Vault-13

INSMED INC INSM

COM PAR $.01 · Common Stock · CUSIP 457669307 · ISIN US4576693075

380 institutional holders +90 vs Q1 2024
178,764,322178.8m shares reported held*
104.0% of all shares outstanding*
$12.0bnreported value*
125 new 132 added 100 reduced 37 sold out net bought ≈ $1.7bn (+26.0m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($15.4m this quarter). Holder counts are more reliable. Shares outstanding: 171.8m as of 2024-08-02, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $67.00. Options: 38 managers hold calls ($470.9m notional), 28 hold puts ($343.5m).

Trends to Q2 2024

Institutional holders

Managers reporting a position, each quarter

0200400Q3 22: 239Q4 22: 226Q1 23: 232Q2 23: 225Q3 23: 254Q4 23: 273Q1 24: 290Q2 24: 380380Q3 22Q1 23Q3 23Q1 24Q2 24
Numbers
QuarterHolders
Q3 2022239
Q4 2022226
Q1 2023232
Q2 2023225
Q3 2023254
Q4 2023273
Q1 2024290
Q2 2024380

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
4000400Q4 22: 132 bought or addedQ4 22: 104 cut or sold outQ4 22Q1 23: 123 bought or addedQ1 23: 97 cut or sold outQ2 23: 103 bought or addedQ2 23: 111 cut or sold outQ2 23Q3 23: 133 bought or addedQ3 23: 95 cut or sold outQ4 23: 131 bought or addedQ4 23: 111 cut or sold outQ4 23Q1 24: 141 bought or addedQ1 24: 126 cut or sold outQ2 24: 257 bought or addedQ2 24: 137 cut or sold outQ2 24
Numbers
QuarterBought or addedCut or sold out
Q4 2022132104
Q1 202312397
Q2 2023103111
Q3 202313395
Q4 2023131111
Q1 2024141126
Q2 2024257137

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$200m$400m$600mQ3 23 calls: $9.3mQ3 23 puts: $40.6mQ3 23P/C 4.38Q4 23 calls: $10.0mQ4 23 puts: $52.2mQ4 23P/C 5.19Q1 24 calls: $68.3mQ1 24 puts: $84.5mQ1 24P/C 1.24Q2 24 calls: $470.9mQ2 24 puts: $343.5mQ2 24P/C 0.73
Numbers
QuarterCallsPutsP/C
Q3 2023$9.3m$40.6m4.38
Q4 2023$10.0m$52.2m5.19
Q1 2024$68.3m$84.5m1.24
Q2 2024$470.9m$343.5m0.73

Biggest buyers

JPMORGAN CHASE & CO Added +5,273,308+5.3m
Capital International Investors Added +4,249,074+4.2m
Darwin Global Management, Ltd. New +3,541,095+3.5m
BAKER BROS. ADVISORS LP Added +3,233,038+3.2m
Artisan Partners Limited Partnership New +2,489,431+2.5m
BlackRock Inc. Added +2,464,794+2.5m
RTW INVESTMENTS, LP Added +1,775,000+1.8m
VANGUARD GROUP INC Added +1,503,775+1.5m
PRICE T ROWE ASSOCIATES INC /MD/ Added +1,394,002+1.4m
LORD, ABBETT & CO. LLC New +1,165,154+1.2m

Biggest sellers

Deep Track Capital, LP Reduced -2,783,679-2.8m
Palo Alto Investors LP Reduced -2,284,406-2.3m
FMR LLC Reduced -2,013,764-2.0m
MORGAN STANLEY Reduced -1,996,005-2.0m
FIRST TRUST ADVISORS LP Reduced -1,381,726-1.4m
STATE STREET CORP Reduced -1,242,688-1.2m
MACQUARIE GROUP LTD Reduced -1,152,876-1.2m
Bellevue Group AG Reduced -1,120,143-1.1m
T. Rowe Price Investment Management, Inc. Reduced -1,015,618-1.0m
FRANKLIN RESOURCES INC Reduced -848,723-848.7k

