ENLIVEN THERAPEUTICS INC ELVN
COM · Common Stock · CUSIP 29337E102
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersBurlingame, CA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($195.7k this quarter). Holder counts are more reliable. Shares outstanding: 48.9m as of 2024-11-01, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $22.50. Options: 2 managers hold calls ($24.8k notional), 2 hold puts ($6.8k).
Trends to Q4 2024
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q1 2023 | 45 |
| Q2 2023 | 64 |
| Q3 2023 | 62 |
| Q4 2023 | 63 |
| Q1 2024 | 75 |
| Q2 2024 | 95 |
| Q3 2024 | 104 |
| Q4 2024 | 116 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q2 2023 | 44 | 18 |
| Q3 2023 | 28 | 30 |
| Q4 2023 | 30 | 19 |
| Q1 2024 | 42 | 24 |
| Q2 2024 | 67 | 27 |
| Q3 2024 | 59 | 33 |
| Q4 2024 | 61 | 36 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q1 2024 | $0 | $0 | — |
| Q2 2024 | $287.5k | $14.0k | 0.05 |
| Q3 2024 | $2.6k | $12.8k | 5.00 |
| Q4 2024 | $24.8k | $6.8k | 0.27 |
Biggest buyers
| Polar Capital Holdings Plc | Added | +1.7m |
| JANUS HENDERSON GROUP PLC | Added | +290.2k |
| Cormorant Asset Management, LP | New | +250.0k |
| FMR LLC | Added | +199.7k |
| Pictet Asset Management Holding SA | Added | +136.0k |
| Patient Square Capital LP | Added | +133.5k |
| FEDERATED HERMES, INC. | New | +117.6k |
| Commodore Capital LP | Added | +105.0k |
| Artia Global Partners LP | New | +102.9k |
| STEMPOINT CAPITAL LP | New | +96.7k |
Biggest sellers
| Boxer Capital, LLC | Sold out | -671.4k |
| Logos Global Management LP | Reduced | -355.0k |
| RA CAPITAL MANAGEMENT, L.P. | Reduced | -212.2k |
| Cutter Capital Management, LP | Sold out | -207.9k |
| Soleus Capital Management, L.P. | Reduced | -164.3k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | Reduced | -150.0k |
| 5AM Venture Management, LLC | Reduced | -122.4k |
| Ikarian Capital, LLC | Reduced | -105.0k |
| Walleye Capital LLC | Sold out | -99.4k |
| MARSHALL WACE, LLP | Reduced | -96.6k |
Biggest calls
| CITADEL ADVISORS LLC | Added | $24.8k1.1k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| CITADEL ADVISORS LLC | Reduced | $6.8k300 shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| FMR LLC 13G · institution +1.7 pts · filed 2026-08-06 | 15.0% |
ORBIMED ADVISORS LLC
13D · may seek influence
-1.4 pts · filed 2026-06-24
Stated purposeThe Reporting Persons from time to time intend to review their investment in the Issuer on the basis of various factors, including the Issuer's business, financial condition, results of operations and prospects, general economic and industry conditions, the securities markets in general and those for the Issuer's Shares in particular, as well as other developments and other investment opportunities. Based upon such review, the Reporting Persons will take such actions in the future as the Reporting Persons may deem appropriate in light of the circumstances existing from time to time. If the Reporting Persons believe that further investment in the Issuer is attractive, whether because of the market price of Shares or otherwise, they may acquire Shares or other securities of the Issuer either… Full filing |
9.5% |
| Polar Capital Holdings Plc 13G · institution no change · filed 2026-06-22 | 8.5% |
| Commodore Capital LP 13G · passive investor -2.2 pts · filed 2026-05-15 | 7.7% |
| BlackRock, Inc. 13G · institution +2.0 pts · filed 2026-10-27 | 7.1% |
| Vestal Point Capital, LP 13G · institution -1.1 pts · filed 2026-05-15 | 5.4% |
Fell to 5% or below in the last year: Venrock Healthcare Capital Partners III, L.P. (2.8%, 2026-05-15), Fairmount Funds Management LLC (3.1%, 2026-05-15)
Insider purchases and sales in Q4 2024
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q1 2023 | 0 | — | 2 | $199.2k | — |
