INTELLIA THERAPEUTICS INC NTLA
COM · Common Stock · CUSIP 45826J105 · ISIN US45826J1051
It is a biotechnology company developing biopharmaceuticals using a CRISPR gene editing system.
- SectorHealth care
- IndustryIn Vitro & In Vivo Diagnostic Substances
- HeadquartersCambridge, MA
- Founded2014
- Websiteintelliatx.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($79.3m this quarter). Holder counts are more reliable. Shares outstanding: 101.6m as of 2024-08-02, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $22.38. Options: 16 managers hold calls ($18.7m notional), 13 hold puts ($27.6m).
Trends to Q2 2024
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 321 |
| Q4 2022 | 306 |
| Q1 2023 | 291 |
| Q2 2023 | 293 |
| Q3 2023 | 290 |
| Q4 2023 | 294 |
| Q1 2024 | 285 |
| Q2 2024 | 292 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 163 | 139 |
| Q1 2023 | 140 | 137 |
| Q2 2023 | 139 | 109 |
| Q3 2023 | 153 | 103 |
| Q4 2023 | 160 | 117 |
| Q1 2024 | 152 | 130 |
| Q2 2024 | 158 | 125 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2023 | $13.4m | $12.8m | 0.96 |
| Q4 2023 | $21.1m | $30.2m | 1.43 |
| Q1 2024 | $21.7m | $23.0m | 1.06 |
| Q2 2024 | $18.7m | $27.6m | 1.48 |
Biggest buyers
| ARK Investment Management LLC | Added | +606.5k |
| Deep Track Capital, LP | Added | +589.2k |
| Contrarius Investment Management Ltd | Added | +564.9k |
| BlackRock Inc. | Added | +488.3k |
| Nuveen Asset Management, LLC | Added | +481.8k |
| FEDERATED HERMES, INC. | Added | +371.2k |
| JPMORGAN CHASE & CO | Added | +252.0k |
| GEODE CAPITAL MANAGEMENT, LLC | Added | +249.7k |
| TWO SIGMA INVESTMENTS, LP | Added | +214.7k |
| ALLIANCEBERNSTEIN L.P. | Added | +211.4k |
Biggest sellers
| MORGAN STANLEY | Reduced | -5.6m |
| WELLINGTON MANAGEMENT GROUP LLP | Reduced | -3.4m |
| PRICE T ROWE ASSOCIATES INC /MD/ | Reduced | -380.1k |
| NORGES BANK | Reduced | -373.7k |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | Reduced | -343.1k |
| MARSHALL WACE, LLP | Sold out | -335.4k |
| Rokos Capital Management LLP | Reduced | -322.7k |
| STATE STREET CORP | Reduced | -235.0k |
| CITIGROUP INC | Reduced | -234.6k |
| Squarepoint Ops LLC | Reduced | -232.5k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $6.6m296.9k shares |
| CITADEL ADVISORS LLC | Added | $2.8m126.8k shares |
| JANE STREET GROUP, LLC | Added | $1.8m81.8k shares |
| SIMPLEX TRADING, LLC | Added | $1.6m71.1k shares |
| WOLVERINE TRADING, LLC | Added | $1.1m47.0k shares |
| BARCLAYS PLC | Reduced | $1.0m45.4k shares |
| CAPITAL FUND MANAGEMENT S.A. | Reduced | $984.7k44.0k shares |
| GROUP ONE TRADING LLC | Reduced | $884.0k39.5k shares |
| Caption Management, LLC | Reduced | $559.5k25.0k shares |
| Walleye Capital LLC | Added | $503.6k22.5k shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $8.8m394.0k shares |
| JANE STREET GROUP, LLC | Added | $6.4m287.6k shares |
| CITADEL ADVISORS LLC | Added | $2.9m128.7k shares |
| Walleye Capital LLC | Added | $2.7m121.6k shares |
| SIMPLEX TRADING, LLC | Reduced | $1.6m71.8k shares |
| PEAK6 Investments LLC | Added | $1.2m52.5k shares |
| Walleye Trading LLC | Added | $1.1m50.5k shares |
| Caption Management, LLC | Unchanged | $810.2k36.2k shares |
| D. E. Shaw & Co., Inc. | New | $671.4k30.0k shares |
