Vault-13

ESPERION THERAPEUTICS INC NE ESPR

COM · Common Stock · CUSIP 29664W105 · ISIN US29664W1053

164 institutional holders +16 vs Q3 2022
73,757,13373.8m shares reported held*
$459.5mreported value*
37 new 56 added 39 reduced 26 sold out net bought ≈ $39.1m (+6.3m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($1.0m this quarter). Holder counts are more reliable. Implied quarter-end price ≈ $6.23. Options: 21 managers hold calls ($50.2m notional), 14 hold puts ($14.2m).

Trends to Q4 2022

Institutional holders

Managers reporting a position, each quarter

0100200Q3 22: 148Q4 22: 164164Q3 22Q4 22
Numbers
QuarterHolders
Q3 2022148
Q4 2022164

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$20m$40m$60mQ3 22 calls: $22.5mQ3 22 puts: $4.1mQ3 22P/C 0.18Q4 22 calls: $50.2mQ4 22 puts: $14.2mQ4 22P/C 0.28
Numbers
QuarterCallsPutsP/C
Q3 2022$22.5m$4.1m0.18
Q4 2022$50.2m$14.2m0.28

Biggest buyers

Balyasny Asset Management L.P. Added +2,633,466+2.6m
CITADEL ADVISORS LLC Added +1,035,258+1.0m
BlackRock Inc. Added +950,543+950.5k
LORD, ABBETT & CO. LLC New +934,932+934.9k
Jefferies Financial Group Inc. New +904,877+904.9k
ExodusPoint Capital Management, LP Added +806,848+806.8k
AXA S.A. New +788,366+788.4k
MORGAN STANLEY Added +776,442+776.4k
Nuveen Asset Management, LLC Added +717,837+717.8k
VOLORIDGE INVESTMENT MANAGEMENT, LLC New +679,530+679.5k

Biggest sellers

Paradigm Biocapital Advisors LP Sold out -1,719,831-1.7m
Deep Track Capital, LP Reduced -1,636,587-1.6m
Woodline Partners LP Reduced -771,891-771.9k
Walleye Capital LLC Sold out -698,343-698.3k
WASATCH ADVISORS LP Reduced -614,638-614.6k
Point72 Asset Management, L.P. Reduced -511,300-511.3k
TANG CAPITAL MANAGEMENT LLC Sold out -500,000-500.0k
Invesco Ltd. Reduced -467,906-467.9k
Commodore Capital LP Sold out -467,468-467.5k
MARSHALL WACE, LLP Reduced -385,964-386.0k

Biggest calls

Caption Management, LLC Added $11.0m1.8m shares
Ikarian Capital, LLC Added $8.1m1.3m shares
SIMPLEX TRADING, LLC Added $5.6m900.9k shares
GROUP ONE TRADING LLC Added $4.9m794.0k shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Added $3.7m590.2k shares
J. Goldman & Co LP New $2.9m472.5k shares
HIGHBRIDGE CAPITAL MANAGEMENT LLC New $2.9m457.4k shares
CITADEL ADVISORS LLC Added $2.6m412.1k shares
Walleye Trading LLC Added $1.6m263.6k shares
MILLENNIUM MANAGEMENT LLC New $1.5m247.5k shares

Biggest puts

SUSQUEHANNA INTERNATIONAL GROUP, LLP Added $4.1m656.5k shares
SIMPLEX TRADING, LLC Added $2.0m324.5k shares
GROUP ONE TRADING LLC Added $2.0m320.2k shares
CITADEL ADVISORS LLC Added $1.4m226.9k shares
J. Goldman & Co LP New $1.3m202.5k shares
Point72 Asset Management, L.P. Added $934.5k150.0k shares
SABBY MANAGEMENT, LLC Added $734.5k1.2k shares
JANE STREET GROUP, LLC Added $674.1k108.2k shares
Walleye Trading LLC Reduced $383.1k61.5k shares
Sculptor Capital LP Unchanged $289.7k46.5k shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
GLAZER CAPITAL, LLC 13G · passive investor new · filed 2026-06-08 8.2% new 21.0m≈ $66.3m 2026-06-08
GOLDMAN SACHS GROUP INC 13G · institution new · filed 2026-08-13 6.7% new 17.2m≈ $54.4m 2026-08-13
VANGUARD CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-07-31 5.1% new 13.1m≈ $41.4m 2026-07-31

