STANDARD BIOTOOLS INC LAB
COM · Common Stock · CUSIP 34385P108
Company in South San Francisco, United States
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersBoston, MA
- Founded1999
- Websitestandardbio.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($347.4k this quarter). Holder counts are more reliable. Shares outstanding: 392.6m as of 2026-08-03, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $0.82. Options: 3 managers hold calls ($26.0k notional), 2 hold puts ($58.0k).
Trends to Q2 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 66 |
| Q4 2022 | 68 |
| Q1 2023 | 69 |
| Q2 2023 | 67 |
| Q3 2023 | 73 |
| Q4 2023 | 87 |
| Q1 2024 | 146 |
| Q2 2024 | 146 |
| Q3 2024 | 142 |
| Q4 2024 | 143 |
| Q1 2025 | 146 |
| Q2 2025 | 161 |
| Q3 2025 | 155 |
| Q4 2025 | 159 |
| Q1 2026 | 156 |
| Q2 2026 | 143 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2024 | 57 | 67 |
| Q4 2024 | 62 | 62 |
| Q1 2025 | 61 | 57 |
| Q2 2025 | 73 | 58 |
| Q3 2025 | 63 | 60 |
| Q4 2025 | 64 | 66 |
| Q1 2026 | 69 | 70 |
| Q2 2026 | 88 | 87 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2025 | $108.6k | $69.0k | 0.64 |
| Q4 2025 | $51.1k | $68.2k | 1.34 |
| Q1 2026 | $20.2k | $19.5k | 0.96 |
| Q2 2026 | $26.0k | $58.0k | 2.23 |
Biggest buyers
| Long Focus Capital Management, LLC | Added | +7.5m |
| Qube Research & Technologies Ltd | Added | +4.1m |
| MAK CAPITAL ONE LLC | Added | +2.6m |
| D. E. Shaw & Co., Inc. | Added | +2.6m |
| JANE STREET GROUP, LLC | New | +2.5m |
| Mink Brook Asset Management LLC | New | +2.2m |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | New | +2.0m |
| JACOBS LEVY EQUITY MANAGEMENT, INC | New | +1.6m |
| ROYCE & ASSOCIATES LP | Added | +1.5m |
| MILLENNIUM MANAGEMENT LLC | Added | +1.4m |
Biggest sellers
| BlackRock, Inc. | Reduced | -16.5m |
| STATE STREET CORP | Reduced | -5.0m |
| GEODE CAPITAL MANAGEMENT, LLC | Reduced | -3.4m |
| BARCLAYS PLC | Reduced | -2.6m |
| VANGUARD PORTFOLIO MANAGEMENT LLC | Reduced | -1.7m |
| NORTHERN TRUST CORP | Reduced | -1.7m |
| Slate Path Capital LP | Sold out | -1.6m |
| GOLDMAN SACHS GROUP INC | Reduced | -726.8k |
| Bank of New York Mellon Corp | Reduced | -676.7k |
| Nuveen, LLC | Sold out | -661.2k |
Biggest calls
| JANE STREET GROUP, LLC | New | $11.4k13.9k shares |
| CITADEL ADVISORS LLC | Reduced | $11.3k13.7k shares |
| SIMPLEX TRADING, LLC | New | $3.3k4.0k shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | New | $45.9k56.0k shares |
| CITADEL ADVISORS LLC | Reduced | $12.1k14.7k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
Casdin Capital, LLC
13D · may seek influence
-0.3 pts · filed 2026-06-09
Stated purposeItem 4 of the Schedule 13D amendment filed on November 28, 2025 is hereby supplemented by the addition of the following: On June 6, 2026, the Issuer, Treeline Biosciences, Inc., a Delaware corporation (the "Company"), and Siri Merger Sub, Inc., a Delaware corporation and a wholly owned subsidiary of the Issuer ("Merger Sub"), entered into an Agreement and Plan of Merger and Reorganization (the "Merger Agreement"), pursuant to which, among other matters, and subject to the satisfaction or waiver of the conditions set forth in the Merger Agreement, Merger Sub will merge with and into the Company, with the Company continuing as a wholly owned subsidiary of the Issuer and the surviving corporation of the merger (the "Merger"). Upon the terms and subject to the conditions set forth in the Merg… Full filing |