| Q2 2023 | 0 | — | 0 | — | — |
| Q3 2023 | 0 | — | 2 | $329.2k | $329.2k |
| Q4 2023 | 0 | — | 5 | $1.1m | $1.0m |
| Q1 2024 | 0 | — | 6 | $2.0m | $2.0m |
| Q2 2024 | 0 | — | 9 | $30.0m | $7.1m |
| Q3 2024 | 0 | — | 5 | $3.5m | $3.5m |
| Q4 2024 | 0 | — | 7 | $4.3m | $4.3m |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2024-12-30 | Hohl Benjamin CHIEF FINANCIAL OFFICER | Sold plan | $20.3k900 shares |
| 2024-12-27 | Hohl Benjamin CHIEF FINANCIAL OFFICER | Sold plan | $74.2k3.4k shares |
| 2024-11-27 | Hohl Benjamin CHIEF FINANCIAL OFFICER | Sold plan | $130.7k5.2k shares |
| 2024-10-28 | Hohl Benjamin CHIEF FINANCIAL OFFICER | Sold plan | $178.5k6.2k shares |
| 2024-10-18 | Kintz Samuel PRESIDENT AND CEO, director · See footnote | Sold plan | $27.7k924 shares |
| 2024-10-18 | Lyssikatos Joseph P CHIEF SCIENTIFIC OFFICER · See footnote | Sold plan | $25.4k847 shares |
| 2024-10-18 | Heyman Richard A. Director | Sold plan | $24.5k817 shares |
| 2024-10-18 | Collins Helen Louise CHIEF MEDICAL OFFICER | Sold plan | $24.5k816 shares |
| 2024-10-18 | Hohl Benjamin CHIEF FINANCIAL OFFICER | Sold plan | $24.4k814 shares |
| 2024-10-18 | Heyman Richard A. Director · See footnote | Sold plan | $22.6k753 shares |
| 2024-10-18 | Patel Anish CHIEF OPERATING OFFICER · See footnote | Sold plan | $21.5k716 shares |
| 2024-10-15 | Heyman Richard A. Director | Sold plan | $35.1k1.3k shares |
| 2024-10-09 | Lyssikatos Joseph P CHIEF SCIENTIFIC OFFICER · See footnote | Sold plan | $1.1m37.9k shares |
| 2024-10-09 | Kintz Samuel PRESIDENT AND CEO, director · See footnote | Sold plan | $470.4k16.7k shares |
| 2024-10-08 | Lyssikatos Joseph P CHIEF SCIENTIFIC OFFICER · See footnote | Sold plan | $371.0k13.3k shares |
| 2024-10-08 | Kintz Samuel PRESIDENT AND CEO, director · See footnote | Sold plan | $370.9k13.3k shares |
| 2024-10-08 | Ballal Rahul D. Director | Sold plan | $293.5k10.4k shares |
| 2024-10-07 | Kintz Samuel PRESIDENT AND CEO, director · See footnote | Sold plan | $75.1k2.7k shares |
| 2024-10-07 | Lyssikatos Joseph P CHIEF SCIENTIFIC OFFICER · See footnote | Sold plan | $74.7k2.7k shares |
| 2024-10-07 | Hohl Benjamin CHIEF FINANCIAL OFFICER | Sold plan | $34.9k1.3k shares |
| 2024-10-04 | Kintz Samuel PRESIDENT AND CEO, director · See footnote | Sold plan | $335.8k12.2k shares |
| 2024-10-04 | Hohl Benjamin CHIEF FINANCIAL OFFICER | Sold plan | $281.1k10.2k shares |
| 2024-10-04 | Lyssikatos Joseph P CHIEF SCIENTIFIC OFFICER · See footnote | Sold plan | $206.9k7.5k shares |
| 2024-10-04 | Heyman Richard A. Director | Sold plan | $77.7k2.8k shares |
| 2024-10-01 | Lyssikatos Joseph P CHIEF SCIENTIFIC OFFICER · See footnote | Sold plan | $14.5k527 shares |
| 2024-10-01 | Kintz Samuel PRESIDENT AND CEO, director · See footnote | Sold plan | $14.5k526 shares |
| 2024-10-01 | Hohl Benjamin CHIEF FINANCIAL OFFICER | Sold plan | $14.3k521 shares |
| 2024-10-01 | Heyman Richard A. Director | Sold plan | $14.3k518 shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q4 2024
| Manager | Shares | Change |
|---|---|---|
| ORBIMED ADVISORS LLC 3.72% of their portfolio | 8.0m $179.1m | Unchanged |
| FMR LLC 0.01% of their portfolio | 6.5m $146.2m | Added +199.7k |
| Commodore Capital LP 6.93% of their portfolio | 4.2m $94.6m | Added +105.0k |
| Venrock Adviser, LLC 6.22% of their portfolio | 4.0m $90.6m | Unchanged |
| Fairmount Funds Management LLC 7.16% of their portfolio | 3.2m $72.1m | Unchanged |
| BlackRock, Inc. 0.00% of their portfolio | 3.0m $66.7m | Added +28.5k |
| Polar Capital Holdings Plc 0.30% of their portfolio | 2.4m $53.8m | Added +1.7m |
| VANGUARD GROUP INC 0.00% of their portfolio | 2.0m $44.5m | Added +55.3k |
| CITADEL ADVISORS LLC 0.04% of their portfolio | 1.7m $39.1m | Added +4.6k |
