Vault-13

KALVISTA PHARMACEUTICALS INC KALV

COM · Common Stock · CUSIP 483497103

129 institutional holders -2 vs Q4 2024
54,929,32254.9m shares reported held*
$640.5mreported value*
22 new 45 added 34 reduced 23 sold out net sold ≈ $3.2m (-279.6k shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($19.6k this quarter). Holder counts are more reliable. Implied quarter-end price ≈ $11.66. Options: 13 managers hold calls ($15.8m notional), 2 hold puts ($69.2k).

Trends to Q1 2025

Institutional holders

Managers reporting a position, each quarter

050100150Q3 22: 94Q4 22: 91Q1 23: 90Q2 23: 96Q3 23: 102Q4 23: 94Q1 24: 130Q2 24: 120Q3 24: 123Q4 24: 131Q1 25: 129129Q3 22Q1 23Q3 23Q1 24Q3 24Q1 25
Numbers
QuarterHolders
Q3 202294
Q4 202291
Q1 202390
Q2 202396
Q3 2023102
Q4 202394
Q1 2024130
Q2 2024120
Q3 2024123
Q4 2024131
Q1 2025129

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
1000100Q2 23: 53 bought or addedQ2 23: 36 cut or sold outQ3 23: 52 bought or addedQ3 23: 38 cut or sold outQ3 23Q4 23: 54 bought or addedQ4 23: 44 cut or sold outQ1 24: 79 bought or addedQ1 24: 45 cut or sold outQ1 24Q2 24: 61 bought or addedQ2 24: 61 cut or sold outQ3 24: 65 bought or addedQ3 24: 44 cut or sold outQ3 24Q4 24: 69 bought or addedQ4 24: 48 cut or sold outQ1 25: 67 bought or addedQ1 25: 57 cut or sold outQ1 25
Numbers
QuarterBought or addedCut or sold out
Q2 20235336
Q3 20235238
Q4 20235444
Q1 20247945
Q2 20246161
Q3 20246544
Q4 20246948
Q1 20256757

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$5m$10m$15m$20mQ2 24 calls: $372.9kQ2 24 puts: $441.0kQ2 24P/C 1.18Q3 24 calls: $5.8mQ3 24 puts: $1.4mQ3 24P/C 0.23Q4 24 calls: $115.2kQ4 24 puts: $1.8mQ4 24P/C 15.64Q1 25 calls: $15.8mQ1 25 puts: $69.2kQ1 25P/C 0.00
Numbers
QuarterCallsPutsP/C
Q2 2024$372.9k$441.0k1.18
Q3 2024$5.8m$1.4m0.23
Q4 2024$115.2k$1.8m15.64
Q1 2025$15.8m$69.2k0.00

Biggest buyers

SILVERARC CAPITAL MANAGEMENT, LLC Added +1,086,811+1.1m
Parkman Healthcare Partners LLC New +753,752+753.8k
Schonfeld Strategic Advisors LLC New +581,746+581.7k
Venrock Adviser, LLC Added +454,254+454.3k
JPMORGAN CHASE & CO Added +381,244+381.2k
Woodline Partners LP Added +329,068+329.1k
BlackRock, Inc. Added +287,739+287.7k
MILLENNIUM MANAGEMENT LLC New +198,205+198.2k
BANK OF AMERICA CORP /DE/ Added +198,197+198.2k
DIADEMA PARTNERS LP New +135,509+135.5k

Biggest sellers

Boxer Capital Management, LLC Sold out -1,590,000-1.6m
GREAT POINT PARTNERS LLC Reduced -772,636-772.6k
STEMPOINT CAPITAL LP Reduced -605,966-606.0k
READYSTATE ASSET MANAGEMENT LP Sold out -315,700-315.7k
Saturn V Capital Management LP Reduced -301,429-301.4k
STATE STREET CORP Reduced -297,220-297.2k
Capital World Investors Reduced -196,477-196.5k
CITIGROUP INC Reduced -179,069-179.1k
CITADEL ADVISORS LLC Sold out -136,493-136.5k
Qube Research & Technologies Ltd Sold out -126,132-126.1k