| WOLVERINE TRADING, LLC | Added | $512.5k22.9k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| ARK Investment Management LLC 13G · institution +1.2 pts · filed 2026-02-03 | 12.3% |
| BlackRock, Inc. 13G · institution filed 2025-04-17 | 8.2% |
| STATE STREET CORP 13G · institution +1.3 pts · filed 2026-08-07 | 6.8% |
| VANGUARD PORTFOLIO MANAGEMENT LLC 13G · institution new · filed 2026-04-29 | 5.3% |
| VANGUARD CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-04-30 | 5.0% |
Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-27; now reported by VANGUARD PORTFOLIO MANAGEMENT LLC), GOLDMAN SACHS GROUP INC (2.7%, 2026-02-12), Contrarius Investment Management Ltd (0.6%, 2026-02-11)
Insider purchases and sales in Q2 2024
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q3 2022 | 0 | — | 1 | $5.4k | — |
| Q4 2022 | 0 | — | 0 | — | — |
| Q1 2023 | 0 | — | 7 | $845.8k | — |
| Q2 2023 | 0 | — | 1 | $225.0k | $225.0k |
| Q3 2023 | 0 | — | 2 | $99.2k | $84.6k |
| Q4 2023 | 0 | — | 1 | $6.3k | $6.3k |
| Q1 2024 | 0 | — | 7 | $1.6m | $65.7k |
| Q2 2024 | 0 | — | 1 | $37.6k | $37.6k |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2024-06-17 | Verwiel Frank Director | Sold plan | $37.6k1.5k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2024
| Manager | Shares | Change |
|---|---|---|
| ARK Investment Management LLC 2.30% of their portfolio | 11.6m $259.5m | Added +606.5k |
| BlackRock Inc. 0.00% of their portfolio | 9.6m $214.8m | Added +488.3k |
| VANGUARD GROUP INC 0.00% of their portfolio | 9.1m $203.7m | Added +6.4k |
| Deep Track Capital, LP 3.21% of their portfolio | 4.8m $107.4m | Added +589.2k |
| STATE STREET CORP 0.00% of their portfolio | 4.4m $97.6m | Reduced -235.0k |
| Sumitomo Mitsui Trust Group, Inc. 0.05% of their portfolio | 3.3m $72.9m | Reduced -141.6k |
| Amova Asset Management Americas, Inc. 0.84% of their portfolio | 3.3m $72.9m | Reduced -141.6k |
| MORGAN STANLEY 0.00% of their portfolio | 2.3m $52.3m | Reduced -5.6m |
| FEDERATED HERMES, INC. 0.12% of their portfolio | 2.3m $51.5m | Added +371.2k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 2.3m $51.3m | Added +249.7k |
| FMR LLC 0.00% of their portfolio | 2.2m $49.9m | Added +22.1k |
| Casdin Capital, LLC 3.42% of their portfolio | 2.0m $44.8m | Added +125.0k |
| Contrarius Investment Management Ltd 2.68% of their portfolio | 1.9m $42.9m | Added +564.9k |
| ALLIANCEBERNSTEIN L.P. 0.01% of their portfolio | 1.8m $39.9m | Added +211.4k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 1.3m $29.9m | Added +252.0k |
| DIMENSIONAL FUND ADVISORS LP 0.01% of their portfolio | 1.3m $29.6m | Added +98.9k |
| GOLDMAN SACHS GROUP INC 0.01% of their portfolio | 1.3m $28.3m | Added +199.1k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 1.2m $27.9m | Reduced -380.1k |
| Rokos Capital Management LLP 0.59% of their portfolio | 1.1m $25.5m | Reduced -322.7k |
| Chevy Chase Trust Holdings, LLC 0.07% of their portfolio | 1.0m $23.3m | Reduced -32.0k |
| HIMENSION CAPITAL (SINGAPORE) PTE. LTD. 1.63% of their portfolio | 1.0m $23.1m | Reduced -639 |
| Nuveen Asset Management, LLC 0.01% of their portfolio | 865.6k $19.4m | Added +481.8k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 835.4k $18.7m | Reduced -35.9k |