| 5AM Venture Management, LLC 8.75% of their portfolio | 1.6m $36.7m | Reduced -122.4k |
| JANUS HENDERSON GROUP PLC 0.02% of their portfolio | 1.3m $30.0m | Added +290.2k |
| Pictet Asset Management Holding SA 0.02% of their portfolio | 972.3k $21.9m | Added +136.0k |
| RA CAPITAL MANAGEMENT, L.P. 0.25% of their portfolio | 849.0k $19.1m | Reduced -212.2k |
| Woodline Partners LP 0.12% of their portfolio | 805.9k $18.1m | Reduced -265 |
| STATE STREET CORP 0.00% of their portfolio | 801.8k $18.0m | Added +55.9k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 762.7k $17.2m | Added +12.5k |
| Boxer Capital Management, LLC 1.29% of their portfolio | 671.4k $15.1m | First filing |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.03% of their portfolio | 650.0k $14.6m | Reduced -150.0k |
| First Turn Management, LLC 2.16% of their portfolio | 535.1k $12.0m | Unchanged |
| Rock Springs Capital Management LP 0.37% of their portfolio | 428.6k $9.6m | Unchanged |
| Ikarian Capital, LLC 2.53% of their portfolio | 394.5k $8.9m | Reduced -105.0k |
| LORD, ABBETT & CO. LLC 0.03% of their portfolio | 386.2k $8.7m | Added +65.2k |
| Blackstone Inc. 0.04% of their portfolio | 373.3k $8.4m | Unchanged |
| NORTHERN TRUST CORP 0.00% of their portfolio | 331.5k $7.5m | Added +27.1k |
| ACUTA CAPITAL PARTNERS, LLC 6.05% of their portfolio | 267.4k $6.0m | Reduced -29.0k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 261.9k $5.9m | Added +6.6k |
| Cormorant Asset Management, LP 0.31% of their portfolio | 250.0k $5.6m | New |
| Patient Square Capital LP 1.89% of their portfolio | 224.0k $5.0m | Added +133.5k |
| Nicholas Investment Partners, LP 0.31% of their portfolio | 157.6k $3.5m | Reduced -16.1k |
| Ally Bridge Group (NY) LLC 2.73% of their portfolio | 141.7k $3.2m | Reduced -93.1k |
| Logos Global Management LP 0.37% of their portfolio | 140.0k $3.1m | Reduced -355.0k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 131.2k $3.0m | Added +9.5k |
| FEDERATED HERMES, INC. 0.01% of their portfolio | 117.6k $2.6m | New |
| BAKER BROS. ADVISORS LP 0.03% of their portfolio | 114.8k $2.6m | Unchanged |
| HighVista Strategies LLC 0.94% of their portfolio | 112.5k $2.5m | Unchanged |
| MORGAN STANLEY 0.00% of their portfolio | 110.6k $2.5m | Reduced -24.8k |
| BOOTHBAY FUND MANAGEMENT, LLC 0.07% of their portfolio | 104.9k $2.4m | Reduced -27.9k |
| Nuveen Asset Management, LLC 0.00% of their portfolio | 104.0k $2.3m | Added +317 |
| Artia Global Partners LP 0.93% of their portfolio | 102.9k $2.3m | New |
| STEMPOINT CAPITAL LP 0.55% of their portfolio | 96.7k $2.2m | New |
| Bank of New York Mellon Corp 0.00% of their portfolio | 89.6k $2.0m | Reduced -828 |
| UBS Group AG 0.00% of their portfolio | 87.2k $2.0m | Added +59.5k |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 80.9k $1.8m | Added +10.7k |
| Soleus Capital Management, L.P. 0.13% of their portfolio | 75.4k $1.7m | Reduced -164.3k |
| BARCLAYS PLC 0.00% of their portfolio | 64.6k $1.5m | Added +8.3k |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 50.8k $1.1m | Added +26.4k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 50.0k $1.1m | Added +170 |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 43.7k $983.6k | Added +17.5k |
| Swiss National Bank 0.00% of their portfolio | 41.9k $942.1k | Added +5.1k |
| MARSHALL WACE, LLP 0.00% of their portfolio | 41.4k $931.1k | Reduced -96.6k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 36.8k $828.9k | Unchanged |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 35.1k $788.8k | New |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 34.2k $769.2k | Reduced -14.5k |
| Sofinnova Investments, Inc. 0.06% of their portfolio | 34.0k $765.6k | New |