23.9% |
VIKING GLOBAL INVESTORS LP
13D · may seek influence
no change · filed 2026-06-12
Stated purposeThe response to Item 3 of this Schedule 13D is incorporated by reference herein. On June 6, 2026, the Issuer, Treeline Biosciences, Inc., a Delaware corporation ("Treeline"), and Siri Merger Sub, Inc., a Delaware corporation and a wholly owned subsidiary of the Issuer ("Merger Sub"), entered into an Agreement and Plan of Merger and Reorganization (the "Merger Agreement"), pursuant to which, among other matters, and subject to the satisfaction or waiver of the conditions set forth in the Merger Agreement, Merger Sub will merge with and into Treeline, with Treeline continuing as a wholly owned subsidiary of the Issuer and the surviving corporation of the merger (the "Merger"). Upon the terms and subject to the conditions set forth in the Merger Agreement, at the effective time of the Merger… Full filing |
15.0% |
| MAK CAPITAL ONE LLC 13G · passive investor filed 2026-08-14 | 7.3% |
| MAK Capital Fund LP 13G · passive investor +1.5 pts · filed 2026-05-15 | 6.7% |
| Long Focus Capital Management, LLC 13G · institution new · filed 2026-08-14 | 6.0% |
Fell to 5% or below in the last year: BlackRock, Inc. (2.0%, 2026-07-30)
Insider purchases and sales since 1 Apr 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2024 | 0 | — | 0 | — | — |
| Q1 2025 | 1 | $5.2m | 0 | — | — |
| Q2 2025 | 0 | — | 3 | $57.5k | — |
| Q3 2025 | 1 | $1.9m | 0 | — | — |
| Q4 2025 | 1 | $14.4m | 0 | — | — |
| Q1 2026 | 0 | — | 0 | — | — |
| Q2 2026 | 0 | — | 0 | — | — |
| Q3 2026 | 0 | — | 0 | — | — |
None reported since 1 Apr 2026.
Holders, Q2 2026
| Manager | Shares | Change |
|---|---|---|
| Casdin Capital, LLC 3.66% of their portfolio | 88.8m $73.0m | Unchanged |
| VIKING GLOBAL INVESTORS LP 0.14% of their portfolio | 58.7m $48.3m | Unchanged |
| MAK CAPITAL ONE LLC 3.32% of their portfolio | 28.8m $23.7m | Added +2.6m |
| Long Focus Capital Management, LLC 0.79% of their portfolio | 23.5m $19.3m | Added +7.5m |
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 12.3m $10.1m | Reduced -563.1k |
| BlackRock, Inc. 0.00% of their portfolio | 8.3m $6.8m | Reduced -16.5m |
| Hollow Brook Wealth Management LLC 0.90% of their portfolio | 5.5m $4.5m | Reduced -150.0k |
| NEUBERGER BERMAN GROUP LLC 0.00% of their portfolio | 5.0m $4.0m | Added +301.0k |
| Qube Research & Technologies Ltd 0.00% of their portfolio | 4.8m $4.0m | Added +4.1m |
| ROYCE & ASSOCIATES LP 0.03% of their portfolio | 4.5m $3.7m | Added +1.5m |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 3.9m $3.2m | Reduced -3.4m |
| Tikvah Management LLC 0.89% of their portfolio | 3.6m $2.9m | Reduced -94 |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 3.5m $2.9m | Added +1.4m |
| MORGAN STANLEY 0.00% of their portfolio | 2.8m $2.3m | Reduced -55.5k |
| D. E. Shaw & Co., Inc. 0.00% of their portfolio | 2.8m $2.3m | Added +2.6m |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 2.5m $2.1m | New |
| Peapod Lane Capital LLC 1.34% of their portfolio | 2.4m $2.0m | Added +382.9k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 2.3m $1.9m | Added +1.1m |
| Mink Brook Asset Management LLC 0.80% of their portfolio | 2.2m $1.8m | New |
