CORVUS PHARMACEUTICALS INC CRVS
COM · Common Stock · CUSIP 221015100 · ISIN US2210151005
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersSouth San Francisco, CA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Shares outstanding: 68.1m as of 2025-03-25, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $3.18. Options: 13 managers hold calls ($4.7m notional), 11 hold puts ($1.9m).
Trends to Q1 2025
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 48 |
| Q4 2022 | 42 |
| Q1 2023 | 38 |
| Q2 2023 | 53 |
| Q3 2023 | 53 |
| Q4 2023 | 49 |
| Q1 2024 | 48 |
| Q2 2024 | 48 |
| Q3 2024 | 63 |
| Q4 2024 | 86 |
| Q1 2025 | 89 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q2 2023 | 34 | 13 |
| Q3 2023 | 25 | 22 |
| Q4 2023 | 16 | 18 |
| Q1 2024 | 18 | 21 |
| Q2 2024 | 18 | 18 |
| Q3 2024 | 35 | 12 |
| Q4 2024 | 53 | 20 |
| Q1 2025 | 40 | 35 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q2 2024 | $111.5k | $65.2k | 0.59 |
| Q3 2024 | $6.1m | $538.1k | 0.09 |
| Q4 2024 | $15.5m | $10.1m | 0.65 |
| Q1 2025 | $4.7m | $1.9m | 0.41 |
Biggest buyers
| MILLENNIUM MANAGEMENT LLC | Added | +1.5m |
| DCF Advisers, LLC | New | +400.0k |
| TWO SIGMA INVESTMENTS, LP | Added | +278.0k |
| MORGAN STANLEY | Added | +276.2k |
| TWO SIGMA ADVISERS, LP | Added | +218.5k |
| ExodusPoint Capital Management, LP | Added | +185.8k |
| MARSHALL WACE, LLP | New | +154.8k |
| JANE STREET GROUP, LLC | Added | +142.9k |
| WELLINGTON MANAGEMENT GROUP LLP | New | +104.9k |
| HRT FINANCIAL LP | Added | +65.5k |
Biggest sellers
| SAMLYN CAPITAL, LLC | Reduced | -2.6m |
| DEERFIELD MANAGEMENT COMPANY, L.P. | Sold out | -1.0m |
| SPHERA FUNDS MANAGEMENT LTD. | Reduced | -294.6k |
| Point72 Asset Management, L.P. | Reduced | -242.4k |
| GOLDMAN SACHS GROUP INC | Reduced | -216.2k |
| RENAISSANCE TECHNOLOGIES LLC | Reduced | -125.7k |
| SIMPLEX TRADING, LLC | Reduced | -112.9k |
| Schonfeld Strategic Advisors LLC | Reduced | -89.3k |
| Engineers Gate Manager LP | Sold out | -84.6k |
| ACUTA CAPITAL PARTNERS, LLC | Sold out | -74.3k |
Biggest calls
| GOLDMAN SACHS GROUP INC | Unchanged | $1.6m500.0k shares |
| Ikarian Capital, LLC | Reduced | $1.1m338.1k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $400.4k125.9k shares |
| MILLENNIUM MANAGEMENT LLC | Reduced | $385.4k121.2k shares |
| BOOTHBAY FUND MANAGEMENT, LLC | Reduced | $311.6k98.0k shares |
| GROUP ONE TRADING LLC | Reduced | $241.7k76.0k shares |
| CITADEL ADVISORS LLC | Reduced | $224.5k70.6k shares |
| Caption Management, LLC | Reduced | $159.0k50.0k shares |
| WOLVERINE TRADING, LLC | New | $128.1k37.9k shares |
| SIMPLEX TRADING, LLC | Reduced | $125.0k39.4k shares |
Biggest puts
| SIMPLEX TRADING, LLC | Reduced | $355.0k111.8k shares |
| CITADEL ADVISORS LLC | Reduced | $332.9k104.7k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $296.4k93.2k shares |
| B Group, Inc. | Reduced | $286.2k90.0k shares |
| GROUP ONE TRADING LLC | Reduced | $212.4k66.8k shares |
| MILLENNIUM MANAGEMENT LLC | New | $159.0k50.0k shares |
| Ikarian Capital, LLC | Reduced | $159.0k50.0k shares |
| BOOTHBAY FUND MANAGEMENT, LLC | Reduced | $45.8k14.4k shares |
| WOLVERINE TRADING, LLC | New | $45.0k13.3k shares |
| JANE STREET GROUP, LLC | Reduced | $38.8k12.2k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
ORBIMED ADVISORS LLC
13D · may seek influence
-1.9 pts · filed 2026-01-27
Stated purposeThe Reporting Persons from time to time intend to review their investment in the Issuer on the basis of various factors, including the Issuer's business, financial condition, results of operations and prospects, general economic and industry conditions, the securities markets in general and those for the Issuer's Shares in particular, as well as other developments and other investment opportunities. Based upon such review, the Reporting Persons will take such actions in the future as the Reporting Persons may deem appropriate in light of the circumstances existing from time to time. If the Reporting Persons believe that further investment in the Issuer is attractive, whether because of the market price of Shares or otherwise, they may acquire Shares or other securities of the Issuer eith… Full filing |
10.3% |
| MILLER RICHARD A MD 13G · exempt (held before listing) +0.1 pts · filed 2026-02-13 | 7.8% |
| BlackRock, Inc. 13G · institution +1.1 pts · filed 2026-07-27 | 7.5% |
| Sirenia Capital Management LP 13G · institution new · filed 2026-05-15 | 7.5% |
| STATE STREET CORP 13G · institution new · filed 2026-08-07 | 5.3% |
Fell to 5% or below in the last year: Point72 Asset Management, L.P. (0.0%, 2026-05-15), VANGUARD GROUP INC (0.0%, 2026-03-26), ADAMS STREET PARTNERS LLC (3.9%, 2026-02-05)
Insider purchases and sales in Q1 2025
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q2 2023 | 1 | $24.5k | 0 | — | — |
| Q3 2023 | 0 | — | 0 | — | — |
| Q4 2023 | 0 | — | 0 | — | — |
| Q1 2024 | 0 | — | 0 | — | — |
| Q2 2024 | 2 | $1.0m | 0 | — | — |
| Q3 2024 | 0 | — | 0 | — | — |
| Q4 2024 | 0 | — | 0 | — | — |
| Q1 2025 | 0 | — | 0 | — | — |
None reported in Q1 2025.
