Vault-13

DICE THERAPEUTICS INC

COM · CUSIP 23345J104

116 institutional holders +7 vs Q4 2022
57,759,67357.8m shares reported held*
$1.7bnreported value*
19 new 44 added 32 reduced 12 sold out net bought ≈ $294.9m (+10.3m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Implied quarter-end price ≈ $28.67. Options: 6 managers hold calls ($1.5m notional), 6 hold puts ($3.7m).

Trends to Q1 2023

Institutional holders

Managers reporting a position, each quarter

050100150Q3 22: 79Q4 22: 109Q1 23: 116116Q3 22Q4 22Q1 23
Numbers
QuarterHolders
Q3 202279
Q4 2022109
Q1 2023116

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
1000100Q4 22: 82 bought or addedQ4 22: 32 cut or sold outQ4 22Q1 23: 63 bought or addedQ1 23: 44 cut or sold outQ1 23
Numbers
QuarterBought or addedCut or sold out
Q4 20228232
Q1 20236344

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$20m$40m$60mQ3 22 calls: $55.9mQ3 22 puts: $21.3mQ3 22P/C 0.38Q4 22 calls: $411.7kQ4 22 puts: $3.5mQ4 22P/C 8.50Q1 23 calls: $1.5mQ1 23 puts: $3.7mQ1 23P/C 2.55
Numbers
QuarterCallsPutsP/C
Q3 2022$55.9m$21.3m0.38
Q4 2022$411.7k$3.5m8.50
Q1 2023$1.5m$3.7m2.55

Biggest buyers

FMR LLC Added +6,163,723+6.2m
Avoro Capital Advisors LLC Added +1,424,445+1.4m
ARMISTICE CAPITAL, LLC New +1,376,000+1.4m
RA CAPITAL MANAGEMENT, L.P. Added +1,007,701+1.0m
Nicholas Investment Partners, LP New +416,151+416.2k
Woodline Partners LP Added +197,048+197.0k
BAKER BROS. ADVISORS LP Added +173,579+173.6k
BRAIDWELL LP Added +145,725+145.7k
Casdin Capital, LLC Added +145,000+145.0k
FEDERATED HERMES, INC. Added +107,847+107.8k

Biggest sellers

Balyasny Asset Management L.P. Sold out -398,477-398.5k
PERCEPTIVE ADVISORS LLC Sold out -293,362-293.4k
Logos Global Management LP Reduced -250,000-250.0k
VOLORIDGE INVESTMENT MANAGEMENT, LLC Sold out -148,194-148.2k
Deep Track Capital, LP Reduced -134,143-134.1k
D. E. Shaw & Co., Inc. Reduced -126,693-126.7k
TWO SIGMA INVESTMENTS, LP Reduced -55,390-55.4k
Informed Momentum Co LLC Sold out -53,408-53.4k
BlackRock Inc. Reduced -39,661-39.7k
Global IMC LLC Sold out -36,420-36.4k

Biggest calls

MILLENNIUM MANAGEMENT LLC New $865.0k30.2k shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP New $269.3k9.4k shares
CITADEL ADVISORS LLC Reduced $223.5k7.8k shares
SIMPLEX TRADING, LLC Reduced $54.0k1.9k shares
GROUP ONE TRADING LLC Added $51.6k1.8k shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares

Biggest puts

CITADEL ADVISORS LLC Added $1.2m41.6k shares
Caption Management, LLC Reduced $965.5k33.7k shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Added $848.0k29.6k shares
SIMPLEX TRADING, LLC Added $478.0k16.7k shares
GROUP ONE TRADING LLC Added $246.4k8.6k shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Holders, Q1 2023