Biggest calls

Caption Management, LLC Added $79.4m1.2m shares
Kynam Capital Management, LP New $67.0m1.0m shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Added $42.2m630.3k shares
Ikarian Capital, LLC Reduced $34.0m5.1k shares
JPMORGAN CHASE & CO Added $24.5m365.2k shares
Twin Tree Management, LP New $21.3m318.6k shares
SILVERARC CAPITAL MANAGEMENT, LLC New $16.8m250.0k shares
Octagon Capital Advisors LP New $16.8m250.0k shares
NOMURA HOLDINGS INC New $15.7m234.5k shares
GROUP ONE TRADING LLC Added $14.6m217.5k shares

Biggest puts

Sio Capital Management, LLC Unchanged $91.3m1.4m shares
Caption Management, LLC Added $69.5m1.0m shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Added $50.7m757.2k shares
Parallax Volatility Advisers, L.P. Added $35.0m522.7k shares
CITADEL ADVISORS LLC Added $21.2m315.8k shares
ADAR1 Capital Management, LLC Added $13.5m200.8k shares
UBS Group AG New $8.6m128.2k shares
BOOTHBAY FUND MANAGEMENT, LLC Added $6.8m101.9k shares
Twin Tree Management, LP New $5.2m77.4k shares
Ikarian Capital, LLC Reduced $4.8m709 shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
FMR LLC 13G · institution +1.3 pts · filed 2026-08-06 7.4% +1.3 pts 16.1m≈ $1.7bn 2026-08-06
BlackRock, Inc. 13G · institution +1.5 pts · filed 2026-01-21 6.6% +1.5 pts 14.1m≈ $1.5bn 2026-01-21
VANGUARD CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-04-30 5.3% new 11.5m≈ $1.2bn 2026-04-30

Fell to 5% or below in the last year: Darwin Global Management, Ltd. (3.0%, 2026-08-14), JPMORGAN CHASE & CO (4.7%, 2026-07-22), VANGUARD GROUP INC (0.0%, 2026-03-27; now reported by VANGUARD CAPITAL MANAGEMENT LLC), PRICE T ROWE ASSOCIATES INC /MD/ (3.3%, 2025-11-14)

Insider purchases and sales in Q2 2024

Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.

Officers and directors buying vs selling

Number of people, by quarter (10% owners not included)

