IRONWOOD PHARMACEUTICALS INC IRWD
COM CL A · Common Stock · CUSIP 46333X108 · ISIN US46333X1081
Company in Cambridge, United States
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersBoston, MA
- Founded1998
- Websiteironwoodpharma.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($1.2m this quarter). Holder counts are more reliable. Shares outstanding: 165.2m as of 2026-07-31, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $4.21. Options: 5 managers hold calls ($1.6m notional), 6 hold puts ($3.2m).
Trends to Q2 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 245 |
| Q4 2022 | 250 |
| Q1 2023 | 256 |
| Q2 2023 | 253 |
| Q3 2023 | 251 |
| Q4 2023 | 252 |
| Q1 2024 | 262 |
| Q2 2024 | 228 |
| Q3 2024 | 222 |
| Q4 2024 | 224 |
| Q1 2025 | 201 |
| Q2 2025 | 156 |
| Q3 2025 | 166 |
| Q4 2025 | 199 |
| Q1 2026 | 227 |
| Q2 2026 | 212 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2024 | 104 | 121 |
| Q4 2024 | 109 | 113 |
| Q1 2025 | 101 | 112 |
| Q2 2025 | 77 | 116 |
| Q3 2025 | 82 | 65 |
| Q4 2025 | 115 | 66 |
| Q1 2026 | 134 | 82 |
| Q2 2026 | 96 | 120 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2025 | $14.7m | $26.4k | 0.00 |
| Q4 2025 | $39.2m | $123.3k | 0.00 |
| Q1 2026 | $40.7m | $2.1m | 0.05 |
| Q2 2026 | $1.6m | $3.2m | 1.98 |
Biggest buyers
| BlackRock, Inc. | Added | +4.4m |
| MACKENZIE FINANCIAL CORP | Added | +1.8m |
| STATE STREET CORP | Added | +1.4m |
| WELLS FARGO & COMPANY/MN | Added | +1.1m |
| MORGAN STANLEY | Added | +1.0m |
| GOLDMAN SACHS GROUP INC | Added | +623.2k |
| HRT FINANCIAL LP | New | +577.3k |
| VANGUARD CAPITAL MANAGEMENT LLC | Added | +511.1k |
| DIMENSIONAL FUND ADVISORS LP | Added | +440.8k |
| JACOBS LEVY EQUITY MANAGEMENT, INC | Added | +433.5k |
Biggest sellers
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | Reduced | -1.4m |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | -1.3m |
| TWO SIGMA INVESTMENTS, LP | Reduced | -1.3m |
| Qube Research & Technologies Ltd | Reduced | -1.2m |
| VANGUARD PORTFOLIO MANAGEMENT LLC | Reduced | -1.2m |
| ARMISTICE CAPITAL, LLC | Reduced | -1.1m |
| AQR CAPITAL MANAGEMENT LLC | Reduced | -1.1m |
| ACADIAN ASSET MANAGEMENT LLC | Reduced | -723.9k |
| UBS Group AG | Reduced | -543.7k |
| JANE STREET GROUP, LLC | Reduced | -492.5k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $666.4k158.3k shares |
| CITADEL ADVISORS LLC | Reduced | $320.0k76.0k shares |
| GROUP ONE TRADING LLC | Reduced | $294.3k69.9k shares |
| SIMPLEX TRADING, LLC | Added | $254.3k60.4k shares |
| Walleye Capital LLC | Added | $69.0k16.4k shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $1.7m396.8k shares |
| SIMPLEX TRADING, LLC | Added | $606.2k144.0k shares |
| CITADEL ADVISORS LLC | Reduced | $413.8k98.3k shares |
| GROUP ONE TRADING LLC | Added | $379.7k90.2k shares |
| JANE STREET GROUP, LLC | Reduced | $66.9k15.9k shares |
| Walleye Capital LLC | Added | $36.6k8.7k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| ARMISTICE CAPITAL, LLC 13G · institution -0.8 pts · filed 2026-08-14 | 8.4% |
| BlackRock, Inc. 13G · institution +1.0 pts · filed 2026-07-28 | 8.1% |
| Sarissa Capital Management LP 13D · may seek influence filed 2026-03-19 | 5.8% |