Fell to 5% or below in the last year: WASATCH ADVISORS LP (0.7%, 2026-07-14), VANGUARD GROUP INC (0.0%, 2026-03-26; now reported by VANGUARD CAPITAL MANAGEMENT LLC), Two Seas Capital LP (4.7%, 2025-11-14)

Holders, Q4 2022

#ManagerLocationShares Value% of their portfolioChangeShares change
1 WASATCH ADVISORS LP 0.29% of their portfolio SALT LAKE CITY, UT 6,848,3786.8m $42.7m $42.7m 0.29% Reduced -614.6k -614,638
2 BlackRock Inc. 0.00% of their portfolio New York, NY 5,509,1875.5m $34.3m $34.3m 0.00% Added +950.5k +950,543
3 Meditor Group Ltd 18.82% of their portfolio HAMILTON, D0 4,468,8354.5m $27.8m $27.8m 18.82% Unchanged
4 Bellevue Group AG 0.36% of their portfolio ZURICH, V8 4,330,2644.3m $27.0m $27.0m 0.36% Added +105.0k +105,000
5 VANGUARD GROUP INC 0.00% of their portfolio Valley Forge, PA 4,260,4644.3m $26.5m $26.5m 0.00% Added +221.9k +221,939
6 Deep Track Capital, LP 1.09% of their portfolio GREENWICH, CT 4,000,0004.0m $24.9m $24.9m 1.09% Reduced -1.6m -1,636,587
7 Balyasny Asset Management L.P. 0.08% of their portfolio Chicago, IL 3,429,1373.4m $21.4m $21.4m 0.08% Added +2.6m +2,633,466
8 BRAIDWELL LP 0.71% of their portfolio STAMFORD, CT 3,393,4053.4m $21.1m $21.1m 0.71% First filing
9 Point72 Asset Management, L.P. 0.05% of their portfolio STAMFORD, CT 2,277,0002.3m $14.2m $14.2m 0.05% Reduced -511.3k -511,300
10 MILLENNIUM MANAGEMENT LLC 0.02% of their portfolio NEW YORK, NY 2,226,8092.2m $13.9m $13.9m 0.02% Added +503.6k +503,634
11 Ikarian Capital, LLC 4.89% of their portfolio DALLAS, TX 1,891,1471.9m $11.8m $11.8m 4.89% Reduced -240.0k -240,000
12 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 1,786,2231.8m $11.1m $11.1m 0.00% Added +776.4k +776,442
13 STATE STREET CORP 0.00% of their portfolio BOSTON, MA 1,754,3091.8m $10.9m $10.9m 0.00% Added +221.2k +221,161
14 CITADEL ADVISORS LLC 0.01% of their portfolio MIAMI, FL 1,549,9961.5m $9.7m $9.7m 0.01% Added +1.0m +1,035,258
15 TWO SIGMA INVESTMENTS, LP 0.03% of their portfolio NEW YORK, NY 1,537,6641.5m $9.6m $9.6m 0.03% Added +469.2k +469,226
16 PLATINUM INVESTMENT MANAGEMENT LTD 0.34% of their portfolio SYDNEY AUSTRALIA 2000, C3 1,430,0011.4m $8.9m $8.9m 0.34% Unchanged
17 TWO SIGMA ADVISERS, LP 0.02% of their portfolio NEW YORK, NY 1,416,0001.4m $8.8m $8.8m 0.02% Added +331.7k +331,700
18 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 1,279,9241.3m $8.0m $8.0m 0.00% Added +152.3k +152,344
19 ExodusPoint Capital Management, LP 0.11% of their portfolio NEW YORK, NY 1,171,7991.2m $7.3m $7.3m 0.11% Added +806.8k +806,848
20 Nuveen Asset Management, LLC 0.00% of their portfolio CHICAGO, IL 1,019,1961.0m $6.3m $6.3m 0.00% Added +717.8k +717,837
21 LORD, ABBETT & CO. LLC 0.01% of their portfolio JERSEY CITY, NJ 934,932934.9k $5.8m $5.8m 0.01% New
22 Jefferies Financial Group Inc. 0.10% of their portfolio NEW YORK, NY 904,877904.9k $5.6m $5.6m 0.10% New
23 Rhenman & Partners Asset Management AB 0.58% of their portfolio Stockholm, V7 900,000900.0k $5.6m $5.6m 0.58% Unchanged