BuyingSelling
10010Q3 22: 0 buyingQ3 22: 3 sellingQ4 22: 2 buyingQ4 22: 2 sellingQ4 22Q1 23: 0 buyingQ1 23: 7 sellingQ2 23: 1 buyingQ2 23: 7 sellingQ2 23Q3 23: 0 buyingQ3 23: 1 sellingQ4 23: 0 buyingQ4 23: 4 sellingQ4 23Q1 24: 0 buyingQ1 24: 7 sellingQ2 24: 0 buyingQ2 24: 7 sellingQ2 24
Numbers
QuarterBuyingBoughtSellingSoldSold under a plan
Q3 20220—3$8.3m—
Q4 20222$1.3m2$357.7k—
Q1 20230—7$679.5k—
Q2 20231$385.8k7$1.2m$344.4k
Q3 20230—1$14.9k—
Q4 20230—4$4.7m$4.7m
Q1 20240—7$3.7m$3.0m
Q2 20240—7$28.7m$26.9m
DateInsiderTradeSharesPrice ValueTheir holding
2024-06-10 Flammer Martina M.D. Chief Medical Officer Sold plan 21,195 $60.00 $1.3m21.2k shares -17%
2024-06-03 Schaeffer Orlov S Nicole Chief People Strategy Officer Sold plan 55,000 $55.33 $3.0m55.0k shares -34%
2024-05-30 Flammer Martina M.D. Chief Medical Officer Sold plan 21,195 $55.00 $1.2m21.2k shares -17%
2024-05-29 Bonstein Sara Chief Financial Officer Sold plan 220,564 $50.00 $11.0m220.6k shares -65%
2024-05-28 Flammer Martina M.D. Chief Medical Officer Sold plan 103,806 $49.62 $5.2m103.8k shares -49%
2024-05-28 Smith Michael Alexander Chief Legal Officer Sold plan 44,722 $49.53 $2.2m44.7k shares -34%
2024-05-28 Schaeffer Orlov S Nicole Chief People Strategy Officer Sold plan 27,500 $49.53 $1.4m27.5k shares -20%
2024-05-28 Bonstein Sara Chief Financial Officer Sold plan 20,724 $50.01 $1.0m20.7k shares -6%
2024-05-28 Wise John Drayton Chief Commercial Officer Sold plan 7,852 $49.79 $390.9k7.9k shares -6%
2024-05-17 Adsett Roger Chief Operating Officer Sold plan 5,945 $25.09 $149.2k5.9k shares -4%
2024-05-17 Flammer Martina M.D. Chief Medical Officer Sold plan 4,642 $25.09 $116.5k4.6k shares -4%
2024-05-14 Lewis William Chair and CEO, director Sold 22,198 $25.52 $566.5k22.2k shares -6%
2024-05-14 Bonstein Sara Chief Financial Officer Sold 11,088 $25.32 $280.7k11.1k shares -9%
2024-05-14 Flammer Martina M.D. Chief Medical Officer Sold 10,640 $25.47 $271.0k10.6k shares -9%
2024-05-14 Adsett Roger Chief Operating Officer Sold 7,857 $25.50 $200.4k7.9k shares -5%
2024-05-14 Schaeffer Orlov S Nicole Chief People Strategy Officer Sold 6,508 $25.53 $166.1k6.5k shares -6%
2024-05-14 Wise John Drayton Chief Commercial Officer Sold 5,088 $25.47 $129.6k5.1k shares -4%
2024-05-14 Smith Michael Alexander Chief Legal Officer Sold 5,093 $25.40 $129.4k5.1k shares -5%

Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).

