IMMUNOCORE HLDGS PLC IMCR
ADS · ADR · CUSIP 45258D105 · ISIN US45258D1054
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersPhiladelphia, United Kingdom
- Founded2008
- Websiteimmunocore.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($373.8k this quarter). Holder counts are more reliable. Implied quarter-end price ≈ $57.07. Options: 7 managers hold calls ($10.3m notional), 8 hold puts ($6.1m).
Trends to Q4 2022
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 86 |
| Q4 2022 | 105 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2022 | $1.4m | $9.9m | 7.11 |
| Q4 2022 | $10.3m | $6.1m | 0.60 |
Biggest buyers
| WELLINGTON MANAGEMENT GROUP LLP | Added | +1.5m |
| RTW INVESTMENTS, LP | Added | +1.1m |
| PICTET ASSET MANAGEMENT SA | New | +618.3k |
| FMR LLC | Added | +610.7k |
| BlackRock Inc. | Added | +289.6k |
| D. E. Shaw & Co., Inc. | Added | +230.9k |
| RENAISSANCE TECHNOLOGIES LLC | Added | +210.3k |
| MORGAN STANLEY | Added | +205.0k |
| MILLENNIUM MANAGEMENT LLC | Added | +181.5k |
| PRICE T ROWE ASSOCIATES INC /MD/ | Added | +170.4k |
Biggest sellers
| Avidity Partners Management LP | Reduced | -925.1k |
| COWEN AND COMPANY, LLC | Reduced | -606.5k |
| Rathbones Group PLC | Sold out | -190.0k |
| FIRST MANHATTAN CO. LLC. | Reduced | -182.1k |
| Rock Springs Capital Management LP | Reduced | -172.7k |
| SCHRODER INVESTMENT MANAGEMENT GROUP | Reduced | -114.8k |
| CITADEL ADVISORS LLC | Reduced | -94.8k |
| Venrock Adviser, LLC | Sold out | -94.6k |
| Velan Capital Investment Management LP | Reduced | -87.4k |
| GREAT POINT PARTNERS LLC | Sold out | -78.5k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $4.9m86.0k shares |
| MILLENNIUM MANAGEMENT LLC | New | $3.3m58.0k shares |
| UBS Group AG | New | $736.2k12.9k shares |
| CITADEL ADVISORS LLC | Added | $639.2k11.2k shares |
| GROUP ONE TRADING LLC | New | $604.9k10.6k shares |
| SIMPLEX TRADING, LLC | Added | $68.0k1.2k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $2.1m36.8k shares |
| JANE STREET GROUP, LLC | Reduced | $1.7m29.7k shares |
| Caption Management, LLC | New | $1.6m27.5k shares |
| CITADEL ADVISORS LLC | Reduced | $348.1k6.1k shares |
| UBS Group AG | Unchanged | $239.7k4.2k shares |
| GROUP ONE TRADING LLC | New | $119.8k2.1k shares |
| SIMPLEX TRADING, LLC | Reduced | $51.0k900 shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| WELLINGTON MANAGEMENT GROUP LLP 13G · institution +1.4 pts · filed 2026-08-13 | 11.6% |
| Jallal Bahija 13G · exempt (held before listing) new · filed 2025-02-14 | 8.2% |
| PRIMECAP MANAGEMENT CO/CA/ 13G · institution +2.2 pts · filed 2025-08-14 | 7.5% |
| Bellevue Group AG 13G · institution new · filed 2025-11-14 | 5.6% |
| TANG CAPITAL MANAGEMENT LLC 13G · passive investor new · filed 2025-10-24 | 5.2% |
Fell to 5% or below in the last year: FMR LLC (3.6%, 2026-10-07), Vestal Point Capital, LP (3.5%, 2026-08-14), T. Rowe Price Investment Management, Inc. (3.7%, 2026-05-15)
Insider purchases and sales in Q4 2022
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
None reported in Q4 2022.