24 Parkman Healthcare Partners LLC 1.36% of their portfolio STAMFORD, CT 822,784822.8k $5.1m $5.1m 1.36% Added +526.4k +526,403
25 AXA S.A. 0.02% of their portfolio PARIS, I0 788,366788.4k $4.9m $4.9m 0.02% New
26 NORGES BANK 0.00% of their portfolio OSLO, Q8 735,900735.9k $4.6m $4.6m 0.00% Not comparable
27 GOLDMAN SACHS GROUP INC 0.00% of their portfolio NEW YORK, NY 728,338728.3k $4.5m $4.5m 0.00% Added +262.5k +262,539
28 Schonfeld Strategic Advisors LLC 0.04% of their portfolio NEW YORK, NY 707,052707.1k $4.4m $4.4m 0.04% Reduced -96.0k -96,017
29 VOLORIDGE INVESTMENT MANAGEMENT, LLC 0.02% of their portfolio JUPITER, FL 679,530679.5k $4.2m $4.2m 0.02% New
30 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 665,083665.1k $4.1m $4.1m 0.00% Added +83.1k +83,075
31 Graham Capital Management, L.P. 0.15% of their portfolio ROWAYTON, CT 621,174621.2k $3.9m $3.9m 0.15% New
32 Altium Capital Management LLC 1.98% of their portfolio NEW YORK, NY 620,000620.0k $3.9m $3.9m 1.98% Reduced -39.9k -39,869
33 HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND 0.02% of their portfolio TORONTO, A6 534,200534.2k $3.3m $3.3m 0.02% New
34 Hudson Bay Capital Management LP 0.04% of their portfolio STAMFORD, CT 500,000500.0k $3.1m $3.1m 0.04% New
35 Monaco Asset Management SAM 1.04% of their portfolio Monaco, O9 470,100470.1k $2.9m $2.9m 1.04% Added +210.1k +210,100
36 Woodline Partners LP 0.04% of their portfolio San Francisco, CA 423,814423.8k $2.6m $2.6m 0.04% Reduced -771.9k -771,891
37 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 375,846375.8k $2.3m $2.3m 0.00% Reduced -25.0k -24,990
38 PURA VIDA INVESTMENTS, LLC 0.32% of their portfolio NEW YORK, NY 308,313308.3k $1.9m $1.9m 0.32% Reduced -23.8k -23,810
39 J. Goldman & Co LP 0.13% of their portfolio NEW YORK, NY 293,864293.9k $1.8m $1.8m 0.13% Reduced -259.1k -259,146
40 Bank of New York Mellon Corp 0.00% of their portfolio NEW YORK, NY 286,286286.3k $1.8m $1.8m 0.00% Added +13.9k +13,880
41 Connor, Clark & Lunn Investment Management Ltd. 0.01% of their portfolio VANCOUVER, A1 283,546283.5k $1.8m $1.8m 0.01% Added +132.0k +132,042
42 GROUP ONE TRADING LLC 0.06% of their portfolio CHICAGO, IL 261,351261.4k $1.6m $1.6m 0.06% New
43 HIGHBRIDGE CAPITAL MANAGEMENT LLC 0.05% of their portfolio NEW YORK, NY 254,265254.3k $1.6m $1.6m 0.05% Reduced -165.7k -165,653
44 WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio Boston, MA 245,074245.1k $1.5m $1.5m 0.00% Reduced -29.4k -29,351
45 PINNACLE ASSOCIATES LTD 0.03% of their portfolio NEW YORK, NY 238,756238.8k $1.5m $1.5m 0.03% Reduced -3.9k -3,860
46 BOOTHBAY FUND MANAGEMENT, LLC 0.04% of their portfolio NEW YORK, NY 233,435233.4k $1.5m $1.5m 0.04% Reduced -29.6k -29,623
47 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio SAN FRANCISCO, CA 196,952197.0k $1.2m $1.2m 0.00% Added +27.1k +27,126
48 NOMURA HOLDINGS INC 0.01% of their portfolio TOKYO, M0 189,299189.3k $1.2m $1.2m 0.01% New
49 MARSHALL WACE, LLP 0.00% of their portfolio LONDON, X0 175,023175.0k $1.1m $1.1m 0.00% Reduced -386.0k -385,964
