ODYSSEY THERAPEUTICS INC ODTX
COMMON STOCK · Common Stock · CUSIP 67613T104
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersBoston, MA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Shares outstanding: 48.0m as of 2026-06-12, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $18.71.
Biggest buyers
| FMR LLC | New | +5.2m |
| SR One Capital Management, LP | New | +3.8m |
| TPG GP A, LLC | New | +3.7m |
| LIGHTSPEED MANAGEMENT COMPANY, L.L.C. | New | +3.6m |
| ORBIMED ADVISORS LLC | New | +3.0m |
| Sanofi | New | +2.0m |
| DEERFIELD MANAGEMENT COMPANY, L.P. | New | +1.0m |
| Sands Capital Alternatives, LLC | New | +875.0k |
| HHLR ADVISORS, LTD. | New | +831.7k |
| General Catalyst Group Management, LLC | New | +810.3k |
Biggest sellers
| None |
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| FMR LLC 13G · institution new · filed 2026-06-05 | 10.2% |
SR ONE CAPITAL MANAGEMENT, LLC
13D · may seek influence
new · filed 2026-05-18
Stated purposeThe Funds acquired their respective shares for investment purposes. Depending on market conditions, its continuing evaluation of the business and prospects of the Issuer and other factors, the Funds and other Reporting Persons may dispose of or acquire additional shares of the Issuer. Except as set forth above, none of the Reporting Persons has any present plans which relate to or would result in: (a) The acquisition by any person of additional securities of the Issuer, or the disposition of securities of the Issuer; (b) An extraordinary corporate transaction, such as a merger, reorganization or liquidation, involving the Issuer or any of its subsidiaries; (c) A sale or transfer of a material amount of assets of the Issuer or any of its subsidiaries; (d) Any change in the present board… Full filing |
8.0% |
TPG GP A, LLC
13D · may seek influence
new · filed 2026-05-18
Stated purposeThe information set forth in or incorporated by reference in Items 2, 3, 5 and 6 of this Schedule 13D is incorporated by reference in its entirety into this Item 4. Share Purchase Agreement TPG Orazio II entered into a Share Purchase Agreement (the "Share Purchase Agreement") with the Issuer, dated as of May 7, 2026, pursuant to which it agreed to purchase, and the Issuer agreed to sell, $25,000,002 in shares of Common Stock at the $18.00 price per share of Common Stock at which shares were sold to the public in the Issuer's initial public offering (the "Concurrent Private Placement"). On May 11, 2026, the Concurrent Private Placement closed (the "Closing"), with the Issuer issuing to TPG Orazio II 1,388,889 shares of Common Stock. The aggregate purchase price of $25,000,002 paid by TP… Full filing |
7.8% |
Jeito II S.L.P.
13D · may seek influence
new · filed 2026-05-15
Stated purposeJeito II S.L.P. acquired the shares of common stock as described in this Schedule 13D for investment purposes in the regular course of its business. Jeito Capital SAS, as the management company of Jeito II S.L.P., may be deemed to be a beneficial owner, for purposes of Section 13(d) of the Securities Exchange Act of 1934, as amended (the "Act"), of any securities held by Jeito II S.L.P. Rafaele Tordjman, as Chief Executive Officer of Jeito Capital SAS, and Sabine Dandiguian, as Managing Director of Jeito Capital SAS, may be deemed to be beneficial owners, for purposes of Section 13(d) of the Act, of any securities of the Issuer beneficially owned by Jeito Capital SAS. The Reporting Persons intend to review their investment in the Issuer on a continuing basis. Depending on market conditions… Full filing |
7.8% |
| Lightspeed Venture Partners XV-B (Ignite), L.P. 13G · passive investor new · filed 2026-05-18 | 7.6% |
Dimension Capital II, L.P.
13D · may seek influence
new · filed 2026-05-15
Stated purposeThe Reporting Persons acquired the Common Stock set forth in this Schedule 13D and hold their shares of Common Stock for investment purposes. Nan Li currently serves as a member of the Issuer's Board of Directors. Each Reporting Person expects to continuously review such person's investment in the Issuer and, depending on various factors including but not limited to, the price of the Common Stock, the terms and conditions of the transaction, prevailing market conditions and such other considerations as such Reporting Person deems relevant, may at any time or from time to time, and subject to any required regulatory approvals, acquire additional Common Stock, preferred stock or other securities convertible into or exercisable or exchangeable for Common Stock from time to time on the open m… Full filing |
7.1% |
Insider purchases and sales since 1 Apr 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2024 | 0 | — | 0 | — | — |
| Q1 2025 | 0 | — | 0 | — | — |
| Q2 2025 | 0 | — | 0 | — | — |
| Q3 2025 | 0 | — | 0 | — | — |
| Q4 2025 | 0 | — | 0 | — | — |
| Q1 2026 | 0 | — | 0 | — | — |
| Q2 2026 | 5 | $40.3m | 0 | — | — |
| Q3 2026 | 0 | — | 0 | — | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2026-05-11 | COULTER JAMES G +2 Former 10% Owner · See Explanation of Responses | Bought | $25.0m1.4m shares |
| 2026-05-11 | Li Nan (LN) Director · See footnote | Bought | $20.0m1.1m shares |