Holders, Q2 2024

#ManagerLocationShares Value% of their portfolioChangeShares change
1 VANGUARD GROUP INC 0.02% of their portfolio Valley Forge, PA 16,013,01016.0m $1.1bn $1.1bn 0.02% Added +1.5m +1,503,775
2 BlackRock Inc. 0.02% of their portfolio New York, NY 14,264,49514.3m $955.7m $955.7m 0.02% Added +2.5m +2,464,794
3 PRICE T ROWE ASSOCIATES INC /MD/ 0.10% of their portfolio BALTIMORE, MD 12,163,36812.2m $814.9m $814.9m 0.10% Added +1.4m +1,394,002
4 FMR LLC 0.03% of their portfolio BOSTON, MA 7,305,1307.3m $489.4m $489.4m 0.03% Reduced -2.0m -2,013,764
5 Capital International Investors 0.08% of their portfolio Los Angeles, CA 5,869,8885.9m $393.3m $393.3m 0.08% Added +4.2m +4,249,074
6 JPMORGAN CHASE & CO 0.02% of their portfolio NEW YORK, NY 5,852,3705.9m $392.1m $392.1m 0.02% Added +5.3m +5,273,308
7 STATE STREET CORP 0.01% of their portfolio BOSTON, MA 4,662,4394.7m $312.4m $312.4m 0.01% Reduced -1.2m -1,242,688
8 GEODE CAPITAL MANAGEMENT, LLC 0.02% of their portfolio BOSTON, MA 3,640,7203.6m $244.0m $244.0m 0.02% Added +477.0k +476,969
9 RTW INVESTMENTS, LP 3.78% of their portfolio NEW YORK, NY 3,640,1083.6m $243.9m $243.9m 3.78% Added +1.8m +1,775,000
10 BAKER BROS. ADVISORS LP 3.06% of their portfolio NEW YORK, NY 3,576,0383.6m $239.6m $239.6m 3.06% Added +3.2m +3,233,038
11 Darwin Global Management, Ltd. 27.58% of their portfolio ST. HELIER, Y9 3,541,0953.5m $237.1m $237.1m 27.58% New
12 WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC 0.61% of their portfolio CHICAGO, IL 3,469,7283.5m $232.5m $232.5m 0.61% Reduced -745.0k -744,991
13 MACQUARIE GROUP LTD 0.21% of their portfolio Sydney, NSW 2000, C3 2,746,6282.7m $184.0m $184.0m 0.21% Reduced -1.2m -1,152,876
14 FRANKLIN RESOURCES INC 0.06% of their portfolio San Mateo, CA 2,718,2902.7m $182.1m $182.1m 0.06% Reduced -848.7k -848,723
15 AMERIPRISE FINANCIAL INC 0.05% of their portfolio MINNEAPOLIS, MN 2,530,9942.5m $169.6m $169.6m 0.05% Reduced -204.3k -204,344
16 MONTANOVA CAPITAL, LLC 6.90% of their portfolio New York, NY 2,521,8002.5m $169.0m $169.0m 6.90% Added +498.8k +498,800
17 ALLIANCEBERNSTEIN L.P. 0.06% of their portfolio NASHVILLE, TN 2,492,2752.5m $167.0m $167.0m 0.06% Added +345.8k +345,796
18 Artisan Partners Limited Partnership 0.25% of their portfolio Milwaukee, WI 2,489,4312.5m $166.8m $166.8m 0.25% New
19 T. Rowe Price Investment Management, Inc. 0.10% of their portfolio BALTIMORE, MD 2,435,9622.4m $163.2m $163.2m 0.10% Reduced -1.0m -1,015,618
20 Palo Alto Investors LP 16.61% of their portfolio PALO ALTO, CA 2,138,9632.1m $143.3m $143.3m 16.61% Reduced -2.3m -2,284,406
21 JANUS HENDERSON GROUP PLC 0.08% of their portfolio LONDON, X0 2,091,7782.1m $140.1m $140.1m 0.08% Reduced -137.7k -137,685
22 Deep Track Capital, LP 4.00% of their portfolio GREENWICH, CT 2,000,0002.0m $134.0m $134.0m 4.00% Reduced -2.8m -2,783,679
23 Bank of New York Mellon Corp 0.02% of their portfolio NEW YORK, NY 1,807,3701.8m $121.1m $121.1m 0.02% Reduced -243.9k -243,941
24 NORGES BANK 0.02% of their portfolio OSLO, Q8 1,757,4251.8m $117.7m $117.7m 0.02% Added +168.9k +168,884
