CORVUS PHARMACEUTICALS INC CRVS
COM · Common Stock · CUSIP 221015100 · ISIN US2210151005
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersSouth San Francisco, CA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($33.5k this quarter). Holder counts are more reliable. Shares outstanding: 74.7m as of 2025-11-04, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $7.70. Options: 6 managers hold calls ($4.8m notional), 8 hold puts ($5.2m).
Trends to Q4 2025
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 48 |
| Q4 2022 | 42 |
| Q1 2023 | 38 |
| Q2 2023 | 53 |
| Q3 2023 | 53 |
| Q4 2023 | 49 |
| Q1 2024 | 48 |
| Q2 2024 | 48 |
| Q3 2024 | 63 |
| Q4 2024 | 86 |
| Q1 2025 | 89 |
| Q2 2025 | 93 |
| Q3 2025 | 102 |
| Q4 2025 | 124 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q1 2024 | 18 | 21 |
| Q2 2024 | 18 | 18 |
| Q3 2024 | 35 | 12 |
| Q4 2024 | 53 | 20 |
| Q1 2025 | 40 | 35 |
| Q2 2025 | 65 | 37 |
| Q3 2025 | 56 | 30 |
| Q4 2025 | 72 | 35 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q1 2025 | $4.7m | $1.9m | 0.41 |
| Q2 2025 | $702.0k | $1.0m | 1.44 |
| Q3 2025 | $2.3m | $1.6m | 0.71 |
| Q4 2025 | $4.8m | $5.2m | 1.08 |
Biggest buyers
| MORGAN STANLEY | Added | +3.0m |
| MPM BIOIMPACT LLC | New | +2.7m |
| STATE STREET CORP | Added | +1.8m |
| DCF Advisers, LLC | New | +729.0k |
| MILLENNIUM MANAGEMENT LLC | New | +688.8k |
| Logos Global Management LP | New | +500.0k |
| ADAR1 Capital Management, LLC | New | +465.9k |
| VANGUARD GROUP INC | Added | +401.6k |
| BlackRock, Inc. | Added | +345.9k |
| JANE STREET GROUP, LLC | Added | +310.2k |
Biggest sellers
| Point72 Asset Management, L.P. | Reduced | -3.6m |
| RTW INVESTMENTS, LP | Reduced | -2.2m |
| PERCEPTIVE ADVISORS LLC | Reduced | -746.2k |
| GSA CAPITAL PARTNERS LLP | Reduced | -387.2k |
| Foresite Capital Management VI LLC | Reduced | -350.0k |
| TWO SIGMA ADVISERS, LP | Reduced | -142.7k |
| STEMPOINT CAPITAL LP | Sold out | -96.4k |
| TWO SIGMA INVESTMENTS, LP | Reduced | -59.8k |
| ROYAL BANK OF CANADA | Reduced | -59.2k |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | Reduced | -40.0k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $2.6m344.1k shares |
| CITADEL ADVISORS LLC | Added | $722.3k93.8k shares |
| SIMPLEX TRADING, LLC | Added | $485.9k63.1k shares |
| GROUP ONE TRADING LLC | Reduced | $412.7k53.6k shares |
| JANE STREET GROUP, LLC | New | $298.0k38.7k shares |
| Caption Management, LLC | New | $192.5k25.0k shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $2.0m260.2k shares |
| CITADEL ADVISORS LLC | Added | $1.3m175.0k shares |
| Caption Management, LLC | New | $815.4k105.9k shares |
| DIADEMA PARTNERS LP | Added | $408.9k53.1k shares |
| GROUP ONE TRADING LLC | Added | $256.4k33.3k shares |
| SIMPLEX TRADING, LLC | Reduced | $194.0k25.2k shares |
| JANE STREET GROUP, LLC | New | $120.9k15.7k shares |
| Persistent Asset Partners Ltd | Added | $7.5k142 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
ORBIMED ADVISORS LLC
13D · may seek influence
-1.9 pts · filed 2026-01-27