Holders, Q4 2022
| Manager | Shares | Change |
|---|---|---|
| RTW INVESTMENTS, LP 6.48% of their portfolio | 5.6m $317.3m | Added +1.1m |
| Rock Springs Capital Management LP 4.56% of their portfolio | 3.3m $189.5m | Reduced -172.7k |
| BAKER BROS. ADVISORS LP 0.86% of their portfolio | 2.5m $143.9m | Unchanged |
| WELLINGTON MANAGEMENT GROUP LLP 0.02% of their portfolio | 2.2m $122.9m | Added +1.5m |
| FMR LLC 0.01% of their portfolio | 2.0m $114.4m | Added +610.7k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.01% of their portfolio | 1.3m $76.1m | Added +170.4k |
| Avidity Partners Management LP 1.54% of their portfolio | 1.2m $65.9m | Reduced -925.1k |
| GENERAL ATLANTIC, L.P. 0.72% of their portfolio | 950.0k $54.2m | Unchanged |
| Paradigm Biocapital Advisors LP 5.75% of their portfolio | 857.9k $49.0m | Added +84.8k |
| BlackRock Inc. 0.00% of their portfolio | 789.0k $45.0m | Added +289.6k |
| PICTET ASSET MANAGEMENT SA 0.05% of their portfolio | 618.3k $35.3m | New |
| FIRST MANHATTAN CO. LLC. 0.13% of their portfolio | 613.7k $35.0m | Reduced -182.1k |
| Holocene Advisors, LP 0.21% of their portfolio | 598.7k $34.2m | Added +97.6k |
| Bill & Melinda Gates Foundation 25.37% of their portfolio | 576.9k $32.9m | Unchanged |
| PRINCIPAL FINANCIAL GROUP INC 0.02% of their portfolio | 502.0k $28.6m | Reduced -24.3k |
| Logos Global Management LP 3.34% of their portfolio | 500.0k $28.5m | Added +150.0k |
| TANG CAPITAL MANAGEMENT LLC 3.36% of their portfolio | 405.6k $23.1m | Unchanged |
| COWEN AND COMPANY, LLC 2.45% of their portfolio | 405.2k $23.1m | Reduced -606.5k |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ 0.01% of their portfolio | 365.9k $20.9m | Added +1.2k |
| D. E. Shaw & Co., Inc. 0.04% of their portfolio | 363.4k $20.7m | Added +230.9k |
| MORGAN STANLEY 0.00% of their portfolio | 354.7k $20.2m | Added +205.0k |
| MILLENNIUM MANAGEMENT LLC 0.02% of their portfolio | 337.7k $19.3m | Added +181.5k |
| ARMISTICE CAPITAL, LLC 0.52% of their portfolio | 336.0k $19.2m | Added +20.0k |
| RENAISSANCE TECHNOLOGIES LLC 0.02% of their portfolio | 305.1k $17.4m | Added +210.3k |
| ACADIAN ASSET MANAGEMENT LLC 0.08% of their portfolio | 269.9k $15.4m | Added +85.4k |
| Thrivent Financial for Lutherans 0.03% of their portfolio | 213.8k $12.2m | Added +3.9k |
| Velan Capital Investment Management LP 12.50% of their portfolio | 206.0k $11.8m | Reduced -87.4k |
| CITADEL ADVISORS LLC 0.01% of their portfolio | 199.6k $11.4m | Reduced -94.8k |
| BARCLAYS PLC 0.01% of their portfolio | 197.1k $11.3m | First filing |
| SCHRODER INVESTMENT MANAGEMENT GROUP 0.02% of their portfolio | 165.6k $9.4m | Reduced -114.8k |
| Qube Research & Technologies Ltd 0.06% of their portfolio | 165.5k $9.4m | New |
| Rhenman & Partners Asset Management AB 0.89% of their portfolio | 150.0k $8.6m | Unchanged |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC 0.05% of their portfolio | 144.7k $8.3m | Added +81.7k |
| Candriam S.C.A. 0.05% of their portfolio | 119.1k $6.8m | Reduced -247 |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 113.5k $6.5m | Added +101.3k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 112.9k $6.4m | Added +34.4k |
| Allspring Global Investments Holdings, LLC 0.01% of their portfolio | 94.9k $5.4m | Reduced -752 |
| TD Asset Management Inc 0.01% of their portfolio | 92.9k $5.3m | Added +12.5k |
| Cubist Systematic Strategies, LLC 0.04% of their portfolio | 84.0k $4.8m | Added +33.3k |
| SAMSARA BIOCAPITAL, LLC 0.99% of their portfolio | 81.0k $4.6m | Unchanged |
| TWO SIGMA INVESTMENTS, LP 0.01% of their portfolio | 71.4k $4.1m | New |
| Pier Capital, LLC 0.64% of their portfolio | 68.7k $3.9m | Reduced -973 |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 63.5k $3.7m | Added +5.1k |
| CWM, LLC 0.03% of their portfolio | 60.4k $3.5m | Reduced -10.2k |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND 0.01% of their portfolio | 45.2k $2.6m | Reduced -27.2k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 43.3k $2.5m | New |
| STATE STREET CORP 0.00% of their portfolio | 36.2k $2.1m | Added +27.3k |
| Jump Financial, LLC 0.10% of their portfolio | 33.5k $1.9m | Reduced -7.6k |