| TWO SIGMA INVESTMENTS, LP 0.04% of their portfolio | 829.3k $18.6m | Added +214.7k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 789.8k $17.7m | Added +61.5k |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 781.8k $17.5m | Reduced -3.4m |
| TWO SIGMA ADVISERS, LP 0.04% of their portfolio | 769.9k $17.2m | Added +110.6k |
| CITADEL ADVISORS LLC 0.02% of their portfolio | 762.7k $17.1m | Reduced -128.1k |
| Pictet Asset Management Holding SA 0.02% of their portfolio | 744.0k $16.7m | Reduced -61.1k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 647.7k $14.5m | Added +21.3k |
| Discovery Value Fund 6.39% of their portfolio | 561.6k $12.6m | Unchanged |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 512.3k $11.5m | Added +132.7k |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC 0.04% of their portfolio | 452.4k $10.1m | Reduced -343.1k |
| MPM BIOIMPACT LLC 1.54% of their portfolio | 443.5k $9.9m | Added +10.9k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 364.3k $8.2m | Added +2.3k |
| Vestmark Advisory Solutions, Inc. 0.33% of their portfolio | 355.3k $8.0m | Reduced -65.1k |
| Balyasny Asset Management L.P. 0.02% of their portfolio | 347.5k $7.8m | Added +159.0k |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 330.5k $7.4m | Added +63.5k |
| CAPITAL ADVISORS INC/OK 0.14% of their portfolio | 311.0k $7.0m | Added +10.4k |
| Temasek Holdings (Private) Ltd 0.03% of their portfolio | 279.7k $6.3m | Unchanged |
| Hudson Bay Capital Management LP 0.05% of their portfolio | 275.0k $6.2m | Added +27.7k |
| UBS Group AG 0.00% of their portfolio | 255.6k $5.7m | Reduced -76.0k |
| PINNACLE ASSOCIATES LTD 0.09% of their portfolio | 251.1k $5.6m | Reduced -4.6k |
| JANE STREET GROUP, LLC 0.01% of their portfolio | 245.4k $5.5m | Added +151.6k |
| Aberdeen Group plc 0.01% of their portfolio | 243.0k $5.4m | Added +88.8k |
| NORGES BANK 0.00% of their portfolio | 240.4k $5.4m | Reduced -373.7k |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.01% of their portfolio | 234.8k $5.3m | First filing |
| PDT Partners, LLC 0.48% of their portfolio | 227.2k $5.1m | Added +4.2k |
| Rafferty Asset Management, LLC 0.02% of their portfolio | 225.2k $5.0m | Reduced -98.3k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.01% of their portfolio | 220.6k $4.9m | Added +121.1k |
| Opaleye Management Inc. 1.11% of their portfolio | 218.0k $4.9m | Reduced -37.0k |
| Granahan Investment Management, LLC 0.19% of their portfolio | 214.9k $4.8m | Reduced -5.3k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 212.5k $4.8m | Reduced -1.6k |
| RAYMOND JAMES & ASSOCIATES 0.00% of their portfolio | 207.3k $4.6m | Added +52.7k |
| BARCLAYS PLC 0.00% of their portfolio | 203.4k $4.6m | Added +18.1k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 201.7k $4.5m | Reduced -14.1k |
| Schonfeld Strategic Advisors LLC 0.03% of their portfolio | 186.4k $4.2m | Added +160.7k |
| Swiss National Bank 0.00% of their portfolio | 180.3k $4.0m | Added +12.4k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 175.3k $3.9m | Added +8.8k |
| NEUBERGER BERMAN GROUP LLC 0.00% of their portfolio | 171.4k $3.8m | Added +37.6k |
| Trexquant Investment LP 0.06% of their portfolio | 170.8k $3.8m | New |
| Orchard Capital Management, LLC 1.15% of their portfolio | 170.0k $3.8m | Reduced -2.3k |