| STATE STREET CORP 13G · institution +3.2 pts · filed 2026-08-07 | 5.4% |
Fell to 5% or below in the last year: BANK OF AMERICA CORP /DE/ (3.2%, 2026-10-28), RENAISSANCE TECHNOLOGIES LLC (4.9%, 2026-05-14), VANGUARD GROUP INC (0.0%, 2026-03-27)
Insider purchases and sales since 1 Apr 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2024 | 0 | — | 2 | $66.8k | — |
| Q1 2025 | 0 | — | 5 | $428.3k | — |
| Q2 2025 | 0 | — | 2 | $9.2k | — |
| Q3 2025 | 0 | — | 4 | $11.1k | — |
| Q4 2025 | 0 | — | 1 | $20.0k | — |
| Q1 2026 | 0 | — | 7 | $21.9m | $162.9k |
| Q2 2026 | 0 | — | 1 | $80.5k | $80.5k |
| Q3 2026 | 0 | — | 1 | $578.1k | $578.1k |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2026-07-07 | Silver Ronald PFO & PAO | Sold plan | $578.1k127.9k shares |
| 2026-06-16 | McHugh Julie Director | Sold plan | $80.5k21.6k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2026
| Manager | Shares | Change |
|---|---|---|
| BlackRock, Inc. 0.00% of their portfolio | 17.8m $74.9m | Added +4.4m |
| ARMISTICE CAPITAL, LLC 1.62% of their portfolio | 13.9m $58.7m | Reduced -1.1m |
| Sarissa Capital Management LP 21.75% of their portfolio | 9.2m $38.7m | Unchanged |
| STATE STREET CORP 0.00% of their portfolio | 8.8m $37.1m | Added +1.4m |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 8.7m $36.6m | Added +896 |
| RENAISSANCE TECHNOLOGIES LLC 0.05% of their portfolio | 8.0m $33.7m | Reduced -67.8k |
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 6.6m $27.8m | Added +511.1k |
| AQR CAPITAL MANAGEMENT LLC 0.01% of their portfolio | 6.5m $27.2m | Reduced -1.1m |
| ACADIAN ASSET MANAGEMENT LLC 0.03% of their portfolio | 5.9m $24.6m | Reduced -723.9k |
| VANGUARD PORTFOLIO MANAGEMENT LLC 0.00% of their portfolio | 5.5m $23.2m | Reduced -1.2m |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 4.8m $20.3m | Added +288.1k |
| TWO SIGMA INVESTMENTS, LP 0.01% of their portfolio | 4.6m $19.2m | Reduced -1.3m |
| MARSHALL WACE, LLP 0.02% of their portfolio | 4.3m $18.1m | Reduced -235.0k |
| JACOBS LEVY EQUITY MANAGEMENT, INC 0.06% of their portfolio | 4.1m $17.1m | Added +433.5k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 3.3m $14.0m | Added +623.2k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 3.3m $13.9m | Reduced -1.4m |
| FEDERATED HERMES, INC. 0.02% of their portfolio | 3.2m $13.6m | Reduced -117.6k |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP 0.01% of their portfolio | 3.0m $12.7m | Reduced -380.2k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 2.5m $10.6m | Added +440.8k |
| MACKENZIE FINANCIAL CORP 0.01% of their portfolio | 2.4m $10.0m | Added +1.8m |
| MORGAN STANLEY 0.00% of their portfolio | 1.9m $7.8m | Added +1.0m |
| Connor, Clark & Lunn Investment Management Ltd. 0.01% of their portfolio | 1.8m $7.6m | Reduced -23.7k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 1.4m $5.8m | Added +108.1k |
| Hillsdale Investment Management Inc. 0.12% of their portfolio | 1.3m $5.3m | Added +13.8k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 1.2m $5.1m | Added +1.1m |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 1.2m $4.9m | Added +33.1k |
