CLIMB BIO INC CLYM
COM · Common Stock · CUSIP 28658R106
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersWellesley Hills, MA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Shares outstanding: 57.4m as of 2026-07-31, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $13.04. Options: 1 managers hold calls ($337.7k notional), 1 hold puts ($349.5k).
Trends to Q2 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 23 |
| Q4 2022 | 21 |
| Q1 2023 | 20 |
| Q2 2023 | 23 |
| Q3 2023 | 24 |
| Q4 2023 | 24 |
| Q1 2024 | 22 |
| Q2 2024 | 48 |
| Q3 2024 | 72 |
| Q4 2024 | 81 |
| Q1 2025 | 77 |
| Q2 2025 | 70 |
| Q3 2025 | 68 |
| Q4 2025 | 65 |
| Q1 2026 | 80 |
| Q2 2026 | 109 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2024 | 57 | 14 |
| Q4 2024 | 46 | 30 |
| Q1 2025 | 33 | 35 |
| Q2 2025 | 38 | 48 |
| Q3 2025 | 24 | 47 |
| Q4 2025 | 35 | 39 |
| Q1 2026 | 49 | 33 |
| Q2 2026 | 84 | 40 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2025 | $0 | $0 | — |
| Q4 2025 | $0 | $0 | — |
| Q1 2026 | $669.2k | $0 | 0.00 |
| Q2 2026 | $337.7k | $349.5k | 1.03 |
Biggest buyers
| FMR LLC | Added | +6.8m |
| UBS Group AG | Added | +3.3m |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | New | +2.5m |
| Cormorant Asset Management, LP | New | +2.1m |
| BlackRock, Inc. | Added | +2.0m |
| FRONTIER CAPITAL MANAGEMENT CO LLC | New | +1.9m |
| Woodline Partners LP | New | +1.6m |
| BRAIDWELL LP | Added | +1.3m |
| Redmile Group, LLC | New | +1.2m |
| CITADEL ADVISORS LLC | Added | +952.3k |
Biggest sellers
| MPM BIOIMPACT LLC | Sold out | -2.6m |
| Kynam Capital Management, LP | Sold out | -1.0m |
| MARSHALL WACE, LLP | Sold out | -773.1k |
| SILVERARC CAPITAL MANAGEMENT, LLC | Sold out | -684.9k |
| MILLENNIUM MANAGEMENT LLC | Reduced | -368.1k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | -357.1k |
| GREAT POINT PARTNERS LLC | Reduced | -334.1k |
| DIADEMA PARTNERS LP | Sold out | -286.1k |
| Longaeva Partners L.P. | Sold out | -217.8k |
| TWO SIGMA INVESTMENTS, LP | Reduced | -162.4k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $337.7k25.9k shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | New | $349.5k26.8k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
RA CAPITAL MANAGEMENT, L.P.
13D · may seek influence
no change · filed 2026-07-07
Stated purposeItem 4 of the Statement is hereby amended and supplemented as follows: On June 29, 2026 Dr. Breanna Celebi (O'Reilly), an Analyst of RA Capital, was appointed to the Board of Directors of the Issuer as the designee of RA Capital, replacing Dr. Andrew Levin, who resigned from the Board of Directors effective June 29, 2026. Full filing |
33.0% |
| FMR LLC 13G · institution new · filed 2026-07-08 | 11.9% |
| Pontifax Management 4 G.P. (2015) Ltd. 13G · passive investor new · filed 2025-09-18 | 7.7% |
| Flynn James E 13G · passive investor new · filed 2026-10-28 | 5.2% |
| BlackRock, Inc. 13G · institution new · filed 2026-10-27 | 5.0% |
Fell to 5% or below in the last year: MPM BioImpact LLC (0.0%, 2026-08-14)
Insider purchases and sales since 1 Apr 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2024 | 0 | — | 1 | $2.5k | $2.5k |
| Q1 2025 | 0 | — | 1 | $1.6k | $1.6k |
| Q2 2025 | 0 | — | 2 | $26.7k | $26.7k |
| Q3 2025 | 0 | — | 0 | — | — |
| Q4 2025 | 1 | $754.7k | 0 | — | — |
| Q1 2026 | 1 | $24.9k | 1 | $879.0k | $879.0k |
| Q2 2026 | 0 | — | 1 | $407.0k | $407.0k |
| Q3 2026 | 0 | — | 1 | $1.4m | $1.4m |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2026-09-15 | Thomas Stephen Basil Director | Sold plan | $1.4m100.0k shares |
| 2026-06-29 | Brennan Aoife President and CEO, director | Sold plan | $407.0k30.9k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2026
| Manager | Shares | Change |
|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. 1.28% of their portfolio | 11.3m $147.4m | Unchanged |
| FMR LLC 0.00% of their portfolio | 6.8m $88.5m | Added +6.8m |
