LIGAND PHARMACEUTICALS INC LGND
COM NEW · Common Stock · CUSIP 53220K504
Biopharmaceutical company based out of La Jolla, California
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersSan Diego, CA
- Founded1987
- Websiteligand.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($28.5m this quarter). Holder counts are more reliable. Shares outstanding: 19.9m as of 2026-08-04, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $315.85. Options: 7 managers hold calls ($131.6m notional), 7 hold puts ($13.5m).
Trends to Q2 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 204 |
| Q4 2022 | 197 |
| Q1 2023 | 213 |
| Q2 2023 | 204 |
| Q3 2023 | 197 |
| Q4 2023 | 211 |
| Q1 2024 | 222 |
| Q2 2024 | 235 |
| Q3 2024 | 243 |
| Q4 2024 | 259 |
| Q1 2025 | 263 |
| Q2 2025 | 272 |
| Q3 2025 | 314 |
| Q4 2025 | 351 |
| Q1 2026 | 359 |
| Q2 2026 | 415 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2024 | 131 | 81 |
| Q4 2024 | 139 | 84 |
| Q1 2025 | 132 | 112 |
| Q2 2025 | 140 | 111 |
| Q3 2025 | 161 | 118 |
| Q4 2025 | 168 | 146 |
| Q1 2026 | 183 | 158 |
| Q2 2026 | 242 | 147 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2025 | $3.5m | $2.0m | 0.58 |
| Q4 2025 | $6.7m | $1.8m | 0.26 |
| Q1 2026 | $8.5m | $6.9m | 0.82 |
| Q2 2026 | $131.6m | $13.5m | 0.10 |
Biggest buyers
| Invesco Ltd. | Added | +378.0k |
| NEUBERGER BERMAN GROUP LLC | Added | +246.9k |
| FRANKLIN RESOURCES INC | Added | +178.9k |
| FMR LLC | Added | +166.7k |
| CONGRESS ASSET MANAGEMENT CO | Added | +155.3k |
| BlackRock, Inc. | Added | +139.1k |
| VOYA INVESTMENT MANAGEMENT LLC | Added | +123.7k |
| Granahan Investment Management, LLC | Added | +123.1k |
| NEXT CENTURY GROWTH INVESTORS LLC | Added | +102.7k |
| GW&K Investment Management, LLC | Added | +97.4k |
Biggest sellers
| BANK OF MONTREAL /CAN/ | Reduced | -63.9k |
| LOOMIS SAYLES & CO L P | Reduced | -61.4k |
| Fiera Capital Corp | Reduced | -58.0k |
| GOLDMAN SACHS GROUP INC | Reduced | -57.9k |
| Pictet Asset Management Holding SA | Reduced | -57.7k |
| Clark Capital Management Group, Inc. | Reduced | -57.3k |
| DEUTSCHE BANK AG\ | Reduced | -56.5k |
| NOMURA HOLDINGS INC | Reduced | -52.4k |
| VICTORY CAPITAL MANAGEMENT INC | Reduced | -49.5k |
| Qube Research & Technologies Ltd | Sold out | -47.7k |
Biggest calls
| BNP PARIBAS FINANCIAL MARKETS | New | $117.0m3.7k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $5.0m15.7k shares |
| JANE STREET GROUP, LLC | Added | $3.2m10.1k shares |
| CITADEL ADVISORS LLC | Reduced | $3.2m10.0k shares |
| D. E. Shaw & Co., Inc. | Added | $2.6m8.2k shares |
| Walleye Capital LLC | New | $537.4k1.7k shares |
| SIMPLEX TRADING, LLC | Added | $189.7k600 shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $10.3m32.6k shares |
| JANE STREET GROUP, LLC | Added | $1.3m4.0k shares |
| D. E. Shaw & Co., Inc. | Added | $885.1k2.8k shares |
| CITADEL ADVISORS LLC | New | $537.4k1.7k shares |
| Point72 Asset Management, L.P. | New | $252.9k800 shares |
| SIMPLEX TRADING, LLC | Added | $126.4k400 shares |
| Walleye Capital LLC | New | $94.8k300 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| BlackRock, Inc. 13G · institution -1.1 pts · filed 2025-10-17 | 14.5% |
| Invesco Ltd. 13G · institution new · filed 2026-08-13 | 6.1% |
| VANGUARD PORTFOLIO MANAGEMENT LLC 13G · institution new · filed 2026-05-01 | 5.6% |
| JANUS HENDERSON GROUP PLC 13G · institution -0.2 pts · filed 2025-11-14 | 5.3% |
| VANGUARD CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-05-01 | 5.0% |
Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-27; now reported by VANGUARD PORTFOLIO MANAGEMENT LLC)
Insider purchases and sales since 1 Apr 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2024 | 0 | — | 2 | $542.3k | — |
| Q1 2025 | 0 | — | 1 | $575.1k | — |
| Q2 2025 | 2 | $1.2m | 1 | $218.3k | — |
| Q3 2025 | 0 | — | 2 | $2.0m | $254.1k |
| Q4 2025 | 0 | — | 4 | $2.8m | $264.5k |
| Q1 2026 | 0 | — | 5 | $5.8m | $4.8m |
| Q2 2026 | 0 | — | 6 | $8.6m | $4.0m |
| Q3 2026 | 0 | — | 4 | $16.1m | $13.7m |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2026-09-10 | Zimmermann Martine Director | Sold | $342.0k1.2k shares |
| 2026-09-03 | Reardon Andrew CLO & Secretary | Sold plan | $1.4m5.0k shares |
| 2026-08-12 | Espinoza Octavio Chief Financial Officer | Sold plan | $9.2m31.6k shares |
| 2026-08-12 | Haas Jason Director | Sold | $2.1m7.1k shares |
| 2026-08-03 | Reardon Andrew CLO & Secretary | Sold plan | $1.4m5.0k shares |
| 2026-07-01 | Reardon Andrew CLO & Secretary | Sold plan | $1.6m5.0k shares |
| 2026-06-16 | Sabba Stephen L Director | Sold | $544.8k2.1k shares |
| 2026-06-12 | Haas Jason Director | Sold | $1.7m6.5k shares |
| 2026-06-11 | Aryeh Jason Director | Sold | $1.1m4.5k shares |
| 2026-06-10 | LAMATTINA JOHN L Director | Sold | $1.2m4.6k shares |
| 2026-06-10 | Aryeh Jason Director | Sold | $125.0k500 shares |
| 2026-06-01 | Reardon Andrew CLO & Secretary | Sold plan | $1.1m5.0k shares |
| 2026-05-13 | KOZARICH JOHN W Director | Sold plan | $352.0k1.6k shares |
| 2026-05-12 | KOZARICH JOHN W Director | Sold plan | $102.8k459 shares |
| 2026-05-01 | Reardon Andrew CLO & Secretary | Sold plan | $1.2m5.0k shares |
| 2026-05-01 | KOZARICH JOHN W Director | Sold plan | $108.3k467 shares |
| 2026-04-01 | Reardon Andrew CLO & Secretary | Sold plan | $1.0m5.0k shares |
| 2026-04-01 | KOZARICH JOHN W Director | Sold plan | $94.4k467 shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2026
| Manager | Shares | Change |
|---|---|---|
| BlackRock, Inc. 0.01% of their portfolio | 3.1m $980.2m | Added +139.1k |
| Invesco Ltd. 0.03% of their portfolio | 1.2m $379.8m | Added +378.0k |
| VANGUARD PORTFOLIO MANAGEMENT LLC 0.02% of their portfolio | 1.1m $359.8m | Added +38.0k |
| Jupiter Topco LLC 0.13% of their portfolio | 1.0m $328.9m | First filing |
| VANGUARD CAPITAL MANAGEMENT LLC 0.01% of their portfolio | 871.0k $275.3m | Added +22.9k |
| STATE STREET CORP 0.01% of their portfolio | 826.5k $261.3m | Added +47.7k |
| FMR LLC 0.01% of their portfolio | 762.8k $241.1m | Added +166.7k |
| FRANKLIN RESOURCES INC 0.05% of their portfolio | 752.0k $237.7m | Added +178.9k |
| CONGRESS ASSET MANAGEMENT CO 1.28% of their portfolio | 659.9k $208.6m | Added +155.3k |
| GEODE CAPITAL MANAGEMENT, LLC 0.01% of their portfolio | 589.0k $186.2m | Added +30.1k |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. 0.27% of their portfolio | 568.4k $179.7m | Reduced -4.9k |
| Chicago Capital, LLC 4.21% of their portfolio | 553.4k $174.9m | Reduced -8.2k |
| Stephens Investment Management Group LLC 1.61% of their portfolio | 475.6k $150.3m | Reduced -19.1k |
| DIMENSIONAL FUND ADVISORS LP 0.02% of their portfolio | 429.3k $135.7m | Added +4.1k |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ 0.04% of their portfolio | 375.8k $118.8m | Reduced -35.8k |
| GOLDMAN SACHS GROUP INC 0.01% of their portfolio | 323.2k $102.2m | Reduced -57.9k |
| LOOMIS SAYLES & CO L P 0.12% of their portfolio | 291.8k $92.2m | Reduced -61.4k |
| RICE HALL JAMES & ASSOCIATES, LLC 4.15% of their portfolio | 270.1k $85.4m | Reduced -13.5k |
