Vault-13

COMPASS THERAPEUTICS INC CMPX

COM · Common Stock · CUSIP 20454B104

74 institutional holders +0 vs Q1 2023
90,479,07290.5m shares reported held*
71.0% of all shares outstanding*
$287.7mreported value*
26 new 19 added 18 reduced 25 sold out net bought ≈ $10.5m (+3.3m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Shares outstanding: 127.5m as of 2023-07-28, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $3.18.

Trends to Q2 2023

Institutional holders

Managers reporting a position, each quarter

0255075Q3 22: 38Q4 22: 56Q1 23: 74Q2 23: 7474Q3 22Q4 22Q1 23Q2 23
Numbers
QuarterHolders
Q3 202238
Q4 202256
Q1 202374
Q2 202374

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
1000100Q4 22: 38 bought or addedQ4 22: 6 cut or sold outQ4 22Q1 23: 52 bought or addedQ1 23: 17 cut or sold outQ1 23Q2 23: 45 bought or addedQ2 23: 43 cut or sold outQ2 23
Numbers
QuarterBought or addedCut or sold out
Q4 2022386
Q1 20235217
Q2 20234543

Biggest buyers

BlackRock Inc. Added +4,491,397+4.5m
BRAIDWELL LP Added +2,706,426+2.7m
Blackstone Inc. Added +1,379,742+1.4m
STATE STREET CORP Added +1,344,201+1.3m
GEODE CAPITAL MANAGEMENT, LLC Added +924,644+924.6k
Ally Bridge Group (NY) LLC New +914,630+914.6k
NORTHERN TRUST CORP Added +584,562+584.6k
VANGUARD GROUP INC Added +408,556+408.6k
Prosight Management, LP Added +405,697+405.7k
Nuveen Asset Management, LLC New +391,871+391.9k

Biggest sellers

FMR LLC Reduced -5,826,638-5.8m
Foresite Capital Management V, LLC Reduced -2,156,652-2.2m
MILLENNIUM MANAGEMENT LLC Reduced -814,937-814.9k
SUSQUEHANNA INTERNATIONAL GROUP, LLP Reduced -757,110-757.1k
FRED ALGER MANAGEMENT, LLC Sold out -403,062-403.1k
JANE STREET GROUP, LLC Sold out -382,385-382.4k
Monashee Investment Management LLC Reduced -207,746-207.7k
Avidity Partners Management LP Reduced -204,800-204.8k
CAXTON CORP Reduced -168,274-168.3k
Qube Research & Technologies Ltd Sold out -162,624-162.6k

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
TANG CAPITAL MANAGEMENT LLC 13G · passive investor no change · filed 2025-11-14 10.0% no change 17.2m≈ $37.6m 2025-11-14
ORBIMED ADVISORS LLC 13D · may seek influence -2.1 pts · filed 2025-08-15
Stated purposeThe Reporting Persons from time to time intend to review their investment in the Issuer on the basis of various factors, including the Issuer's business, financial condition, results of operations and prospects, general economic and industry conditions, the securities markets in general and those for the Issuer's Shares in particular, as well as other developments and other investment opportunities. Based upon such review, the Reporting Persons will take such actions in the future as the Reporting Persons may deem appropriate in light of the circumstances existing from time to time. If the Reporting Persons believe that further investment in the Issuer is attractive, whether because of the market price of Shares or otherwise, they may acquire Shares or other securities of the Issuer either… Full filing
8.9% -2.1 pts 15.2m≈ $33.3m 2025-08-15
SUVRETTA CAPITAL MANAGEMENT, LLC 13G · passive investor +3.0 pts · filed 2025-08-21 8.2% +3.0 pts 14.1m≈ $30.9m 2025-08-21
STATE STREET CORP 13G · institution new · filed 2026-08-07 5.5% new 10.0m≈ $21.8m 2026-08-07
BlackRock, Inc. 13G · institution +0.6 pts · filed 2026-01-21 5.2% +0.6 pts 9.3m≈ $20.3m 2026-01-21

Fell to 5% or below in the last year: Vivo Opportunity Fund Holdings, L.P. (4.0%, 2026-08-14), BIOTECHNOLOGY VALUE FUND L P (4.3%, 2026-05-15), Blackstone Holdings II L.P. (3.4%, 2026-02-13)

Insider purchases and sales in Q2 2023

Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.