#ManagerLocationShares Value% of their portfolioChangeShares change
1 FMR LLC 0.01% of their portfolio BOSTON, MA 11,361,08011.4m $325.5m $325.5m 0.01% Added +6.2m +6,163,723
2 RA CAPITAL MANAGEMENT, L.P. 5.10% of their portfolio BOSTON, MA 7,856,6127.9m $225.1m $225.1m 5.10% Added +1.0m +1,007,701
3 Avoro Capital Advisors LLC 1.68% of their portfolio NEW YORK, NY 3,950,0004.0m $113.2m $113.2m 1.68% Added +1.4m +1,424,445
4 Northpond Ventures, LLC 53.91% of their portfolio Bethesda, MD 3,292,8713.3m $94.3m $94.3m 53.91% Unchanged
5 PRICE T ROWE ASSOCIATES INC /MD/ 0.01% of their portfolio BALTIMORE, MD 3,255,4303.3m $93.3m $93.3m 0.01% Added +35.5k +35,470
6 BlackRock Inc. 0.00% of their portfolio New York, NY 3,012,4413.0m $86.3m $86.3m 0.00% Reduced -39.7k -39,661
7 Sands Capital Alternatives, LLC 19.47% of their portfolio ARLINGTON, VA 2,748,9702.7m $78.8m $78.8m 19.47% Unchanged
8 Driehaus Capital Management LLC 0.80% of their portfolio Chicago, IL 2,001,5532.0m $57.3m $57.3m 0.80% Added +47.8k +47,847
9 VANGUARD GROUP INC 0.00% of their portfolio Valley Forge, PA 1,928,2561.9m $55.2m $55.2m 0.00% Added +24.8k +24,840
10 Deep Track Capital, LP 1.95% of their portfolio GREENWICH, CT 1,600,0001.6m $45.8m $45.8m 1.95% Reduced -134.1k -134,143
11 ARMISTICE CAPITAL, LLC 0.92% of their portfolio NEW YORK, NY 1,376,0001.4m $39.4m $39.4m 0.92% New
12 Woodline Partners LP 0.48% of their portfolio San Francisco, CA 1,192,1771.2m $34.2m $34.2m 0.48% Added +197.0k +197,048
13 JANUS HENDERSON GROUP PLC 0.02% of their portfolio LONDON, X0 1,159,6641.2m $33.2m $33.2m 0.02% Added +66.2k +66,246
14 ALKEON CAPITAL MANAGEMENT LLC 0.19% of their portfolio New York, NY 1,038,1251.0m $29.7m $29.7m 0.19% Unchanged
15 BAKER BROS. ADVISORS LP 0.16% of their portfolio NEW YORK, NY 1,035,7861.0m $29.7m $29.7m 0.16% Added +173.6k +173,579
16 BRAIDWELL LP 0.93% of their portfolio STAMFORD, CT 984,800984.8k $28.2m $28.2m 0.93% Added +145.7k +145,725
17 Venrock Adviser, LLC 4.58% of their portfolio NEW YORK, NY 819,000819.0k $23.5m $23.5m 4.58% Unchanged
18 STATE STREET CORP 0.00% of their portfolio BOSTON, MA 798,284798.3k $22.9m $22.9m 0.00% Added +4.3k +4,332
19 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 695,933695.9k $19.9m $19.9m 0.00% Added +29.1k +29,107
20 D. E. Shaw & Co., Inc. 0.03% of their portfolio New York, NY 556,241556.2k $15.9m $15.9m 0.03% Reduced -126.7k -126,693
21 NOVO HOLDINGS A/S 1.10% of their portfolio HELLERUP, G7 536,100536.1k $16.7m $16.7m 1.10% Added +71.1k +71,100
22 Nicholas Investment Partners, LP 0.91% of their portfolio RANCHO SANTA FE, CA 416,151416.2k $11.9m $11.9m 0.91% New
23 ArrowMark Colorado Holdings LLC 0.13% of their portfolio Denver, CO 412,209412.2k $11.8m $11.8m 0.13% Reduced -2.6k -2,622
24 Logos Global Management LP 1.68% of their portfolio San Francisco, CA 410,000410.0k $11.7m $11.7m 1.68% Reduced -250.0k -250,000