| Ranger Investment Management, L.P. 5.15% of their portfolio | 257.6k $81.4m | Reduced -10.3k |
| NORTHERN TRUST CORP 0.01% of their portfolio | 257.4k $81.4m | Added +3.2k |
| VICTORY CAPITAL MANAGEMENT INC 0.04% of their portfolio | 253.8k $80.2m | Reduced -49.5k |
| DEUTSCHE BANK AG\ 0.02% of their portfolio | 249.6k $78.9m | Reduced -56.5k |
| NEUBERGER BERMAN GROUP LLC 0.05% of their portfolio | 248.4k $78.5m | Added +246.9k |
| GW&K Investment Management, LLC 0.61% of their portfolio | 246.9k $78.0m | Added +97.4k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.01% of their portfolio | 210.4k $66.5m | Reduced -2.5k |
| MORGAN STANLEY 0.00% of their portfolio | 200.7k $63.4m | Added +33.5k |
| NEXT CENTURY GROWTH INVESTORS LLC 3.33% of their portfolio | 198.5k $62.8m | Added +102.7k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.01% of their portfolio | 193.2k $61.1m | Added +10.4k |
| Aberdeen Group plc 0.08% of their portfolio | 172.5k $54.5m | Added +82.4k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 170.3k $53.8m | Added +12.5k |
| ASHFORD CAPITAL MANAGEMENT INC 5.77% of their portfolio | 170.2k $53.8m | Reduced -37.3k |
| Private Capital Management, LLC 4.76% of their portfolio | 166.0k $52.5m | Reduced -35.4k |
| VILLERE ST DENIS J & CO LLC 5.87% of their portfolio | 155.5k $49.2m | Reduced -33.4k |
| Granahan Investment Management, LLC 1.66% of their portfolio | 147.2k $46.5m | Added +123.1k |
| VANGUARD FIDUCIARY TRUST CO 0.01% of their portfolio | 142.9k $45.2m | Added +15.0k |
| BESSEMER GROUP INC 0.06% of their portfolio | 141.4k $44.7m | Added +33.6k |
| NEW YORK STATE COMMON RETIREMENT FUND 0.05% of their portfolio | 137.3k $43.4m | Added +17.4k |
| Bank of New York Mellon Corp 0.01% of their portfolio | 131.1k $41.4m | Added +11.7k |
| Impax Asset Management Group plc 0.27% of their portfolio | 130.0k $41.1m | Reduced -22.4k |
| VOYA INVESTMENT MANAGEMENT LLC 0.03% of their portfolio | 127.1k $40.2m | Added +123.7k |
| UBS Group AG 0.01% of their portfolio | 124.7k $39.4m | Added +20.1k |
| Fisher Asset Management, LLC 0.01% of their portfolio | 121.4k $38.4m | Reduced -6.6k |
| Russell Investments Group, Ltd. 0.03% of their portfolio | 120.3k $38.0m | Reduced -847 |
| ROYAL BANK OF CANADA 0.01% of their portfolio | 119.1k $37.6m | Added +7.5k |
| Driehaus Capital Management LLC 0.22% of their portfolio | 118.5k $37.5m | Added +328 |
| Penn Capital Management Company, LLC 2.01% of their portfolio | 100.3k $31.7m | Added +4.9k |
| Legal & General Group Plc 0.01% of their portfolio | 98.7k $31.2m | Added +1.1k |
| PRINCIPAL FINANCIAL GROUP INC 0.02% of their portfolio | 98.0k $31.0m | Added +2.3k |
| BNP PARIBAS FINANCIAL MARKETS 0.02% of their portfolio | 94.1k $29.7m | Added +59.2k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 91.5k $28.9m | Added +67.6k |
| FIRST TRUST ADVISORS LP 0.02% of their portfolio | 90.9k $28.7m | Added +10.5k |
| OSAIC HOLDINGS, INC. 0.03% of their portfolio | 90.2k $28.5m | Added +32.1k |
| SEI INVESTMENTS CO 0.03% of their portfolio | 89.7k $28.3m | Added +14.5k |
| Pembroke Management, LTD 1.80% of their portfolio | 80.6k $25.5m | New |
| Fiera Capital Corp 0.09% of their portfolio | 77.3k $24.4m | Reduced -58.0k |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 76.2k $24.1m | Reduced -1.1k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 73.1k $23.2m | Reduced -13.2k |
| Public Sector Pension Investment Board 0.06% of their portfolio | 68.9k $21.8m | Reduced -1.5k |
