MIRUM PHARMACEUTICALS INC MIRM
COM · Common Stock · CUSIP 604749101 · ISIN US6047491013
Biopharmaceutical company
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersFoster City, CA
- Founded2018
- Websitemirumpharma.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($372.4k this quarter). Holder counts are more reliable. Shares outstanding: 38.3m as of 2023-07-28, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $25.87. Options: 4 managers hold calls ($486.2k notional), 5 hold puts ($1.3m).
Trends to Q2 2023
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 112 |
| Q4 2022 | 105 |
| Q1 2023 | 119 |
| Q2 2023 | 148 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 61 | 49 |
| Q1 2023 | 64 | 40 |
| Q2 2023 | 95 | 37 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2022 | $374.0k | $10.0k | 0.03 |
| Q4 2022 | $422.2k | $137.5k | 0.33 |
| Q1 2023 | $10.3m | $84.1k | 0.01 |
| Q2 2023 | $486.2k | $1.3m | 2.74 |
Biggest buyers
| EVENTIDE ASSET MANAGEMENT, LLC | Added | +1.4m |
| Nicholas Investment Partners, LP | New | +915.1k |
| CADIAN CAPITAL MANAGEMENT, LP | Added | +530.0k |
| Frazier Life Sciences Management, L.P. | Added | +500.0k |
| WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC | New | +337.4k |
| STATE STREET CORP | Added | +324.0k |
| VANGUARD GROUP INC | Added | +320.8k |
| BlackRock Inc. | Added | +320.5k |
| Penn Capital Management Company, LLC | New | +239.3k |
| WASATCH ADVISORS LP | New | +230.5k |
Biggest sellers
| DEERFIELD MANAGEMENT COMPANY, L.P. | Sold out | -2.0m |
| NEA Management Company, LLC | Reduced | -2.0m |
| AXA S.A. | Reduced | -219.7k |
| Woodline Partners LP | Reduced | -196.1k |
| WELLINGTON MANAGEMENT GROUP LLP | Sold out | -154.8k |
| GOLDMAN SACHS GROUP INC | Reduced | -117.5k |
| SPHERA FUNDS MANAGEMENT LTD. | Sold out | -109.3k |
| Lion Point Capital, LP | Reduced | -70.0k |
| Soleus Capital Management, L.P. | Reduced | -66.0k |
| Affinity Asset Advisors, LLC | Reduced | -65.0k |
Biggest calls
| CITADEL ADVISORS LLC | Reduced | $380.3k14.7k shares |
| GROUP ONE TRADING LLC | Added | $56.9k2.2k shares |
| SIMPLEX TRADING, LLC | Reduced | $49.0k1.9k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| WOLVERINE ASSET MANAGEMENT LLC | New | $540.7k20.9k shares |
| JANE STREET GROUP, LLC | New | $349.2k13.5k shares |
| CITADEL ADVISORS LLC | Added | $282.0k10.9k shares |
| SIMPLEX TRADING, LLC | New | $160.0k6.2k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| Janus Henderson Group Ltd. 13G · institution -2.1 pts · filed 2026-08-13 | 9.7% |
Frazier Life Sciences IX, L.P.
13D · may seek influence
-0.8 pts · filed 2026-01-27
Stated purposeItem 4 is hereby amended and restated in its entirety to read as follows: Each of FLS IX, FLS X, FLSPF, FLS XI and FLS XII acquired the FLS IX Shares, the FLS X Shares, the FLSPF Shares, the FLS XI Shares and the FLS XII Shares, as the case may be, for investment purposes. Depending on market conditions, its continuing evaluation of the business and prospects of the Issuer and other factors, FLS IX, FLS X, FLSPF, FLS XI and FLS XII and the other Reporting Persons may dispose of or acquire additional shares of the Issuer. Except as set forth above, none of the Reporting Persons has any present plans which relate to or would result in: (a) The acquisition by any person of additional securities of the Issuer, or the disposition of securities of the Issuer; (b) An extraordinary corporat… Full filing |
6.8% |
| FMR LLC 13G · institution new · filed 2026-08-06 | 6.2% |
| BlackRock, Inc. 13G · institution filed 2026-04-27 | 5.7% |
Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-27), EVENTIDE ASSET MANAGEMENT, LLC (4.1%, 2026-02-13)
Insider purchases and sales in Q2 2023
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q3 2021 | 0 | — | 0 | — | — |
| Q4 2021 | 2 | $121.3k | 6 | $145.8k | — |
| Q1 2022 | 0 | — | 0 | — | — |
| Q2 2022 | 0 | — | 0 | — | — |
| Q3 2022 | 0 | — | 0 | — | — |
| Q4 2022 | 0 | — | 1 | $6.0m | — |
| Q1 2023 | 0 | — | 4 | $155.5k | — |
| Q2 2023 | 0 | — | 1 | $832.7k | $832.7k |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2023-06-08 | GREY MICHAEL G Director | Sold plan | $423.6k14.6k shares |
| 2023-05-03 | GREY MICHAEL G Director | Sold plan | $409.0k14.6k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2023