Officers and directors buying vs selling

Number of people, by quarter (10% owners not included)

BuyingSelling
404Q3 21: 0 buyingQ3 21: 0 sellingQ4 21: 2 buyingQ4 21: 0 sellingQ4 21Q1 22: 0 buyingQ1 22: 0 sellingQ2 22: 3 buyingQ2 22: 0 sellingQ2 22Q3 22: 1 buyingQ3 22: 0 sellingQ4 22: 2 buyingQ4 22: 1 sellingQ4 22Q1 23: 1 buyingQ1 23: 0 sellingQ2 23: 0 buyingQ2 23: 0 sellingQ2 23
Numbers
QuarterBuyingBoughtSellingSoldSold under a plan
Q3 20210—0——
Q4 20212$18.8m0——
Q1 20220—0——
Q2 20223$1.1m0——
Q3 20221$269.2k0——
Q4 20222$1.3m1$200.7k—
Q1 20231$355.3k0——
Q2 20230—0——

None reported in Q2 2023.

Holders, Q2 2023

#ManagerLocationShares Value% of their portfolioChangeShares change
1 ORBIMED ADVISORS LLC 1.30% of their portfolio New York, NY 22,362,85022.4m $71.1m $71.1m 1.30% Unchanged
2 ADAGE CAPITAL PARTNERS GP, L.L.C. 0.04% of their portfolio Boston, MA 6,250,0006.2m $19.9m $19.9m 0.04% Unchanged
3 JANUS HENDERSON GROUP PLC 0.01% of their portfolio LONDON, X0 6,218,7416.2m $19.7m $19.7m 0.01% Added +214.3k +214,268
4 BlackRock Inc. 0.00% of their portfolio New York, NY 6,032,2926.0m $19.2m $19.2m 0.00% Added +4.5m +4,491,397
5 Blackstone Inc. 0.08% of their portfolio NEW YORK, NY 6,000,7406.0m $19.1m $19.1m 0.08% Added +1.4m +1,379,742
6 BRAIDWELL LP 0.62% of their portfolio STAMFORD, CT 5,954,2736.0m $18.9m $18.9m 0.62% Added +2.7m +2,706,426
7 FMR LLC 0.00% of their portfolio BOSTON, MA 5,535,5065.5m $17.6m $17.6m 0.00% Reduced -5.8m -5,826,638
8 Rock Springs Capital Management LP 0.42% of their portfolio Baltimore, MD 5,513,7885.5m $17.5m $17.5m 0.42% Unchanged
9 VANGUARD GROUP INC 0.00% of their portfolio Valley Forge, PA 4,097,8824.1m $13.0m $13.0m 0.00% Added +408.6k +408,556
10 Vivo Capital, LLC 0.78% of their portfolio Palo Alto, CA 3,556,0233.6m $11.3m $11.3m 0.78% Unchanged
11 CHI Advisors LLC 2.73% of their portfolio NEW YORK, NY 2,829,7122.8m $9.0m $9.0m 2.73% Unchanged
12 Monashee Investment Management LLC 1.49% of their portfolio Boston, MA 1,969,2962.0m $6.3m $6.3m 1.49% Reduced -207.7k -207,746
13 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 1,808,2071.8m $5.8m $5.8m 0.00% Added +924.6k +924,644
14 STATE STREET CORP 0.00% of their portfolio BOSTON, MA 1,746,5141.7m $5.6m $5.6m 0.00% Added +1.3m +1,344,201
15 Avidity Partners Management LP 0.18% of their portfolio DALLAS, TX 1,620,2001.6m $5.2m $5.2m 0.18% Reduced -204.8k -204,800
16 BAKER BROS. ADVISORS LP 0.03% of their portfolio NEW YORK, NY 1,557,6301.6m $5.0m $5.0m 0.03% Unchanged
17 Foresite Capital Management V, LLC 3.08% of their portfolio WEST HOLLYWOOD, CA 1,324,0711.3m $4.2m $4.2m 3.08% Reduced -2.2m -2,156,652
18 Prosight Management, LP 1.01% of their portfolio DALLAS, TX 1,083,9971.1m $3.4m $3.4m 1.01% Added +405.7k +405,697
19 Ally Bridge Group (NY) LLC 3.52% of their portfolio NEW YORK, NY 914,630914.6k $2.9m $2.9m 3.52% New
20 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 769,865769.9k $2.4m $2.4m 0.00% Added +584.6k +584,562
21 Nuveen Asset Management, LLC 0.00% of their portfolio CHICAGO, IL 391,871391.9k $1.2m $1.2m 0.00% New