25 PRINCIPAL FINANCIAL GROUP INC 0.07% of their portfolio DES MOINES, IA 1,657,7601.7m $111.1m $111.1m 0.07% Added +218.5k +218,480
26 Clearbridge Investments, LLC 0.09% of their portfolio NEW YORK, NY 1,644,9481.6m $110.2m $110.2m 0.09% Added +714.5k +714,539
27 Integral Health Asset Management, LLC 10.34% of their portfolio New York, NY 1,550,0001.6m $103.8m $103.8m 10.34% Added +250.0k +250,000
28 FIL Ltd 0.10% of their portfolio HAMILTON, D0 1,518,1141.5m $101.7m $101.7m 0.10% Added +797.9k +797,869
29 Pictet Asset Management Holding SA 0.11% of their portfolio CAROUGE, V8 1,491,1351.5m $99.9m $99.9m 0.11% Reduced -38.9k -38,873
30 NORTHERN TRUST CORP 0.02% of their portfolio CHICAGO, IL 1,392,1071.4m $93.3m $93.3m 0.02% Added +55.3k +55,310
31 Nuveen Asset Management, LLC 0.03% of their portfolio CHICAGO, IL 1,329,9471.3m $89.1m $89.1m 0.03% Added +792.7k +792,716
32 ADAGE CAPITAL PARTNERS GP, L.L.C. 0.16% of their portfolio Boston, MA 1,325,0001.3m $88.8m $88.8m 0.16% Added +1.1m +1,075,000
33 Hood River Capital Management LLC 1.83% of their portfolio PALM BEACH GARDENS, FL 1,315,3921.3m $88.1m $88.1m 1.83% Added +352.9k +352,891
34 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.02% of their portfolio SAN FRANCISCO, CA 1,306,5961.3m $87.5m $87.5m 0.02% Added +179.8k +179,829
35 MARSHALL WACE, LLP 0.12% of their portfolio LONDON, X0 1,249,3511.2m $83.7m $83.7m 0.12% Reduced -80.7k -80,697
36 LOOMIS SAYLES & CO L P 0.11% of their portfolio BOSTON, MA 1,226,7261.2m $82.2m $82.2m 0.11% Reduced -265.1k -265,068
37 MILLENNIUM MANAGEMENT LLC 0.07% of their portfolio NEW YORK, NY 1,198,5101.2m $80.3m $80.3m 0.07% Added +921.9k +921,892
38 GOLDMAN SACHS GROUP INC 0.02% of their portfolio NEW YORK, NY 1,189,9011.2m $79.7m $79.7m 0.02% Added +436.3k +436,291
39 LORD, ABBETT & CO. LLC 0.13% of their portfolio JERSEY CITY, NJ 1,165,1541.2m $78.1m $78.1m 0.13% New
40 Eversept Partners, LP 5.93% of their portfolio NEW YORK, NY 1,155,5881.2m $77.4m $77.4m 5.93% New
41 BANK OF AMERICA CORP /DE/ 0.01% of their portfolio CHARLOTTE, NC 1,119,2081.1m $75.0m $75.0m 0.01% Added +123.1k +123,080
42 VIKING GLOBAL INVESTORS LP 0.27% of their portfolio STAMFORD, CT 1,035,9701.0m $69.4m $69.4m 0.27% New
43 Bellevue Group AG 1.11% of their portfolio ZURICH, V8 1,021,7001.0m $68.5m $68.5m 1.11% Reduced -1.1m -1,120,143
44 WELLINGTON MANAGEMENT GROUP LLP 0.01% of their portfolio Boston, MA 938,434938.4k $62.9m $62.9m 0.01% New
45 VOLORIDGE INVESTMENT MANAGEMENT, LLC 0.23% of their portfolio JUPITER, FL 922,002922.0k $61.8m $61.8m 0.23% Added +866.3k +866,276
46 Point72 Asset Management, L.P. 0.19% of their portfolio STAMFORD, CT 858,300858.3k $57.5m $57.5m 0.19% New
47 JANE STREET GROUP, LLC 0.06% of their portfolio NEW YORK, NY 840,000840.0k $56.3m $56.3m 0.06% Added +569.0k +569,027
48 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 822,804822.8k $55.1m $55.1m 0.00% Reduced -2.0m -1,996,005
49 Rock Springs Capital Management LP 1.63% of their portfolio Baltimore, MD 808,356808.4k $54.2m $54.2m 1.63% New
50 NOVO HOLDINGS A/S 2.89% of their portfolio HELLERUP, G7 800,000800.0k $53.6m $53.6m 2.89% Reduced -539.3k -539,304
