INCYTE CORP INCY
COM · Common Stock · CUSIP 45337C102 · ISIN US45337C1027
American pharmaceutical company
- SectorHealth care
- IndustryServices-Commercial Physical & Biological Research
- HeadquartersWilmington, DE
- Founded2001
- Websiteincyte.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($40.9m this quarter). Holder counts are more reliable. Shares outstanding: 192.6m as of 2024-07-23, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $60.58. Options: 18 managers hold calls ($51.7m notional), 18 hold puts ($42.3m).
Trends to Q2 2024
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 537 |
| Q4 2022 | 558 |
| Q1 2023 | 552 |
| Q2 2023 | 529 |
| Q3 2023 | 531 |
| Q4 2023 | 558 |
| Q1 2024 | 587 |
| Q2 2024 | 586 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 265 | 251 |
| Q1 2023 | 313 | 230 |
| Q2 2023 | 238 | 287 |
| Q3 2023 | 298 | 212 |
| Q4 2023 | 268 | 257 |
| Q1 2024 | 295 | 255 |
| Q2 2024 | 292 | 288 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2023 | $30.5m | $26.3m | 0.86 |
| Q4 2023 | $57.8m | $27.6m | 0.48 |
| Q1 2024 | $23.6m | $37.9m | 1.61 |
| Q2 2024 | $51.7m | $42.3m | 0.82 |
Biggest buyers
| Pacer Advisors, Inc. | Added | +2.7m |
| JANE STREET GROUP, LLC | Added | +1.3m |
| AQR CAPITAL MANAGEMENT LLC | Added | +1.1m |
| STATE STREET CORP | Added | +952.0k |
| Squarepoint Ops LLC | Added | +880.6k |
| GLENMEDE TRUST CO NA | New | +854.0k |
| ACADIAN ASSET MANAGEMENT LLC | Added | +779.2k |
| Invesco Ltd. | Added | +751.3k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | Added | +611.7k |
| Avidity Partners Management LP | New | +529.0k |
Biggest sellers
| MORGAN STANLEY | Reduced | -6.5m |
| BAKER BROS. ADVISORS LP | Reduced | -5.4m |
| JACOBS LEVY EQUITY MANAGEMENT, INC | Reduced | -2.4m |
| VANGUARD GROUP INC | Reduced | -2.3m |
| Amundi | Reduced | -2.1m |
| BlackRock Inc. | Reduced | -1.9m |
| Sofinnova Investments, Inc. | Sold out | -1.3m |
| Man Group plc | Reduced | -1.3m |
| TWO SIGMA ADVISERS, LP | Reduced | -1.2m |
| LOS ANGELES CAPITAL MANAGEMENT LLC | Reduced | -1.2m |
Biggest calls
| LMR Partners LLP | New | $9.9m163.4k shares |
| J. Goldman & Co LP | New | $9.1m150.4k shares |
| Caption Management, LLC | New | $6.4m105.0k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $5.8m95.6k shares |
| CITADEL ADVISORS LLC | Reduced | $4.2m70.0k shares |
| BARCLAYS PLC | Added | $3.6m60.0k shares |
| GOLDMAN SACHS GROUP INC | Added | $3.4m56.9k shares |
| JANE STREET GROUP, LLC | Added | $2.7m44.9k shares |
| SIMPLEX TRADING, LLC | Reduced | $2.0m33.7k shares |
| GROUP ONE TRADING LLC | Added | $1.2m20.2k shares |
Biggest puts
| CITADEL ADVISORS LLC | Added | $10.1m166.3k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $8.3m136.9k shares |
| SIMPLEX TRADING, LLC | Added | $5.8m95.7k shares |
| JANE STREET GROUP, LLC | Reduced | $4.6m76.7k shares |
| Caption Management, LLC | New | $1.8m30.0k shares |
| GOLDMAN SACHS GROUP INC | New | $1.6m26.9k shares |
| WOLVERINE TRADING, LLC | Added | $1.6m25.9k shares |
| IMC-Chicago, LLC | Reduced | $1.5m25.4k shares |
| GROUP ONE TRADING LLC | Added | $1.5m24.6k shares |
| CAPITAL FUND MANAGEMENT S.A. | Reduced | $1.2m20.4k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
BAKER BROS. ADVISORS LP
13D · may seek influence
-0.1 pts · filed 2026-05-11
