HEMAB THERAPEUTICS HLDGS INC COAG
COM SHS · Common Stock · CUSIP 423494103
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersCambridge, MA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Shares outstanding: 46.7m as of 2026-07-31, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $36.73.
Biggest buyers
| RA CAPITAL MANAGEMENT, L.P. | New | +7.8m |
| NOVO HOLDINGS A/S | New | +4.2m |
| FMR LLC | New | +3.7m |
| Capital International Investors | New | +3.6m |
| Deep Track Capital, LP | New | +3.6m |
| Siren, L.L.C. | New | +2.1m |
| Avoro Capital Advisors LLC | New | +1.9m |
| Bain Capital Life Sciences Investors, LLC | New | +1.6m |
| JPMORGAN CHASE & CO | New | +1.2m |
| VANGUARD CAPITAL MANAGEMENT LLC | New | +780.8k |
Biggest sellers
| None |
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| RA CAPITAL MANAGEMENT, L.P. 13G · passive investor new · filed 2026-05-11 | 16.6% |
AI DEN-MAB LLC
13D · may seek influence
new · filed 2026-05-11
Stated purposeThe Reporting Persons who hold Common Stock directly acquired those securities as an investment in the regular course of their businesses. The Reporting Persons may engage in discussions with management, the Issuer's board of directors, other stockholders of the Issuer and other relevant parties concerning the business, operations, board composition, management, strategy and future plans of the Issuer. Subject to the terms of the Investors' Rights Agreement (as defined below), the Reporting Persons intend to re-examine their investment from time to time and, depending on prevailing market conditions, other investment opportunities, liquidity requirements or other investment considerations the Reporting Persons deem material, the Reporting Persons may from time to time acquire additional Co… Full filing |
10.4% |
| Novo Holdings A/S 13G · exempt (held before listing) new · filed 2026-08-14 | 9.0% |
| Deep Track Capital, LP 13G · passive investor new · filed 2026-05-08 | 8.2% |
| FMR LLC 13G · institution new · filed 2026-08-06 | 7.9% |
| Capital International Investors 13G · institution new · filed 2026-08-12 | 7.7% |
| Avoro Capital Advisors LLC 13G · institution new · filed 2026-08-14 | 7.1% |
| Sofinnova Crossover II S.L.P. 13G · exempt (held before listing) new · filed 2026-08-05 | 5.4% |
| Invus Global Management, LLC 13G · passive investor new · filed 2026-08-07 | 5.1% |
Insider purchases and sales since 1 Apr 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2024 | 0 | — | 0 | — | — |
| Q1 2025 | 0 | — | 0 | — | — |
| Q2 2025 | 0 | — | 0 | — | — |
| Q3 2025 | 0 | — | 0 | — | — |
| Q4 2025 | 0 | — | 0 | — | — |
| Q1 2026 | 0 | — | 0 | — | — |
| Q2 2026 | 1 | $52.2m | 0 | — | — |
| Q3 2026 | 0 | — | 0 | — | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2026-06-16 | RA Capital Healthcare Fund LP +3 10% owner · See footnotes | Bought | $1.5m61.5k shares |
| 2026-06-15 | RA Capital Healthcare Fund LP +3 10% owner · See footnotes | Bought | $153.0k6.1k shares |
| 2026-05-20 | RA Capital Healthcare Fund LP +3 10% owner · See footnotes | Bought | $24.8k996 shares |
| 2026-05-19 | RA Capital Healthcare Fund LP +3 10% owner · See footnotes | Bought | $94.9k3.8k shares |
| 2026-05-12 | RA Capital Healthcare Fund LP +3 10% owner · See footnotes | Bought | $159.0k6.4k shares |
| 2026-05-11 | RA Capital Healthcare Fund LP +3 10% owner · See footnotes | Bought | $989.2k39.9k shares |
| 2026-05-08 | RA Capital Healthcare Fund LP +3 10% owner · See footnotes | Bought | $37.0k1.5k shares |
| 2026-05-07 | RA Capital Healthcare Fund LP +3 10% owner · See footnotes | Bought | $242.3k9.9k shares |
| 2026-05-06 | RA Capital Healthcare Fund LP +5 Director · See footnotes | Bought | $1.7m68.0k shares |
| 2026-05-05 | RA Capital Healthcare Fund LP +5 Director · See footnotes | Bought | $2.4m97.4k shares |
| 2026-05-04 | RA Capital Healthcare Fund LP +5 Director · See footnotes | Bought | $48.1m2.7m shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2026
| Manager | Shares | Change |
|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. 2.49% of their portfolio | 7.8m $286.8m | New |