25 New Leaf Venture Partners, L.L.C. 8.80% of their portfolio New York, NY 371,693371.7k $10.6m $10.6m 8.80% Unchanged
26 FRANKLIN RESOURCES INC 0.00% of their portfolio San Mateo, CA 336,358336.4k $9.6m $9.6m 0.00% Unchanged
27 Casdin Capital, LLC 0.73% of their portfolio New York, NY 310,000310.0k $8.9m $8.9m 0.73% Added +145.0k +145,000
28 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 308,997309.0k $8.9m $8.9m 0.00% Reduced -140 -140
29 MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio NEW YORK, NY 271,574271.6k $7.8m $7.8m 0.01% Added +61.3k +61,262
30 OUP Management Co., LLC 15.34% of their portfolio Bala Cynwyd, PA 268,346268.3k $7.7m $7.7m 15.34% Unchanged
31 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio SAN FRANCISCO, CA 255,552255.6k $7.3m $7.3m 0.00% Added +2.3k +2,275
32 Candriam S.C.A. 0.04% of their portfolio STRASSEN, N4 210,000210.0k $5.5m $5.5m 0.04% Unchanged
33 SAMSARA BIOCAPITAL, LLC 1.20% of their portfolio PALO ALTO, CA 202,773202.8k $5.8m $5.8m 1.20% Unchanged
34 CITADEL ADVISORS LLC 0.01% of their portfolio MIAMI, FL 202,092202.1k $5.8m $5.8m 0.01% Added +52.5k +52,537
35 DAFNA Capital Management LLC 1.61% of their portfolio LOS ANGELES, CA 187,585187.6k $5.4m $5.4m 1.61% Added +64.1k +64,085
36 Soleus Capital Management, L.P. 0.62% of their portfolio GREENWICH, CT 173,447173.4k $5.0m $5.0m 0.62% Unchanged
37 GOLDMAN SACHS GROUP INC 0.00% of their portfolio NEW YORK, NY 157,617157.6k $4.5m $4.5m 0.00% Reduced -13.4k -13,390
38 Nuveen Asset Management, LLC 0.00% of their portfolio CHICAGO, IL 131,429131.4k $3.8m $3.8m 0.00% Reduced -12.3k -12,310
39 Bank of New York Mellon Corp 0.00% of their portfolio NEW YORK, NY 131,384131.4k $3.8m $3.8m 0.00% Reduced -5.6k -5,598
40 FEDERATED HERMES, INC. 0.01% of their portfolio PITTSBURGH, PA 107,888107.9k $3.1m $3.1m 0.01% Added +107.8k +107,847
41 RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio NEW YORK, NY 107,500107.5k $3.1m $3.1m 0.00% Reduced -13.8k -13,800
42 Graham Capital Management, L.P. 0.09% of their portfolio ROWAYTON, CT 90,41490.4k $2.6m $2.6m 0.09% Reduced -25.9k -25,927
43 VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio ATLANTA, GA 82,90882.9k $2.4m $2.4m 0.00% Added +53.6k +53,615
44 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 77,63777.6k $2.2m $2.2m 0.00% Reduced -6.4k -6,388
45 BANK OF AMERICA CORP /DE/ 0.00% of their portfolio CHARLOTTE, NC 69,35669.4k $2.0m $2.0m 0.00% Added +39.3k +39,278
46 HighVista Strategies LLC 1.57% of their portfolio BOSTON, MA 67,35767.4k $1.9m $1.9m 1.57% Added +28.3k +28,293
47 Swiss National Bank 0.00% of their portfolio ZURICH, V8 66,90066.9k $1.9m $1.9m 0.00% Reduced -5.9k -5,900
48 KENNEDY CAPITAL MANAGEMENT LLC 0.05% of their portfolio ST LOUIS, MO 62,49762.5k $1.8m $1.8m 0.05% Added +62 +62
49 MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio Toronto, A6 61,20961.2k $1.8m $1.8m 0.00% Added +5.9k +5,900