| CITIGROUP INC 0.01% of their portfolio | 66.6k $21.1m | Added +45.0k |
| CASTLEARK MANAGEMENT LLC 0.53% of their portfolio | 62.0k $19.6m | Added +13.3k |
| NOMURA HOLDINGS INC 0.08% of their portfolio | 61.9k $19.6m | Reduced -52.4k |
| Dana Investment Advisors, Inc. 0.47% of their portfolio | 57.5k $18.2m | Reduced -11.7k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 57.3k $18.1m | Reduced -27.6k |
| D. E. Shaw & Co., Inc. 0.01% of their portfolio | 56.5k $17.9m | Reduced -21.9k |
| PRUDENTIAL FINANCIAL INC 0.02% of their portfolio | 54.6k $17.3m | Reduced -9.5k |
| Granite Investment Partners, LLC 0.88% of their portfolio | 54.1k $17.1m | Reduced -27 |
| Allspring Global Investments Holdings, LLC 0.02% of their portfolio | 51.9k $16.2m | Reduced -704 |
| RHUMBLINE ADVISERS 0.01% of their portfolio | 50.1k $15.8m | Reduced -6.7k |
| NORDEA INVESTMENT MANAGEMENT AB 0.01% of their portfolio | 49.9k $15.9m | Reduced -993 |
| Emerald Investment Advisers, LLC 0.99% of their portfolio | 46.9k $14.8m | Added +2.7k |
| Nuveen, LLC 0.00% of their portfolio | 46.6k $14.7m | Added +4.0k |
| Context Capital Management, LLC 0.29% of their portfolio | 46.0k $14.5m | New |
| SUSQUEHANNA ADVISORS GROUP, INC. 0.39% of their portfolio | 44.6k $14.1m | New |
| WCM INVESTMENT MANAGEMENT, LLC 0.03% of their portfolio | 44.6k $14.0m | Reduced -88 |
| KORNITZER CAPITAL MANAGEMENT INC /KS 0.29% of their portfolio | 44.5k $14.1m | Reduced -15.8k |
| ESSEX INVESTMENT MANAGEMENT CO LLC 1.80% of their portfolio | 43.6k $13.8m | Reduced -14.9k |
| ENVESTNET ASSET MANAGEMENT INC 0.00% of their portfolio | 40.4k $12.8m | Added +5.8k |
| Swiss National Bank 0.01% of their portfolio | 39.0k $12.3m | Added +100 |
| ARISTEIA CAPITAL, L.L.C. 0.19% of their portfolio | 37.2k $11.8m | New |
| STIFEL FINANCIAL CORP 0.01% of their portfolio | 36.8k $11.6m | Added +3.8k |
| CAPTRUST FINANCIAL ADVISORS 0.02% of their portfolio | 34.6k $10.9m | Added +4.7k |
| Uniplan Investment Counsel, Inc. 1.02% of their portfolio | 34.2k $10.8m | Reduced -5.9k |
| Universal- Beteiligungs- und Servicegesellschaft mbH 0.02% of their portfolio | 33.9k $10.7m | Added +8.6k |
| KENNEDY CAPITAL MANAGEMENT LLC 0.19% of their portfolio | 33.4k $10.5m | New |
| Clark Capital Management Group, Inc. 0.06% of their portfolio | 32.9k $10.4m | Reduced -57.3k |
| Moody Aldrich Partners LLC 1.60% of their portfolio | 28.2k $8.9m | Added +13.5k |
| Linden Advisors LP 0.04% of their portfolio | 27.4k $8.7m | New |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 27.1k $5.4m | Added +2.8k |
| Hodges Capital Management Inc. 0.49% of their portfolio | 23.4k $7.4m | New |
| Squarepoint Ops LLC 0.01% of their portfolio | 22.8k $7.2m | Added +16.4k |
| Calamos Advisors LLC 0.03% of their portfolio | 22.4k $7.1m | Added +1.6k |
| BANK OF MONTREAL /CAN/ 0.00% of their portfolio | 22.3k $7.1m | Reduced -63.9k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.01% of their portfolio | 22.1k $7.0m | Reduced -1.7k |
| NEW YORK STATE TEACHERS RETIREMENT SYSTEM 0.01% of their portfolio | 20.9k $6.6m | Reduced -3.6k |
| ISTHMUS PARTNERS, LLC 0.64% of their portfolio | 20.9k $6.6m | Reduced -3.1k |
| Moran Wealth Management, LLC 0.17% of their portfolio | 19.8k $6.3m | Added +484 |
| LAZARD ASSET MANAGEMENT LLC 0.01% of their portfolio | 19.7k $6.2m | New |
| TD Waterhouse Canada Inc. 0.02% of their portfolio | 19.6k $6.1m | New |
| Informed Momentum Co LLC 0.55% of their portfolio | 19.5k $6.2m | New |
| PALISADE CAPITAL MANAGEMENT, LP 0.26% of their portfolio | 19.1k $6.0m | Reduced -1.5k |