NEXTCURE INC NXTC
COM NEW · Common Stock · CUSIP 65343E207
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersBaltimore, MD
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Shares outstanding: 4.6m as of 2026-07-31, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $1.60.
Trends to Q2 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2025 | 16 |
| Q4 2025 | 24 |
| Q1 2026 | 26 |
| Q2 2026 | 30 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2025 | 14 | 6 |
| Q1 2026 | 8 | 8 |
| Q2 2026 | 19 | 12 |
Biggest buyers
| ADAGE CAPITAL PARTNERS GP, L.L.C. | New | +277.2k |
| RENAISSANCE TECHNOLOGIES LLC | Added | +110.7k |
| MILLENNIUM MANAGEMENT LLC | New | +88.1k |
| Ikarian Capital, LLC | Added | +50.0k |
| HRT FINANCIAL LP | New | +36.5k |
| JANE STREET GROUP, LLC | New | +32.7k |
| Verdad Advisers, LP | Added | +17.5k |
| BOOTHBAY FUND MANAGEMENT, LLC | Added | +15.1k |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | New | +12.5k |
| Virtu Financial LLC | New | +11.0k |
Biggest sellers
| Squadron Capital Management LLC | Reduced | -200.5k |
| Affinity Asset Advisors, LLC | Reduced | -199.9k |
| SILVERARC CAPITAL MANAGEMENT, LLC | Sold out | -176.1k |
| Opaleye Management Inc. | Sold out | -141.2k |
| AWM Investment Company, Inc. | Sold out | -117.4k |
| Exome Asset Management LLC | Sold out | -115.5k |
| Pfizer Inc | Reduced | -109.0k |
| Woodline Partners LP | Sold out | -27.5k |
| CITADEL ADVISORS LLC | Sold out | -15.3k |
| VANGUARD CAPITAL MANAGEMENT LLC | Reduced | -3.6k |
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| ADAR1 Capital Management, LLC 13G · institution new · filed 2026-08-14 | 15.8% |
| Ikarian Capital, LLC 13G · institution no change · filed 2026-08-14 | 10.0% |
| JP Sailing Capital Ltd 13G · institution new · filed 2026-10-20 | 9.9% |
| Simcere Zaiming, Inc. 13G · passive investor -3.3 pts · filed 2026-05-06 | 9.4% |
| Adage Capital Management, L.P. 13G · institution new · filed 2026-08-12 | 7.7% |
Sofinnova Venture Partners IX, L.P.
13D · may seek influence
filed 2026-03-05
Stated purposeThe Reporting Persons hold their securities of the Issuer for investment purposes. Depending on the factors discussed herein, the Reporting Persons may, from time to time, acquire additional Common Stock and/or retain and/or sell all or a portion of the Common Stock held by the Reporting Persons in the open market or in privately negotiated transactions, and/or may distribute the Common Stock held by the Reporting Persons to their respective members or limited partners. Any actions the Reporting Persons might undertake will be dependent upon the Reporting Persons' review of numerous factors, including, among other things, the price levels of the Common Stock, general market and economic conditions, ongoing evaluation of the Issuer's business, financial condition, operations and prospects; … Full filing |
7.1% |
| Affinity Asset Advisors, LLC 13G · institution -3.6 pts · filed 2026-08-13 | 6.4% |
Fell to 5% or below in the last year: Squadron Capital Management LLC (1.6%, 2026-08-14), SILVERARC CAPITAL MANAGEMENT, LLC (4.9%, 2026-05-13)
Insider purchases and sales since 1 Apr 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2026-08-10 | Ren Jinsheng +5 Former 10% Owner · See Footnotes | Sold | $184.8k30.0k shares |
| 2026-07-31 | Schneeberger Daniel +1 10% owner · See Footnote | Bought | $179.3k36.3k shares |
| 2026-07-30 | Schneeberger Daniel +1 10% owner · See Footnote | Bought | $1.4m292.9k shares |
| 2026-07-29 | Schneeberger Daniel +1 10% owner · See Footnote | Bought | $17.1k3.4k shares |
| 2026-07-28 | Schneeberger Daniel +1 10% owner · See Footnote | Bought | $31.7k6.4k shares |
| 2026-07-27 | Schneeberger Daniel +1 10% owner · See Footnote | Bought | $39.0k7.8k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2026
| Manager | Shares | Change |
|---|---|---|
| Ikarian Capital, LLC 0.08% of their portfolio | 288.3k $461.3k | Added +50.0k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.00% of their portfolio | 277.2k $443.5k | New |
| Sofinnova Investments, Inc. 0.02% of their portfolio | 222.7k $356.2k | Unchanged |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 171.2k $273.9k | Added +110.7k |
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 156.8k $250.9k | Reduced -3.6k |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 88.1k $141.0k | New |
| BOOTHBAY FUND MANAGEMENT, LLC 0.00% of their portfolio | 84.7k $135.5k | Added +15.1k |
| Squadron Capital Management LLC 0.04% of their portfolio | 64.5k $103.1k | Reduced -200.5k |
| Verdad Advisers, LP 0.09% of their portfolio | 60.5k $96.7k | Added +17.5k |
| Pfizer Inc 0.04% of their portfolio | 44.3k $73.0k | Reduced -109.0k |
| Affinity Asset Advisors, LLC 0.00% of their portfolio | 42.0k $67.1k | Reduced -199.9k |
| BlackRock, Inc. 0.00% of their portfolio | 37.3k $59.8k | Added +9.6k |
| HRT FINANCIAL LP 0.00% of their portfolio | 36.5k $58.0k | New |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 32.7k $52.4k | New |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 29.9k $47.9k | Reduced -1.2k |
| CARDIFF PARK ADVISORS, LLC 0.00% of their portfolio | 21.8k $34.9k | Unchanged |
| ACADIAN ASSET MANAGEMENT LLC 0.00% of their portfolio | 19.0k $30.0k | Unchanged |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 16.1k $25.8k | Added +119 |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. 0.00% of their portfolio | 12.5k $20.0k | New |
| Virtu Financial LLC 0.00% of their portfolio | 11.0k $18.0k | New |
| DIADEMA PARTNERS LP 0.00% of their portfolio | 7.7k $12.4k | New |
| BARCLAYS PLC 0.00% of their portfolio | 5.7k $9.2k | Added +100 |
| Persistent Asset Partners Ltd 0.00% of their portfolio | 2.0k $3.2k | New |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 1.7k $2.8k | New |
| UBS Group AG 0.00% of their portfolio | 594 $951 | Added +256 |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO 0.00% of their portfolio | 83 $133 | New |
| MORGAN STANLEY 0.00% of their portfolio | 66 $106 | Unchanged |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 61 $107 | Unchanged |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 32 $51 | Unchanged |
| SBI Securities Co., Ltd. 0.00% of their portfolio | 20 $32 | New |