COMPASS THERAPEUTICS INC CMPX
COM · Common Stock · CUSIP 20454B104
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersBoston, MA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Shares outstanding: 127.5m as of 2023-07-28, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $3.18.
Trends to Q2 2023
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 38 |
| Q4 2022 | 56 |
| Q1 2023 | 74 |
| Q2 2023 | 74 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 38 | 6 |
| Q1 2023 | 52 | 17 |
| Q2 2023 | 45 | 43 |
Biggest buyers
| BlackRock Inc. | Added | +4.5m |
| BRAIDWELL LP | Added | +2.7m |
| Blackstone Inc. | Added | +1.4m |
| STATE STREET CORP | Added | +1.3m |
| GEODE CAPITAL MANAGEMENT, LLC | Added | +924.6k |
| Ally Bridge Group (NY) LLC | New | +914.6k |
| NORTHERN TRUST CORP | Added | +584.6k |
| VANGUARD GROUP INC | Added | +408.6k |
| Prosight Management, LP | Added | +405.7k |
| Nuveen Asset Management, LLC | New | +391.9k |
Biggest sellers
| FMR LLC | Reduced | -5.8m |
| Foresite Capital Management V, LLC | Reduced | -2.2m |
| MILLENNIUM MANAGEMENT LLC | Reduced | -814.9k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | -757.1k |
| FRED ALGER MANAGEMENT, LLC | Sold out | -403.1k |
| JANE STREET GROUP, LLC | Sold out | -382.4k |
| Monashee Investment Management LLC | Reduced | -207.7k |
| Avidity Partners Management LP | Reduced | -204.8k |
| CAXTON CORP | Reduced | -168.3k |
| Qube Research & Technologies Ltd | Sold out | -162.6k |
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| TANG CAPITAL MANAGEMENT LLC 13G · passive investor no change · filed 2025-11-14 | 10.0% |
ORBIMED ADVISORS LLC
13D · may seek influence
-2.1 pts · filed 2025-08-15
Stated purposeThe Reporting Persons from time to time intend to review their investment in the Issuer on the basis of various factors, including the Issuer's business, financial condition, results of operations and prospects, general economic and industry conditions, the securities markets in general and those for the Issuer's Shares in particular, as well as other developments and other investment opportunities. Based upon such review, the Reporting Persons will take such actions in the future as the Reporting Persons may deem appropriate in light of the circumstances existing from time to time. If the Reporting Persons believe that further investment in the Issuer is attractive, whether because of the market price of Shares or otherwise, they may acquire Shares or other securities of the Issuer either… Full filing |
8.9% |
| SUVRETTA CAPITAL MANAGEMENT, LLC 13G · passive investor +3.0 pts · filed 2025-08-21 | 8.2% |
| STATE STREET CORP 13G · institution new · filed 2026-08-07 | 5.5% |
| BlackRock, Inc. 13G · institution +0.6 pts · filed 2026-01-21 | 5.2% |
Fell to 5% or below in the last year: Vivo Opportunity Fund Holdings, L.P. (4.0%, 2026-08-14), BIOTECHNOLOGY VALUE FUND L P (4.3%, 2026-05-15), Blackstone Holdings II L.P. (3.4%, 2026-02-13)
Insider purchases and sales in Q2 2023
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q3 2021 | 0 | — | 0 | — | — |
| Q4 2021 | 2 | $18.8m | 0 | — | — |
| Q1 2022 | 0 | — | 0 | — | — |
| Q2 2022 | 3 | $1.1m | 0 | — | — |
| Q3 2022 | 1 | $269.2k | 0 | — | — |
| Q4 2022 | 2 | $1.3m | 1 | $200.7k | — |
| Q1 2023 | 1 | $355.3k | 0 | — | — |
| Q2 2023 | 0 | — | 0 | — | — |
None reported in Q2 2023.