| NOVO HOLDINGS A/S 8.92% of their portfolio | 4.2m $153.6m | New |
| FMR LLC 0.01% of their portfolio | 3.7m $135.8m | New |
| Capital International Investors 0.03% of their portfolio | 3.6m $132.4m | New |
| Deep Track Capital, LP 1.95% of their portfolio | 3.6m $132.3m | New |
| Siren, L.L.C. 1.56% of their portfolio | 2.1m $76.6m | New |
| Avoro Capital Advisors LLC 0.63% of their portfolio | 1.9m $70.7m | New |
| Bain Capital Life Sciences Investors, LLC 3.60% of their portfolio | 1.6m $60.6m | New |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 1.2m $42.3m | New |
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 780.8k $28.7m | New |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 746.0k $27.4m | New |
| Driehaus Capital Management LLC 0.15% of their portfolio | 715.8k $26.3m | New |
| Rock Springs Capital Management LP 1.03% of their portfolio | 575.4k $21.1m | New |
| Bellevue Group AG 0.43% of their portfolio | 550.0k $20.2m | New |
| CITADEL ADVISORS LLC 0.01% of their portfolio | 523.5k $19.2m | New |
| BlackRock, Inc. 0.00% of their portfolio | 283.8k $10.4m | New |
| DEERFIELD MANAGEMENT COMPANY, L.P. 0.11% of their portfolio | 275.0k $10.1m | New |
| ExodusPoint Capital Management, LP 0.07% of their portfolio | 218.3k $8.0m | New |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 211.8k $7.8m | New |
| BRAIDWELL LP 0.22% of their portfolio | 160.0k $5.9m | New |
| MARSHALL WACE, LLP 0.00% of their portfolio | 154.7k $5.7m | New |
| Woodline Partners LP 0.02% of their portfolio | 150.0k $5.5m | New |
| Affinity Asset Advisors, LLC 0.25% of their portfolio | 138.0k $5.1m | New |
| Ensign Peak Advisors, Inc 0.01% of their portfolio | 115.4k $4.2m | New |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 112.5k $4.1m | New |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 108.2k $4.0m | New |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 81.9k $3.0m | New |
| Burkehill Global Management, LP 0.10% of their portfolio | 75.0k $2.8m | New |
| Aberdeen Group plc 0.00% of their portfolio | 52.1k $1.9m | New |
| Opaleye Management Inc. 0.16% of their portfolio | 47.7k $1.8m | New |
| UBS Group AG 0.00% of their portfolio | 47.4k $1.7m | New |
| Parkman Healthcare Partners LLC 0.17% of their portfolio | 45.0k $1.7m | New |
| NORTHERN TRUST CORP 0.00% of their portfolio | 40.5k $1.5m | New |
| Ghisallo Capital Management LLC 0.03% of their portfolio | 40.0k $1.5m | New |
| TD Asset Management Inc 0.00% of their portfolio | 33.1k $1.2m | New |
| SEVEN GRAND MANAGERS, LLC 0.04% of their portfolio | 30.0k $1.1m | New |
| SOROS FUND MANAGEMENT LLC 0.01% of their portfolio | 25.0k $918.2k | New |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 18.7k $687.6k | New |
| GSA CAPITAL PARTNERS LLP 0.04% of their portfolio | 17.7k $649.0k | New |
| XTX Topco Ltd 0.01% of their portfolio | 17.4k $638.7k | New |
| LANDSCAPE CAPITAL MANAGEMENT, L.L.C. 0.03% of their portfolio | 13.2k $484.2k | New |
| Hudson Bay Capital Management LP 0.00% of their portfolio | 12.2k $448.2k | New |
| Schonfeld Strategic Advisors LLC 0.00% of their portfolio | 10.8k $397.2k | New |
| Weiss Asset Management LP 0.00% of their portfolio | 10.0k $367.3k | Not comparable |
| VANGUARD PORTFOLIO MANAGEMENT LLC 0.00% of their portfolio | 8.2k $300.0k | New |
| Vanguard Global Advisers, LLC 0.00% of their portfolio | 7.6k $279.7k | New |
| Squarepoint Ops LLC 0.00% of their portfolio | 6.3k $229.6k | New |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 5.7k $208.6k | New |
| MORGAN STANLEY 0.00% of their portfolio | 4.1k $149.8k | New |
| China Universal Asset Management Co., Ltd. 0.01% of their portfolio | 3.6k $132.2k | New |
| CITIGROUP INC 0.00% of their portfolio | 2.1k $76.9k | New |
| BARCLAYS PLC 0.00% of their portfolio | 1.0k $37.1k | New |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 248 $9.0k | New |
| JONES FINANCIAL COMPANIES LLLP 0.00% of their portfolio | 3 $97 | New |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 1 $37 | New |