Holders, Q1 2025
| Manager | Shares | Change |
|---|---|---|
| ORBIMED ADVISORS LLC 0.53% of their portfolio | 6.9m $22.1m | Unchanged |
| SAMLYN CAPITAL, LLC 0.21% of their portfolio | 4.1m $12.9m | Reduced -2.6m |
| ADAMS STREET PARTNERS LLC 9.22% of their portfolio | 3.3m $10.4m | Unchanged |
| Point72 Asset Management, L.P. 0.02% of their portfolio | 2.8m $8.9m | Reduced -242.4k |
| RTW INVESTMENTS, LP 0.13% of their portfolio | 2.7m $8.5m | Unchanged |
| VANGUARD GROUP INC 0.00% of their portfolio | 2.5m $7.9m | Added +39.5k |
| Vivo Capital, LLC 0.94% of their portfolio | 2.2m $7.1m | Unchanged |
| MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio | 1.6m $5.2m | Added +1.5m |
| Foresite Capital Management VI LLC 2.75% of their portfolio | 1.6m $5.0m | Unchanged |
| BlackRock, Inc. 0.00% of their portfolio | 1.1m $3.4m | Reduced -15.9k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 951.3k $3.0m | Reduced -63.7k |
| MORGAN STANLEY 0.00% of their portfolio | 673.5k $2.1m | Added +276.2k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 590.3k $1.9m | Added +23.4k |
| Qube Research & Technologies Ltd 0.00% of their portfolio | 449.1k $1.4m | Reduced -970 |
| DCF Advisers, LLC 0.68% of their portfolio | 400.0k $1.3m | New |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 368.3k $1.2m | Reduced -216.2k |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 308.4k $980.6k | Added +278.0k |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 265.0k $842.7k | Reduced -125.7k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 257.8k $819.8k | Added +142.9k |
| TWO SIGMA ADVISERS, LP 0.00% of their portfolio | 236.4k $751.8k | Added +218.5k |
| STATE STREET CORP 0.00% of their portfolio | 230.0k $731.5k | Added +24.5k |
| SPHERA FUNDS MANAGEMENT LTD. 0.16% of their portfolio | 205.9k $654.6k | Reduced -294.6k |
| ExodusPoint Capital Management, LP 0.01% of their portfolio | 199.4k $634.0k | Added +185.8k |
| MARSHALL WACE, LLP 0.00% of their portfolio | 154.8k $492.2k | New |
| TOWERVIEW LLC 0.29% of their portfolio | 127.5k $405.4k | Added +50.0k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 109.3k $347.6k | Added +3.3k |
| RAYMOND JAMES FINANCIAL INC 0.00% of their portfolio | 108.1k $343.8k | Reduced -872 |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 104.9k $333.5k | New |
| Squarepoint Ops LLC 0.00% of their portfolio | 101.0k $321.3k | Added +2.9k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 98.5k $313.4k | Added +1.6k |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 89.3k $283.9k | Added +45.5k |
| BARCLAYS PLC 0.00% of their portfolio | 83.2k $264.7k | Reduced -22.8k |
| OMERS ADMINISTRATION Corp 0.00% of their portfolio | 82.3k $261.7k | Added +6.8k |
| HRT FINANCIAL LP 0.00% of their portfolio | 81.9k $260.0k | Added +65.5k |
| OSAIC HOLDINGS, INC. 0.00% of their portfolio | 68.0k $216.2k | Unchanged |
| Graham Capital Management, L.P. 0.01% of their portfolio | 67.5k $214.8k | Added +49.2k |
| JACKSON SQUARE CAPITAL, LLC 0.07% of their portfolio | 63.8k $202.8k | Unchanged |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 61.7k $196.1k | Reduced -17.0k |
| Balyasny Asset Management L.P. 0.00% of their portfolio | 57.8k $183.9k | Added +9.5k |
| EntryPoint Capital, LLC 0.08% of their portfolio | 53.7k $170.9k | Reduced -62.9k |
| Hikari Power Ltd 0.01% of their portfolio | 50.0k $159.0k | Unchanged |
| Jain Global LLC 0.00% of their portfolio | 48.1k $153.1k | Added +31.5k |
| Jump Financial, LLC 0.00% of their portfolio | 45.0k $143.1k | New |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 41.3k $131.3k | Unchanged |