| Manager | Shares | Change |
|---|---|---|
| Frazier Life Sciences Management, L.P. 6.74% of their portfolio | 4.4m $112.8m | Added +500.0k |
| EVENTIDE ASSET MANAGEMENT, LLC 1.51% of their portfolio | 3.5m $89.5m | Added +1.4m |
| NEA Management Company, LLC 4.32% of their portfolio | 2.2m $56.6m | Reduced -2.0m |
| BlackRock Inc. 0.00% of their portfolio | 2.0m $52.5m | Added +320.5k |
| Rock Springs Capital Management LP 1.12% of their portfolio | 1.8m $47.1m | Added +25.0k |
| NOVO HOLDINGS A/S 3.37% of their portfolio | 1.7m $43.6m | Unchanged |
| RiverVest Venture Management LLC 46.52% of their portfolio | 1.6m $41.9m | Unchanged |
| VANGUARD GROUP INC 0.00% of their portfolio | 1.6m $41.3m | Added +320.8k |
| STATE STREET CORP 0.00% of their portfolio | 1.5m $38.7m | Added +324.0k |
| CITADEL ADVISORS LLC 0.04% of their portfolio | 1.4m $37.0m | Added +60.5k |
| CADIAN CAPITAL MANAGEMENT, LP 1.55% of their portfolio | 1.3m $32.7m | Added +530.0k |
| TANG CAPITAL MANAGEMENT LLC 4.33% of their portfolio | 1.1m $29.4m | Reduced -32.9k |
| Polar Capital Holdings Plc 0.16% of their portfolio | 925.0k $23.9m | Reduced -4.9k |
| Nicholas Investment Partners, LP 1.62% of their portfolio | 915.1k $23.7m | New |
| PICTET ASSET MANAGEMENT SA 0.03% of their portfolio | 884.0k $22.9m | Added +79.8k |
| Prosight Management, LP 5.11% of their portfolio | 675.0k $17.5m | Added +107.2k |
| AXA S.A. 0.06% of their portfolio | 668.9k $17.3m | Reduced -219.7k |
| FRANKLIN RESOURCES INC 0.01% of their portfolio | 611.1k $15.8m | Added +210.6k |
| PERCEPTIVE ADVISORS LLC 0.45% of their portfolio | 601.6k $15.6m | Unchanged |
| Point72 Asset Management, L.P. 0.05% of their portfolio | 601.0k $15.5m | Added +43.6k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 525.6k $13.6m | Added +107.3k |
| WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC 0.03% of their portfolio | 337.4k $8.7m | New |
| Woodline Partners LP 0.10% of their portfolio | 327.8k $8.5m | Reduced -196.1k |
| BARCLAYS PLC 0.00% of their portfolio | 287.1k $7.4m | Reduced -12.3k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 274.9k $7.1m | Reduced -117.5k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 273.9k $7.1m | Added +59.7k |
| JANUS HENDERSON GROUP PLC 0.00% of their portfolio | 265.6k $6.9m | Added +224.3k |
| JANE STREET GROUP, LLC 0.01% of their portfolio | 247.7k $6.4m | Added +202.4k |
| Penn Capital Management Company, LLC 0.60% of their portfolio | 239.3k $6.2m | New |
| SILVERCREST ASSET MANAGEMENT GROUP LLC 0.04% of their portfolio | 234.3k $6.1m | Added +32.9k |
| WASATCH ADVISORS LP 0.04% of their portfolio | 230.5k $6.0m | New |
| Ensign Peak Advisors, Inc 0.01% of their portfolio | 225.7k $5.8m | Unchanged |
| NEW YORK STATE COMMON RETIREMENT FUND 0.01% of their portfolio | 209.3k $5.4m | Added +197.2k |
| Soleus Capital Management, L.P. 0.51% of their portfolio | 176.0k $4.6m | Reduced -66.0k |
| Highlander Partners, L.P. 3.58% of their portfolio | 123.0k $3.2m | Unchanged |
| Rafferty Asset Management, LLC 0.02% of their portfolio | 115.9k $3.0m | Added +29.7k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 112.2k $2.9m | Added +52.3k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 111.4k $2.9m | Added +48.0k |
| UBS Group AG 0.00% of their portfolio | 110.6k $2.9m | Added +70.1k |
| SILVERARC CAPITAL MANAGEMENT, LLC 0.93% of their portfolio | 106.4k $2.8m | Added +436 |
| MORGAN STANLEY 0.00% of their portfolio | 104.5k $2.7m | Added +60.3k |
| TWO SIGMA INVESTMENTS, LP 0.01% of their portfolio | 103.1k $2.7m | New |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 99.7k $2.6m | Added +87.8k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 84.7k $2.2m | Reduced -21.1k |
| Nuveen Asset Management, LLC 0.00% of their portfolio | 75.6k $2.0m | Added +3.9k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 72.3k $1.9m | Added +19.5k |
| Simplify Asset Management Inc. 0.33% of their portfolio | 70.0k $1.8m | Unchanged |
| RAYMOND JAMES & ASSOCIATES 0.00% of their portfolio | 67.6k $1.7m | Added +39.0k |
| INTERNATIONAL BIOTECHNOLOGY TRUST PLC 0.53% of their portfolio | 67.5k $1.7m | Unchanged |
| Palo Alto Investors LP 0.14% of their portfolio | 64.7k $1.7m | Unchanged |