Stated purposeThe Reporting Persons from time to time intend to review their investment in the Issuer on the basis of various factors, including the Issuer's business, financial condition, results of operations and prospects, general economic and industry conditions, the securities markets in general and those for the Issuer's Shares in particular, as well as other developments and other investment opportunities. Based upon such review, the Reporting Persons will take such actions in the future as the Reporting Persons may deem appropriate in light of the circumstances existing from time to time. If the Reporting Persons believe that further investment in the Issuer is attractive, whether because of the market price of Shares or otherwise, they may acquire Shares or other securities of the Issuer eith… Full filing |
10.3% |
| MILLER RICHARD A MD 13G · exempt (held before listing) +0.1 pts · filed 2026-02-13 | 7.8% |
| BlackRock, Inc. 13G · institution +1.1 pts · filed 2026-07-27 | 7.5% |
| Sirenia Capital Management LP 13G · institution new · filed 2026-05-15 | 7.5% |
| STATE STREET CORP 13G · institution new · filed 2026-08-07 | 5.3% |
Fell to 5% or below in the last year: Point72 Asset Management, L.P. (0.0%, 2026-05-15), VANGUARD GROUP INC (0.0%, 2026-03-26), ADAMS STREET PARTNERS LLC (3.9%, 2026-02-05)
Insider purchases and sales in Q4 2025
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q1 2024 | 0 | — | 0 | — | — |
| Q2 2024 | 2 | $1.0m | 0 | — | — |
| Q3 2024 | 0 | — | 0 | — | — |
| Q4 2024 | 0 | — | 0 | — | — |
| Q1 2025 | 0 | — | 0 | — | — |
| Q2 2025 | 0 | — | 2 | $4.9m | — |
| Q3 2025 | 0 | — | 0 | — | — |
| Q4 2025 | 0 | — | 0 | — | — |
None reported in Q4 2025.
Holders, Q4 2025
| Manager | Shares | Change |
|---|---|---|
| ORBIMED ADVISORS LLC 1.13% of their portfolio | 7.2m $55.2m | Unchanged |
| BlackRock, Inc. 0.00% of their portfolio | 5.1m $38.9m | Added +345.9k |
| VANGUARD GROUP INC 0.00% of their portfolio | 3.9m $29.8m | Added +401.6k |
| MORGAN STANLEY 0.00% of their portfolio | 3.6m $27.5m | Added +3.0m |
| ADAMS STREET PARTNERS LLC 9.56% of their portfolio | 3.3m $25.2m | Unchanged |
| Point72 Asset Management, L.P. 0.03% of their portfolio | 2.9m $22.1m | Reduced -3.6m |
| STATE STREET CORP 0.00% of their portfolio | 2.8m $21.5m | Added +1.8m |
| MPM BIOIMPACT LLC 2.42% of their portfolio | 2.7m $21.1m | New |
| Vivo Capital, LLC 1.11% of their portfolio | 2.2m $17.2m | Unchanged |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 1.5m $11.3m | Added +16.5k |
| Foresite Capital Management VI LLC 3.21% of their portfolio | 1.4m $10.6m | Reduced -350.0k |
| DCF Advisers, LLC 1.85% of their portfolio | 729.0k $5.6m | New |
| PERCEPTIVE ADVISORS LLC 0.10% of their portfolio | 692.4k $5.3m | Reduced -746.2k |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 688.8k $5.3m | New |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 553.3k $4.3m | Added +107.7k |
| Logos Global Management LP 0.26% of their portfolio | 500.0k $3.9m | New |
| ADAR1 Capital Management, LLC 0.27% of their portfolio | 465.9k $3.6m | New |
| RTW INVESTMENTS, LP 0.03% of their portfolio | 447.6k $3.4m | Reduced -2.2m |
| NORTHERN TRUST CORP 0.00% of their portfolio | 429.8k $3.3m | Reduced -36.7k |
| SPHERA FUNDS MANAGEMENT LTD. 0.66% of their portfolio | 407.7k $3.1m | Unchanged |
