CRINETICS PHARMACEUTICALS IN CRNX
COM · Common Stock · CUSIP 22663K107 · ISIN US22663K1079
122
institutional holders
51.6m
shares reported held*
$1.0bnreported value*
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($38.0k this quarter). Holder counts are more reliable. Implied quarter-end price ≈ $19.64. Options: 3 managers hold calls ($2.5m notional), 1 hold puts ($0).
Biggest calls
| CITADEL ADVISORS LLC | — | $2.4m123.5k shares |
| SIMPLEX TRADING, LLC | — | $80.0k4.1k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | — | $00 shares |
Biggest puts
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | — | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| FARALLON CAPITAL MANAGEMENT, L.L.C. 13G · institution filed 2026-08-03 | 8.5% |
| Farallon Capital Partners, L.P. 13G · passive investor +2.5 pts · filed 2026-02-05 | 8.5% |
| WELLINGTON MANAGEMENT GROUP LLP 13G · institution -1.0 pts · filed 2026-08-13 | 6.8% |
| DRIEHAUS CAPITAL MANAGEMENT LLC 13G · institution filed 2026-05-15 | 6.1% |
| VANGUARD CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-04-29 | 5.2% |
| PRICE T ROWE ASSOCIATES INC /MD/ 13G · institution filed 2026-05-15 | 5.1% |
Fell to 5% or below in the last year: FMR LLC (1.4%, 2026-08-07), VANGUARD GROUP INC (0.0%, 2026-03-26; now reported by VANGUARD CAPITAL MANAGEMENT LLC)
Holders, Q3 2022
| Manager | Shares | Change |
|---|---|---|
| Driehaus Capital Management LLC 1.67% of their portfolio | 5.6m $110.6m | — |
| PERCEPTIVE ADVISORS LLC 3.04% of their portfolio | 5.3m $104.5m | — |
| BlackRock Inc. 0.00% of their portfolio | 3.8m $73.7m | — |
| BVF INC/IL 2.98% of their portfolio | 3.7m $72.3m | — |
| ORBIMED ADVISORS LLC 1.17% of their portfolio | 3.2m $62.8m | — |
| FMR LLC 0.01% of their portfolio | 2.7m $52.7m | — |
| WELLINGTON MANAGEMENT GROUP LLP 0.01% of their portfolio | 2.6m $51.7m | — |
| VANGUARD GROUP INC 0.00% of their portfolio | 2.4m $46.3m | — |
| Bain Capital Life Sciences Investors, LLC 5.41% of their portfolio | 2.3m $45.3m | — |
| STATE STREET CORP 0.00% of their portfolio | 1.8m $35.5m | — |
| Frazier Life Sciences Management, L.P. 2.14% of their portfolio | 1.4m $27.8m | — |
| First Light Asset Management, LLC 2.68% of their portfolio | 1.3m $26.4m | — |
| EcoR1 Capital, LLC 0.77% of their portfolio | 1.3m $26.1m | — |
| Point72 Asset Management, L.P. 0.11% of their portfolio | 1.3m $25.7m | — |
| Deep Track Capital, LP 1.02% of their portfolio | 1.1m $20.7m | — |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 883.1k $17.3m | — |
| 5AM Venture Management, LLC 3.24% of their portfolio | 862.3k $16.9m | — |
| BAKER BROS. ADVISORS LP 0.09% of their portfolio | 735.7k $14.4m | — |
| Opaleye Management Inc. 5.44% of their portfolio | 671.3k $13.2m | — |
| NOVO HOLDINGS A/S 0.59% of their portfolio | 631.6k $12.4m | — |
| SPHERA FUNDS MANAGEMENT LTD. 2.18% of their portfolio | 626.6k $12.3m | — |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 536.1k $10.5m | — |
| Paradigm Biocapital Advisors LP 1.44% of their portfolio | 519.3k $10.2m | — |
| NORTHERN TRUST CORP 0.00% of their portfolio | 478.4k $9.4m | — |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.04% of their portfolio | 455.4k $8.9m | — |
| JANUS HENDERSON GROUP PLC 0.00% of their portfolio | 379.7k $7.5m | — |
| MPM BIOIMPACT LLC 1.70% of their portfolio | 364.7k $7.2m | — |
| Bank of New York Mellon Corp 0.00% of their portfolio | 341.5k $6.7m | — |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 336.2k $6.6m | — |
| MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio | 321.8k $6.3m | — |
| Nuveen Asset Management, LLC 0.00% of their portfolio | 296.6k $5.8m | — |
| Walleye Capital LLC 0.11% of their portfolio | 250.0k $4.9m | — |
| FIRST MANHATTAN CO. LLC. 0.01% of their portfolio | 152.2k $3.0m | — |
| SILVERARC CAPITAL MANAGEMENT, LLC 1.24% of their portfolio | 149.0k $2.9m | — |
| BANK OF MONTREAL /CAN/ 0.00% of their portfolio | 147.0k $3.1m | — |
| New Leaf Venture Partners, L.L.C. 1.64% of their portfolio | 141.0k $2.8m | — |
| Monarch Partners Asset Management LLC 0.77% of their portfolio | 130.9k $2.6m | — |
| TWO SIGMA ADVISERS, LP 0.01% of their portfolio | 128.5k $2.5m | — |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 122.7k $2.4m | — |
| MORGAN STANLEY 0.00% of their portfolio | 102.0k $2.0m | — |
| VICTORY CAPITAL MANAGEMENT INC 0.00% of their portfolio | 99.1k $1.9m | — |