| Schonfeld Strategic Advisors LLC 0.00% of their portfolio | 39.8k $126.5k | Reduced -89.3k |
| Ancora Advisors LLC 0.00% of their portfolio | 37.9k $120.4k | Unchanged |
| Quantessence Capital LLC 0.03% of their portfolio | 36.4k $115.8k | New |
| UBS Group AG 0.00% of their portfolio | 36.4k $115.7k | Reduced -15.7k |
| Cannon Global Investment Management, LLC 0.31% of their portfolio | 35.0k $111.3k | New |
| Masso Torrence Wealth Management Inc. 0.06% of their portfolio | 35.0k $111.3k | Added +5.0k |
| AVITY INVESTMENT MANAGEMENT INC. 0.01% of their portfolio | 32.7k $103.9k | Added +3.0k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 30.0k $95.3k | Unchanged |
| LMR Partners LLP 0.00% of their portfolio | 29.9k $94.9k | New |
| SIMPLEX TRADING, LLC 0.00% of their portfolio | 27.0k $85.0k | Reduced -112.9k |
| Verition Fund Management LLC 0.00% of their portfolio | 24.4k $77.6k | New |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 22.8k $72.5k | Unchanged |
| OPPENHEIMER & CO INC 0.00% of their portfolio | 22.5k $71.7k | Added +4.5k |
| Three Bridge Wealth Advisors, LLC 0.02% of their portfolio | 22.4k $71.1k | Unchanged |
| Quinn Opportunity Partners LLC 0.00% of their portfolio | 22.3k $71.0k | Unchanged |
| Brevan Howard Capital Management LP 0.00% of their portfolio | 21.7k $69.1k | New |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) 0.00% of their portfolio | 20.9k $66.3k | Reduced -19.1k |
| Virtus Investment Advisers, LLC 0.02% of their portfolio | 20.3k $64.6k | New |
| COMMERCE BANK 0.00% of their portfolio | 20.0k $63.6k | Unchanged |
| Leonteq Securities AG 0.00% of their portfolio | 20.0k $64.4k | New |
| XTX Topco Ltd 0.00% of their portfolio | 15.0k $47.6k | Reduced -42.3k |
| Capula Management Ltd 0.00% of their portfolio | 14.8k $47.0k | Not comparable |
| China Universal Asset Management Co., Ltd. 0.00% of their portfolio | 12.9k $41.0k | Reduced -736 |
| CAPSTONE INVESTMENT ADVISORS, LLC 0.00% of their portfolio | 12.6k $40.2k | New |
| Sowell Financial Services LLC 0.00% of their portfolio | 12.0k $38.2k | New |
| GROUP ONE TRADING LLC 0.00% of their portfolio | 11.9k $37.8k | Reduced -40.9k |
| WHITTIER TRUST CO OF NEVADA INC 0.00% of their portfolio | 11.2k $35.6k | Unchanged |
| PKS Advisory Services, LLC 0.01% of their portfolio | 10.5k $33.4k | Unchanged |
| PRELUDE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 10.0k $31.9k | New |
| ROTHSCHILD INVESTMENT LLC 0.00% of their portfolio | 7.0k $22.3k | Unchanged |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 4.7k $15.1k | Reduced -19.7k |
| Northwest Capital Management Inc 0.00% of their portfolio | 3.4k $10.8k | Unchanged |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 3.0k $9.5k | Reduced -10.8k |
| Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio | 2.0k $6.9k | Reduced -93 |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 2.0k $6.4k | Added +1.8k |
| Western Pacific Wealth Management, LP 0.01% of their portfolio | 2.0k $6.4k | Unchanged |
| GF FUND MANAGEMENT CO. LTD. 0.00% of their portfolio | 1.6k $5.1k | Added +245 |
| CITIGROUP INC 0.00% of their portfolio | 1.5k $4.8k | Reduced -46.7k |
| SBI Securities Co., Ltd. 0.00% of their portfolio | 1.0k $3.2k | Unchanged |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 933 $3.0k | First filing |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 791 $2.5k | Unchanged |
| Daiwa Securities Group Inc. 0.00% of their portfolio | 400 $1.0k | New |
| Caitong International Asset Management Co., Ltd 0.00% of their portfolio | 287 $913 | Added +267 |
| FMR LLC 0.00% of their portfolio | 5 $17 | Unchanged |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. — of their portfolio | 0 $0 | Unchanged |