| Pacer Advisors, Inc. 0.01% of their portfolio | 1.1m $4.6m | Reduced -39.0k |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 1.0m $4.4m | Added +51.7k |
| FRANKLIN RESOURCES INC 0.00% of their portfolio | 1.0m $4.2m | Added +262.3k |
| FMR LLC 0.00% of their portfolio | 909.5k $3.8m | Added +119.1k |
| STATE OF WISCONSIN INVESTMENT BOARD 0.01% of their portfolio | 778.5k $3.3m | Added +180.4k |
| RAYMOND JAMES FINANCIAL INC 0.00% of their portfolio | 725.1k $3.1m | Reduced -38.9k |
| VICTORY CAPITAL MANAGEMENT INC 0.00% of their portfolio | 658.5k $2.8m | Reduced -54.7k |
| Inspire Investing, LLC 0.11% of their portfolio | 630.1k $2.7m | Added +120.1k |
| HRT FINANCIAL LP 0.01% of their portfolio | 577.3k $2.4m | New |
| IEQ CAPITAL, LLC 0.01% of their portfolio | 561.6k $2.4m | Reduced -181.1k |
| Vanguard Global Advisers, LLC 0.00% of their portfolio | 561.0k $2.4m | Reduced -30.5k |
| PRUDENTIAL FINANCIAL INC 0.00% of their portfolio | 537.2k $2.3m | Added +87.4k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 508.9k $2.1m | Added +24.8k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 502.4k $2.1m | Added +384.1k |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 484.4k $2.0m | Added +338.6k |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 468.8k $2.0m | Added +15.3k |
| SEI INVESTMENTS CO 0.00% of their portfolio | 459.4k $1.9m | Reduced -283.1k |
| O'SHAUGHNESSY ASSET MANAGEMENT, LLC 0.01% of their portfolio | 438.9k $1.8m | Added +310.7k |
| WEDGE CAPITAL MANAGEMENT L L P/NC 0.03% of their portfolio | 435.6k $1.8m | Reduced -104.8k |
| SEGALL BRYANT & HAMILL, LLC 0.02% of their portfolio | 408.1k $1.7m | Added +129.9k |
| Invesco Ltd. 0.00% of their portfolio | 403.2k $1.7m | Reduced -144.2k |
| Man Group plc 0.00% of their portfolio | 392.1k $1.7m | Reduced -148.7k |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.03% of their portfolio | 389.8k $1.6m | Reduced -50.7k |
| UBS Group AG 0.00% of their portfolio | 389.5k $1.6m | Reduced -543.7k |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.00% of their portfolio | 375.3k $1.6m | Unchanged |
| RITHOLTZ WEALTH MANAGEMENT 0.02% of their portfolio | 360.1k $1.5m | Added +272.6k |
| Nuveen, LLC 0.00% of their portfolio | 355.4k $1.5m | Added +122.0k |
| CM Management, LLC 0.94% of their portfolio | 350.0k $1.5m | Unchanged |
| Qube Research & Technologies Ltd 0.00% of their portfolio | 348.0k $1.5m | Reduced -1.2m |
| Robeco Institutional Asset Management B.V. 0.00% of their portfolio | 343.0k $1.4m | Unchanged |
| LOS ANGELES CAPITAL MANAGEMENT LLC 0.01% of their portfolio | 342.3k $1.4m | Reduced -167.0k |
| Virtus Investment Advisers, LLC 0.31% of their portfolio | 318.6k $1.3m | Added +242.4k |
| LSV ASSET MANAGEMENT 0.00% of their portfolio | 308.3k $1.3m | Unchanged |
| CWA Asset Management Group, LLC 0.04% of their portfolio | 290.4k $1.2m | New |
| GLOBEFLEX CAPITAL L P 0.14% of their portfolio | 259.8k $1.1m | Unchanged |
| GSA CAPITAL PARTNERS LLP 0.07% of their portfolio | 259.5k $1.1m | Reduced -394.9k |