| Ensign Peak Advisors, Inc 0.00% of their portfolio | 92.3k $1.8m | — |
| HighVista Strategies LLC 1.03% of their portfolio | 92.0k $1.8m | — |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) 0.02% of their portfolio | 90.5k $1.8m | — |
| Swiss National Bank 0.00% of their portfolio | 88.0k $1.7m | — |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 79.0k $1.6m | — |
| Rafferty Asset Management, LLC 0.02% of their portfolio | 75.5k $1.5m | — |
| CITIGROUP INC 0.00% of their portfolio | 70.5k $1.4m | — |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 61.6k $1.2m | — |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 59.5k $1.2m | — |
| Fisher Asset Management, LLC 0.00% of their portfolio | 53.4k $1.0m | — |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 53.0k $1.0m | — |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 51.2k $1.0m | — |
| Atom Investors LP 0.34% of their portfolio | 48.9k $961.0k | — |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 45.5k $893.3k | — |
| TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY 0.01% of their portfolio | 45.0k $884.0k | — |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 40.2k $790.0k | — |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 39.1k $769.0k | — |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 38.1k $748.0k | — |
| D. E. Shaw & Co., Inc. 0.00% of their portfolio | 37.2k $730.0k | — |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 36.3k $713.0k | — |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 32.7k $642.0k | — |
| CREDIT SUISSE AG/ 0.00% of their portfolio | 31.1k $611.0k | — |
| BIT Capital GmbH 0.11% of their portfolio | 30.2k $592.9k | — |
| ALPS ADVISORS INC 0.01% of their portfolio | 29.3k $576.0k | — |
| Jump Financial, LLC 0.02% of their portfolio | 28.5k $560.0k | — |
| MetLife Investment Management, LLC 0.00% of their portfolio | 27.3k $535.3k | — |
| TUDOR INVESTMENT CORP ET AL 0.01% of their portfolio | 26.8k $525.0k | — |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 26.1k $511.9k | — |
| AMERICAN INTERNATIONAL GROUP, INC. 0.00% of their portfolio | 25.0k $491.0k | — |
| Trexquant Investment LP 0.02% of their portfolio | 24.5k $481.0k | — |
| Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio | 23.4k $460.0k | — |
| PUTNAM INVESTMENTS LLC 0.00% of their portfolio | 23.4k $458.0k | — |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 23.3k $457.0k | — |
| Walleye Trading LLC 0.01% of their portfolio | 22.7k $445.0k | — |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 21.5k $423.0k | — |
| WESTWOOD HOLDINGS GROUP INC 0.00% of their portfolio | 21.0k $413.0k | — |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 20.6k $404.7k | — |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 20.4k $400.5k | — |
| Invesco Ltd. 0.00% of their portfolio | 18.6k $366.0k | — |
| SANDERS MORRIS HARRIS LLC 0.09% of their portfolio | 18.6k $353.0k | — |
| ALGERT GLOBAL LLC 0.02% of their portfolio | 17.4k $342.0k | — |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 0.00% of their portfolio | 17.0k $335.0k | — |
| SG Americas Securities, LLC 0.00% of their portfolio | 15.3k $301.0k | — |
| Legal & General Group Plc 0.00% of their portfolio | 15.3k $300.0k | — |
| Connacht Asset Management LP 0.56% of their portfolio | 15.1k $297.0k | — |
| TEACHER RETIREMENT SYSTEM OF TEXAS 0.00% of their portfolio | 12.3k $241.0k | — |
| NATIXIS ADVISORS, LLC 0.00% of their portfolio | 11.8k $233.0k | — |
| DekaBank Deutsche Girozentrale 0.00% of their portfolio | 11.3k $214.0k | — |
| ProShare Advisors LLC 0.00% of their portfolio | 10.3k $204.0k | — |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 10.2k $200.0k | — |
| ARIZONA STATE RETIREMENT SYSTEM 0.00% of their portfolio | 10.2k $200.0k | — |
| UBS Group AG 0.00% of their portfolio | 8.1k $160.0k | — |
| Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% of their portfolio | 7.4k $145.0k | — |
| AMALGAMATED BANK 0.00% of their portfolio | 7.0k $137.0k | — |
| VIRTUS ADVISERS, LLC 0.05% of their portfolio | 6.2k $122.0k | — |
| Ameritas Investment Partners, Inc. 0.00% of their portfolio | 4.0k $78.0k | — |
| Amundi 0.00% of their portfolio | 3.3k $61.0k | — |
| Metropolitan Life Insurance Co/NY 0.00% of their portfolio | 3.2k $62.7k | — |
| MACQUARIE GROUP LTD 0.00% of their portfolio | 3.1k $62.0k | — |