50 BARCLAYS PLC 0.00% of their portfolio LONDON, X0 163,021163.0k $1.0m $1.0m 0.00% First filing
51 Cubist Systematic Strategies, LLC 0.01% of their portfolio STAMFORD, CT 161,138161.1k $1.0m $1.0m 0.01% Reduced -199.9k -199,914
52 SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio BALA CYNWYD, PA 157,235157.2k $979.6k $979.6k 0.00% Added +132.4k +132,384
53 JACOBS LEVY EQUITY MANAGEMENT, INC 0.01% of their portfolio FLORHAM PARK, NJ 146,019146.0k $909.7k $909.7k 0.01% New
54 LAZARD ASSET MANAGEMENT LLC 0.00% of their portfolio NEW YORK, NY 145,953146.0k $909.0k $909.0k 0.00% Added +62.4k +62,385
55 PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO 0.00% of their portfolio COLUMBUS, OH 142,722142.7k $889.0k $889.0k 0.00% Reduced -25.8k -25,830
56 Pentwater Capital Management LP 0.03% of their portfolio Naples, FL 140,127140.1k $873.0k $873.0k 0.03% Reduced -115.0k -114,965
57 SIMPLEX TRADING, LLC 0.04% of their portfolio CHICAGO, IL 139,427139.4k $868.0k $868.0k 0.04% New
58 Swiss National Bank 0.00% of their portfolio ZURICH, V8 136,600136.6k $851.0k $851.0k 0.00% New
59 Squarepoint Ops LLC 0.01% of their portfolio NEW YORK, NY 131,536131.5k $819.5k $819.5k 0.01% Added +73.7k +73,674
60 FMR LLC 0.00% of their portfolio BOSTON, MA 94,97495.0k $591.7k $591.7k 0.00% Added +86.7k +86,660
61 RHUMBLINE ADVISERS 0.00% of their portfolio BOSTON, MA 92,82892.8k $578.0k $578.0k 0.00% Added +7.2k +7,216
62 BANK OF AMERICA CORP /DE/ 0.00% of their portfolio CHARLOTTE, NC 87,49587.5k $545.1k $545.1k 0.00% Added +21.7k +21,729
63 WOLVERINE ASSET MANAGEMENT LLC 0.01% of their portfolio CHICAGO, IL 87,38487.4k $544.4k $544.4k 0.01% Reduced -57.9k -57,861
64 TUDOR INVESTMENT CORP ET AL 0.01% of their portfolio STAMFORD, CT 84,94984.9k $529.0k $529.0k 0.01% Added +13.5k +13,505
65 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio WEST SACRAMENTO, CA 78,56878.6k $489.5k $489.5k 0.00% Added +52.3k +52,275
66 UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio NEW YORK, NY 71,69571.7k $446.7k $446.7k 0.00% New
67 Telemetry Investments, L.L.C. 1.03% of their portfolio NEW YORK, NY 71,00071.0k $442.0k $442.0k 1.03% New
68 ARISTEIA CAPITAL, L.L.C. 0.01% of their portfolio GREENWICH, CT 70,95971.0k $442.1k $442.1k 0.01% Reduced -45.0k -44,992
69 SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC 0.01% of their portfolio BALA CYNWYD, PA 70,71670.7k $440.6k $440.6k 0.01% New
70 BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio PARIS, I0 69,30969.3k $431.8k $431.8k 0.00% Added +39.9k +39,900
71 MACKENZIE FINANCIAL CORP 0.00% of their portfolio TORONTO ONTARIO, A6 67,84367.8k $422.7k $422.7k 0.00% New
72 CREDIT SUISSE AG/ 0.00% of their portfolio ZURICH, V8 61,93261.9k $385.8k $385.8k 0.00% Added +45.8k +45,809
73 JANE STREET GROUP, LLC 0.00% of their portfolio NEW YORK, NY 61,44561.4k $382.8k $382.8k 0.00% Added +38.3k +38,330
74 OSAIC HOLDINGS, INC. 0.00% of their portfolio SCOTTSDALE, AZ 58,62458.6k $365.8k $365.8k 0.00% Added +51.8k +51,801