| CITIGROUP INC 0.00% of their portfolio | 226.8k $954.9k | Added +187.4k |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 224.8k $946.5k | Reduced -37.0k |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC 0.00% of their portfolio | 219.4k $913.3k | Reduced -7.2k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 212.6k $914.1k | Added +94.4k |
| Cerity Partners LLC 0.00% of their portfolio | 208.0k $875.8k | Reduced -160.4k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 205.1k $863.4k | Added +12.2k |
| MARTINGALE ASSET MANAGEMENT L P 0.02% of their portfolio | 205.0k $863.0k | Unchanged |
| EVOLVE PRIVATE WEALTH, LLC 0.05% of their portfolio | 186.9k $786.7k | Added +171.4k |
| Vident Advisory, LLC 0.01% of their portfolio | 180.9k $761.7k | Reduced -3.4k |
| Creative Planning 0.00% of their portfolio | 177.0k $745.3k | Reduced -490 |
| KLP KAPITALFORVALTNING AS 0.00% of their portfolio | 174.2k $733.4k | Unchanged |
| Mariner, LLC 0.00% of their portfolio | 168.5k $709.3k | Reduced -39.3k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 165.8k $581.9k | Unchanged |
| OMERS ADMINISTRATION Corp 0.00% of their portfolio | 159.0k $669.4k | Reduced -67.3k |
| Rafferty Asset Management, LLC 0.00% of their portfolio | 152.9k $643.6k | Reduced -63.7k |
| Quantinno Capital Management LP 0.00% of their portfolio | 150.6k $634.0k | Added +20.9k |
| FIFTH THIRD BANCORP 0.00% of their portfolio | 132.7k $558.9k | Reduced -32.3k |
| CANADA PENSION PLAN INVESTMENT BOARD 0.00% of their portfolio | 130.9k $551.1k | Reduced -4.1k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 129.7k $546.0k | Reduced -492.5k |
| SG Americas Securities, LLC 0.00% of their portfolio | 129.3k $544.0k | Added +15.7k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 129.2k $544.1k | Reduced -1.3m |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 128.8k $543.0k | Added +4.5k |
| Arax Advisory Partners 0.00% of their portfolio | 127.0k $534.5k | Added +125.3k |
| MERCER GLOBAL ADVISORS INC /ADV 0.00% of their portfolio | 126.2k $531.1k | Added +11.1k |
| HSBC HOLDINGS PLC 0.00% of their portfolio | 126.1k $541.6k | Added +96.4k |
| D. E. Shaw & Co., Inc. 0.00% of their portfolio | 122.9k $517.4k | Added +75.0k |
| Optimist Retirement Group LLC 0.17% of their portfolio | 102.1k $429.6k | Added +7.2k |
| State of Wyoming 0.04% of their portfolio | 101.8k $428.5k | Reduced -26.4k |
| Cercano Management LLC 0.06% of their portfolio | 101.4k $426.8k | Unchanged |
| BARCLAYS PLC 0.00% of their portfolio | 100.1k $421.5k | Added +10.2k |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 99.5k $419.0k | Added +185 |
| Engineers Gate Manager LP 0.01% of their portfolio | 98.1k $412.8k | Added +18.2k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 96.2k $405.0k | Added +32.4k |
| Integrated Quantitative Investments LLC 0.06% of their portfolio | 93.7k $394.4k | Reduced -458.4k |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 93.2k $393.9k | Added +3.1k |
| FULLER & THALER ASSET MANAGEMENT, INC. 0.00% of their portfolio | 90.3k $380.3k | Reduced -760 |
| WINTON GROUP Ltd 0.01% of their portfolio | 84.2k $354.3k | Reduced -157.6k |
| Allspring Global Investments Holdings, LLC 0.00% of their portfolio | 82.3k $339.1k | Added +3.1k |