4D MOLECULAR THERAPEUTICS IN FDMT
COM · Common Stock · CUSIP 35104E100
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersEmeryville, CA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($71.4k this quarter). Holder counts are more reliable. Implied quarter-end price ≈ $13.29. Options: 7 managers hold calls ($7.3m notional), 3 hold puts ($211.5k).
Trends to Q2 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 88 |
| Q4 2022 | 97 |
| Q1 2023 | 95 |
| Q2 2023 | 101 |
| Q3 2023 | 112 |
| Q4 2023 | 112 |
| Q1 2024 | 148 |
| Q2 2024 | 144 |
| Q3 2024 | 141 |
| Q4 2024 | 147 |
| Q1 2025 | 128 |
| Q2 2025 | 122 |
| Q3 2025 | 134 |
| Q4 2025 | 153 |
| Q1 2026 | 155 |
| Q2 2026 | 158 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2024 | 78 | 68 |
| Q4 2024 | 74 | 73 |
| Q1 2025 | 49 | 93 |
| Q2 2025 | 58 | 62 |
| Q3 2025 | 64 | 65 |
| Q4 2025 | 86 | 49 |
| Q1 2026 | 64 | 75 |
| Q2 2026 | 91 | 61 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2025 | $1.1m | $191.2k | 0.17 |
| Q4 2025 | $1.1m | $275.2k | 0.24 |
| Q1 2026 | $1.1m | $1.5m | 1.45 |
| Q2 2026 | $7.3m | $211.5k | 0.03 |
Biggest buyers
| T. Rowe Price Investment Management, Inc. | New | +2.5m |
| Trails Edge Capital Partners, LP | Added | +925.0k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | Added | +644.0k |
| DIADEMA PARTNERS LP | New | +571.1k |
| Catalio Capital Management, LP | New | +471.3k |
| Parkman Healthcare Partners LLC | Added | +425.6k |
| CITADEL ADVISORS LLC | Added | +423.5k |
| BlackRock, Inc. | Added | +400.8k |
| Schonfeld Strategic Advisors LLC | Added | +306.4k |
| ACUTA CAPITAL PARTNERS, LLC | Added | +265.5k |
Biggest sellers
| FEDERATED HERMES, INC. | Reduced | -1.2m |
| NOVO HOLDINGS A/S | Reduced | -401.6k |
| Peapod Lane Capital LLC | Sold out | -241.5k |
| Invesco Ltd. | Reduced | -160.3k |
| Exome Asset Management LLC | Sold out | -130.6k |
| Propel Bio Management, LLC | Reduced | -127.8k |
| ADAR1 Capital Management, LLC | Sold out | -116.7k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | -112.1k |
| VANGUARD CAPITAL MANAGEMENT LLC | Reduced | -96.5k |
| Privium Fund Management B.V. | Reduced | -80.1k |
Biggest calls
| CITADEL ADVISORS LLC | Added | $2.7m201.5k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $1.6m122.4k shares |
| Greenland Capital Management LP | New | $1.3m100.0k shares |
| Caption Management, LLC | New | $931.0k70.0k shares |
| GROUP ONE TRADING LLC | Added | $278.0k20.9k shares |
| JANE STREET GROUP, LLC | Reduced | $207.5k15.6k shares |
| SIMPLEX TRADING, LLC | Added | $200.8k15.1k shares |
Biggest puts
| CITADEL ADVISORS LLC | Reduced | $160.9k12.1k shares |
| GROUP ONE TRADING LLC | Reduced | $26.6k2.0k shares |
| SIMPLEX TRADING, LLC | Reduced | $23.9k1.8k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| JANUS HENDERSON GROUP PLC 13G · institution +2.2 pts · filed 2026-04-07 | 10.3% |
| BIOTECHNOLOGY VALUE FUND L P 13G · passive investor no change · filed 2026-05-15 | 10.0% |
| RA CAPITAL MANAGEMENT, L.P. 13G · passive investor no change · filed 2026-05-15 | 9.9% |
| GOLDMAN SACHS GROUP INC 13G · institution -2.1 pts · filed 2026-02-09 | 7.5% |
| BlackRock, Inc. 13G · institution -1.2 pts · filed 2025-10-17 | 6.6% |
| Novo Holdings A/S 13G · passive investor -0.4 pts · filed 2026-02-17 | 6.4% |
| STATE STREET CORP 13G · institution new · filed 2026-05-12 | 5.3% |
Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-26)
Insider purchases and sales since 1 Apr 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2024 | 0 | — | 0 | — | — |
| Q1 2025 | 0 | — | 0 | — | — |
| Q2 2025 | 0 | — | 0 | — | — |
| Q3 2025 | 0 | — | 1 | $19.3k | $19.3k |
| Q4 2025 | 0 | — | 2 | $111.4k | $108.0k |
| Q1 2026 | 0 | — | 1 | $3.4k | — |
| Q2 2026 | 0 | — | 2 | $1.4m | $1.4m |
| Q3 2026 | 0 | — | 2 | $3.1m | $3.1m |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2026-09-16 | Bizily Scott Chief Legal Officer | Sold plan | $22.3k1.6k shares |
| 2026-09-14 | Kirn David Officer, director | Sold plan | $810.8k58.3k shares |
| 2026-09-01 | Bizily Scott Chief Legal Officer | Sold plan | $8.2k584 shares |
| 2026-08-19 | Kirn David Officer, director | Sold plan | $1.1m69.1k shares |
| 2026-08-17 | Bizily Scott Chief Legal Officer | Sold plan | $19.9k1.6k shares |
| 2026-08-13 | Bizily Scott Chief Legal Officer | Sold plan | $19.6k1.6k shares |
| 2026-08-04 | Kirn David Officer, director | Sold plan | $274.6k26.8k shares |
| 2026-08-03 | Kirn David Officer, director | Sold plan | $124.8k12.4k shares |
| 2026-07-10 | Kirn David Officer, director | Sold plan | $189.2k15.7k shares |
| 2026-07-09 | Kirn David Officer, director | Sold plan | $548.4k42.6k shares |
| 2026-06-30 | Bizily Scott Chief Legal Officer | Sold plan | $91.9k6.6k shares |
| 2026-06-23 | Bizily Scott Chief Legal Officer | Sold plan | $117.7k9.8k shares |
| 2026-06-22 | Kirn David Officer, director | Sold plan | $1.2m114.7k shares |
| 2026-06-01 | Kirn David Officer, director | Sold plan | $19.3k1.9k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2026
| Manager | Shares | Change |
|---|---|---|
| Jupiter Topco LLC 0.03% of their portfolio | 5.7m $76.5m | First filing |
| RA CAPITAL MANAGEMENT, L.P. 0.58% of their portfolio | 5.0m $67.2m | Unchanged |
| BlackRock, Inc. 0.00% of their portfolio | 4.5m $60.5m | Added +400.8k |
| GOLDMAN SACHS GROUP INC 0.01% of their portfolio | 4.3m $56.6m | Added +53.2k |
| NOVO HOLDINGS A/S 2.51% of their portfolio | 3.2m $43.2m | Reduced -401.6k |
| STATE STREET CORP 0.00% of their portfolio | 2.9m $38.7m | Added +203.2k |
| BVF INC/IL 0.98% of their portfolio | 2.9m $38.3m | Unchanged |
| T. Rowe Price Investment Management, Inc. 0.02% of their portfolio | 2.5m $33.4m | New |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.04% of their portfolio | 2.2m $29.9m | Added +644.0k |
| Trails Edge Capital Partners, LP 4.70% of their portfolio | 2.2m $29.6m | Added +925.0k |
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 2.1m $27.9m | Reduced -96.5k |
| ARMISTICE CAPITAL, LLC 0.74% of their portfolio | 2.0m $26.6m | Unchanged |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 1.1m $15.0m | Added +63.1k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 1.1m $14.9m | Added +146.5k |
| Evergreen Quality Fund GP, Ltd. 0.20% of their portfolio | 951.5k $12.7m | Unchanged |
| Parkman Healthcare Partners LLC 1.30% of their portfolio | 948.2k $12.6m | Added +425.6k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 730.9k $9.7m | Added +208.0k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 710.9k $9.5m | Added +2.9k |
| CITADEL ADVISORS LLC 0.01% of their portfolio | 687.6k $9.1m | Added +423.5k |
| RENAISSANCE TECHNOLOGIES LLC 0.01% of their portfolio | 614.6k $8.2m | Added +36.3k |
