CORVUS PHARMACEUTICALS INC CRVS
COM · Common Stock · CUSIP 221015100 · ISIN US2210151005
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersSouth San Francisco, CA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($21.2k this quarter). Holder counts are more reliable. Shares outstanding: 74.7m as of 2025-11-04, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $7.37. Options: 4 managers hold calls ($2.3m notional), 7 hold puts ($1.6m).
Trends to Q3 2025
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 48 |
| Q4 2022 | 42 |
| Q1 2023 | 38 |
| Q2 2023 | 53 |
| Q3 2023 | 53 |
| Q4 2023 | 49 |
| Q1 2024 | 48 |
| Q2 2024 | 48 |
| Q3 2024 | 63 |
| Q4 2024 | 86 |
| Q1 2025 | 89 |
| Q2 2025 | 93 |
| Q3 2025 | 102 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2023 | 16 | 18 |
| Q1 2024 | 18 | 21 |
| Q2 2024 | 18 | 18 |
| Q3 2024 | 35 | 12 |
| Q4 2024 | 53 | 20 |
| Q1 2025 | 40 | 35 |
| Q2 2025 | 65 | 37 |
| Q3 2025 | 56 | 30 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q4 2024 | $15.5m | $10.1m | 0.65 |
| Q1 2025 | $4.7m | $1.9m | 0.41 |
| Q2 2025 | $702.0k | $1.0m | 1.44 |
| Q3 2025 | $2.3m | $1.6m | 0.71 |
Biggest buyers
| BlackRock, Inc. | Added | +472.0k |
| STATE STREET CORP | Added | +341.6k |
| GOLDMAN SACHS GROUP INC | Added | +275.5k |
| SPHERA FUNDS MANAGEMENT LTD. | Added | +224.6k |
| VANGUARD GROUP INC | Added | +191.2k |
| STEMPOINT CAPITAL LP | New | +96.4k |
| GEODE CAPITAL MANAGEMENT, LLC | Added | +94.8k |
| GSA CAPITAL PARTNERS LLP | Added | +82.7k |
| WELLINGTON MANAGEMENT GROUP LLP | Added | +77.8k |
| UBS Group AG | Added | +72.4k |
Biggest sellers
| DCF Advisers, LLC | Sold out | -757.5k |
| Point72 Asset Management, L.P. | Reduced | -588.1k |
| MORGAN STANLEY | Reduced | -277.2k |
| MARSHALL WACE, LLP | Sold out | -201.7k |
| ROYAL BANK OF CANADA | Reduced | -169.1k |
| RENAISSANCE TECHNOLOGIES LLC | Sold out | -165.2k |
| Squarepoint Ops LLC | Sold out | -138.5k |
| BML Capital Management, LLC | Sold out | -118.8k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Sold out | -67.8k |
| TWO SIGMA ADVISERS, LP | Reduced | -51.1k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $1.1m149.9k shares |
| GROUP ONE TRADING LLC | Added | $475.4k64.5k shares |
| CITADEL ADVISORS LLC | Added | $355.2k48.2k shares |
| SIMPLEX TRADING, LLC | Added | $346.0k47.0k shares |
Biggest puts
| CITADEL ADVISORS LLC | Added | $492.3k66.8k shares |
| DIADEMA PARTNERS LP | New | $368.5k50.0k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $325.0k44.1k shares |
| SIMPLEX TRADING, LLC | Added | $222.0k30.2k shares |
| GROUP ONE TRADING LLC | Added | $159.2k21.6k shares |
| TORONTO DOMINION BANK | New | $42.0k5.7k shares |
| Persistent Asset Partners Ltd | New | $8.3k114 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
ORBIMED ADVISORS LLC
13D · may seek influence
-1.9 pts · filed 2026-01-27
Stated purposeThe Reporting Persons from time to time intend to review their investment in the Issuer on the basis of various factors, including the Issuer's business, financial condition, results of operations and prospects, general economic and industry conditions, the securities markets in general and those for the Issuer's Shares in particular, as well as other developments and other investment opportunities. Based upon such review, the Reporting Persons will take such actions in the future as the Reporting Persons may deem appropriate in light of the circumstances existing from time to time. If the Reporting Persons believe that further investment in the Issuer is attractive, whether because of the market price of Shares or otherwise, they may acquire Shares or other securities of the Issuer eith… Full filing |
10.3% |
| MILLER RICHARD A MD 13G · exempt (held before listing) +0.1 pts · filed 2026-02-13 | 7.8% |
| BlackRock, Inc. 13G · institution +1.1 pts · filed 2026-07-27 | 7.5% |
| Sirenia Capital Management LP 13G · institution new · filed 2026-05-15 | 7.5% |
| STATE STREET CORP 13G · institution new · filed 2026-08-07 | 5.3% |
Fell to 5% or below in the last year: Point72 Asset Management, L.P. (0.0%, 2026-05-15), VANGUARD GROUP INC (0.0%, 2026-03-26), ADAMS STREET PARTNERS LLC (3.9%, 2026-02-05)
Insider purchases and sales in Q3 2025
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2023 | 0 | — | 0 | — | — |
| Q1 2024 | 0 | — | 0 | — | — |
| Q2 2024 | 2 | $1.0m | 0 | — | — |
| Q3 2024 | 0 | — | 0 | — | — |
| Q4 2024 | 0 | — | 0 | — | — |
| Q1 2025 | 0 | — | 0 | — | — |
| Q2 2025 | 0 | — | 2 | $4.9m | — |
| Q3 2025 | 0 | — | 0 | — | — |
None reported in Q3 2025.
