.4m | Reduced -8.4k |
| Woodline Partners LP 0.03% of their portfolio | 751.0k $9.4m | Reduced -731.0k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 674.9k $8.4m | Added +105.0k |
| Vivo Capital, LLC 0.77% of their portfolio | 671.8k $8.4m | Unchanged |
| Qube Research & Technologies Ltd 0.01% of their portfolio | 663.3k $8.3m | Added +350.5k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 641.8k $8.0m | Reduced -263.5k |
| Squarepoint Ops LLC 0.01% of their portfolio | 615.5k $7.7m | Reduced -123.1k |
| READYSTATE ASSET MANAGEMENT LP 0.30% of their portfolio | 593.8k $7.4m | New |
| Jones Hill Capital LP 1.53% of their portfolio | 574.2k $7.2m | New |
| Hudson Bay Capital Management LP 0.03% of their portfolio | 566.4k $7.1m | Added +411.6k |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 526.4k $6.6m | Reduced -138.2k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 518.3k $6.5m | Added +51.8k |
| Hennion & Walsh Asset Management, Inc. 0.15% of their portfolio | 420.2k $5.3m | Reduced -61.3k |
| Vestal Point Capital, LP 0.12% of their portfolio | 418.6k $5.2m | Reduced -10.0k |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 415.1k $5.2m | Added +56.7k |
| Ikarian Capital, LLC 0.78% of their portfolio | 383.3k $4.8m | Reduced -215.0k |
| SEB Asset Management AB 0.02% of their portfolio | 339.5k $4.2m | Unchanged |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 334.9k $4.2m | Reduced -173.8k |
| Fisher Asset Management, LLC 0.00% of their portfolio | 296.7k $3.7m | Reduced -3.0k |
| Rock Springs Capital Management LP 0.14% of their portfolio | 235.2k $2.9m | Added +64.8k |
| UBS Group AG 0.00% of their portfolio | 222.9k $2.8m | Reduced -162.2k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 222.2k $2.8m | Added +28.7k |
| Pier Capital, LLC 0.37% of their portfolio | 220.7k $2.8m | Added +84.6k |
| Birchview Capital, LP 1.16% of their portfolio | 199.0k $2.5m | Reduced -20.0k |
| Jump Financial, LLC 0.02% of their portfolio | 181.7k $2.3m | Reduced -271.3k |
| FIDEURAM - INTESA SANPAOLO PRIVATE BANKING S.P.A. 0.06% of their portfolio | 161.8k $2.0m | Added +45.0k |
| Nuveen, LLC 0.00% of their portfolio | 161.1k $2.0m | Reduced -117.9k |
| HighVista Strategies LLC 0.46% of their portfolio | 160.2k $2.0m | Added +42.6k |
| Susquehanna Portfolio Strategies, LLC 0.03% of their portfolio | 147.7k $1.8m | Added +33.8k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 143.3k $1.7m | Added +517 |
| BOOTHBAY FUND MANAGEMENT, LLC 0.03% of their portfolio | 142.6k $1.8m | Reduced -32.0k |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 133.2k $1.7m | Added +60.5k |
| CITIGROUP INC 0.00% of their portfolio | 125.6k $1.6m | Added +98.0k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 125.0k $1.6m | Reduced -160.9k |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 121.9k $1.5m | Added +433 |
| Invesco Ltd. 0.00% of their portfolio | 117.4k $1.5m | Reduced -13.5k |
| SCHRODER INVESTMENT MANAGEMENT GROUP 0.00% of their portfolio | 114.2k $1.4m | New |
| TD Asset Management Inc 0.00% of their portfolio | 106.2k $1.3m | Unchanged |
| Swiss National Bank 0.00% of their portfolio | 105.0k $1.3m | Added +30.4k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 102.7k $1.5m | Added +44.8k |
| Integral Health Asset Management, LLC 0.05% of their portfolio | 100.0k $1.3m | Reduced -50.0k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 99.5k $1.2m | Added +15.2k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 95.8k $1.2m | Reduced -65.6k |
| Trexquant Investment LP 0.01% of their portfolio | 92.4k $1.2m | Reduced -232.8k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 90.0k $1.1m | Reduced -19.6k |
| XTX Topco Ltd 0.01% of their portfolio | 89.5k $1.1m | Reduced -33.7k |
| ALPS ADVISORS INC 0.01% of their portfolio | 88.6k $1.1m | Added +24.6k |
| VICTORY CAPITAL MANAGEMENT INC 0.00% of their portfolio | 82.0k $1.0m | Reduced -121.9k |
| ALGERT GLOBAL LLC 0.01% of their portfolio | 80.9k $1.0m | Added +45.0k |
| Tidal Investments LLC 0.00% of their portfolio | 79.8k $997.8k | Reduced -5.4k |
| Tema ETFs LLC 0.03% of their portfolio | 79.8k $997.8k | First filing |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 78.2k $977.8k | Reduced -11.4k |
| FEDERATED HERMES, INC. 0.00% of their portfolio | 77.3k $966.6k | Added +63.2k |
| Rafferty Asset Management, LLC 0.00% of their portfolio | 75.5k $944.8k | Reduced -56.0k |
| Creative Planning 0.00% of their portfolio | 70.3k $879.0k | Reduced -2.0k |
| ExodusPoint Capital Management, LP 0.01% of their portfolio | 70.1k $877.5k | New |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 67.7k $846.5k | Added +21.2k |
| Connor, Clark & Lunn Investment Management Ltd. 0.00% of their portfolio | 66.2k $827.7k | Reduced -4.5k |
| PRUDENTIAL FINANCIAL INC 0.00% of their portfolio | 60.1k $751.4k | Reduced -50.1k |
| LPL Financial LLC 0.00% of their portfolio | 58.9k $737.4k | Added +1.5k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 58.5k $732.3k | Added +19.5k |
| Quantinno Capital Management LP 0.00% of their portfolio | 55.9k $699.0k | Reduced -39.5k |
| D. E. Shaw & Co., Inc. 0.00% of their portfolio | 55.5k $694.5k | Added +16.3k |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC 0.01% of their portfolio | 55.1k $689.6k | New |
| Swedbank AB 0.00% of their portfolio | 55.1k $689.3k | Unchanged |
| Engineers Gate Manager LP 0.01% of their portfolio | 53.6k $670.0k | Reduced -16.9k |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. 0.00% of their portfolio | 50.0k $626.0k | Unchanged |
| PORTLAND INVESTMENT COUNSEL INC. 0.17% of their portfolio | 50.0k $625.5k | Unchanged |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 49.1k $614.7k | Added +24.1k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 46.5k $581.7k | Added +8.0k |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ 0.00% of their portfolio | 45.2k $565.6k | Reduced -1.8k |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 44.9k $558.6k | Added +2.8k |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 41.8k $523.0k | Added +35.2k |
| Headlands Technologies LLC 0.05% of their portfolio | 41.2k $515.9k | Reduced -18.1k |