| 2026-05-11 | George Simeon +1 10% owner · See Note 2 | Bought | $4.0m222.2k shares |
| 2026-05-11 | George Simeon +1 10% owner · See Note 12 | Bought | $3.6m200.0k shares |
| 2026-05-11 | George Simeon +1 10% owner · See Note 10 | Bought | $2.4m133.3k shares |
| 2026-05-11 | Chu Shelley Director | Bought | $200.0k11.1k shares |
| 2026-05-11 | George Simeon +1 10% owner · See Note 2 | Sold | $19.2k1.1k shares |
| 2026-05-11 | George Simeon +1 10% owner · See Note 12 | Sold | $7.9k438 shares |
| 2026-05-11 | George Simeon +1 10% owner · See Note 10 | Sold | $5.0k277 shares |
| 2026-05-08 | Dimension Capital II, L.P. Director | Bought | $20.0m1.1m shares |
| 2026-05-08 | LEIDEN JEFFREY M Director | Bought | $100.0k5.0k shares |
| 2026-05-08 | Haas Jason Chief Financial Officer | Bought | $20.0k1.0k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2026
| Manager | Shares | Change |
|---|---|---|
| FMR LLC 0.00% of their portfolio | 5.2m $96.9m | New |
| SR One Capital Management, LP 6.83% of their portfolio | 3.8m $71.0m | New |
| TPG GP A, LLC 1.38% of their portfolio | 3.7m $69.0m | New |
| LIGHTSPEED MANAGEMENT COMPANY, L.L.C. 2.81% of their portfolio | 3.6m $67.5m | New |
| ORBIMED ADVISORS LLC 1.06% of their portfolio | 3.0m $56.2m | New |
| Sanofi 6.98% of their portfolio | 2.0m $37.3m | New |
| DEERFIELD MANAGEMENT COMPANY, L.P. 0.20% of their portfolio | 1.0m $19.6m | New |
| Sands Capital Alternatives, LLC 2.67% of their portfolio | 875.0k $16.4m | New |
| HHLR ADVISORS, LTD. 1.87% of their portfolio | 831.7k $15.6m | New |
| General Catalyst Group Management, LLC 8.04% of their portfolio | 810.3k $15.2m | New |
| Affinity Asset Advisors, LLC 0.70% of their portfolio | 766.3k $14.3m | New |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.02% of their portfolio | 725.0k $13.6m | New |
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 720.4k $13.5m | New |
| Foresite Capital Management V, LLC 3.68% of their portfolio | 713.1k $13.3m | New |
| Vivo Capital, LLC 0.98% of their portfolio | 575.0k $10.8m | New |
| EcoR1 Capital, LLC 0.52% of their portfolio | 555.6k $10.4m | New |
| Logos Global Management LP 0.42% of their portfolio | 521.7k $9.8m | New |
| MARSHALL WACE, LLP 0.01% of their portfolio | 492.7k $9.2m | New |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 472.0k $8.8m | New |
| Catalio Capital Management, LP 1.61% of their portfolio | 457.8k $8.6m | New |
| Redmile Group, LLC 0.53% of their portfolio | 425.0k $8.0m | New |
| Balyasny Asset Management L.P. 0.01% of their portfolio | 393.9k $7.4m | New |
| Woodline Partners LP 0.02% of their portfolio | 345.7k $6.5m | New |
| FRANKLIN RESOURCES INC 0.00% of their portfolio | 275.0k $5.1m | New |
| Boxer Capital Management, LLC 0.39% of their portfolio | 275.0k $5.1m | New |
| BlackRock, Inc. 0.00% of their portfolio | 240.7k $4.5m | New |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 222.4k $4.2m | New |
| Siren, L.L.C. 0.08% of their portfolio | 200.0k $3.7m | New |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 189.5k $3.5m | New |
| Cormorant Asset Management, LP 0.17% of their portfolio | 175.0k $3.3m | New |
| Aberdeen Group plc 0.00% of their portfolio | 165.0k $3.1m | New |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 156.6k $2.9m | New |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 132.8k $2.5m | New |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 101.5k $1.9m | New |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 100.9k $1.9m | New |
| Hudson Bay Capital Management LP 0.01% of their portfolio | 72.9k $1.4m | New |
| UBS Group AG 0.00% of their portfolio | 68.8k $1.3m | New |
| Ensign Peak Advisors, Inc 0.00% of their portfolio | 64.6k $1.2m | New |
| SEVEN GRAND MANAGERS, LLC 0.04% of their portfolio | 50.0k $935.5k | New |
| Eversept Partners, LP 0.05% of their portfolio | 49.7k $929.1k | New |
| TUDOR INVESTMENT CORP ET AL 0.00% of their portfolio | 44.2k $826.4k | New |
| NORTHERN TRUST CORP 0.00% of their portfolio | 34.6k $647.1k | New |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 32.1k $601.1k | New |
| TD Asset Management Inc 0.00% of their portfolio | 29.1k $545.1k | New |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 27.8k $524.9k | New |
| Ghisallo Capital Management LLC 0.01% of their portfolio | 25.0k $467.8k | New |
| Burkehill Global Management, LP 0.01% of their portfolio | 20.0k $374.2k | New |
| D. E. Shaw & Co., Inc. 0.00% of their portfolio | 19.8k $371.4k | New |
| XTX Topco Ltd 0.00% of their portfolio | 16.6k $309.7k | New |
| VANGUARD PORTFOLIO MANAGEMENT LLC 0.00% of their portfolio | 13.7k $256.0k | New |
| Vanguard Global Advisers, LLC 0.00% of their portfolio | 7.9k $148.7k | New |
| Omega Fund Management, LLC 0.03% of their portfolio | 2.9k $54.1k | New |
| Legal & General Group Plc 0.00% of their portfolio | 2.0k $37.3k | New |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 1.8k $33.6k | New |
| MORGAN STANLEY 0.00% of their portfolio | 1.8k $33.2k | New |
| BARCLAYS PLC 0.00% of their portfolio | 1.5k $27.3k | New |
| CITIGROUP INC 0.00% of their portfolio | 511 $9.6k | New |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 193 $3.6k | New |