| UBS Group AG 0.01% of their portfolio | 3.4m $44.4m | Added +3.3m |
| BRAIDWELL LP 1.35% of their portfolio | 2.8m $36.5m | Added +1.3m |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.05% of their portfolio | 2.5m $32.7m | New |
| BlackRock, Inc. 0.00% of their portfolio | 2.4m $30.7m | Added +2.0m |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 2.1m $27.7m | Added +210.3k |
| Cormorant Asset Management, LP 1.41% of their portfolio | 2.1m $27.5m | New |
| FRONTIER CAPITAL MANAGEMENT CO LLC 0.24% of their portfolio | 1.9m $25.3m | New |
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 1.7m $22.2m | Added +520.0k |
| Woodline Partners LP 0.06% of their portfolio | 1.6m $20.6m | New |
| CITADEL ADVISORS LLC 0.01% of their portfolio | 1.3m $16.9m | Added +952.3k |
| Redmile Group, LLC 1.07% of their portfolio | 1.2m $16.0m | New |
| GREAT POINT PARTNERS LLC 3.07% of their portfolio | 1.0m $13.0m | Reduced -334.1k |
| Affinity Asset Advisors, LLC 0.62% of their portfolio | 972.0k $12.7m | Added +272.0k |
| MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio | 908.2k $11.8m | Reduced -368.1k |
| ADAR1 Capital Management, LLC 0.50% of their portfolio | 822.6k $10.7m | Added +225.0k |
| Driehaus Capital Management LLC 0.06% of their portfolio | 790.0k $10.3m | Added +189.1k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 782.2k $10.2m | Added +469.2k |
| STEMPOINT CAPITAL LP 1.68% of their portfolio | 742.7k $9.7m | New |
| STATE STREET CORP 0.00% of their portfolio | 686.8k $9.0m | Added +554.8k |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 658.0k $8.6m | New |
| Parkman Healthcare Partners LLC 0.75% of their portfolio | 563.5k $7.3m | New |
| SUPERSTRING CAPITAL MANAGEMENT LP 4.29% of their portfolio | 521.1k $6.8m | Added +321.9k |
| SPHERA FUNDS MANAGEMENT LTD. 0.90% of their portfolio | 483.7k $6.3m | Added +64.5k |
| Invesco Ltd. 0.00% of their portfolio | 373.4k $4.9m | New |
| MORGAN STANLEY 0.00% of their portfolio | 365.1k $4.8m | Added +130.9k |
| NAN FUNG TRINITY (HK) LTD 0.46% of their portfolio | 360.7k $4.7m | Reduced -59.9k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 330.3k $4.3m | Added +202.4k |
| Ikarian Capital, LLC 0.64% of their portfolio | 300.0k $3.9m | New |
| TD Asset Management Inc 0.00% of their portfolio | 267.1k $3.5m | Added +17.0k |
| Qube Research & Technologies Ltd 0.00% of their portfolio | 266.6k $3.5m | Added +162.4k |
| Ally Bridge Group (NY) LLC 4.19% of their portfolio | 249.2k $3.2m | New |
| VANGUARD PORTFOLIO MANAGEMENT LLC 0.00% of their portfolio | 239.7k $3.1m | New |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 239.5k $3.1m | Added +135.0k |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 195.0k $2.5m | Added +36.4k |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 192.7k $2.5m | Reduced -24.6k |
| BOOTHBAY FUND MANAGEMENT, LLC 0.04% of their portfolio | 182.6k $2.4m | Added +90.3k |
| FIFTH THIRD BANCORP 0.00% of their portfolio | 164.9k $2.2m | New |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 164.7k $2.1m | Added +8.4k |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 148.2k $1.9m | Reduced -162.4k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 131.8k $1.7m | Reduced -39.6k |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.03% of their portfolio | 130.3k $1.7m | Reduced -4.0k |
| ArchPoint Investors 0.36% of their portfolio | 128.9k $1.7m | Added +7.5k |
| Schonfeld Strategic Advisors LLC 0.01% of their portfolio | 126.1k $1.6m | New |
| Bank of New York Mellon Corp 0.00% of their portfolio | 123.7k $1.6m | New |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 104.6k $1.4m | Added +82.6k |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 96.8k $1.3m | New |
| Nuveen, LLC 0.00% of their portfolio | 85.9k $1.1m | New |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 83.2k $1.1m | Reduced -66.7k |
| Cambria Investment Management, L.P. 0.05% of their portfolio | 76.1k $992.5k | New |