51 CITADEL ADVISORS LLC 0.05% of their portfolio MIAMI, FL 799,746799.7k $53.6m $53.6m 0.05% Reduced -127.8k -127,817
52 FRONTIER CAPITAL MANAGEMENT CO LLC 0.51% of their portfolio Boston, MA 774,404774.4k $51.9m $51.9m 0.51% Added +27.1k +27,073
53 GW&K Investment Management, LLC 0.47% of their portfolio BOSTON, MA 761,732761.7k $51.0m $51.0m 0.47% Reduced -508.2k -508,166
54 Invesco Ltd. 0.01% of their portfolio ATLANTA, GA 756,241756.2k $50.7m $50.7m 0.01% Added +588.7k +588,678
55 AMERICAN CENTURY COMPANIES INC 0.03% of their portfolio KANSAS CITY, MO 755,271755.3k $50.6m $50.6m 0.03% Added +52.6k +52,647
56 Vestal Point Capital, LP 3.75% of their portfolio NEW YORK, NY 750,000750.0k $50.2m $50.2m 3.75% Unchanged
57 JENNISON ASSOCIATES LLC 0.03% of their portfolio NEW YORK, NY 744,280744.3k $49.9m $49.9m 0.03% Added +625.8k +625,768
58 VOYA INVESTMENT MANAGEMENT LLC 0.05% of their portfolio ATLANTA, GA 743,725743.7k $49.8m $49.8m 0.05% Added +271.7k +271,719
59 Long Focus Capital Management, LLC 5.13% of their portfolio SAN JUAN, PR 740,900740.9k $49.6m $49.6m 5.13% Added +309.3k +309,251
60 EVENTIDE ASSET MANAGEMENT, LLC 0.77% of their portfolio Boston, MA 675,185675.2k $45.2m $45.2m 0.77% Added +40.0k +40,000
61 Cormorant Asset Management, LP 2.63% of their portfolio BOSTON, MA 675,000675.0k $45.2m $45.2m 2.63% Added +100.0k +100,000
62 BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.11% of their portfolio Paris, I0 654,348654.3k $43.8m $43.8m 0.11% Reduced -318.0k -317,965
63 Octagon Capital Advisors LP 7.19% of their portfolio NEW YORK, NY 650,216650.2k $43.6m $43.6m 7.19% Reduced -489.8k -489,784
64 EMERALD ADVISERS, LLC 1.80% of their portfolio LEOLA, PA 640,267640.3k $42.9m $42.9m 1.80% Added +10.1k +10,088
65 KINGDON CAPITAL MANAGEMENT, L.L.C. 6.47% of their portfolio NEW YORK, NY 625,000625.0k $41.9m $41.9m 6.47% Added +170.0k +170,000
66 MPM BIOIMPACT LLC 6.41% of their portfolio BOSTON, MA 615,391615.4k $41.2m $41.2m 6.41% Added +84.6k +84,597
67 Fiera Capital Corp 0.13% of their portfolio MONTREAL, A8 605,527605.5k $40.6m $40.6m 0.13% New
68 FARALLON CAPITAL MANAGEMENT, L.L.C. 0.22% of their portfolio SAN FRANCISCO, CA 568,000568.0k $38.1m $38.1m 0.22% Not comparable
69 Candriam S.C.A. 0.23% of their portfolio STRASSEN, N4 555,934555.9k $37.2m $37.2m 0.23% Added +165.7k +165,734
70 First Light Asset Management, LLC 3.24% of their portfolio Edina, MN 551,303551.3k $36.9m $36.9m 3.24% Added +268.5k +268,537
71 TD Asset Management Inc 0.03% of their portfolio Toronto, A6 525,682525.7k $35.2m $35.2m 0.03% Added +98.5k +98,504
72 Eagle Health Investments LP 6.15% of their portfolio Greenwich, CT 513,700513.7k $34.4m $34.4m 6.15% New
73 FRED ALGER MANAGEMENT, LLC 0.16% of their portfolio NEW YORK, NY 498,572498.6k $33.4m $33.4m 0.16% New
74 EMERALD MUTUAL FUND ADVISERS TRUST 1.73% of their portfolio LEOLA, PA 493,849493.8k $33.1m $33.1m 1.73% Added +9.1k +9,135
75 SOROS FUND MANAGEMENT LLC 0.71% of their portfolio NEW YORK, NY 470,700470.7k $31.5m $31.5m 0.71% New