| CITIGROUP INC 0.00% of their portfolio | 33.5k $754.8k | Added +4.7k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 30.5k $686.6k | Added +10.4k |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 26.8k $603.8k | Added +16.7k |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 25.0k $563.0k | Reduced -2.5k |
| Verition Fund Management LLC 0.00% of their portfolio | 24.9k $560.0k | Added +14.3k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 21.7k $489.3k | Added +1.3k |
| Legal & General Group Plc 0.00% of their portfolio | 21.1k $475.6k | Added +812 |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 20.9k $470.6k | Added +1.9k |
| FRANKLIN RESOURCES INC 0.00% of their portfolio | 20.2k $453.4k | Unchanged |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 20.0k $450.8k | Added +718 |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 19.7k $444.3k | Reduced -21.9k |
| Corebridge Financial, Inc. 0.00% of their portfolio | 17.5k $393.8k | Reduced -1.3k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 16.8k $378.8k | Reduced -446 |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 16.7k $375.0k | Added +5.5k |
| SG Americas Securities, LLC 0.00% of their portfolio | 16.6k $374.0k | Added +6.6k |
| INTECH INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 16.3k $367.2k | New |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 15.5k $349.4k | New |
| Graham Capital Management, L.P. 0.01% of their portfolio | 15.2k $341.5k | Added +6.1k |
| Invesco Ltd. 0.00% of their portfolio | 15.1k $339.1k | Added +508 |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 14.6k $328.9k | Reduced -7.5k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 13.6k $307.0k | Added +2.0k |
| Legato Capital Management LLC 0.04% of their portfolio | 13.5k $303.6k | Reduced -1.1k |
| ProShare Advisors LLC 0.00% of their portfolio | 12.2k $275.2k | Added +2.8k |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 10.7k $240.8k | Reduced -945 |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 0.00% of their portfolio | 10.5k $235.8k | Unchanged |
| China Universal Asset Management Co., Ltd. 0.02% of their portfolio | 10.4k $233.1k | Added +1.3k |
| Brevan Howard Capital Management LP 0.01% of their portfolio | 10.1k $228.2k | New |
| ExodusPoint Capital Management, LP 0.00% of their portfolio | 8.9k $200.0k | New |
| EXCHANGE TRADED CONCEPTS, LLC 0.00% of their portfolio | 7.5k $168.4k | Unchanged |
| Police & Firemen's Retirement System of New Jersey 0.00% of their portfolio | 7.1k $159.2k | First filing |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 5.0k $112.3k | New |
| KLP KAPITALFORVALTNING AS 0.00% of their portfolio | 4.3k $96.8k | First filing |
| Ameritas Investment Partners, Inc. 0.00% of their portfolio | 3.4k $77.6k | Unchanged |
| VIRTUS ADVISERS, LLC 0.03% of their portfolio | 3.1k $69.5k | Reduced -1.1k |
| Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio | 1.6k $36.4k | Reduced -80 |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 1.6k $36.0k | Added +1.1k |
| AMALGAMATED BANK 0.00% of their portfolio | 1.2k $27.0k | Unchanged |
| STRS OHIO 0.00% of their portfolio | 1.2k $27.0k | Unchanged |
| GF FUND MANAGEMENT CO. LTD. 0.00% of their portfolio | 1.0k $23.1k | First filing |
| AlphaQuest LLC 0.00% of their portfolio | 722 $16.2k | Reduced -20.4k |
| NISA INVESTMENT ADVISORS, LLC 0.00% of their portfolio | 693 $15.6k | Added +31 |
| R Squared Ltd 0.01% of their portfolio | 650 $14.6k | First filing |
| Capital Advisors, Ltd. LLC 0.00% of their portfolio | 302 $7.0k | Unchanged |
| Daiwa Securities Group Inc. 0.00% of their portfolio | 152 $3.0k | Unchanged |
| Arax Advisory Partners 0.00% of their portfolio | 103 $2.3k | Unchanged |
| Sterling Capital Management LLC 0.00% of their portfolio | 95 $2.1k | Added +55 |