Holders, Q3 2025
| Manager | Shares | Change |
|---|---|---|
| ORBIMED ADVISORS LLC 1.27% of their portfolio | 7.2m $52.8m | Unchanged |
| Point72 Asset Management, L.P. 0.10% of their portfolio | 6.5m $47.6m | Reduced -588.1k |
| BlackRock, Inc. 0.00% of their portfolio | 4.7m $34.7m | Added +472.0k |
| VANGUARD GROUP INC 0.00% of their portfolio | 3.5m $25.6m | Added +191.2k |
| ADAMS STREET PARTNERS LLC 15.76% of their portfolio | 3.3m $24.1m | Unchanged |
| RTW INVESTMENTS, LP 0.24% of their portfolio | 2.7m $19.7m | Unchanged |
| Vivo Capital, LLC 1.33% of their portfolio | 2.2m $16.5m | Unchanged |
| Foresite Capital Management VI LLC 4.93% of their portfolio | 1.7m $12.8m | Unchanged |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 1.5m $10.7m | Added +94.8k |
| PERCEPTIVE ADVISORS LLC 0.31% of their portfolio | 1.4m $10.6m | Unchanged |
| STATE STREET CORP 0.00% of their portfolio | 1.0m $7.4m | Added +341.6k |
| MORGAN STANLEY 0.00% of their portfolio | 617.2k $4.5m | Reduced -277.2k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 466.5k $3.4m | Added +63.3k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 445.7k $3.3m | Added +275.5k |
| SPHERA FUNDS MANAGEMENT LTD. 0.71% of their portfolio | 407.7k $3.0m | Added +224.6k |
| GSA CAPITAL PARTNERS LLP 0.25% of their portfolio | 401.4k $3.0m | Added +82.7k |
| BARCLAYS PLC 0.00% of their portfolio | 309.2k $2.3m | Reduced -34.4k |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 203.4k $1.5m | Reduced -20.6k |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 180.2k $1.3m | Added +77.8k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 177.8k $1.3m | Added +16.0k |
| TOWERVIEW LLC 0.91% of their portfolio | 170.0k $1.3m | Unchanged |
| Empirical Financial Services, LLC d.b.a. Empirical Wealth Management 0.03% of their portfolio | 169.2k $1.2m | Added +1.2k |
| UBS Group AG 0.00% of their portfolio | 162.1k $1.2m | Added +72.4k |
| TWO SIGMA ADVISERS, LP 0.00% of their portfolio | 161.6k $1.2m | Reduced -51.1k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 152.0k $1.1m | Added +19.2k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 126.5k $932.5k | Added +15.8k |
| RAYMOND JAMES FINANCIAL INC 0.00% of their portfolio | 124.5k $917.5k | Unchanged |
| STEMPOINT CAPITAL LP 0.14% of their portfolio | 96.4k $710.8k | New |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 82.6k $608.7k | Added +6.6k |
| HSBC HOLDINGS PLC 0.00% of their portfolio | 82.4k $586.6k | Reduced -1.9k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 68.1k $501.6k | Added +57.9k |
| Nuveen, LLC 0.00% of their portfolio | 68.1k $501.6k | Unchanged |
| OSAIC HOLDINGS, INC. 0.00% of their portfolio | 68.0k $390.3k | Added +670 |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.01% of their portfolio | 66.7k $491.6k | Unchanged |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 64.5k $475.1k | Added +34.0k |
| JACKSON SQUARE CAPITAL, LLC 0.10% of their portfolio | 63.8k $470.0k | Unchanged |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 60.8k $448.0k | Reduced -169.1k |
| NEOS Investment Management LLC 0.00% of their portfolio | 59.2k $436.3k | New |
| Tema ETFs LLC 0.04% of their portfolio | 59.2k $436.3k | New |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 53.6k $395.3k | Added +9.7k |
| Hikari Power Ltd 0.03% of their portfolio | 50.0k $368.0k | Unchanged |
| Ancora Advisors LLC 0.01% of their portfolio | 47.3k $348.5k | Added +4.2k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 42.8k $315.2k | New |
| Invesco Ltd. 0.00% of their portfolio | 38.7k $285.0k | Reduced -1.9k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 36.4k $268.2k | Added +9.3k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 33.6k $247.6k | Added +1.5k |
| AVITY INVESTMENT MANAGEMENT INC. 0.02% of their portfolio | 32.7k $240.9k | Unchanged |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 32.4k $239.0k | Added +6.1k |
| Argent Advisors, Inc. 0.07% of their portfolio | 30.0k $221.1k | Unchanged |