| Sone Capital Management, LLC 0.13% of their portfolio | 2.1m $1.8m | Added +366.9k |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP 0.00% of their portfolio | 2.0m $1.6m | New |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 1.9m $1.6m | Reduced -27.6k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 1.8m $1.4m | Reduced -655.7k |
| JACOBS LEVY EQUITY MANAGEMENT, INC 0.00% of their portfolio | 1.6m $1.3m | New |
| STATE STREET CORP 0.00% of their portfolio | 1.5m $1.3m | Reduced -5.0m |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 1.4m $1.1m | Added +425.9k |
| Loews Corp 0.01% of their portfolio | 1.2m $1.0m | New |
| GSA CAPITAL PARTNERS LLP 0.06% of their portfolio | 1.2m $977.0k | Added +834.2k |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 992.1k $816.2k | New |
| STALEY CAPITAL ADVISERS INC 0.03% of their portfolio | 800.0k $658.2k | Added +167.6k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 791.5k $651.2k | Reduced -1.7m |
| Man Group plc 0.00% of their portfolio | 742.8k $611.1k | New |
| Point72 Asset Management, L.P. 0.00% of their portfolio | 708.0k $582.5k | Added +663.3k |
| VANGUARD PORTFOLIO MANAGEMENT LLC 0.00% of their portfolio | 674.7k $555.3k | Reduced -1.7m |
| Aster Capital Management (DIFC) Ltd 0.09% of their portfolio | 541.1k $445.2k | New |
| Jain Global LLC 0.00% of their portfolio | 467.3k $384.5k | New |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 434.3k $357.3k | Added +281.0k |
| Rockefeller Capital Management L.P. 0.00% of their portfolio | 428.5k $352.5k | Reduced -98.9k |
| UBS Group AG 0.00% of their portfolio | 426.0k $350.6k | Added +120.9k |
| Sumitomo Mitsui Trust Group, Inc. 0.00% of their portfolio | 412.3k $339.2k | Reduced -30.5k |
| Amova Asset Management Americas, Inc. 0.00% of their portfolio | 412.3k $338.1k | Reduced -30.5k |
| Intellectus Partners, LLC 0.06% of their portfolio | 404.7k $332.9k | Unchanged |
| HighTower Advisors, LLC 0.00% of their portfolio | 355.6k $292.5k | Added +301.1k |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 328.6k $270.3k | Added +14.4k |
| OPPENHEIMER & CO INC 0.00% of their portfolio | 326.6k $268.7k | Reduced -24.3k |
| Marquette Asset Management, LLC 0.03% of their portfolio | 325.3k $267.7k | New |
| JOHNSON & JOHNSON 0.03% of their portfolio | 312.0k $256.7k | Unchanged |
| Susquehanna Portfolio Strategies, LLC 0.00% of their portfolio | 291.5k $239.8k | New |
| XTX Topco Ltd 0.00% of their portfolio | 277.8k $228.6k | Reduced -51.1k |
| Squarepoint Ops LLC 0.00% of their portfolio | 277.4k $228.2k | New |
| HSBC HOLDINGS PLC 0.00% of their portfolio | 271.5k $218.8k | New |
| Y-Intercept (Hong Kong) Ltd 0.00% of their portfolio | 263.3k $216.6k | New |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 244.1k $200.6k | Reduced -176.5k |
| Brevan Howard Capital Management LP 0.00% of their portfolio | 242.3k $199.4k | New |
| QVIDTVM Management LLC 0.24% of their portfolio | 222.0k $182.6k | Reduced -7.3k |
| Invesco Ltd. 0.00% of their portfolio | 221.9k $182.6k | Reduced -36.4k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 216.4k $178.1k | Reduced -726.8k |
| IEQ CAPITAL, LLC 0.00% of their portfolio | 199.9k $164.4k | Added +81.3k |
| PRIMECAP MANAGEMENT CO/CA/ 0.00% of their portfolio | 153.4k $126.2k | Unchanged |
| Vanguard Global Advisers, LLC 0.00% of their portfolio | 129.3k $106.4k | Unchanged |