Biggest calls

Caption Management, LLC New $5.2m450.0k shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP New $3.9m337.4k shares
Jefferies Financial Group Inc. New $1.8m158.3k shares
SIMPLEX TRADING, LLC Added $1.4m119.1k shares
DIADEMA PARTNERS LP New $1.2m103.3k shares
GROUP ONE TRADING LLC Added $699.3k60.6k shares
JANE STREET GROUP, LLC New $577.0k50.0k shares
CITADEL ADVISORS LLC Added $489.3k42.4k shares
Hudson Bay Capital Management LP New $461.6k40.0k shares
Persistent Asset Partners Ltd New $32.5k241 shares

Biggest puts

CITADEL ADVISORS LLC Reduced $69.2k6.0k shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
Capital World Investors 13G · institution filed 2025-05-13 6.4% 3.2m 2025-05-13
SILVERARC CAPITAL MANAGEMENT, LLC 13G · institution new · filed 2026-05-13 5.6% new 2.9m 2026-05-13

Fell to 5% or below in the last year: TANG CAPITAL MANAGEMENT LLC (0.0%, 2026-08-14), GLAZER CAPITAL, LLC (4.8%, 2026-06-10), Frazier Life Sciences Public Fund, L.P. (2.3%, 2026-05-21), Point72 Asset Management, L.P. (4.2%, 2026-05-15), MILLENNIUM MANAGEMENT LLC (3.7%, 2026-05-01), Vestal Point Capital, LP (1.5%, 2025-11-14)

