PERSPECTIVE THERAPEUTICS INC CATX
COM NEW · Common Stock · CUSIP 46489V302
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersSeattle, WA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($151.7k this quarter). Holder counts are more reliable. Shares outstanding: 74.3m as of 2025-11-06, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $3.43. Options: 3 managers hold calls ($251.3k notional), 1 hold puts ($2.0k).
Trends to Q3 2025
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q2 2024 | 104 |
| Q3 2024 | 127 |
| Q4 2024 | 135 |
| Q1 2025 | 111 |
| Q2 2025 | 97 |
| Q3 2025 | 103 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2024 | 84 | 41 |
| Q4 2024 | 76 | 55 |
| Q1 2025 | 45 | 73 |
| Q2 2025 | 48 | 45 |
| Q3 2025 | 47 | 39 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q4 2024 | $331.3k | $526.7k | 1.59 |
| Q1 2025 | $91.9k | $22.3k | 0.24 |
| Q2 2025 | $382.5k | $2.0k | 0.01 |
| Q3 2025 | $251.3k | $2.0k | 0.01 |
Biggest buyers
| MORGAN STANLEY | Added | +1.1m |
| Avidity Partners Management LP | Added | +1.1m |
| BANK OF AMERICA CORP /DE/ | Added | +458.3k |
| Walleye Capital LLC | Added | +358.6k |
| Patient Square Capital LP | New | +349.3k |
| JANE STREET GROUP, LLC | New | +329.7k |
| UBS Group AG | Added | +268.4k |
| WELLINGTON MANAGEMENT GROUP LLP | New | +206.6k |
| SPHERA FUNDS MANAGEMENT LTD. | Added | +200.0k |
| Rothschild Wealth LLC | New | +164.7k |
Biggest sellers
| FMR LLC | Reduced | -1.1m |
| Nuveen, LLC | Reduced | -988.7k |
| Affinity Asset Advisors, LLC | Reduced | -750.0k |
| MARSHALL WACE, LLP | Sold out | -520.7k |
| Velan Capital Investment Management LP | Sold out | -500.0k |
| HighTower Advisors, LLC | Reduced | -164.7k |
| Schonfeld Strategic Advisors LLC | Sold out | -143.3k |
| BNP PARIBAS FINANCIAL MARKETS | Reduced | -138.9k |
| HighVista Strategies LLC | Sold out | -138.3k |
| TWO SIGMA ADVISERS, LP | Reduced | -89.6k |
Biggest calls
| GROUP ONE TRADING LLC | Reduced | $179.4k52.3k shares |
| CITADEL ADVISORS LLC | Reduced | $44.9k13.1k shares |
| SIMPLEX TRADING, LLC | Added | $27.0k7.9k shares |
Biggest puts
| SIMPLEX TRADING, LLC | Unchanged | $2.0k700 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| Commodore Capital LP 13G · passive investor new · filed 2026-02-09 | 9.9% |
| Lantheus Holdings, Inc. 13D · may seek influence -2.3 pts · filed 2026-09-23 | 7.7% |
| TCG Crossover GP II, LLC 13G · passive investor new · filed 2026-02-06 | 6.9% |
| BlackRock, Inc. 13G · institution +2.2 pts · filed 2026-07-29 | 6.8% |
| Qatar Investment Authority 13G · passive investor new · filed 2026-02-05 | 6.2% |
| MILLENNIUM MANAGEMENT LLC 13G · passive investor +0.2 pts · filed 2026-08-13 | 5.5% |
| STATE STREET CORP 13G · institution new · filed 2026-08-07 | 5.3% |
| Avidity Partners Management LP 13G · passive investor +1.1 pts · filed 2026-03-10 | 5.3% |
Fell to 5% or below in the last year: MORGAN STANLEY (2.6%, 2026-05-12), FMR LLC (0.4%, 2025-12-05)
Insider purchases and sales in Q3 2025
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2023 | 4 | — | 0 | — | — |
| Q1 2024 | 2 | — | 0 | — | — |
| Q2 2024 | 4 | $385.6k | 0 | — | — |
| Q3 2024 | 0 | — | 0 | — | — |
| Q4 2024 | 4 | $302.4k | 0 | — | — |
| Q1 2025 | 4 | $316.6k | 0 | — | — |
| Q2 2025 | 0 | — | 0 | — | — |
| Q3 2025 | 0 | — | 0 | — | — |
None reported in Q3 2025.