| TWO SIGMA ADVISERS, LP 0.00% of their portfolio | 62.6k $1.6m | Added +32.3k |
| Parkman Healthcare Partners LLC 0.28% of their portfolio | 62.4k $1.6m | Added +292 |
| Knights of Columbus Asset Advisors LLC 0.13% of their portfolio | 57.1k $1.5m | Added +49.8k |
| RICE HALL JAMES & ASSOCIATES, LLC 0.08% of their portfolio | 54.5k $1.4m | Added +2.2k |
| Swiss National Bank 0.00% of their portfolio | 53.7k $1.4m | Added +9.9k |
| Allspring Global Investments Holdings, LLC 0.00% of their portfolio | 42.1k $1.1m | Added +5.7k |
| LOS ANGELES CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 42.0k $1.1m | New |
| CITIGROUP INC 0.00% of their portfolio | 40.8k $1.1m | Reduced -28.6k |
| Qube Research & Technologies Ltd 0.00% of their portfolio | 39.9k $1.0m | New |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 38.5k $995.1k | Added +24.3k |
| Raymond James Financial Services Advisors, Inc. 0.00% of their portfolio | 38.0k $983.8k | Reduced -1.4k |
| Schonfeld Strategic Advisors LLC 0.01% of their portfolio | 37.8k $977.0k | Reduced -57.7k |
| Connor, Clark & Lunn Investment Management Ltd. 0.00% of their portfolio | 37.7k $976.3k | New |
| Squarepoint Ops LLC 0.01% of their portfolio | 37.3k $963.9k | New |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 35.8k $926.2k | Added +11.7k |
| Secure Asset Management, LLC 0.28% of their portfolio | 35.6k $919.8k | Reduced -3.5k |
| Invesco Ltd. 0.00% of their portfolio | 35.4k $915.6k | Reduced -5.2k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 34.3k $886.7k | Added +10.2k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 30.8k $795.8k | Added +12.8k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 30.6k $791.6k | Added +5.9k |
| Affinity Asset Advisors, LLC 0.31% of their portfolio | 30.0k $776.1k | Reduced -65.0k |
| ADAMS STREET PARTNERS LLC 0.20% of their portfolio | 29.8k $772.2k | New |
| CREDIT SUISSE AG/ 0.00% of their portfolio | 29.0k $750.6k | Added +12.5k |
| CenterBook Partners LP 0.09% of their portfolio | 28.1k $727.5k | Reduced -26.2k |
| Lion Point Capital, LP 0.52% of their portfolio | 27.0k $698.5k | Reduced -70.0k |
| Legato Capital Management LLC 0.09% of their portfolio | 26.0k $672.5k | New |
| ALGERT GLOBAL LLC 0.03% of their portfolio | 25.9k $671.1k | New |
| PATHWAY CAPITAL MANAGEMENT, LP 1.15% of their portfolio | 24.8k $641.2k | New |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) 0.01% of their portfolio | 24.0k $620.9k | Not comparable |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 22.8k $548.8k | Unchanged |
| PROFUND ADVISORS LLC 0.03% of their portfolio | 21.1k $546.3k | Added +5.1k |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 20.9k $540.7k | Added +1.4k |
| Legal & General Group Plc 0.00% of their portfolio | 20.8k $538.4k | Added +13.0k |
| Clearbridge Investments, LLC 0.00% of their portfolio | 20.6k $532.0k | Reduced -30.4k |
| Ascentis Independent Advisors 0.13% of their portfolio | 18.0k $465.1k | Unchanged |
| Janney Montgomery Scott LLC 0.00% of their portfolio | 18.0k $465.0k | Added +100 |
| Utah Retirement Systems 0.01% of their portfolio | 17.9k $463.3k | New |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 17.6k $454.1k | Added +3.3k |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 17.1k $441.9k | Reduced -1.9k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 16.9k $436.3k | Reduced -51.9k |
| SG Americas Securities, LLC 0.00% of their portfolio | 16.7k $431.0k | Added +7.9k |
| Virtu Financial LLC 0.03% of their portfolio | 15.3k $397.0k | New |
| Campbell & CO Investment Adviser LLC 0.07% of their portfolio | 15.0k $387.4k | New |
| MetLife Investment Management, LLC 0.00% of their portfolio | 14.1k $365.4k | Added +5.2k |
| Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio | 14.0k $358.1k | Added +654 |
| Hennion & Walsh Asset Management, Inc. 0.02% of their portfolio | 14.0k $362.0k | New |
| AMERICAN INTERNATIONAL GROUP, INC. 0.00% of their portfolio | 12.9k $332.9k | Added +4.0k |
| Centiva Capital, LP 0.02% of their portfolio | 12.5k $324.3k | New |
| Jump Financial, LLC 0.01% of their portfolio | 12.4k $319.8k | New |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 12.2k $316.3k | Reduced -2.3k |