| Evercore Wealth Management, LLC 0.00% of their portfolio | 125.0k $102.8k | Unchanged |
| Schonfeld Strategic Advisors LLC 0.00% of their portfolio | 118.6k $97.6k | New |
| Catalyst Funds Management Pty Ltd 0.01% of their portfolio | 110.8k $91.2k | New |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 104.8k $86.2k | New |
| MERCER GLOBAL ADVISORS INC /ADV 0.00% of their portfolio | 101.4k $83.4k | Added +38.6k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 98.4k $81.0k | Reduced -266.5k |
| Virtu Financial LLC 0.00% of their portfolio | 97.2k $80.0k | New |
| Mariner, LLC 0.00% of their portfolio | 91.5k $75.3k | Added +44.4k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 90.3k $74.3k | Reduced -676.7k |
| Creative Planning 0.00% of their portfolio | 80.3k $66.1k | Added +61.9k |
| State of Wyoming 0.01% of their portfolio | 75.3k $61.9k | Added +72.6k |
| BOOTHBAY FUND MANAGEMENT, LLC 0.00% of their portfolio | 70.8k $58.2k | Reduced -1.8k |
| Engineers Gate Manager LP 0.00% of their portfolio | 68.7k $56.5k | New |
| Hudson Bay Capital Management LP 0.00% of their portfolio | 64.0k $52.7k | New |
| PRUDENTIAL FINANCIAL INC 0.00% of their portfolio | 60.3k $49.6k | Added +12.9k |
| SG Americas Securities, LLC 0.00% of their portfolio | 56.6k $47.0k | Added +35.7k |
| ACADIAN ASSET MANAGEMENT LLC 0.00% of their portfolio | 53.4k $43.0k | New |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO 0.00% of their portfolio | 51.9k $41.9k | New |
| Cerity Partners LLC 0.00% of their portfolio | 50.0k $41.1k | Added +5.9k |
| Focus Partners Wealth 0.00% of their portfolio | 46.6k $38.3k | Added +22.3k |
| BARCLAYS PLC 0.00% of their portfolio | 43.9k $36.1k | Reduced -2.6m |
| VICTORY CAPITAL MANAGEMENT INC 0.00% of their portfolio | 43.4k $35.7k | Added +1.2k |
| PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO 0.00% of their portfolio | 42.6k $35.0k | Unchanged |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC 0.00% of their portfolio | 42.1k $38.7k | Added +11.6k |
| Balyasny Asset Management L.P. 0.00% of their portfolio | 38.5k $31.7k | New |
| NEEDHAM INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 34.4k $28.3k | Unchanged |
| Atom Investors LP 0.00% of their portfolio | 29.6k $24.3k | New |
| CAPTRUST FINANCIAL ADVISORS 0.00% of their portfolio | 28.7k $23.6k | Added +10.0k |
| EverSource Wealth Advisors, LLC 0.00% of their portfolio | 27.8k $22.9k | Added +1.3k |
| ExodusPoint Capital Management, LP 0.00% of their portfolio | 26.9k $22.1k | New |
| Platform Technology Partners 0.00% of their portfolio | 25.0k $20.6k | Unchanged |
| Corient Private Wealth LP 0.00% of their portfolio | 24.7k $20.4k | Added +11.7k |
| SEI INVESTMENTS CO 0.00% of their portfolio | 24.0k $19.8k | Reduced -36.1k |
| CITIGROUP INC 0.00% of their portfolio | 23.4k $19.3k | Reduced -7.9k |
| BRIGHTON JONES LLC 0.00% of their portfolio | 21.9k $18.1k | Added +10.5k |
| Laurion Capital Management LP 0.00% of their portfolio | 21.8k $18.0k | New |
| Connor, Clark & Lunn Investment Management Ltd. 0.00% of their portfolio | 20.8k $17.1k | New |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 18.9k $15.0k | Added +18.6k |
| Jefferies Financial Group Inc. 0.00% of their portfolio | 17.7k $14.5k | New |
| Merit Financial Group, LLC 0.00% of their portfolio | 14.5k $12.0k | Added +3.0k |