Stated purposeItem 4 of Schedule 13D is supplemented and superseded, as the case may be, as follows: On May 8, 2026 the Adviser acquired beneficial ownership of 15,000 shares of common stock ("Common Stock") of Incyte Corporation (the "Issuer"), as a result of the exercise of 15,000 options to purchase Common Stock at $84.53 per share (the "Exercised Stock Options") held directly by Julian C. Baker. Julian C. Baker currently serves on the Issuer's board of directors (the "Board") as a representative of the Funds. The policy of the Funds and the Adviser does not permit managing members of the Adviser GP or full-time employees of the Adviser to receive compensation for serving as directors of the Issuer, and the Funds are instead entitled to the pecuniary interest in the Exercised Stock Options. Julian C… Full filing |
15.6% |
| BlackRock, Inc. 13G · institution filed 2025-10-17 | 7.8% |
| VANGUARD CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-04-30 | 6.3% |
| DODGE & COX 13G · institution filed 2026-05-14 | 6.2% |
Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-27; now reported by VANGUARD CAPITAL MANAGEMENT LLC)
Insider purchases and sales in Q2 2024
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q3 2022 | 0 | — | 3 | $817.4k | — |
| Q4 2022 | 0 | — | 2 | $1.5m | — |
| Q1 2023 | 0 | — | 4 | $8.2m | — |
| Q2 2023 | 0 | — | 0 | — | — |
| Q3 2023 | 0 | — | 2 | $1.9m | $1.4m |
| Q4 2023 | 0 | — | 1 | $78.6k | $78.6k |
| Q1 2024 | 0 | — | 2 | $525.2k | $525.2k |
| Q2 2024 | 0 | — | 2 | $1.2m | $1.2m |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2024-06-12 | Flannelly Barry P EVP & General Manager US | Sold plan | $1.1m19.2k shares |
| 2024-06-06 | Tray Thomas Principal Accounting Officer | Sold plan | $64.4k1.1k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2024
| Manager | Shares | Change |
|---|---|---|
| BAKER BROS. ADVISORS LP 23.81% of their portfolio | 30.7m $1.9bn | Reduced -5.4m |
| BlackRock Inc. 0.03% of their portfolio | 21.4m $1.3bn | Reduced -1.9m |
| VANGUARD GROUP INC 0.02% of their portfolio | 20.4m $1.2bn | Reduced -2.3m |
| Dodge & Cox 0.56% of their portfolio | 15.3m $926.2m | Reduced -136.7k |
| STATE STREET CORP 0.03% of their portfolio | 10.9m $657.8m | Added +952.0k |
| RENAISSANCE TECHNOLOGIES LLC 0.54% of their portfolio | 5.2m $316.3m | Reduced -458.1k |
| GEODE CAPITAL MANAGEMENT, LLC 0.02% of their portfolio | 4.0m $244.6m | Reduced -393.3k |
| Invesco Ltd. 0.05% of their portfolio | 3.6m $216.4m | Added +751.3k |
| ACADIAN ASSET MANAGEMENT LLC 0.66% of their portfolio | 3.6m $215.8m | Added +779.2k |
| LSV ASSET MANAGEMENT 0.37% of their portfolio | 2.8m $167.9m | Added +15.1k |
| Pacer Advisors, Inc. 0.37% of their portfolio | 2.7m $163.2m | Added +2.7m |
| AQR CAPITAL MANAGEMENT LLC 0.25% of their portfolio | 2.7m $159.9m | Added +1.1m |
| MORGAN STANLEY 0.01% of their portfolio | 2.3m $136.7m | Reduced -6.5m |
| Bellevue Group AG 2.12% of their portfolio | 2.2m $130.5m | Added +116 |
| NORGES BANK 0.02% of their portfolio | 2.1m $128.8m | Added +72.1k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.03% of their portfolio | 1.8m $110.2m | Added +611.7k |
| NORTHERN TRUST CORP 0.02% of their portfolio | 1.8m $109.9m | Reduced -37.8k |
| FMR LLC 0.01% of their portfolio | 1.8m $108.4m | Added +163.5k |
| ARMISTICE CAPITAL, LLC 2.80% of their portfolio | 1.8m $106.9m | Reduced -423.2k |
| KBC Group NV 0.32% of their portfolio | 1.7m $104.5m | Added +185.5k |
| Legal & General Group Plc 0.03% of their portfolio | 1.5m $93.3m | Reduced -147.4k |
| JANE STREET GROUP, LLC 0.10% of their portfolio | 1.5m $90.3m | Added +1.3m |
