NEUROGENE INC NGNE
COM · Common Stock · CUSIP 64135M105 · ISIN US64135M1053
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersNew York, NY
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($56.5k this quarter). Holder counts are more reliable. Shares outstanding: 20.0m as of 2026-08-07, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $31.45. Options: 3 managers hold calls ($3.8m notional), 3 hold puts ($468.6k).
Trends to Q2 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q4 2023 | 36 |
| Q1 2024 | 61 |
| Q2 2024 | 67 |
| Q3 2024 | 87 |
| Q4 2024 | 90 |
| Q1 2025 | 87 |
| Q2 2025 | 84 |
| Q3 2025 | 88 |
| Q4 2025 | 93 |
| Q1 2026 | 96 |
| Q2 2026 | 112 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2024 | 42 | 24 |
| Q4 2024 | 53 | 42 |
| Q1 2025 | 43 | 39 |
| Q2 2025 | 36 | 41 |
| Q3 2025 | 40 | 35 |
| Q4 2025 | 37 | 36 |
| Q1 2026 | 58 | 31 |
| Q2 2026 | 60 | 35 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2025 | $1.9m | $283.7k | 0.15 |
| Q4 2025 | $206.0k | $39.1k | 0.19 |
| Q1 2026 | $3.4m | $832.6k | 0.24 |
| Q2 2026 | $3.8m | $468.6k | 0.12 |
Biggest buyers
| FRANKLIN RESOURCES INC | New | +204.3k |
| Point72 Asset Management, L.P. | New | +141.9k |
| MOORE CAPITAL MANAGEMENT, LP | New | +141.6k |
| Casdin Capital, LLC | Added | +125.0k |
| Driehaus Capital Management LLC | Added | +110.8k |
| Balyasny Asset Management L.P. | Added | +100.3k |
| Trexquant Investment LP | New | +73.8k |
| BlackRock, Inc. | Added | +52.9k |
| DAFNA Capital Management LLC | Added | +32.4k |
| WELLINGTON MANAGEMENT GROUP LLP | New | +31.4k |
Biggest sellers
| ArrowMark Colorado Holdings LLC | Reduced | -182.3k |
| MILLENNIUM MANAGEMENT LLC | Reduced | -162.1k |
| GREAT POINT PARTNERS LLC | Reduced | -147.8k |
| MORGAN STANLEY | Reduced | -93.5k |
| STATE STREET CORP | Reduced | -88.7k |
| FMR LLC | Reduced | -87.1k |
| Trails Edge Capital Partners, LP | Reduced | -67.9k |
| Redmile Group, LLC | Reduced | -47.4k |
| RENAISSANCE TECHNOLOGIES LLC | Reduced | -23.0k |
| BLAIR WILLIAM & CO/IL | Reduced | -21.3k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $2.9m92.4k shares |
| CITADEL ADVISORS LLC | Added | $839.7k26.7k shares |
| SIMPLEX TRADING, LLC | Reduced | $47.2k1.5k shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $462.3k14.7k shares |
| GROUP ONE TRADING LLC | Unchanged | $3.1k100 shares |
| SIMPLEX TRADING, LLC | Reduced | $3.1k100 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| PRUDENTIAL FINANCIAL INC 13G · institution new · filed 2026-10-07 | 11.2% |
| JENNISON ASSOCIATES LLC 13G · institution new · filed 2026-10-06 | 11.1% |
| RTW INVESTMENTS, LP 13G · institution filed 2025-02-14 | 10.0% |
| Redmile Group, LLC 13G · institution no change · filed 2026-08-14 | 9.9% |
| EcoR1 Capital, LLC 13G · institution filed 2025-11-14 | 9.9% |
| Casdin Capital, LLC 13G · passive investor filed 2025-02-14 | 8.7% |
| BAKER BROS. ADVISORS LP 13G · institution -3.0 pts · filed 2025-08-14 | 7.0% |
| BlackRock, Inc. 13G · institution filed 2025-04-23 | 6.8% |
| BALYASNY ASSET MANAGEMENT L.P. 13G · institution new · filed 2026-08-14 | 5.2% |
Fell to 5% or below in the last year: Trails Edge Capital Partners, LP (4.5%, 2026-08-14)
Insider purchases and sales since 1 Apr 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2024 | 2 | $1.5m | 0 | — | — |
| Q1 2025 | 0 | — | 1 | $76.2k | $76.2k |
| Q2 2025 | 0 | — | 1 | $103.0k | $103.0k |
| Q3 2025 | 0 | — | 0 | — | — |
| Q4 2025 | 0 | — | 0 | — | — |
| Q1 2026 | 0 | — | 4 | $493.6k | $493.6k |
| Q2 2026 | 0 | — | 1 | $300.0k | $300.0k |
| Q3 2026 | 0 | — | 1 | $340.0k | $340.0k |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2026-07-07 | Cvijic Christine Mikail President and CFO, director | Sold plan | $151.7k4.2k shares |
| 2026-07-06 | Cvijic Christine Mikail President and CFO, director | Sold plan | $21.6k600 shares |
| 2026-07-02 | Cvijic Christine Mikail President and CFO, director | Sold plan | $141.4k4.1k shares |
| 2026-07-01 | Cvijic Christine Mikail President and CFO, director | Sold plan | $25.2k739 shares |