75 STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio MADISON, WI 56,65656.7k $353.0k $353.0k 0.00% Added +8.3k +8,264
76 ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio NASHVILLE, TN 54,60054.6k $340.2k $340.2k 0.00% Added +11.6k +11,647
77 AXQ CAPITAL, LP 0.21% of their portfolio JERSEY CITY, NJ 48,06148.1k $299.4k $299.4k 0.21% First filing
78 Sculptor Capital LP 0.01% of their portfolio New York, NY 46,50046.5k $289.7k $289.7k 0.01% Unchanged
79 NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio ALBANY, NY 45,38145.4k $282.7k $282.7k 0.00% Added +2 +2
80 AMERIPRISE FINANCIAL INC 0.00% of their portfolio MINNEAPOLIS, MN 42,95143.0k $267.0k $267.0k 0.00% Added +12 +12
81 Daiwa Securities Group Inc. 0.00% of their portfolio CHIYODA-KU,TOKYO, M0 38,73538.7k $240.0k $240.0k 0.00% Reduced -25.7k -25,700
82 RAYMOND JAMES & ASSOCIATES 0.00% of their portfolio ST PETERSBURG, FL 37,92837.9k $236.3k $236.3k 0.00% New
83 Versor Investments LP 0.02% of their portfolio New York, NY 37,10037.1k $231.1k $231.1k 0.02% New
84 AMERICAN INTERNATIONAL GROUP, INC. 0.00% of their portfolio New York, NY 34,88734.9k $217.3k $217.3k 0.00% Added +3.3k +3,263
85 MetLife Investment Management, LLC 0.00% of their portfolio Whippany, NJ 34,68634.7k $216.1k $216.1k 0.00% Unchanged
86 CAXTON ASSOCIATES LP 0.01% of their portfolio NEW YORK, NY 33,23033.2k $207.0k $207.0k 0.01% New
87 DEUTSCHE BANK AG\ 0.00% of their portfolio FRANKFURT AM MAIN, 2M 32,74532.7k $204.0k $204.0k 0.00% Added +3.9k +3,927
88 PDT Partners, LLC 0.03% of their portfolio New York, NY 28,77928.8k $179.3k $179.3k 0.03% Reduced -18.4k -18,359
89 PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio BALTIMORE, MD 28,64228.6k $178.0k $178.0k 0.00% Added +1.4k +1,415
90 Invesco Ltd. 0.00% of their portfolio ATLANTA, GA 28,61028.6k $178.2k $178.2k 0.00% Reduced -467.9k -467,906
91 VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio ATLANTA, GA 28,04328.0k $174.7k $174.7k 0.00% Added +1.5k +1,514
92 MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio Toronto, A6 27,94027.9k $174.1k $174.1k 0.00% Added +1.6k +1,631
93 Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio SEOUL, M5 26,26726.3k $163.6k $163.6k 0.00% Added +204 +204
94 STIFEL FINANCIAL CORP 0.00% of their portfolio ST. LOUIS, MO 25,55725.6k $159.2k $159.2k 0.00% Reduced -4.3k -4,324
95 CFS Investment Advisory Services, LLC 0.03% of their portfolio TOTOWA, NJ 24,55124.6k $153.0k $153.0k 0.03% New
96 Legal & General Group Plc 0.00% of their portfolio London, X0 23,63023.6k $147.5k $147.5k 0.00% Added +16.0k +15,985
97 UBS Group AG 0.00% of their portfolio ZURICH, V8 23,46123.5k $146.2k $146.2k 0.00% Added +9.4k +9,377
98 Delta Financial Group, Inc. 0.06% of their portfolio BASKING RIDGE, NJ 23,35023.4k $137.0k $137.0k 0.06% First filing
99 PRINCIPAL FINANCIAL GROUP INC 0.00% of their portfolio DES MOINES, IA 20,73820.7k $129.2k $129.2k 0.00% Added +3.9k +3,882
100 BOULDER HILL CAPITAL MANAGEMENT LP 0.10% of their portfolio NEW YORK, NY 19,90019.9k $124.0k $124.0k 0.10% New