50 TD Asset Management Inc 0.00% of their portfolio Toronto, A6 60,73960.7k $1.7m $1.7m 0.00% Unchanged
51 RHUMBLINE ADVISERS 0.00% of their portfolio BOSTON, MA 54,26554.3k $1.6m $1.6m 0.00% Added +2.7k +2,675
52 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 46,35746.4k $1.3m $1.3m 0.00% Added +8.8k +8,775
53 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio WEST SACRAMENTO, CA 40,38040.4k $1.2m $1.2m 0.00% Reduced -10 -10
54 Schonfeld Strategic Advisors LLC 0.01% of their portfolio NEW YORK, NY 39,61639.6k $1.1m $1.1m 0.01% New
55 UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio NEW YORK, NY 39,42239.4k $1.1m $1.1m 0.00% Added +9.5k +9,465
56 Squarepoint Ops LLC 0.01% of their portfolio NEW YORK, NY 38,00438.0k $1.1m $1.1m 0.01% Reduced -8.1k -8,075
57 ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio NASHVILLE, TN 32,10032.1k $919.7k $919.7k 0.00% Added +5.2k +5,200
58 Caption Management, LLC 0.19% of their portfolio OKLAHOMA CITY, OK 30,34530.3k $869.4k $869.4k 0.19% Added +8.0k +8,046
59 TUDOR INVESTMENT CORP ET AL 0.02% of their portfolio STAMFORD, CT 29,68629.7k $851.0k $851.0k 0.02% New
60 SVB FINANCIAL GROUP 1.59% of their portfolio Dallas, TX 29,06629.1k $832.7k $832.7k 1.59% Reduced -13.3k -13,292
61 Ergoteles LLC 0.03% of their portfolio NEW YORK, NY 27,14227.1k $777.6k $777.6k 0.03% New
62 STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio MADISON, WI 26,67826.7k $764.3k $764.3k 0.00% Reduced -2.9k -2,885
63 CREDIT SUISSE AG/ 0.00% of their portfolio ZURICH, V8 26,40326.4k $756.4k $756.4k 0.00% Added +8 +8
64 MARTINGALE ASSET MANAGEMENT L P 0.01% of their portfolio BOSTON, MA 24,95425.0k $714.9k $714.9k 0.01% New
65 DEUTSCHE BANK AG\ 0.00% of their portfolio FRANKFURT AM MAIN, 2M 23,69023.7k $678.7k $678.7k 0.00% Added +6.6k +6,554
66 TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio NEW YORK, NY 23,20023.2k $664.7k $664.7k 0.00% Reduced -55.4k -55,390
67 SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio BALA CYNWYD, PA 22,56422.6k $646.5k $646.5k 0.00% Added +14.4k +14,378
68 Trexquant Investment LP 0.02% of their portfolio STAMFORD, CT 21,80921.8k $624.8k $624.8k 0.02% Added +11.9k +11,931
69 BARCLAYS PLC 0.00% of their portfolio LONDON, X0 21,31621.3k $610.7k $610.7k 0.00% Added +8.2k +8,179
70 Invesco Ltd. 0.00% of their portfolio ATLANTA, GA 19,04019.0k $545.5k $545.5k 0.00% Reduced -455 -455
71 NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio ALBANY, NY 18,91518.9k $541.9k $541.9k 0.00% Reduced -3.7k -3,733
72 MetLife Investment Management, LLC 0.00% of their portfolio Whippany, NJ 18,85118.9k $540.1k $540.1k 0.00% Unchanged
73 Parkwood LLC 0.09% of their portfolio CLEVELAND, OH 17,61917.6k $505.0k $505.0k 0.09% New
74 Jump Financial, LLC 0.02% of their portfolio Chicago, IL 17,31117.3k $496.0k $496.0k 0.02% Reduced -12.3k -12,289
75 M&T Bank Corp 0.00% of their portfolio BUFFALO, NY 17,12217.1k $490.3k $490.3k 0.00% Unchanged