| BARCLAYS PLC 0.00% of their portfolio | 394.8k $3.0m | Added +85.6k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 378.3k $2.9m | Added +310.2k |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 314.7k $2.4m | Added +134.5k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 236.5k $1.8m | Added +84.5k |
| MARSHALL WACE, LLP 0.00% of their portfolio | 216.2k $1.7m | New |
| UBS Group AG 0.00% of their portfolio | 212.0k $1.6m | Added +49.9k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 208.2k $1.6m | Added +165.4k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 171.2k $1.3m | Reduced -6.6k |
| Empirical Financial Services, LLC d.b.a. Empirical Wealth Management 0.02% of their portfolio | 167.4k $1.3m | Reduced -1.8k |
| FRED ALGER MANAGEMENT, LLC 0.00% of their portfolio | 144.4k $1.1m | New |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 143.6k $1.1m | Reduced -59.8k |
| TOWERVIEW LLC 0.78% of their portfolio | 140.0k $1.1m | Reduced -30.0k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 131.6k $1.0m | Added +5.1k |
| RAYMOND JAMES FINANCIAL INC 0.00% of their portfolio | 121.2k $932.9k | Reduced -3.3k |
| HSBC HOLDINGS PLC 0.00% of their portfolio | 118.5k $902.1k | Added +36.2k |
| Qube Research & Technologies Ltd 0.00% of their portfolio | 114.5k $881.6k | New |
| Squarepoint Ops LLC 0.00% of their portfolio | 104.8k $807.1k | New |
| Rafferty Asset Management, LLC 0.00% of their portfolio | 99.7k $767.9k | New |
| ExodusPoint Capital Management, LP 0.01% of their portfolio | 86.7k $667.7k | New |
| NEOS Investment Management LLC 0.00% of their portfolio | 80.9k $622.9k | Added +21.7k |
| Tema ETFs LLC 0.05% of their portfolio | 79.7k $613.7k | Added +20.5k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 70.7k $544.6k | Reduced -11.9k |
| Nuveen, LLC 0.00% of their portfolio | 68.1k $524.1k | Unchanged |
| OSAIC HOLDINGS, INC. 0.00% of their portfolio | 68.0k $523.5k | Added +1 |
| D. E. Shaw & Co., Inc. 0.00% of their portfolio | 64.9k $499.8k | Added +39.3k |
| JACKSON SQUARE CAPITAL, LLC 0.10% of their portfolio | 63.8k $491.1k | Unchanged |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 62.6k $482.2k | Added +26.2k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 61.8k $475.5k | New |
| ALPS ADVISORS INC 0.00% of their portfolio | 61.3k $472.1k | New |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 56.0k $431.5k | Added +2.4k |
| Hikari Power Ltd 0.03% of their portfolio | 50.0k $385.0k | Unchanged |
| Caption Management, LLC 0.02% of their portfolio | 49.3k $379.8k | Added +27.5k |
| Ancora Advisors LLC 0.01% of their portfolio | 47.7k $367.0k | Added +377 |
| Invesco Ltd. 0.00% of their portfolio | 43.6k $335.6k | Added +4.9k |
| Creative Planning 0.00% of their portfolio | 39.2k $301.7k | Added +13.9k |
| PROFUND ADVISORS LLC 0.01% of their portfolio | 37.1k $285.4k | New |
| INTECH INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 36.0k $277.0k | Added +9.8k |
| AlphaQuest LLC 0.02% of their portfolio | 36.0k $277.0k | New |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 34.1k $263.0k | Added +1.7k |
| AVITY INVESTMENT MANAGEMENT INC. 0.02% of their portfolio | 32.7k $251.6k | Unchanged |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 32.4k $248.3k | Added +4.9k |