| PUTNAM INVESTMENTS LLC 0.00% of their portfolio | 32.8k $1.9m | New |
| Eschler Asset Management LLP 3.46% of their portfolio | 32.0k $1.8m | Added +12.0k |
| ALPS ADVISORS INC 0.02% of their portfolio | 30.7k $1.8m | Added +6.7k |
| MARSHALL WACE, LLP 0.00% of their portfolio | 30.4k $1.7m | Added +6.3k |
| Robertson Stephens Wealth Management, LLC 0.13% of their portfolio | 22.7k $1.3m | Unchanged |
| ADVISORY RESEARCH INC 0.11% of their portfolio | 21.4k $1.2m | Reduced -5.8k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 21.3k $1.2m | Reduced -21.2k |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 21.1k $1.2m | Added +700 |
| Trexquant Investment LP 0.03% of their portfolio | 16.3k $927.5k | New |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 14.9k $849.4k | Reduced -35.8k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 14.5k $825.0k | Reduced -2.0k |
| FIRST TRUST ADVISORS LP 0.00% of their portfolio | 14.0k $797.7k | New |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 13.7k $780.1k | New |
| Squarepoint Ops LLC 0.01% of their portfolio | 13.3k $761.0k | Added +7.7k |
| HighVista Strategies LLC 0.45% of their portfolio | 13.2k $753.0k | Reduced -3.4k |
| Vident Investment Advisory, LLC 0.03% of their portfolio | 12.8k $729.4k | Reduced -8.2k |
| Robeco Institutional Asset Management B.V. 0.00% of their portfolio | 12.7k $723.4k | New |
| SEI INVESTMENTS CO 0.00% of their portfolio | 12.5k $711.3k | Reduced -16.3k |
| Caption Management, LLC 0.12% of their portfolio | 12.0k $684.8k | New |
| COMMONWEALTH OF PENNSYLVANIA PUBLIC SCHOOL EMPLS RETRMT SYS 0.01% of their portfolio | 12.0k $683.0k | New |
| Tidal Investments LLC 0.03% of their portfolio | 11.8k $675.0k | New |
| Dalton Investments, Inc. 0.49% of their portfolio | 10.0k $570.7k | Unchanged |
| FRED ALGER MANAGEMENT, LLC 0.00% of their portfolio | 8.4k $477.0k | Added +382 |
| Quantbot Technologies LP 0.03% of their portfolio | 7.4k $422.3k | Added +3.2k |
| UBS Group AG 0.00% of their portfolio | 6.5k $373.8k | Added +627 |
| OPPENHEIMER & CO INC 0.01% of their portfolio | 6.4k $364.4k | New |
| SG Americas Securities, LLC 0.01% of their portfolio | 6.3k $357.0k | New |
| Legal & General Group Plc 0.00% of their portfolio | 5.8k $328.2k | Reduced -9.6k |
| Aigen Investment Management, LP 0.05% of their portfolio | 5.6k $318.1k | New |
| OVERSEA-CHINESE BANKING Corp Ltd 0.02% of their portfolio | 5.4k $308.0k | First filing |
| VIRTUS ADVISERS, LLC 0.15% of their portfolio | 5.1k $292.8k | Reduced -3.5k |
| ENVESTNET ASSET MANAGEMENT INC 0.00% of their portfolio | 5.1k $292.5k | New |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP 0.00% of their portfolio | 4.7k $269.0k | New |
| Capital CS Group, LLC 0.28% of their portfolio | 4.4k $252.4k | New |
| Cetera Investment Advisers 0.00% of their portfolio | 4.0k $230.8k | New |
| BROWN ADVISORY INC 0.00% of their portfolio | 4.0k $228.3k | New |
| Verition Fund Management LLC 0.00% of their portfolio | 4.0k $228.1k | New |
| JTC Employer Solutions Trustee Ltd 0.02% of their portfolio | 3.9k $223.0k | New |
| Tower Research Capital LLC (TRC) 0.01% of their portfolio | 2.2k $128.0k | Reduced -904 |
| Kapitalo Investimentos Ltda 0.09% of their portfolio | 2.0k $114.1k | New |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 827 $47.2k | Added +391 |
| OSAIC HOLDINGS, INC. 0.00% of their portfolio | 729 $41.0k | Added +11 |
| ASSETMARK, INC 0.00% of their portfolio | 608 $34.7k | Added +297 |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 581 $33.2k | Reduced -592 |
| Navera Investment Management Ltd. 0.00% of their portfolio | 575 $32.8k | Unchanged |
| CITIGROUP INC 0.00% of their portfolio | 346 $19.7k | New |
| China Universal Asset Management Co., Ltd. 0.01% of their portfolio | 262 $15.0k | New |
| Beacon Capital Management, LLC 0.00% of their portfolio | 250 $14.3k | Unchanged |
| Daiwa Securities Group Inc. 0.00% of their portfolio | 104 $6.0k | New |
| IFP Advisors, Inc 0.00% of their portfolio | 100 $4.0k | New |
| Steward Partners Investment Advisory, LLC 0.00% of their portfolio | 100 $5.7k | New |
| Belpointe Asset Management LLC 0.00% of their portfolio | 50 $2.9k | New |