76 AMERICAN INTERNATIONAL GROUP, INC. 0.00% of their portfolio New York, NY 17,08117.1k $489.4k $489.4k 0.00% Added +339 +339
77 Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio SEOUL, M5 16,58516.6k $475.2k $475.2k 0.00% Reduced -30 -30
78 UBS Group AG 0.00% of their portfolio ZURICH, V8 16,14416.1k $462.5k $462.5k 0.00% Added +7.1k +7,058
79 Legal & General Group Plc 0.00% of their portfolio London, X0 15,77515.8k $452.0k $452.0k 0.00% Added +1.4k +1,437
80 JANE STREET GROUP, LLC 0.00% of their portfolio NEW YORK, NY 12,70812.7k $364.1k $364.1k 0.00% Reduced -3.4k -3,410
81 PRINCIPAL FINANCIAL GROUP INC 0.00% of their portfolio DES MOINES, IA 10,64710.6k $305.0k $305.0k 0.00% Added +1.3k +1,328
82 Versor Investments LP 0.04% of their portfolio New York, NY 10,00010.0k $286.5k $286.5k 0.04% New
83 SG Americas Securities, LLC 0.00% of their portfolio NEW YORK, NY 9,7139.7k $278.0k $278.0k 0.00% Reduced -6.9k -6,890
84 TEACHER RETIREMENT SYSTEM OF TEXAS 0.00% of their portfolio AUSTIN, TX 9,5469.5k $273.0k $273.0k 0.00% New
85 STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 0.00% of their portfolio TALLAHASSEE, FL 9,5409.5k $273.3k $273.3k 0.00% Unchanged
86 ARIZONA STATE RETIREMENT SYSTEM 0.00% of their portfolio PHOENIX, AZ 8,9789.0k $257.2k $257.2k 0.00% Added +463 +463
87 Chicago Partners Investment Group LLC 0.02% of their portfolio CHICAGO, IL 8,2978.3k $272.4k $272.4k 0.02% New
88 SIMPLEX TRADING, LLC 0.01% of their portfolio CHICAGO, IL 7,9778.0k $228.0k $228.0k 0.01% Added +4.0k +3,959
89 CM WEALTH ADVISORS LLC 0.05% of their portfolio BEACHWOOD, OH 7,7707.8k $255.0k $255.0k 0.05% New
90 ProShare Advisors LLC 0.00% of their portfolio BETHESDA, MD 7,4717.5k $214.0k $214.0k 0.00% Reduced -1.0k -1,027
91 AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio Greenwich, CT 7,3797.4k $211.4k $211.4k 0.00% New
92 Y-Intercept (Hong Kong) Ltd 0.02% of their portfolio HONG KONG, K3 7,0987.1k $203.4k $203.4k 0.02% New
93 Aigen Investment Management, LP 0.03% of their portfolio NEW YORK, NY 7,0837.1k $202.9k $202.9k 0.03% Reduced -1.1k -1,077
94 WELLS FARGO & COMPANY/MN 0.00% of their portfolio SAN FRANCISCO, CA 6,4776.5k $185.6k $185.6k 0.00% Added +6.5k +6,465
95 CITIGROUP INC 0.00% of their portfolio NEW YORK, NY 6,1556.2k $176.3k $176.3k 0.00% Reduced -256 -256
96 Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% of their portfolio ZURICH, V8 5,4265.4k $155.5k $155.5k 0.00% Added +812 +812
97 GROUP ONE TRADING LLC 0.01% of their portfolio CHICAGO, IL 5,3995.4k $154.7k $154.7k 0.01% New
98 DekaBank Deutsche Girozentrale 0.00% of their portfolio FRANKFURT, 2M 5,0005.0k $143.0k $143.0k 0.00% Unchanged
99 Artal Group S.A. 0.01% of their portfolio LUXEMBOURG, N4 4,3184.3k $124.0k $124.0k 0.01% New
100 AMALGAMATED BANK 0.00% of their portfolio NEW YORK, NY 3,7263.7k $107.0k $107.0k 0.00% Reduced -927 -927