CONTEXT THERAPEUTICS INC CNTX
COM · Common Stock · CUSIP 21077P108
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersPhiladelphia, PA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Shares outstanding: 91.9m as of 2025-11-04, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $1.47.
Trends to Q4 2025
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 25 |
| Q4 2022 | 25 |
| Q1 2023 | 23 |
| Q2 2023 | 23 |
| Q3 2023 | 24 |
| Q4 2023 | 25 |
| Q1 2024 | 26 |
| Q2 2024 | 35 |
| Q3 2024 | 43 |
| Q4 2024 | 53 |
| Q1 2025 | 43 |
| Q2 2025 | 40 |
| Q3 2025 | 37 |
| Q4 2025 | 43 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q1 2024 | 10 | 5 |
| Q2 2024 | 26 | 12 |
| Q3 2024 | 19 | 17 |
| Q4 2024 | 27 | 16 |
| Q1 2025 | 8 | 26 |
| Q2 2025 | 13 | 15 |
| Q3 2025 | 12 | 14 |
| Q4 2025 | 16 | 12 |
Biggest buyers
| MILLENNIUM MANAGEMENT LLC | New | +2.6m |
| MARSHALL WACE, LLP | Added | +2.6m |
| VANGUARD GROUP INC | Added | +290.9k |
| RENAISSANCE TECHNOLOGIES LLC | Added | +188.2k |
| XTX Topco Ltd | Added | +91.0k |
| Point72 Asset Management, L.P. | New | +52.7k |
| Quadrature Capital Ltd | New | +46.2k |
| Corient Private Wealth LP | New | +30.2k |
| Virtu Financial LLC | New | +28.9k |
| Blue Owl Capital Holdings LP | Added | +25.0k |
Biggest sellers
| MPM BIOIMPACT LLC | Reduced | -4.0m |
| Avidity Partners Management LP | Reduced | -3.5m |
| Nantahala Capital Management, LLC | Reduced | -1.6m |
| Affinity Asset Advisors, LLC | Sold out | -402.7k |
| Qube Research & Technologies Ltd | Sold out | -82.1k |
| CITADEL ADVISORS LLC | Reduced | -69.0k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Sold out | -22.0k |
| UBS Group AG | Reduced | -6.9k |
| BlackRock, Inc. | Reduced | -924 |
| BARCLAYS PLC | Sold out | -167 |
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| Avidity Partners Management LP 13G · passive investor -1.2 pts · filed 2026-05-12 | 8.7% |
| Deep Track Capital, LP 13G · passive investor filed 2025-05-15 | 8.3% |
| Soleus Capital Master Fund, L.P. 13G · passive investor +2.4 pts · filed 2026-05-08 | 7.6% |
| BlackRock, Inc. 13G · institution new · filed 2026-07-27 | 6.7% |
Fell to 5% or below in the last year: MPM BioImpact LLC (1.4%, 2026-08-14), Blue Owl Capital Holdings LP (3.2%, 2026-08-12), Octagon Capital Advisors LP (3.3%, 2026-07-31), GREAT POINT PARTNERS LLC (2.4%, 2026-05-15)
Insider purchases and sales in Q4 2025
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q1 2024 | 0 | — | 0 | — | — |
| Q2 2024 | 0 | — | 0 | — | — |
| Q3 2024 | 0 | — | 0 | — | — |
| Q4 2024 | 0 | — | 0 | — | — |
| Q1 2025 | 0 | — | 0 | — | — |
| Q2 2025 | 3 | $107.2k | 0 | — | — |
| Q3 2025 | 0 | — | 0 | — | — |
| Q4 2025 | 0 | — | 0 | — | — |
None reported in Q4 2025.