| 2026-05-06 | Cvijic Christine Mikail President and CFO, director | Sold plan | $300.0k9.6k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2026
| Manager | Shares | Change |
|---|---|---|
| SAMSARA BIOCAPITAL, LLC 4.44% of their portfolio | 1.7m $54.0m | Unchanged |
| Casdin Capital, LLC 2.43% of their portfolio | 1.5m $48.6m | Added +125.0k |
| Redmile Group, LLC 2.98% of their portfolio | 1.4m $44.4m | Reduced -47.4k |
| RTW INVESTMENTS, LP 0.37% of their portfolio | 1.4m $42.8m | Unchanged |
| EcoR1 Capital, LLC 1.98% of their portfolio | 1.3m $40.0m | Unchanged |
| BlackRock, Inc. 0.00% of their portfolio | 1.1m $33.3m | Added +52.9k |
| BAKER BROS. ADVISORS LP 0.16% of their portfolio | 991.7k $31.2m | Unchanged |
| Balyasny Asset Management L.P. 0.05% of their portfolio | 818.7k $25.7m | Added +100.3k |
| Trails Edge Capital Partners, LP 3.57% of their portfolio | 714.9k $22.5m | Reduced -67.9k |
| TORONTO DOMINION BANK 0.04% of their portfolio | 681.3k $21.4m | Unchanged |
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 536.5k $16.9m | Added +21.8k |
| JENNISON ASSOCIATES LLC 0.01% of their portfolio | 518.6k $16.3m | Reduced -9.1k |
| CITADEL ADVISORS LLC 0.01% of their portfolio | 409.0k $12.9m | Added +22.0k |
| GREAT POINT PARTNERS LLC 2.61% of their portfolio | 352.2k $11.1m | Reduced -147.8k |
| ArrowMark Colorado Holdings LLC 0.45% of their portfolio | 342.5k $10.8m | Reduced -182.3k |
| FMR LLC 0.00% of their portfolio | 295.6k $9.3m | Reduced -87.1k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 293.2k $9.2m | Added +14.2k |
| STATE STREET CORP 0.00% of their portfolio | 224.3k $7.1m | Reduced -88.7k |
| FRANKLIN RESOURCES INC 0.00% of their portfolio | 204.3k $6.4m | New |
| MORGAN STANLEY 0.00% of their portfolio | 191.7k $6.0m | Reduced -93.5k |
| UBS Group AG 0.00% of their portfolio | 171.3k $5.4m | Reduced -14.4k |
| BLAIR WILLIAM & CO/IL 0.01% of their portfolio | 146.9k $4.6m | Reduced -21.3k |
| Driehaus Capital Management LLC 0.03% of their portfolio | 143.5k $4.5m | Added +110.8k |
| Point72 Asset Management, L.P. 0.01% of their portfolio | 141.9k $4.5m | New |
| MOORE CAPITAL MANAGEMENT, LP 0.10% of their portfolio | 141.6k $4.5m | New |
| Rock Springs Capital Management LP 0.16% of their portfolio | 106.8k $3.4m | Added +2.4k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 106.7k $3.4m | Added +405 |
| NORTHERN TRUST CORP 0.00% of their portfolio | 103.6k $3.3m | Added +6.0k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 101.3k $3.2m | Reduced -6.4k |
| VANGUARD PORTFOLIO MANAGEMENT LLC 0.00% of their portfolio | 95.6k $3.0m | Added +30.5k |
| DAFNA Capital Management LLC 0.53% of their portfolio | 89.0k $2.8m | Added +32.4k |
| Woodline Partners LP 0.01% of their portfolio | 83.8k $2.6m | Unchanged |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 74.3k $2.3m | Added +4.5k |
| Trexquant Investment LP 0.01% of their portfolio | 73.8k $2.3m | New |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 61.9k $2.0m | Reduced -3.0k |
| XTX Topco Ltd 0.02% of their portfolio | 55.4k $1.7m | Added +28.0k |
| SCHRODER INVESTMENT MANAGEMENT GROUP 0.00% of their portfolio | 52.3k $1.7m | Unchanged |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 42.7k $1.3m | Reduced -162.1k |
| Raiffeisen Bank International AG 0.01% of their portfolio | 34.0k $1.1m | Reduced -9.0k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 32.7k $1.0m | Added +2.7k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 32.6k $1.0m | Added +21.2k |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 31.4k $987.3k | New |
| Bank of New York Mellon Corp 0.00% of their portfolio | 28.7k $903.9k | Added +2.7k |
| Nuveen, LLC 0.00% of their portfolio | 27.8k $875.1k | Added +2.6k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 26.1k $820.5k | New |
| Quadrature Capital Ltd 0.01% of their portfolio | 24.3k $764.9k | New |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 23.3k $733.7k | Added +4.8k |
| Seven Fleet Capital Management LP 0.11% of their portfolio | 22.1k $693.8k | New |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 20.4k $641.7k | Reduced -23.0k |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.01% of their portfolio | 18.8k $590.7k | Unchanged |