| Squarepoint Ops LLC 0.30% of their portfolio | 1.3m $81.5m | Added +880.6k |
| Candriam S.C.A. 0.48% of their portfolio | 1.3m $80.0m | Reduced -154.1k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.01% of their portfolio | 1.2m $75.5m | Reduced -79.9k |
| FIRST TRUST ADVISORS LP 0.08% of their portfolio | 1.2m $75.4m | Added +350.0k |
| HSBC HOLDINGS PLC 0.05% of their portfolio | 1.2m $75.2m | Added +65.3k |
| D. E. Shaw & Co., Inc. 0.10% of their portfolio | 1.2m $74.8m | Reduced -152.4k |
| Robeco Institutional Asset Management B.V. 0.16% of their portfolio | 1.2m $72.5m | Added +43.7k |
| DIMENSIONAL FUND ADVISORS LP 0.02% of their portfolio | 1.2m $71.6m | Added +230.7k |
| Woodline Partners LP 0.67% of their portfolio | 1.2m $70.0m | Added +20.7k |
| Bank of New York Mellon Corp 0.01% of their portfolio | 1.1m $69.6m | Reduced -64.3k |
| Connor, Clark & Lunn Investment Management Ltd. 0.29% of their portfolio | 1.1m $68.5m | Reduced -57.4k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 988.4k $59.9m | Added +107.3k |
| GOLDMAN SACHS GROUP INC 0.01% of their portfolio | 948.7k $57.5m | Added +223.9k |
| California Public Employees Retirement System 0.04% of their portfolio | 908.6k $55.1m | Reduced -200.7k |
| BARCLAYS PLC 0.02% of their portfolio | 894.4k $54.2m | Added +401.0k |
| Allspring Global Investments Holdings, LLC 0.09% of their portfolio | 892.7k $54.1m | Added +490.7k |
| FEDERATED HERMES, INC. 0.12% of their portfolio | 858.1k $52.0m | Reduced -77.2k |
| GLENMEDE TRUST CO NA 0.26% of their portfolio | 854.0k $51.8m | New |
| CITADEL ADVISORS LLC 0.05% of their portfolio | 821.7k $49.8m | Added +524.4k |
| DEUTSCHE BANK AG\ 0.02% of their portfolio | 798.0k $48.4m | Reduced -246.5k |
| Man Group plc 0.13% of their portfolio | 786.6k $47.7m | Reduced -1.3m |
| APG Asset Management N.V. 0.08% of their portfolio | 783.3k $44.3m | Reduced -380.4k |
| AMERIPRISE FINANCIAL INC 0.01% of their portfolio | 767.1k $46.5m | Reduced -89.5k |
| Pictet Asset Management Holding SA 0.05% of their portfolio | 752.7k $45.6m | Reduced -957.3k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 718.7k $43.6m | Added +80.2k |
| Amundi 0.02% of their portfolio | 699.7k $40.3m | Reduced -2.1m |
| Swedbank AB 0.05% of their portfolio | 666.2k $40.4m | Added +9.0k |
| CANADA PENSION PLAN INVESTMENT BOARD 0.04% of their portfolio | 645.9k $39.2m | Added +225.5k |
| Russell Investments Group, Ltd. 0.06% of their portfolio | 625.9k $38.0m | Reduced -407.7k |
| Schonfeld Strategic Advisors LLC 0.29% of their portfolio | 624.5k $37.9m | Reduced -5.3k |
| Grantham, Mayo, Van Otterloo & Co. LLC 0.12% of their portfolio | 585.7k $35.5m | Added +60.9k |
| Sumitomo Mitsui Trust Group, Inc. 0.02% of their portfolio | 533.2k $32.3m | Reduced -92.3k |
| Avidity Partners Management LP 1.36% of their portfolio | 529.0k $32.1m | New |
| Applied Finance Capital Management, LLC 1.40% of their portfolio | 499.8k $30.3m | Added +201.4k |
| Swiss National Bank 0.02% of their portfolio | 478.8k $29.0m | Reduced -91.7k |
| HRT FINANCIAL LP 0.16% of their portfolio | 473.3k $28.7m | Added +289.6k |
| Nuveen Asset Management, LLC 0.01% of their portfolio | 461.7k $28.0m | Reduced -28.6k |
| UBS Group AG 0.01% of their portfolio | 450.9k $27.3m | Added +46.7k |
| MILLENNIUM MANAGEMENT LLC 0.02% of their portfolio | 420.3k $25.5m | Reduced -414.7k |
| WORLDQUANT MILLENNIUM ADVISORS LLC 0.23% of their portfolio | 408.1k $24.7m | Reduced -152.0k |