| VANGUARD PORTFOLIO MANAGEMENT LLC 0.00% of their portfolio | 579.9k $7.7m | Added +24.1k |
| DIADEMA PARTNERS LP 2.68% of their portfolio | 571.1k $7.6m | New |
| NORTHERN TRUST CORP 0.00% of their portfolio | 562.9k $7.5m | Added +220.9k |
| ACUTA CAPITAL PARTNERS, LLC 4.71% of their portfolio | 507.8k $6.8m | Added +265.5k |
| Nuveen, LLC 0.00% of their portfolio | 503.1k $6.7m | Reduced -58.7k |
| MORGAN STANLEY 0.00% of their portfolio | 503.0k $6.7m | Added +157.6k |
| RTW INVESTMENTS, LP 0.05% of their portfolio | 475.7k $6.3m | Unchanged |
| Catalio Capital Management, LP 1.18% of their portfolio | 471.3k $6.3m | New |
| Schonfeld Strategic Advisors LLC 0.03% of their portfolio | 407.5k $5.4m | Added +306.4k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 402.1k $5.2m | Reduced -13.5k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 339.3k $4.5m | Added +10.9k |
| Opaleye Management Inc. 0.40% of their portfolio | 334.4k $4.4m | Added +222.1k |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 276.2k $3.7m | Added +6.9k |
| Burkehill Global Management, LP 0.13% of their portfolio | 275.0k $3.7m | Unchanged |
| UBS Group AG 0.00% of their portfolio | 256.7k $3.4m | Added +98.6k |
| Propel Bio Management, LLC 1.76% of their portfolio | 252.7k $3.4m | Reduced -127.8k |
| RAYMOND JAMES FINANCIAL INC 0.00% of their portfolio | 242.3k $3.2m | Reduced -23.8k |
| FEDERATED HERMES, INC. 0.00% of their portfolio | 222.4k $3.0m | Reduced -1.2m |
| ArrowMark Colorado Holdings LLC 0.11% of their portfolio | 202.9k $2.7m | Unchanged |
| Woodline Partners LP 0.01% of their portfolio | 200.0k $2.7m | Unchanged |
| Brevan Howard Capital Management LP 0.03% of their portfolio | 176.8k $2.4m | New |
| Assenagon Asset Management S.A. 0.00% of their portfolio | 166.7k $2.2m | Added +83.3k |
| ACADIAN ASSET MANAGEMENT LLC 0.00% of their portfolio | 163.5k $2.2m | Added +143.4k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 152.3k $2.0m | Added +18.7k |
| Invesco Ltd. 0.00% of their portfolio | 150.4k $2.0m | Reduced -160.3k |
| Perigon Wealth Management, LLC 0.03% of their portfolio | 146.2k $1.9m | Reduced -12 |
| Persistent Asset Partners Ltd 0.61% of their portfolio | 145.6k $1.9m | New |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 140.2k $1.9m | Added +94.8k |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 128.5k $1.7m | Added +19.6k |
| FMR LLC 0.00% of their portfolio | 128.3k $1.7m | Added +58.2k |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 114.0k $1.5m | Added +12.5k |
| Susquehanna Portfolio Strategies, LLC 0.02% of their portfolio | 106.9k $1.4m | Added +78.4k |
| Privium Fund Management B.V. 0.22% of their portfolio | 90.1k $1.2m | Reduced -80.1k |
| Greenland Capital Management LP 0.18% of their portfolio | 72.3k $961.0k | New |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 69.5k $924.1k | Reduced -54.8k |
| CITIGROUP INC 0.00% of their portfolio | 69.2k $920.5k | Added +43.0k |
| Man Group plc 0.00% of their portfolio | 68.3k $909.0k | Added +39.4k |
| Engineers Gate Manager LP 0.01% of their portfolio | 68.2k $907.1k | Added +38.8k |
| XTX Topco Ltd 0.01% of their portfolio | 67.1k $892.7k | Reduced -16.3k |
| SG Americas Securities, LLC 0.00% of their portfolio | 66.4k $884.0k | New |