| Avidity Partners Management LP 0.16% of their portfolio | 170.0k $3.8m | New |
| Russell Investments Group, Ltd. 0.01% of their portfolio | 150.6k $3.4m | Added +40.3k |
| NEOS Investment Management LLC 0.14% of their portfolio | 149.6k $3.3m | Added +75.0k |
| SPHERA FUNDS MANAGEMENT LTD. 0.51% of their portfolio | 139.4k $3.1m | New |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND 0.01% of their portfolio | 138.5k $3.1m | Reduced -99.5k |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 131.0k $2.9m | Added +56.5k |
| California Public Employees Retirement System 0.00% of their portfolio | 127.4k $2.9m | Added +811 |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA 1.44% of their portfolio | 117.3k $2.6m | Unchanged |
| LAZARD ASSET MANAGEMENT LLC 0.00% of their portfolio | 116.4k $2.6m | Added +26.3k |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 114.7k $2.6m | Reduced -384 |
| CITIGROUP INC 0.00% of their portfolio | 108.4k $2.4m | Reduced -234.6k |
| Rockefeller Capital Management L.P. 0.01% of their portfolio | 100.9k $2.3m | Added +24.6k |
| TWINBEECH CAPITAL LP 0.04% of their portfolio | 100.0k $2.2m | New |
| Invesco Ltd. 0.00% of their portfolio | 96.0k $2.1m | Reduced -665 |
| STIFEL FINANCIAL CORP 0.00% of their portfolio | 91.5k $2.0m | Added +7.4k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 89.9k $2.0m | Added +4.3k |
| Legal & General Group Plc 0.00% of their portfolio | 87.6k $2.0m | Added +1.0k |
| SCHRODER INVESTMENT MANAGEMENT GROUP 0.00% of their portfolio | 86.5k $1.9m | Reduced -441 |
| State of New Jersey Common Pension Fund D 0.01% of their portfolio | 85.8k $1.9m | Reduced -15.0k |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 75.7k $1.7m | Reduced -103.2k |
| ALPS ADVISORS INC 0.01% of their portfolio | 75.2k $1.7m | Added +7.5k |
| DekaBank Deutsche Girozentrale 0.00% of their portfolio | 75.0k $1.8m | Unchanged |
| McGuire Investment Group, LLC 0.23% of their portfolio | 72.0k $1.6m | Reduced -4.5k |
| GSA CAPITAL PARTNERS LLP 0.11% of their portfolio | 70.4k $1.6m | New |
| ALGERT GLOBAL LLC 0.05% of their portfolio | 68.4k $1.5m | Added +51.6k |
| Elmwood Wealth Management, Inc. 0.67% of their portfolio | 67.2k $1.5m | Reduced -725 |
| TUDOR INVESTMENT CORP ET AL 0.02% of their portfolio | 61.8k $1.4m | Added +14.3k |
| Engineers Gate Manager LP 0.03% of their portfolio | 61.5k $1.4m | New |
| GUGGENHEIM CAPITAL LLC 0.01% of their portfolio | 61.3k $1.4m | Reduced -2.2k |
| BENJAMIN F. EDWARDS & COMPANY, INC. 0.02% of their portfolio | 60.9k $1.4m | Added +60.1k |
| CAPSTONE INVESTMENT ADVISORS, LLC 0.03% of their portfolio | 60.3k $1.3m | New |
| SIT INVESTMENT ASSOCIATES INC 0.03% of their portfolio | 59.9k $1.3m | Added +22.4k |
| Intellectus Partners, LLC 0.36% of their portfolio | 58.2k $1.3m | Added +1.2k |
| LPL Financial LLC 0.00% of their portfolio | 57.3k $1.3m | Added +5.7k |
| SEVEN EIGHT CAPITAL, LP 0.13% of their portfolio | 56.4k $1.3m | New |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 56.2k $1.3m | Reduced -2.3k |
| MetLife Investment Management, LLC 0.01% of their portfolio | 55.7k $1.2m | Added +9.2k |
| ENVESTNET ASSET MANAGEMENT INC 0.00% of their portfolio | 55.6k $1.2m | Added +4.3k |