Holders, Q4 2025
| Manager | Shares | Change |
|---|---|---|
| MPM BIOIMPACT LLC 1.80% of their portfolio | 10.7m $15.7m | Reduced -4.0m |
| Blue Owl Capital Holdings LP 3.37% of their portfolio | 7.4m $10.9m | Added +25.0k |
| Nextech Invest Ltd. 1.05% of their portfolio | 7.4m $10.9m | Unchanged |
| Deep Track Capital, LP 0.25% of their portfolio | 7.4m $10.9m | Unchanged |
| Avidity Partners Management LP 2.33% of their portfolio | 5.5m $8.1m | Reduced -3.5m |
| GREAT POINT PARTNERS LLC 2.23% of their portfolio | 4.7m $6.9m | Unchanged |
| FRANKLIN RESOURCES INC 0.00% of their portfolio | 4.0m $5.9m | Unchanged |
| VANGUARD GROUP INC 0.00% of their portfolio | 3.8m $5.6m | Added +290.9k |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 2.6m $3.8m | New |
| MARSHALL WACE, LLP 0.00% of their portfolio | 2.6m $3.8m | Added +2.6m |
| Blackstone Inc. 0.02% of their portfolio | 2.4m $3.6m | Unchanged |
| Alyeska Investment Group, L.P. 0.01% of their portfolio | 1.7m $2.4m | Unchanged |
| Sio Capital Management, LLC 0.33% of their portfolio | 1.3m $2.0m | Unchanged |
| BlackRock, Inc. 0.00% of their portfolio | 848.0k $1.2m | Reduced -924 |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 608.5k $894.9k | Reduced -115 |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 508.3k $747.2k | Added +188.2k |
| ADAR1 Capital Management, LLC 0.04% of their portfolio | 351.1k $516.1k | Unchanged |
| STATE STREET CORP 0.00% of their portfolio | 165.6k $243.4k | Added +13.0k |
| Walleye Capital LLC 0.00% of their portfolio | 132.8k $195.2k | Unchanged |
| HighTower Advisors, LLC 0.00% of their portfolio | 125.9k $185.0k | Unchanged |
| Pathstone Holdings, LLC 0.00% of their portfolio | 110.2k $162.1k | Unchanged |
| Mill Creek Capital Advisors, LLC 0.00% of their portfolio | 104.6k $153.8k | Unchanged |
| XTX Topco Ltd 0.00% of their portfolio | 101.6k $149.4k | Added +91.0k |
| Deeter Investments LLP 0.03% of their portfolio | 100.0k $147.0k | First filing |
| Velan Capital Investment Management LP 0.09% of their portfolio | 100.0k $147.0k | Unchanged |
| Clear Harbor Asset Management, LLC 0.01% of their portfolio | 92.8k $136.4k | Unchanged |
| NORTHERN TRUST CORP 0.00% of their portfolio | 84.3k $123.9k | Added +17.9k |
| Point72 Asset Management, L.P. 0.00% of their portfolio | 52.7k $77.5k | New |
| Quadrature Capital Ltd 0.00% of their portfolio | 46.2k $67.9k | New |
| Nantahala Capital Management, LLC 0.00% of their portfolio | 37.8k $55.6k | Reduced -1.6m |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 34.4k $50.5k | Reduced -69.0k |
| Corient Private Wealth LP 0.00% of their portfolio | 30.2k $44.3k | New |
| Virtu Financial LLC 0.00% of their portfolio | 28.9k $43.0k | New |
| OSAIC HOLDINGS, INC. 0.00% of their portfolio | 25.5k $37.5k | Unchanged |
| Cerity Partners LLC 0.00% of their portfolio | 20.0k $29.4k | Unchanged |
| CAXTON CORP 0.63% of their portfolio | 18.4k $27.1k | Unchanged |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 9.6k $14.1k | New |
| Strive Financial Group ,LLC 0.00% of their portfolio | 1.7k $2.5k | First filing |
| Farther Finance Advisors, LLC 0.00% of their portfolio | 1.5k $2.2k | New |
| CITIGROUP INC 0.00% of their portfolio | 1.3k $2.0k | New |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 933 $1.4k | Added +499 |
| UBS Group AG 0.00% of their portfolio | 490 $720 | Reduced -6.9k |
| SBI Securities Co., Ltd. 0.00% of their portfolio | 114 $168 | Reduced -3 |