Holders, Q1 2025

#ManagerLocationShares Value% of their portfolioChangeShares change
1 Venrock Adviser, LLC 6.58% of their portfolio NEW YORK, NY 6,703,9856.7m $77.4m $77.4m 6.58% Added +454.3k +454,254
2 TANG CAPITAL MANAGEMENT LLC 3.15% of their portfolio SAN DIEGO, CA 4,941,7984.9m $57.0m $57.0m 3.15% Added +48.0k +47,951
3 MONTANOVA CAPITAL, LLC 2.29% of their portfolio New York, NY 4,913,0124.9m $56.7m $56.7m 2.29% Unchanged
4 Frazier Life Sciences Management, L.P. 2.58% of their portfolio PALO ALTO, CA 4,887,8674.9m $56.4m $56.4m 2.58% Unchanged
5 Vestal Point Capital, LP 3.92% of their portfolio NEW YORK, NY 4,751,2924.8m $54.8m $54.8m 3.92% Reduced -18.7k -18,708
6 Capital World Investors 0.01% of their portfolio LOS ANGELES, CA 3,177,5873.2m $36.7m $36.7m 0.01% Reduced -196.5k -196,477
7 BlackRock, Inc. 0.00% of their portfolio New York, NY 3,151,7353.2m $36.4m $36.4m 0.00% Added +287.7k +287,739
8 VANGUARD GROUP INC 0.00% of their portfolio Valley Forge, PA 2,298,5982.3m $26.5m $26.5m 0.00% Added +43.4k +43,355
9 SILVERARC CAPITAL MANAGEMENT, LLC 4.10% of their portfolio BOSTON, MA 1,698,9841.7m $19.6m $19.6m 4.10% Added +1.1m +1,086,811
10 Woodline Partners LP 0.12% of their portfolio San Francisco, CA 1,617,4691.6m $18.7m $18.7m 0.12% Added +329.1k +329,068
11 Octagon Capital Advisors LP 3.11% of their portfolio NEW YORK, NY 1,370,0001.4m $15.8m $15.8m 3.11% Unchanged
12 STATE STREET CORP 0.00% of their portfolio BOSTON, MA 1,093,6431.1m $12.6m $12.6m 0.00% Reduced -297.2k -297,220
13 GREAT POINT PARTNERS LLC 6.36% of their portfolio Greenwich, CT 1,014,3671.0m $11.7m $11.7m 6.36% Reduced -772.6k -772,636
14 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 915,241915.2k $10.6m $10.6m 0.00% Added +92.9k +92,889
15 EMERALD ADVISERS, LLC 0.47% of their portfolio LEOLA, PA 898,190898.2k $10.4m $10.4m 0.47% Added +62.1k +62,140
16 SCHRODER INVESTMENT MANAGEMENT GROUP 0.01% of their portfolio London, X0 868,011868.0k $10.4m $10.4m 0.01% Added +62.6k +62,566
17 Parkman Healthcare Partners LLC 1.03% of their portfolio STAMFORD, CT 753,752753.8k $8.7m $8.7m 1.03% New
18 DAFNA Capital Management LLC 2.46% of their portfolio LOS ANGELES, CA 752,359752.4k $8.7m $8.7m 2.46% Reduced -59.3k -59,319
19 DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio AUSTIN, TX 645,993646.0k $7.5m $7.5m 0.00% Reduced -50.0k -50,044
20 EMERALD MUTUAL FUND ADVISERS TRUST 0.50% of their portfolio LEOLA, PA 608,213608.2k $7.0m $7.0m 0.50% Added +58.5k +58,525
21 Schonfeld Strategic Advisors LLC 0.05% of their portfolio NEW YORK, NY 581,746581.7k $6.7m $6.7m 0.05% New
22 UBS Group AG 0.00% of their portfolio ZURICH, V8 507,703507.7k $5.9m $5.9m 0.00% Added +133.1k +133,072
23 Allostery Investments LP 7.63% of their portfolio Stamford, CT 458,302458.3k $5.3m $5.3m 7.63% Reduced -20.8k -20,798
24 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 402,504402.5k $4.6m $4.6m 0.00% Added +381.2k +381,244
25 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 387,562387.6k $4.5m $4.5m 0.00% Added +21.4k +21,392
26 STEMPOINT CAPITAL LP 1.43% of their portfolio NEW YORK, NY 386,837386.8k $4.5m $4.5m 1.43% Reduced -606.0k -605,966
27 Jefferies Financial Group Inc. 0.07% of their portfolio NEW YORK, NY 375,000375.0k $4.3m $4.3m 0.07% Unchanged
28 GOLDMAN SACHS GROUP INC 0.00% of their portfolio NEW YORK, NY 339,936339.9k $3.9m $3.9m 0.00% Added +12.3k +12,263
29 BANK OF AMERICA CORP /DE/ 0.00% of their portfolio CHARLOTTE, NC 308,247308.2k $3.6m $3.6m 0.00% Added +198.2k +198,197
30 Rosalind Advisors, Inc. 1.71% of their portfolio TORONTO, A6 303,864303.9k $3.5m $3.5m 1.71% Unchanged
31 ADAGE CAPITAL PARTNERS GP, L.L.C. 0.01% of their portfolio Boston, MA 276,000276.0k $3.2m $3.2m 0.01% Reduced -24.0k -24,000
32 Saturn V Capital Management LP 1.49% of their portfolio AUSTIN, TX 255,060255.1k $2.9m $2.9m 1.49% Reduced -301.4k -301,429
33 Walleye Capital LLC 0.03% of their portfolio NEW YORK, NY 249,161249.2k $2.9m $2.9m 0.03% Reduced -18.6k -18,582