| Fisher Asset Management, LLC 0.00% of their portfolio | 65.8k $874.5k | New |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 59.6k $793.2k | Added +5.5k |
| Quantinno Capital Management LP 0.00% of their portfolio | 58.1k $772.5k | Added +14.6k |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 56.3k $748.2k | Added +33.3k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 55.7k $518.9k | Added +640 |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 54.9k $730.0k | Added +12.4k |
| ALPS ADVISORS INC 0.00% of their portfolio | 53.1k $705.6k | New |
| TD Asset Management Inc 0.00% of their portfolio | 51.5k $684.7k | New |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 50.3k $668.7k | Added +4.5k |
| Birchview Capital, LP 0.30% of their portfolio | 48.5k $645.1k | New |
| PANAGORA ASSET MANAGEMENT INC 0.00% of their portfolio | 47.0k $624.9k | Reduced -346 |
| Rafferty Asset Management, LLC 0.00% of their portfolio | 44.7k $594.7k | Reduced -26.7k |
| D. E. Shaw & Co., Inc. 0.00% of their portfolio | 44.4k $589.9k | Added +20.3k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 41.7k $555.0k | Added +23.4k |
| Allspring Global Investments Holdings, LLC 0.00% of their portfolio | 37.2k $472.1k | New |
| Virtus Investment Advisers, LLC 0.11% of their portfolio | 37.1k $492.8k | Added +11.9k |
| DekaBank Deutsche Girozentrale 0.00% of their portfolio | 30.0k $256.0k | Unchanged |
| COMMONWEALTH EQUITY SERVICES, LLC 0.00% of their portfolio | 28.6k $380.0k | Added +300 |
| Creative Planning 0.00% of their portfolio | 28.3k $376.7k | Reduced -839 |
| OMERS ADMINISTRATION Corp 0.00% of their portfolio | 27.8k $369.7k | New |
| Mitsubishi UFJ Asset Management Co., Ltd. 0.00% of their portfolio | 26.6k $354.4k | Added +3.4k |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 26.4k $349.5k | Added +635 |
| MetLife Investment Management, LLC 0.00% of their portfolio | 26.1k $346.6k | Added +1.5k |
| Squarepoint Ops LLC 0.00% of their portfolio | 25.6k $340.2k | Reduced -36.9k |
| TRUIST FINANCIAL CORP 0.00% of their portfolio | 25.0k $332.5k | Unchanged |
| Peloton Wealth Strategists 0.12% of their portfolio | 25.0k $333.0k | Unchanged |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.01% of their portfolio | 25.0k $332.5k | Reduced -25.0k |
| CANADA PENSION PLAN INVESTMENT BOARD 0.00% of their portfolio | 24.7k $328.5k | New |
| Kera Capital Partners, Inc. 0.03% of their portfolio | 24.1k $320.1k | Unchanged |
| BARCLAYS PLC 0.00% of their portfolio | 23.8k $316.9k | Reduced -1.6k |
| Rockefeller Capital Management L.P. 0.00% of their portfolio | 23.7k $315.6k | Added +5.9k |
| Jain Global LLC 0.00% of their portfolio | 23.5k $313.0k | New |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 23.5k $312.0k | Added +20.3k |
| PROFUND ADVISORS LLC 0.01% of their portfolio | 22.7k $301.9k | Reduced -9.2k |
| MARSHALL WACE, LLP 0.00% of their portfolio | 21.3k $283.8k | Added +4.6k |
| Rangeley Capital, LLC 0.26% of their portfolio | 21.0k $278.8k | Reduced -10.5k |
| Headlands Technologies LLC 0.03% of their portfolio | 19.2k $255.9k | Added +3.3k |
| Landing Point Financial Group, LLC 0.08% of their portfolio | 18.5k $246.1k | Reduced -500 |
| Parallel Advisors, LLC 0.00% of their portfolio | 17.9k $237.9k | Unchanged |
| SEI INVESTMENTS CO 0.00% of their portfolio | 16.7k $221.6k | Added +3.8k |