22 Bank of New York Mellon Corp 0.00% of their portfolio NEW YORK, NY 271,296271.3k $862.7k $862.7k 0.00% Added +232.0k +231,990
23 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio SAN FRANCISCO, CA 251,396251.4k $799.4k $799.4k 0.00% Added +208.6k +208,629
24 MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio NEW YORK, NY 163,466163.5k $519.8k $519.8k 0.00% Reduced -814.9k -814,937
25 Swiss National Bank 0.00% of their portfolio ZURICH, V8 163,400163.4k $519.6k $519.6k 0.00% Unchanged
26 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 118,896118.9k $378.1k $378.1k 0.00% Reduced -41.2k -41,168
27 DAFNA Capital Management LLC 0.10% of their portfolio LOS ANGELES, CA 116,882116.9k $371.7k $371.7k 0.10% Unchanged
28 Connor, Clark & Lunn Investment Management Ltd. 0.00% of their portfolio VANCOUVER, A1 115,046115.0k $365.8k $365.8k 0.00% Added +92.5k +92,495
29 RHUMBLINE ADVISERS 0.00% of their portfolio BOSTON, MA 112,328112.3k $357.2k $357.2k 0.00% New
30 GOLDMAN SACHS GROUP INC 0.00% of their portfolio NEW YORK, NY 107,556107.6k $342.0k $342.0k 0.00% Reduced -91.0k -90,966
31 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio WEST SACRAMENTO, CA 97,12497.1k $308.9k $308.9k 0.00% Added +30.7k +30,732
32 ALPS ADVISORS INC 0.00% of their portfolio Denver, CO 92,98893.0k $295.7k $295.7k 0.00% New
33 ALGERT GLOBAL LLC 0.01% of their portfolio SAN FRANCISCO, CA 88,83388.8k $282.5k $282.5k 0.01% New
34 LMR Partners LLP 0.01% of their portfolio LONDON, X0 80,69280.7k $256.6k $256.6k 0.01% Reduced -65.5k -65,481
35 CREDIT SUISSE AG/ 0.00% of their portfolio ZURICH, V8 77,42477.4k $246.2k $246.2k 0.00% Added +19.3k +19,265
36 BANK OF AMERICA CORP /DE/ 0.00% of their portfolio CHARLOTTE, NC 75,31475.3k $239.5k $239.5k 0.00% Reduced -18.7k -18,666
37 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 71,16471.2k $226.3k $226.3k 0.00% Added +70.8k +70,757
38 Legal & General Group Plc 0.00% of their portfolio London, X0 66,49966.5k $211.0k $211.0k 0.00% Added +48.2k +48,231
39 UBS Group AG 0.00% of their portfolio ZURICH, V8 62,46262.5k $198.6k $198.6k 0.00% Added +54.8k +54,780
40 MetLife Investment Management, LLC 0.00% of their portfolio Whippany, NJ 49,95350.0k $158.9k $158.9k 0.00% New
41 AMERICAN INTERNATIONAL GROUP, INC. 0.00% of their portfolio New York, NY 43,92443.9k $139.7k $139.7k 0.00% New
42 CAXTON CORP 0.40% of their portfolio Princeton, NJ 43,46643.5k $138.2k $138.2k 0.40% Reduced -168.3k -168,274
43 EXCHANGE TRADED CONCEPTS, LLC 0.00% of their portfolio Oklahoma City, OK 43,20543.2k $137.4k $137.4k 0.00% New
44 Invesco Ltd. 0.00% of their portfolio ATLANTA, GA 38,64438.6k $122.9k $122.9k 0.00% New
45 MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio Toronto, A6 37,52037.5k $119.3k $119.3k 0.00% New
46 VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio ATLANTA, GA 37,43337.4k $119.0k $119.0k 0.00% New
47 NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio ALBANY, NY 37,40037.4k $118.9k $118.9k 0.00% New