Holders, Q3 2025
| Manager | Shares | Change |
|---|---|---|
| FMR LLC 0.00% of their portfolio | 10.0m $34.3m | Reduced -1.1m |
| BlackRock, Inc. 0.00% of their portfolio | 4.4m $15.0m | Added +72.4k |
| VANGUARD GROUP INC 0.00% of their portfolio | 3.4m $11.8m | Added +163.5k |
| Avidity Partners Management LP 2.34% of their portfolio | 3.0m $10.3m | Added +1.1m |
| MORGAN STANLEY 0.00% of their portfolio | 2.8m $9.5m | Added +1.1m |
| MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio | 2.6m $8.8m | Reduced -32.5k |
| Nicholson Wealth Management Group, LLC 3.25% of their portfolio | 1.6m $5.6m | Added +4.0k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 1.4m $4.9m | Added +49.7k |
| Nuveen, LLC 0.00% of their portfolio | 1.3m $4.5m | Reduced -988.7k |
| STATE STREET CORP 0.00% of their portfolio | 1.1m $3.8m | Added +15.9k |
| Hills Bank & Trust Co 0.20% of their portfolio | 979.2k $3.4m | Reduced -5.0k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 872.7k $3.0m | Added +124.6k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 785.8k $2.7m | Added +458.3k |
| UBS Group AG 0.00% of their portfolio | 641.1k $2.2m | Added +268.4k |
| Walleye Capital LLC 0.02% of their portfolio | 546.0k $1.9m | Added +358.6k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 535.8k $1.8m | Reduced -1.7k |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 519.7k $1.8m | Reduced -82.1k |
| SPHERA FUNDS MANAGEMENT LTD. 0.42% of their portfolio | 510.3k $1.8m | Added +200.0k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 471.0k $1.6m | Reduced -8.2k |
| Rock Springs Capital Management LP 0.09% of their portfolio | 444.4k $1.5m | Unchanged |
| TWO SIGMA ADVISERS, LP 0.00% of their portfolio | 405.6k $1.4m | Reduced -89.6k |
| WealthPlan Investment Management, LLC 0.09% of their portfolio | 404.1k $1.4m | Added +3.0k |
| Patient Square Capital LP 0.32% of their portfolio | 349.3k $1.2m | New |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 329.7k $1.1m | New |
| Affinity Asset Advisors, LLC 0.10% of their portfolio | 300.0k $1.0m | Reduced -750.0k |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 206.6k $708.7k | New |
| FEDERATED HERMES, INC. 0.00% of their portfolio | 198.2k $679.8k | Added +3.1k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 197.7k $678.1k | Reduced -74.4k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 189.3k $649.5k | Added +9.7k |
| Rothschild Wealth LLC 0.12% of their portfolio | 164.7k $565.0k | New |
| Siligmueller & Norvid Wealth Advisors LLC 0.25% of their portfolio | 164.7k $565.0k | New |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 160.7k $551.1k | Added +116.2k |
| CITIGROUP INC 0.00% of their portfolio | 125.3k $429.8k | Added +28.8k |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 103.7k $355.8k | Reduced -138.9k |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.01% of their portfolio | 95.8k $328.6k | Reduced -15.0k |
| Taylor & Morgan Wealth Management, LLC 0.19% of their portfolio | 91.0k $312.1k | Reduced -3.0k |
| Mariner, LLC 0.00% of their portfolio | 86.1k $295.4k | Added +21.7k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 84.8k $290.9k | Added +1.6k |
| BARCLAYS PLC 0.00% of their portfolio | 83.9k $287.6k | Reduced -19.4k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 83.5k $286.3k | Unchanged |
| Trueblood Wealth Management, LLC 0.09% of their portfolio | 69.1k $236.9k | Unchanged |
| Qube Research & Technologies Ltd 0.00% of their portfolio | 69.0k $236.5k | Reduced -25.7k |
| XTX Topco Ltd 0.01% of their portfolio | 60.4k $207.2k | New |
| Cubist Systematic Strategies, LLC 0.00% of their portfolio | 56.7k $194.5k | Added +43.7k |
| CITIZENS FINANCIAL GROUP INC/RI 0.00% of their portfolio | 53.1k $182.1k | Unchanged |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 51.3k $176.0k | Reduced -65.0k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 51.1k $175.4k | Added +7.1k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 45.7k $156.7k | Added +7.5k |
| Graham Capital Management, L.P. 0.01% of their portfolio | 45.4k $155.6k | New |