34 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 223,789223.8k $2.6m $2.6m 0.00% Reduced -65.7k -65,726
35 MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio NEW YORK, NY 198,205198.2k $2.3m $2.3m 0.00% New
36 OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) 0.05% of their portfolio CHICAGO, IL 169,692169.7k $2.0m $2.0m 0.05% Reduced -3.0k -3,001
37 Nan Fung Group Holdings Ltd 1.45% of their portfolio KAI TAK, K3 154,522154.5k $1.8m $1.8m 1.45% Unchanged
38 CITIGROUP INC 0.00% of their portfolio NEW YORK, NY 148,227148.2k $1.7m $1.7m 0.00% Reduced -179.1k -179,069
39 DIADEMA PARTNERS LP 1.25% of their portfolio MORRISTOWN, NJ 135,509135.5k $1.6m $1.6m 1.25% New
40 WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio Boston, MA 126,268126.3k $1.5m $1.5m 0.00% Added +3.4k +3,405
41 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio SAN FRANCISCO, CA 113,124113.1k $1.3m $1.3m 0.00% Added +12.8k +12,776
42 Hennion & Walsh Asset Management, Inc. 0.06% of their portfolio Parsippany, NJ 111,106111.1k $1.3m $1.3m 0.06% Added +36.3k +36,279
43 Bank of New York Mellon Corp 0.00% of their portfolio NEW YORK, NY 103,530103.5k $1.2m $1.2m 0.00% Added +5.0k +4,983
44 FMR LLC 0.00% of their portfolio BOSTON, MA 82,89682.9k $956.6k $956.6k 0.00% Added +891 +891
45 MARSHALL WACE, LLP 0.00% of their portfolio LONDON, X0 80,96581.0k $934.3k $934.3k 0.00% Reduced -37.0k -37,013
46 PANAGORA ASSET MANAGEMENT INC 0.00% of their portfolio BOSTON, MA 71,89671.9k $829.7k $829.7k 0.00% Unchanged
47 Birchview Capital, LP 0.67% of their portfolio BURLINGTON, VT 67,00267.0k $773.2k $773.2k 0.67% Reduced -67.0k -66,998
48 STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio MADISON, WI 61,04361.0k $704.4k $704.4k 0.00% Reduced -4.7k -4,705
49 AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio Greenwich, CT 55,97556.0k $646.0k $646.0k 0.00% New
50 BARCLAYS PLC 0.00% of their portfolio LONDON, X0 55,22755.2k $637.3k $637.3k 0.00% Reduced -12.8k -12,835
51 Russell Investments Group, Ltd. 0.00% of their portfolio Seattle, WA 53,02853.0k $611.9k $611.9k 0.00% Reduced -80.5k -80,544
52 RHUMBLINE ADVISERS 0.00% of their portfolio BOSTON, MA 52,91852.9k $610.7k $610.7k 0.00% Added +1.8k +1,762
53 SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio BALA CYNWYD, PA 52,16852.2k $602.0k $602.0k 0.00% Added +23.0k +22,990
54 F/m Investments LLC 0.02% of their portfolio WASHINGTON, DC 50,09750.1k $578.1k $578.1k 0.02% New
55 SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC 0.01% of their portfolio BALA CYNWYD, PA 43,14343.1k $497.9k $497.9k 0.01% Reduced -37.2k -37,176
56 Skandinaviska Enskilda Banken AB (publ) 0.00% of their portfolio STOCKHOLM, V7 40,86340.9k $471.1k $471.1k 0.00% Unchanged
57 AMERIPRISE FINANCIAL INC 0.00% of their portfolio MINNEAPOLIS, MN 40,07240.1k $462.4k $462.4k 0.00% Reduced -13.3k -13,310
58 ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio NASHVILLE, TN 40,02040.0k $461.8k $461.8k 0.00% Unchanged
59 Invesco Ltd. 0.00% of their portfolio ATLANTA, GA 39,80439.8k $459.3k $459.3k 0.00% Added +24.2k +24,164
60 Nuveen, LLC 0.00% of their portfolio CHARLOTTE, NC 37,32137.3k $4.9m $4.9m 0.00% First filing
61 ADAR1 Capital Management, LLC 0.08% of their portfolio AUSTIN, TX 35,74335.7k $412.5k $412.5k 0.08% Reduced -100 -100
62 Persistent Asset Partners Ltd 0.35% of their portfolio HONG KONG, K3 34,09834.1k $393.5k $393.5k 0.35% Reduced -7.9k -7,854
63 HighVista Strategies LLC 0.15% of their portfolio BOSTON, MA 33,30533.3k $384.3k $384.3k 0.15% Unchanged
64 EVOKE WEALTH, LLC 0.01% of their portfolio Los Angeles, CA 32,44632.4k $374.4k $374.4k 0.01% Added +83 +83
65 DEUTSCHE BANK AG\ 0.00% of their portfolio FRANKFURT AM MAIN, 2M 32,12632.1k $370.7k $370.7k 0.00% Reduced -3.7k -3,715
66 Creative Planning 0.00% of their portfolio OVERLAND PARK, KS 27,80727.8k $320.9k $320.9k 0.00% Added +27.7k +27,694