48 DEUTSCHE BANK AG\ 0.00% of their portfolio FRANKFURT AM MAIN, 2M 36,63836.6k $116.5k $116.5k 0.00% New
49 WELLS FARGO & COMPANY/MN 0.00% of their portfolio SAN FRANCISCO, CA 35,12035.1k $111.7k $111.7k 0.00% Added +33.8k +33,783
50 BARCLAYS PLC 0.00% of their portfolio LONDON, X0 31,92131.9k $101.5k $101.5k 0.00% Reduced -9.1k -9,065
51 DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio AUSTIN, TX 30,45030.4k $96.8k $96.8k 0.00% New
52 SALEM INVESTMENT COUNSELORS INC 0.00% of their portfolio WINSTON-SALEM, NC 30,00030.0k $95.1k $95.1k 0.00% Unchanged
53 CITIGROUP INC 0.00% of their portfolio NEW YORK, NY 29,08829.1k $92.5k $92.5k 0.00% Reduced -113.9k -113,853
54 STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 0.00% of their portfolio TALLAHASSEE, FL 25,91025.9k $77.2k $77.2k 0.00% New
55 SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio BALA CYNWYD, PA 25,50725.5k $81.1k $81.1k 0.00% Reduced -757.1k -757,110
56 Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% of their portfolio ZURICH, V8 24,31424.3k $77.3k $77.3k 0.00% New
57 ARIZONA STATE RETIREMENT SYSTEM 0.00% of their portfolio PHOENIX, AZ 21,32021.3k $67.8k $67.8k 0.00% Reduced -618 -618
58 TEACHER RETIREMENT SYSTEM OF TEXAS 0.00% of their portfolio AUSTIN, TX 20,59220.6k $65.0k $65.0k 0.00% Reduced -2.7k -2,733
59 STRS OHIO 0.00% of their portfolio COLUMBUS, OH 19,00019.0k $60.0k $60.0k 0.00% New
60 PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio BALTIMORE, MD 18,52118.5k $59.0k $59.0k 0.00% New
61 STIFEL FINANCIAL CORP 0.00% of their portfolio ST. LOUIS, MO 15,00015.0k $47.7k $47.7k 0.00% New
62 B. Riley Wealth Advisors, Inc. 0.00% of their portfolio MEMPHIS, TN 14,91814.9k $47.4k $47.4k 0.00% Unchanged
63 ROYAL BANK OF CANADA 0.00% of their portfolio TORONTO, A6 12,75012.8k $41.0k $41.0k 0.00% Added +11.8k +11,793
64 ProShare Advisors LLC 0.00% of their portfolio BETHESDA, MD 11,86811.9k $37.7k $37.7k 0.00% New
65 STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio MADISON, WI 11,60111.6k $34.6k $34.6k 0.00% Reduced -58.3k -58,255
66 ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio NASHVILLE, TN 11,26011.3k $35.8k $35.8k 0.00% New
67 FLAGSHIP HARBOR ADVISORS, LLC 0.00% of their portfolio BOSTON, MA 11,00011.0k $35.0k $35.0k 0.00% Reduced -500 -500
68 XTX Topco Ltd 0.01% of their portfolio LONDON, X0 10,99211.0k $35.0k $35.0k 0.01% New
69 AMALGAMATED BANK 0.00% of their portfolio NEW YORK, NY 9,3779.4k $30.0k $30.0k 0.00% New
70 Ameritas Investment Partners, Inc. 0.00% of their portfolio LINCOLN, NE 7,5367.5k $24.0k $24.0k 0.00% New
71 Tower Research Capital LLC (TRC) 0.00% of their portfolio NEW YORK, NY 6,7146.7k $21.4k $21.4k 0.00% Reduced -1.1k -1,141
72 Metropolitan Life Insurance Co/NY 0.00% of their portfolio New York, NY 5,1765.2k $16.5k $16.5k 0.00% New
73 Aquatic Capital Management LLC 0.00% of their portfolio CHICAGO, IL 100100 $0 $0 0.00% New
74 CONCOURSE FINANCIAL GROUP SECURITIES, INC. 0.00% of their portfolio BIRMINGHAM, AL 00 $0 $0 0.00% Unchanged