| Point72 Asset Management, L.P. 0.00% of their portfolio | 44.2k $151.7k | Reduced -15.8k |
| Creative Planning 0.00% of their portfolio | 41.8k $143.3k | Reduced -196 |
| SYKON CAPITAL LLC 0.04% of their portfolio | 37.9k $130.1k | Unchanged |
| HighTower Advisors, LLC 0.00% of their portfolio | 36.9k $126.5k | Reduced -164.7k |
| SHERBROOKE PARK ADVISERS LLC 0.05% of their portfolio | 32.4k $111.2k | New |
| INTECH INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 29.9k $102.6k | Reduced -9.1k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 29.8k $103.0k | Added +978 |
| MetLife Investment Management, LLC 0.00% of their portfolio | 29.6k $101.4k | Reduced -2.0k |
| MERCER GLOBAL ADVISORS INC /ADV 0.00% of their portfolio | 29.3k $100.4k | Added +13.2k |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 28.0k $96.0k | Reduced -4.6k |
| WEALTH EFFECTS LLC 0.03% of their portfolio | 26.0k $89.2k | Added +2.0k |
| Koa Wealth Management, LLC 0.07% of their portfolio | 26.0k $89.1k | Unchanged |
| Invesco Ltd. 0.00% of their portfolio | 24.7k $84.8k | Added +2.5k |
| Quadrature Capital Ltd 0.00% of their portfolio | 24.2k $83.7k | New |
| MONETA GROUP INVESTMENT ADVISORS LLC 0.00% of their portfolio | 23.7k $81.3k | Unchanged |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 21.3k $73.0k | Reduced -276 |
| CIBC Asset Management Inc 0.00% of their portfolio | 20.9k $71.7k | Unchanged |
| Police & Firemen's Retirement System of New Jersey 0.00% of their portfolio | 20.8k $71.3k | Added +9.1k |
| Vontobel Holding Ltd. 0.00% of their portfolio | 20.0k $69.0k | Unchanged |
| Iowa State Bank 0.01% of their portfolio | 19.1k $65.4k | Unchanged |
| LOS ANGELES CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 17.6k $60.4k | Unchanged |
| Atom Investors LP 0.00% of their portfolio | 16.8k $57.7k | New |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 15.8k $54.0k | Reduced -4.6k |
| SG Americas Securities, LLC 0.00% of their portfolio | 13.5k $46.0k | New |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 10.7k $36.6k | Reduced -5.9k |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 10.3k $35.3k | Unchanged |
| AXQ CAPITAL, LP 0.01% of their portfolio | 10.3k $35.2k | Reduced -10.2k |
| ProShare Advisors LLC 0.00% of their portfolio | 10.2k $35.0k | Reduced -2.0k |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 8.4k $29.0k | Added +5.5k |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 6.9k $23.6k | Reduced -2.5k |
| Ameritas Investment Partners, Inc. 0.00% of their portfolio | 5.5k $18.8k | Unchanged |
| Legal & General Group Plc 0.00% of their portfolio | 5.4k $18.6k | Unchanged |
| STRS OHIO 0.00% of their portfolio | 5.3k $18.2k | Unchanged |
| NISA INVESTMENT ADVISORS, LLC 0.00% of their portfolio | 4.7k $16.3k | Unchanged |
| Sterling Capital Management LLC 0.00% of their portfolio | 4.1k $14.1k | Added +2.5k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 3.7k $12.7k | Reduced -241 |
| JDM Financial Group LLC 0.01% of their portfolio | 3.5k $12.0k | Unchanged |
| Rockefeller Capital Management L.P. 0.00% of their portfolio | 3.0k $10.3k | New |
| Global Retirement Partners, LLC 0.00% of their portfolio | 2.6k $8.8k | New |
| AMALGAMATED BANK 0.00% of their portfolio | 1.6k $6.0k | Unchanged |
| OSAIC HOLDINGS, INC. 0.00% of their portfolio | 1.6k $5.3k | Added +534 |
| PNC Financial Services Group, Inc. 0.00% of their portfolio | 1.2k $4.1k | Reduced -649 |
| EverSource Wealth Advisors, LLC 0.00% of their portfolio | 871 $3.0k | Unchanged |
| NATIONAL BANK OF CANADA /FI/ 0.00% of their portfolio | 655 $2.3k | Unchanged |
| JNBA Financial Advisors 0.00% of their portfolio | 500 $1.7k | Unchanged |
| Farther Finance Advisors, LLC 0.00% of their portfolio | 348 $1.2k | Unchanged |
| CWM, LLC 0.00% of their portfolio | 240 $1.0k | Added +13 |
| Arax Advisory Partners 0.00% of their portfolio | 208 $714 | New |
| TD Waterhouse Canada Inc. 0.00% of their portfolio | 200 $686 | Unchanged |
| Vermillion Wealth Management, Inc. 0.00% of their portfolio | 194 $665 | Unchanged |
| JONES FINANCIAL COMPANIES LLLP 0.00% of their portfolio | 140 $476 | Unchanged |