76 Hudson Bay Capital Management LP 0.24% of their portfolio STAMFORD, CT 467,500467.5k $31.3m $31.3m 0.24% Reduced -159.3k -159,310
77 AXA S.A. 0.05% of their portfolio PARIS, I0 454,236454.2k $30.4m $30.4m 0.05% Added +165.6k +165,637
78 UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.01% of their portfolio NEW YORK, NY 437,255437.3k $29.3m $29.3m 0.01% Added +30.2k +30,230
79 Avidity Partners Management LP 1.22% of their portfolio DALLAS, TX 430,000430.0k $28.8m $28.8m 1.22% New
80 Alyeska Investment Group, L.P. 0.17% of their portfolio CHICAGO, IL 428,804428.8k $28.7m $28.7m 0.17% Added +228.8k +228,804
81 Iron Triangle Partners LP 2.90% of their portfolio Cos Cob, CT 413,196413.2k $27.7m $27.7m 2.90% New
82 Assenagon Asset Management S.A. 0.07% of their portfolio SENNINGERBERG, N4 391,054391.1k $26.2m $26.2m 0.07% Reduced -820.5k -820,506
83 SAMLYN CAPITAL, LLC 0.41% of their portfolio New York, NY 359,254359.3k $24.1m $24.1m 0.41% Reduced -228.4k -228,380
84 Ensign Peak Advisors, Inc 0.04% of their portfolio SALT LAKE CITY, UT 359,029359.0k $24.1m $24.1m 0.04% Added +17.5k +17,455
85 PANAGORA ASSET MANAGEMENT INC 0.12% of their portfolio BOSTON, MA 356,135356.1k $23.9m $23.9m 0.12% Reduced -158.7k -158,694
86 C WorldWide Group Holding A/S 0.25% of their portfolio COPENHAGEN, G7 343,110343.1k $23.0m $23.0m 0.25% Unchanged
87 Allspring Global Investments Holdings, LLC 0.04% of their portfolio CHARLOTTE, NC 328,073328.1k $22.0m $22.0m 0.04% Added +323.8k +323,772
88 First Turn Management, LLC 3.52% of their portfolio DEL MAR, CA 323,360323.4k $21.7m $21.7m 3.52% New
89 NEW YORK STATE COMMON RETIREMENT FUND 0.03% of their portfolio ALBANY, NY 322,299322.3k $21.6m $21.6m 0.03% Added +267.1k +267,090
90 Tri Locum Partners LP 5.36% of their portfolio NEW YORK, NY 316,501316.5k $21.2m $21.2m 5.36% New
91 EAGLE ASSET MANAGEMENT INC 0.11% of their portfolio ST PETERSBURG, FL 314,690314.7k $20.9m $20.9m 0.11% Reduced -209.7k -209,682
92 TWO SIGMA ADVISERS, LP 0.04% of their portfolio NEW YORK, NY 295,400295.4k $19.8m $19.8m 0.04% Reduced -421.0k -421,000
93 D. E. Shaw & Co., Inc. 0.03% of their portfolio New York, NY 288,551288.6k $19.3m $19.3m 0.03% Added +114.5k +114,529
94 MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.02% of their portfolio Toronto, A6 283,011283.0k $19.0m $19.0m 0.02% Added +50.3k +50,330
95 SEI INVESTMENTS CO 0.03% of their portfolio OAKS, PA 277,712277.7k $18.6m $18.6m 0.03% Added +196.6k +196,639
96 Swiss National Bank 0.01% of their portfolio ZURICH, V8 277,500277.5k $18.6m $18.6m 0.01% Added +9.1k +9,100
97 SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC 0.84% of their portfolio Boston, MA 271,535271.5k $18.2m $18.2m 0.84% New
98 SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC 0.42% of their portfolio BALA CYNWYD, PA 270,960271.0k $18.2m $18.2m 0.42% Added +104.6k +104,551
99 Granahan Investment Management, LLC 0.69% of their portfolio WALTHAM, MA 259,275259.3k $17.4m $17.4m 0.69% Added +125.5k +125,520
100 DEUTSCHE BANK AG\ 0.01% of their portfolio FRANKFURT AM MAIN, 2M 255,989256.0k $17.2m $17.2m 0.01% Added +1.4k +1,429