67 Rafferty Asset Management, LLC 0.00% of their portfolio New York, NY 26,26926.3k $303.1k $303.1k 0.00% Reduced -28.2k -28,197
68 Engineers Gate Manager LP 0.01% of their portfolio NEW YORK, NY 25,84225.8k $298.2k $298.2k 0.01% New
69 D. E. Shaw & Co., Inc. 0.00% of their portfolio New York, NY 25,72025.7k $296.8k $296.8k 0.00% Reduced -47.6k -47,566
70 MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio CAUSEWAY BAY, K3 24,32524.3k $281.2k $281.2k 0.00% Added +2.9k +2,939
71 PDT Partners, LLC 0.02% of their portfolio New York, NY 23,65423.7k $273.0k $273.0k 0.02% Reduced -11.5k -11,547
72 WELLS FARGO & COMPANY/MN 0.00% of their portfolio SAN FRANCISCO, CA 22,86222.9k $263.8k $263.8k 0.00% Added +2.7k +2,697
73 MetLife Investment Management, LLC 0.00% of their portfolio Whippany, NJ 21,68821.7k $250.3k $250.3k 0.00% Added +2.5k +2,536
74 Stonepine Capital Management, LLC 0.24% of their portfolio Bend, OR 21,55021.6k $248.7k $248.7k 0.24% New
75 VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio ATLANTA, GA 20,47820.5k $236.3k $236.3k 0.00% Added +8.1k +8,088
76 Corebridge Financial, Inc. 0.00% of their portfolio HOUSTON, TX 19,09419.1k $220.3k $220.3k 0.00% Added +2.1k +2,149
77 Rathbones Group PLC 0.00% of their portfolio Liverpool, X0 19,02219.0k $219.5k $219.5k 0.00% Unchanged
78 INTECH INVESTMENT MANAGEMENT LLC 0.00% of their portfolio WEST PALM BEACH, FL 17,88817.9k $206.4k $206.4k 0.00% Added +684 +684
79 PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio BALTIMORE, MD 16,82316.8k $195.0k $195.0k 0.00% Added +3.0k +2,984
80 MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio Toronto, A6 13,80813.8k $159.3k $159.3k 0.00% Reduced -385 -385
81 IRONWOOD INVESTMENT MANAGEMENT LLC 0.07% of their portfolio BOSTON, MA 11,48811.5k $132.6k $132.6k 0.07% Unchanged
82 IEQ CAPITAL, LLC 0.00% of their portfolio Foster City, CA 10,91510.9k $126.0k $126.0k 0.00% New
83 ProShare Advisors LLC 0.00% of their portfolio BETHESDA, MD 10,66610.7k $123.1k $123.1k 0.00% Reduced -1.2k -1,240
84 Martin Worley Group 0.07% of their portfolio COTTONWOOD HEIGHTS, UT 10,16810.2k $117.3k $117.3k 0.07% Unchanged
85 Choate Investment Advisors 0.00% of their portfolio BOSTON, MA 10,00010.0k $115.4k $115.4k 0.00% Unchanged
86 NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio ALBANY, NY 9,96410.0k $115.0k $115.0k 0.00% Unchanged
87 China Universal Asset Management Co., Ltd. 0.01% of their portfolio SHANGHAI, F4 9,9129.9k $114.4k $114.4k 0.01% Reduced -417 -417
88 Legal & General Group Plc 0.00% of their portfolio London, X0 8,5408.5k $98.6k $98.6k 0.00% Added +396 +396
89 Quarry LP 0.02% of their portfolio NEW YORK, NY 8,4008.4k $96.9k $96.9k 0.02% New
90 Police & Firemen's Retirement System of New Jersey 0.00% of their portfolio TRENTON, NJ 7,6957.7k $88.8k $88.8k 0.00% Unchanged
91 CWM, LLC 0.00% of their portfolio OMAHA, NE 4,5854.6k $53.0k $53.0k 0.00% Added +4.5k +4,549
92 NISA INVESTMENT ADVISORS, LLC 0.00% of their portfolio ST. LOUIS, MO 4,5574.6k $52.6k $52.6k 0.00% Added +218 +218
93 EARNED WEALTH ADVISORS, LLC 0.40% of their portfolio WALNUT CREEK, CA 3,8453.8k $1.8m $1.8m 0.40% New
94 Ameritas Investment Partners, Inc. 0.00% of their portfolio LINCOLN, NE 3,7313.7k $43.1k $43.1k 0.00% Unchanged
95 BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio PARIS, I0 2,7492.7k $31.7k $31.7k 0.00% First filing
96 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio WEST SACRAMENTO, CA 2,5112.5k $29.0k $29.0k 0.00% Unchanged
97 Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio SEOUL, M5 1,6401.6k $19.6k $19.6k 0.00% Added +17 +17
98 1620 INVESTMENT ADVISORS, INC. 0.01% of their portfolio PLYMOUTH, MA 1,5901.6k $18.3k $18.3k 0.01% Unchanged
99 AMALGAMATED BANK 0.00% of their portfolio NEW YORK, NY 1,3431.3k $15.0k $15.0k 0.00% Added +278 +278
100 Parallel Advisors, LLC 0.00% of their portfolio SAN FRANCISCO, CA 1,2871.3k $14.9k $14.9k 0.00% Added +1.2k +1,184