Holders, Q2 2023
| Manager | Shares | Change |
|---|---|---|
| ORBIMED ADVISORS LLC 1.30% of their portfolio | 22.4m $71.1m | Unchanged |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.04% of their portfolio | 6.2m $19.9m | Unchanged |
| JANUS HENDERSON GROUP PLC 0.01% of their portfolio | 6.2m $19.7m | Added +214.3k |
| BlackRock Inc. 0.00% of their portfolio | 6.0m $19.2m | Added +4.5m |
| Blackstone Inc. 0.08% of their portfolio | 6.0m $19.1m | Added +1.4m |
| BRAIDWELL LP 0.62% of their portfolio | 6.0m $18.9m | Added +2.7m |
| FMR LLC 0.00% of their portfolio | 5.5m $17.6m | Reduced -5.8m |
| Rock Springs Capital Management LP 0.42% of their portfolio | 5.5m $17.5m | Unchanged |
| VANGUARD GROUP INC 0.00% of their portfolio | 4.1m $13.0m | Added +408.6k |
| Vivo Capital, LLC 0.78% of their portfolio | 3.6m $11.3m | Unchanged |
| CHI Advisors LLC 2.73% of their portfolio | 2.8m $9.0m | Unchanged |
| Monashee Investment Management LLC 1.49% of their portfolio | 2.0m $6.3m | Reduced -207.7k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 1.8m $5.8m | Added +924.6k |
| STATE STREET CORP 0.00% of their portfolio | 1.7m $5.6m | Added +1.3m |
| Avidity Partners Management LP 0.18% of their portfolio | 1.6m $5.2m | Reduced -204.8k |
| BAKER BROS. ADVISORS LP 0.03% of their portfolio | 1.6m $5.0m | Unchanged |
| Foresite Capital Management V, LLC 3.08% of their portfolio | 1.3m $4.2m | Reduced -2.2m |
| Prosight Management, LP 1.01% of their portfolio | 1.1m $3.4m | Added +405.7k |
| Ally Bridge Group (NY) LLC 3.52% of their portfolio | 914.6k $2.9m | New |
| NORTHERN TRUST CORP 0.00% of their portfolio | 769.9k $2.4m | Added +584.6k |
| Nuveen Asset Management, LLC 0.00% of their portfolio | 391.9k $1.2m | New |
| Bank of New York Mellon Corp 0.00% of their portfolio | 271.3k $862.7k | Added +232.0k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 251.4k $799.4k | Added +208.6k |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 163.5k $519.8k | Reduced -814.9k |
| Swiss National Bank 0.00% of their portfolio | 163.4k $519.6k | Unchanged |
| MORGAN STANLEY 0.00% of their portfolio | 118.9k $378.1k | Reduced -41.2k |
| DAFNA Capital Management LLC 0.10% of their portfolio | 116.9k $371.7k | Unchanged |
| Connor, Clark & Lunn Investment Management Ltd. 0.00% of their portfolio | 115.0k $365.8k | Added +92.5k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 112.3k $357.2k | New |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 107.6k $342.0k | Reduced -91.0k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 97.1k $308.9k | Added +30.7k |
| ALPS ADVISORS INC 0.00% of their portfolio | 93.0k $295.7k | New |
| ALGERT GLOBAL LLC 0.01% of their portfolio | 88.8k $282.5k | New |
| LMR Partners LLP 0.01% of their portfolio | 80.7k $256.6k | Reduced -65.5k |
| CREDIT SUISSE AG/ 0.00% of their portfolio | 77.4k $246.2k | Added +19.3k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 75.3k $239.5k | Reduced -18.7k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 71.2k $226.3k | Added +70.8k |
| Legal & General Group Plc 0.00% of their portfolio | 66.5k $211.0k | Added +48.2k |
| UBS Group AG 0.00% of their portfolio | 62.5k $198.6k | Added +54.8k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 50.0k $158.9k | New |
| AMERICAN INTERNATIONAL GROUP, INC. 0.00% of their portfolio | 43.9k $139.7k | New |
| CAXTON CORP 0.40% of their portfolio | 43.5k $138.2k | Reduced -168.3k |
| EXCHANGE TRADED CONCEPTS, LLC 0.00% of their portfolio | 43.2k $137.4k | New |
| Invesco Ltd. 0.00% of their portfolio | 38.6k $122.9k | New |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 37.5k $119.3k | New |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 37.4k $119.0k | New |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 37.4k $118.9k | New |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 36.6k $116.5k | New |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 35.1k $111.7k | Added +33.8k |
| BARCLAYS PLC 0.00% of their portfolio | 31.9k $101.5k | Reduced -9.1k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 30.4k $96.8k | New |
| SALEM INVESTMENT COUNSELORS INC 0.00% of their portfolio | 30.0k $95.1k | Unchanged |
| CITIGROUP INC 0.00% of their portfolio | 29.1k $92.5k | Reduced -113.9k |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 0.00% of their portfolio | 25.9k $77.2k | New |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 25.5k $81.1k | Reduced -757.1k |
| Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% of their portfolio | 24.3k $77.3k | New |
| ARIZONA STATE RETIREMENT SYSTEM 0.00% of their portfolio | 21.3k $67.8k | Reduced -618 |
| TEACHER RETIREMENT SYSTEM OF TEXAS 0.00% of their portfolio | 20.6k $65.0k | Reduced -2.7k |
| STRS OHIO 0.00% of their portfolio | 19.0k $60.0k | New |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 18.5k $59.0k | New |
| STIFEL FINANCIAL CORP 0.00% of their portfolio | 15.0k $47.7k | New |
| B. Riley Wealth Advisors, Inc. 0.00% of their portfolio | 14.9k $47.4k | Unchanged |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 12.8k $41.0k | Added +11.8k |
| ProShare Advisors LLC 0.00% of their portfolio | 11.9k $37.7k | New |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 11.6k $34.6k | Reduced -58.3k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 11.3k $35.8k | New |
| FLAGSHIP HARBOR ADVISORS, LLC 0.00% of their portfolio | 11.0k $35.0k | Reduced -500 |
| XTX Topco Ltd 0.01% of their portfolio | 11.0k $35.0k | New |
| AMALGAMATED BANK 0.00% of their portfolio | 9.4k $30.0k | New |
| Ameritas Investment Partners, Inc. 0.00% of their portfolio | 7.5k $24.0k | New |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 6.7k $21.4k | Reduced -1.1k |
| Metropolitan Life Insurance Co/NY 0.00% of their portfolio | 5.2k $16.5k | New |
| Aquatic Capital Management LLC 0.00% of their portfolio | 100 $0 | New |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. 0.00% of their portfolio | 0 $0 | Unchanged |