| ALPS ADVISORS INC 0.00% of their portfolio | 16.0k $504.5k | Added +3.4k |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 15.1k $473.7k | Added +4.8k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 14.2k $445.1k | Added +261 |
| LOS ANGELES CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 13.8k $434.1k | Added +10 |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 13.8k $277.6k | Added +3.2k |
| Mariner, LLC 0.00% of their portfolio | 12.3k $385.6k | Reduced -4.4k |
| Virtus Investment Advisers, LLC 0.08% of their portfolio | 11.2k $353.6k | Reduced -1.8k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 11.1k $349.9k | Added +260 |
| Creative Planning 0.00% of their portfolio | 10.6k $332.8k | New |
| D. E. Shaw & Co., Inc. 0.00% of their portfolio | 9.8k $307.6k | New |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 9.5k $297.9k | Added +5.2k |
| Pale Fire Capital SE 0.02% of their portfolio | 9.5k $297.5k | New |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 8.9k $280.0k | New |
| Brevan Howard Capital Management LP 0.00% of their portfolio | 8.4k $263.8k | Reduced -4.4k |
| CITIGROUP INC 0.00% of their portfolio | 7.9k $247.4k | Added +6.9k |
| ADAR1 Capital Management, LLC 0.01% of their portfolio | 7.8k $245.3k | New |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 0.00% of their portfolio | 7.5k $235.6k | New |
| Invesco Ltd. 0.00% of their portfolio | 6.7k $209.4k | New |
| Mitsubishi UFJ Asset Management Co., Ltd. 0.00% of their portfolio | 6.1k $191.5k | Reduced -1.9k |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 6.0k $188.4k | Added +4.4k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 5.9k $186.6k | Unchanged |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 5.2k $163.8k | Reduced -100 |
| Vanguard Global Advisers, LLC 0.00% of their portfolio | 4.9k $152.7k | Unchanged |
| PNC Financial Services Group, Inc. 0.00% of their portfolio | 4.5k $141.6k | Reduced -546 |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 4.2k $132.1k | Unchanged |
| Police & Firemen's Retirement System of New Jersey 0.00% of their portfolio | 3.8k $121.0k | Unchanged |
| NATIXIS 0.00% of their portfolio | 3.7k $117.0k | New |
| BARCLAYS PLC 0.00% of their portfolio | 3.3k $104.1k | Added +559 |
| China Universal Asset Management Co., Ltd. 0.00% of their portfolio | 2.5k $79.1k | Reduced -234 |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 2.4k $76.0k | Added +2.3k |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 1.9k $59.7k | Reduced -796 |
| Legal & General Group Plc 0.00% of their portfolio | 1.1k $34.5k | Added +200 |
| Ameritas Investment Partners, Inc. 0.00% of their portfolio | 1.0k $31.7k | Unchanged |
| State of Wyoming 0.00% of their portfolio | 980 $30.8k | New |
| Arax Advisory Partners 0.00% of their portfolio | 906 $28.5k | Added +892 |
| Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio | 707 $22.2k | Reduced -101 |
| GAMMA Investing LLC 0.00% of their portfolio | 545 $17.1k | Added +10 |
| NISA INVESTMENT ADVISORS, LLC 0.00% of their portfolio | 463 $14.6k | Added +400 |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 440 $13.8k | Reduced -839 |
| GF FUND MANAGEMENT CO. LTD. 0.00% of their portfolio | 332 $10.4k | Reduced -8 |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 292 $9.2k | Unchanged |
| Rockefeller Capital Management L.P. 0.00% of their portfolio | 231 $7.3k | New |
| Sterling Capital Management LLC 0.00% of their portfolio | 228 $7.2k | Reduced -146 |
| Farther Finance Advisors, LLC 0.00% of their portfolio | 176 $5.6k | Added +6 |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 156 $4.9k | Reduced -448 |
| US BANCORP \DE\ 0.00% of their portfolio | 147 $4.6k | Added +117 |
| SBI Securities Co., Ltd. 0.00% of their portfolio | 125 $3.9k | Unchanged |
| Integrated Wealth Concepts LLC 0.00% of their portfolio | 105 $3.3k | New |
| ROTHSCHILD INVESTMENT LLC 0.00% of their portfolio | 53 $1.7k | Added +8 |
| Truvestments Capital LLC 0.00% of their portfolio | 46 $1.4k | Unchanged |