| XTX Topco Ltd 0.01% of their portfolio | 72.5k $944.9k | Added +20.5k |
| Informed Momentum Co LLC 0.08% of their portfolio | 69.7k $908.3k | New |
| DeepCurrents Investment Group LLC 0.03% of their portfolio | 64.3k $838.3k | New |
| ALPS ADVISORS INC 0.00% of their portfolio | 58.1k $757.9k | New |
| LPL Financial LLC 0.00% of their portfolio | 51.2k $667.3k | Reduced -9.2k |
| SEI INVESTMENTS CO 0.00% of their portfolio | 49.5k $644.9k | New |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 47.2k $616.1k | New |
| Verdad Advisers, LP 0.58% of their portfolio | 46.1k $601.3k | Reduced -98.4k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 44.5k $580.8k | New |
| OPPENHEIMER & CO INC 0.01% of their portfolio | 41.5k $541.1k | New |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 34.7k $452.1k | Added +34.7k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 31.7k $216.9k | New |
| Integrated Quantitative Investments LLC 0.07% of their portfolio | 31.4k $409.5k | New |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 30.7k $399.8k | New |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 30.3k $394.8k | Reduced -357.1k |
| D. E. Shaw & Co., Inc. 0.00% of their portfolio | 28.8k $375.6k | New |
| Virtus Investment Advisers, LLC 0.09% of their portfolio | 28.6k $373.0k | New |
| BARCLAYS PLC 0.00% of their portfolio | 26.9k $351.1k | Reduced -22.0k |
| Squarepoint Ops LLC 0.00% of their portfolio | 26.0k $338.5k | Reduced -17.0k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 25.7k $334.7k | Reduced -27.3k |
| RAYMOND JAMES FINANCIAL INC 0.00% of their portfolio | 25.2k $329.1k | Added +7.5k |
| FRANKLIN RESOURCES INC 0.00% of their portfolio | 24.6k $321.3k | New |
| MetLife Investment Management, LLC 0.00% of their portfolio | 21.3k $277.8k | New |
| CITIGROUP INC 0.00% of their portfolio | 16.5k $215.3k | Added +10.7k |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 16.2k $210.6k | New |
| STRS OHIO 0.00% of their portfolio | 15.3k $199.5k | New |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. 0.06% of their portfolio | 15.2k $198.7k | Reduced -9.3k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 14.7k $195.7k | Added +14.6k |
| State of Wyoming 0.02% of their portfolio | 14.4k $187.4k | New |
| Spark Investment Management LLC 0.35% of their portfolio | 13.6k $177.3k | New |
| BLAIR WILLIAM & CO/IL 0.00% of their portfolio | 12.7k $165.6k | Added +700 |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 12.3k $160.4k | New |
| Virtu Financial LLC 0.00% of their portfolio | 11.2k $145.0k | New |
| Susquehanna Portfolio Strategies, LLC 0.00% of their portfolio | 11.1k $144.2k | Unchanged |
| BAILARD, INC. 0.00% of their portfolio | 10.9k $142.1k | New |
| SummitTX Capital, L.P. 0.00% of their portfolio | 10.8k $140.7k | New |
| Police & Firemen's Retirement System of New Jersey 0.00% of their portfolio | 10.4k $135.5k | New |
| Vanguard Global Advisers, LLC 0.00% of their portfolio | 10.1k $131.2k | Unchanged |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 5.6k $72.6k | Reduced -23.6k |
| ACADIAN ASSET MANAGEMENT LLC 0.00% of their portfolio | 4.5k $59.0k | New |
| Legal & General Group Plc 0.00% of their portfolio | 3.4k $44.6k | New |
| Ameritas Investment Partners, Inc. 0.00% of their portfolio | 3.2k $41.7k | New |
| US BANCORP \DE\ 0.00% of their portfolio | 3.1k $40.7k | New |
| OSAIC HOLDINGS, INC. 0.00% of their portfolio | 3.1k $40.4k | Reduced -300 |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 2.9k $37.5k | Added +2.8k |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 2.2k $29.2k | Reduced -3.6k |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 1.2k $15.0k | Added +1.1k |
| Integrated Wealth Concepts LLC 0.00% of their portfolio | 1.1k $14.7k | New |
| Caitong International Asset Management Co., Ltd 0.00% of their portfolio | 886 $11.6k | New |