| ARK Investment Management LLC 0.21% of their portfolio | 398.7k $24.2m | Reduced -40.0k |
| Capital World Investors 0.00% of their portfolio | 396.0k $24.0m | Unchanged |
| TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY 0.21% of their portfolio | 394.6k $23.9m | Added +379.4k |
| MACKENZIE FINANCIAL CORP 0.03% of their portfolio | 381.7k $23.1m | Reduced -12.1k |
| TODD ASSET MANAGEMENT LLC 0.48% of their portfolio | 380.8k $23.1m | New |
| AXA S.A. 0.03% of their portfolio | 377.7k $22.9m | Added +196.8k |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC 0.08% of their portfolio | 374.0k $22.7m | Reduced -673.9k |
| Ensign Peak Advisors, Inc 0.04% of their portfolio | 371.3k $22.5m | Added +154.7k |
| LOS ANGELES CAPITAL MANAGEMENT LLC 0.08% of their portfolio | 370.4k $22.5m | Reduced -1.2m |
| RHUMBLINE ADVISERS 0.02% of their portfolio | 363.2k $22.0m | Reduced -23.2k |
| Caisse de depot et placement du Quebec 0.05% of their portfolio | 334.8k $20.3m | Added +319.0k |
| ALLIANCEBERNSTEIN L.P. 0.01% of their portfolio | 314.8k $19.1m | Added +22.0k |
| Rafferty Asset Management, LLC 0.07% of their portfolio | 303.1k $18.4m | Added +131.1k |
| CITIGROUP INC 0.02% of their portfolio | 291.2k $17.7m | Reduced -135.1k |
| FRANKLIN RESOURCES INC 0.00% of their portfolio | 251.9k $15.3m | Reduced -6.7k |
| VICTORY CAPITAL MANAGEMENT INC 0.02% of their portfolio | 251.8k $15.3m | Added +64.5k |
| PRINCIPAL FINANCIAL GROUP INC 0.01% of their portfolio | 247.9k $15.0m | Reduced -5.5k |
| Andra AP-fonden 0.25% of their portfolio | 247.8k $15.0m | Added +64.5k |
| Mitsubishi UFJ Asset Management Co., Ltd. 0.02% of their portfolio | 247.2k $15.0m | Added +23.1k |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main 0.02% of their portfolio | 246.6k $14.9m | Added +87.1k |
| ASHFORD CAPITAL MANAGEMENT INC 2.00% of their portfolio | 244.8k $14.8m | Reduced -104.1k |
| AMERICAN CENTURY COMPANIES INC 0.01% of their portfolio | 240.6k $14.6m | Reduced -5.1k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.02% of their portfolio | 239.1k $14.5m | Reduced -66.4k |
| CAPITAL FUND MANAGEMENT S.A. 0.16% of their portfolio | 234.8k $14.2m | Added +81.1k |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 0.03% of their portfolio | 225.4k $13.7m | Reduced -13.7k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 225.1k $13.6m | Reduced -418.5k |
| Qube Research & Technologies Ltd 0.02% of their portfolio | 221.8k $13.4m | Reduced -1.0m |
| Hudson Bay Capital Management LP 0.10% of their portfolio | 219.3k $13.3m | Reduced -81.1k |
| TWO SIGMA INVESTMENTS, LP 0.03% of their portfolio | 218.1k $13.2m | Reduced -836.4k |
| BANK OF MONTREAL /CAN/ 0.00% of their portfolio | 217.9k $13.8m | Reduced -434.9k |
| Mitsubishi UFJ Trust & Banking Corp 0.03% of their portfolio | 214.2k $13.0m | Reduced -80.3k |
| NEW YORK STATE TEACHERS RETIREMENT SYSTEM 0.03% of their portfolio | 212.0k $12.8m | Added +8.3k |
| Illinois Municipal Retirement Fund 0.19% of their portfolio | 210.4k $12.8m | Reduced -71 |
| HighTower Advisors, LLC 0.02% of their portfolio | 210.4k $12.7m | Added +11.9k |
| Skandinaviska Enskilda Banken AB (publ) 0.06% of their portfolio | 204.9k $12.4m | Added +13.7k |
| SECTOR GAMMA AS 4.61% of their portfolio | 203.4k $12.3m | Reduced -61.5k |
| BNP PARIBAS FINANCIAL MARKETS 0.01% of their portfolio | 200.5k $12.2m | Reduced -27.7k |
| GRIMES & Co WEALTH MANAGEMENT, LLC 0.35% of their portfolio | 192.3k $11.7m | Added +7.2k |