| Virtus Investment Advisers, LLC 0.07% of their portfolio | 31.8k $244.7k | Added +4.9k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 30.8k $237.0k | Reduced -2.8k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 30.7k $236.0k | Reduced -33.8k |
| Argent Advisors, Inc. 0.06% of their portfolio | 30.0k $231.0k | Unchanged |
| Connor, Clark & Lunn Investment Management Ltd. 0.00% of their portfolio | 28.1k $216.5k | New |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 27.7k $213.0k | New |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 26.7k $205.6k | Reduced -40.0k |
| GROUP ONE TRADING LLC 0.01% of their portfolio | 26.7k $205.3k | New |
| Palumbo Wealth Management LLC 0.05% of their portfolio | 26.3k $202.2k | Added +2.6k |
| Balyasny Asset Management L.P. 0.00% of their portfolio | 25.0k $192.7k | Reduced -541 |
| DRW Securities, LLC 0.01% of their portfolio | 23.4k $180.1k | New |
| Three Bridge Wealth Advisors, LLC 0.05% of their portfolio | 22.4k $172.3k | Unchanged |
| Verition Fund Management LLC 0.00% of their portfolio | 21.4k $164.6k | New |
| SG Americas Securities, LLC 0.00% of their portfolio | 20.0k $154.0k | New |
| COMMERCE BANK 0.00% of their portfolio | 20.0k $154.0k | Unchanged |
| Graham Capital Management, L.P. 0.01% of their portfolio | 19.3k $148.4k | New |
| TWO SIGMA ADVISERS, LP 0.00% of their portfolio | 18.9k $145.5k | Reduced -142.7k |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 18.8k $144.8k | Unchanged |
| China Universal Asset Management Co., Ltd. 0.01% of their portfolio | 18.2k $139.9k | Added +5.1k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 17.5k $134.7k | Reduced -1.2k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 17.1k $131.8k | Unchanged |
| Sowell Financial Services LLC 0.00% of their portfolio | 17.0k $130.9k | Added +5.0k |
| SHELTON WEALTH MANAGEMENT, LLC 0.05% of their portfolio | 15.6k $120.4k | Added +1.9k |
| Police & Firemen's Retirement System of New Jersey 0.00% of their portfolio | 15.5k $119.6k | Unchanged |
| CITIGROUP INC 0.00% of their portfolio | 14.9k $114.4k | Added +10.9k |
| GSA CAPITAL PARTNERS LLP 0.01% of their portfolio | 14.2k $109.0k | Reduced -387.2k |
| ProShare Advisors LLC 0.00% of their portfolio | 13.8k $106.0k | Added +979 |
| AXQ CAPITAL, LP 0.02% of their portfolio | 12.6k $97.0k | Reduced -14.4k |
| FOX RUN MANAGEMENT, L.L.C. 0.01% of their portfolio | 11.2k $86.4k | New |
| WHITTIER TRUST CO OF NEVADA INC 0.00% of their portfolio | 11.2k $74.8k | Unchanged |
| CAPTRUST FINANCIAL ADVISORS 0.00% of their portfolio | 11.1k $85.1k | New |
| Truvestments Capital LLC 0.01% of their portfolio | 10.3k $79.0k | Added +4.7k |
| OneDigital Investment Advisors LLC 0.00% of their portfolio | 10.0k $77.0k | Unchanged |
| ROTHSCHILD INVESTMENT LLC 0.00% of their portfolio | 7.0k $53.9k | Unchanged |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 6.7k $51.3k | Unchanged |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 6.6k $50.6k | Reduced -6.0k |
| Legal & General Group Plc 0.00% of their portfolio | 5.8k $44.6k | Reduced -737 |
| Ameritas Investment Partners, Inc. 0.00% of their portfolio | 5.3k $41.2k | Unchanged |
| Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio | 3.6k $27.9k | Added +748 |