| Jain Global LLC 0.00% of their portfolio | 27.6k $203.5k | New |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 27.5k $202.9k | Reduced -1.1k |
| AXQ CAPITAL, LP 0.08% of their portfolio | 27.1k $199.4k | New |
| Virtus Investment Advisers, LLC 0.06% of their portfolio | 26.8k $197.8k | Added +4.7k |
| INTECH INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 26.2k $192.8k | Added +383 |
| D. E. Shaw & Co., Inc. 0.00% of their portfolio | 25.6k $188.5k | New |
| Balyasny Asset Management L.P. 0.00% of their portfolio | 25.6k $188.5k | New |
| Creative Planning 0.00% of their portfolio | 25.3k $186.5k | New |
| Palumbo Wealth Management LLC 0.06% of their portfolio | 23.6k $174.0k | New |
| Three Bridge Wealth Advisors, LLC 0.04% of their portfolio | 22.4k $164.9k | Unchanged |
| Caption Management, LLC 0.01% of their portfolio | 21.8k $160.9k | Unchanged |
| COMMERCE BANK 0.00% of their portfolio | 20.0k $147.4k | Unchanged |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 18.8k $138.6k | Reduced -5.0k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 18.7k $138.0k | Reduced -372 |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 17.1k $126.2k | Unchanged |
| Masso Torrence Wealth Management Inc. 0.05% of their portfolio | 17.0k $125.3k | Reduced -33.0k |
| Police & Firemen's Retirement System of New Jersey 0.00% of their portfolio | 15.5k $114.5k | Added +3.3k |
| Brevan Howard Capital Management LP 0.00% of their portfolio | 15.3k $112.8k | New |
| SHELTON WEALTH MANAGEMENT, LLC 0.05% of their portfolio | 13.7k $101.3k | New |
| China Universal Asset Management Co., Ltd. 0.01% of their portfolio | 13.1k $96.3k | Reduced -2.4k |
| ProShare Advisors LLC 0.00% of their portfolio | 12.8k $94.2k | Reduced -835 |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 12.5k $92.2k | Added +7.0k |
| Trexquant Investment LP 0.00% of their portfolio | 12.2k $90.1k | New |
| Sowell Financial Services LLC 0.00% of their portfolio | 12.0k $88.4k | Unchanged |
| WHITTIER TRUST CO OF NEVADA INC 0.00% of their portfolio | 11.2k $80.5k | Unchanged |
| PKS Advisory Services, LLC 0.02% of their portfolio | 10.5k $77.4k | Unchanged |
| OneDigital Investment Advisors LLC 0.00% of their portfolio | 10.0k $73.7k | Unchanged |
| ROTHSCHILD INVESTMENT LLC 0.00% of their portfolio | 7.0k $51.6k | Unchanged |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 6.7k $49.1k | New |
| Legal & General Group Plc 0.00% of their portfolio | 6.5k $48.1k | Added +691 |
| Truvestments Capital LLC 0.01% of their portfolio | 5.5k $40.6k | Added +738 |
| Ameritas Investment Partners, Inc. 0.00% of their portfolio | 5.3k $39.4k | Unchanged |
| CITIGROUP INC 0.00% of their portfolio | 3.9k $29.1k | Reduced -19.7k |
| Quarry LP 0.01% of their portfolio | 3.7k $26.9k | New |
| Northwest Capital Management Inc 0.03% of their portfolio | 3.4k $25.0k | Unchanged |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 3.3k $24.1k | Added +2 |
| Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio | 2.9k $21.2k | Reduced -98 |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 2.5k $18.3k | Reduced -1.7k |
| Western Pacific Wealth Management, LP 0.01% of their portfolio | 2.0k $14.7k | Unchanged |
| AMALGAMATED BANK 0.00% of their portfolio | 1.8k $13.0k | Unchanged |
| GF FUND MANAGEMENT CO. LTD. 0.00% of their portfolio | 1.6k $11.8k | Added +9 |
| FMR LLC 0.00% of their portfolio | 1.5k $10.9k | Added +1.2k |
| SBI Securities Co., Ltd. 0.00% of their portfolio | 1.0k $7.4k | Added +6 |
| Daiwa Securities Group Inc. 0.00% of their portfolio | 400 $3.0k | Unchanged |
| PNC Financial Services Group, Inc. 0.00% of their portfolio | 299 $2.2k | New |
| Physician Wealth Advisors, Inc. 0.00% of their portfolio | 177 $1.3k | New |
| Arax Advisory Partners 0.00% of their portfolio | 146 $1.1k | New |
| Sterling Capital Management LLC 0.00% of their portfolio | 144 $1.1k | Added +17 |
| GAMMA Investing LLC 0.00% of their portfolio | 94 $693 | New |
| SIGNATUREFD, LLC 0.00% of their portfolio | 76 $560 | New |
| KELLEHER FINANCIAL ADVISORS 0.00% of their portfolio | 75 $553 | New |