Vault-13

CATALYST PHARMACEUTICALS INC CPRX

COM · Common Stock · CUSIP 14888U101 · ISIN US14888U1016

394 institutional holders +12 vs Q1 2026
107,993,865108.0m shares reported held*
$3.4bnreported value*
96 new 116 added 120 reduced 82 sold out net bought ≈ $101.2m (+3.3m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($4.2m this quarter). Holder counts are more reliable. Implied quarter-end price ≈ $31.37. Options: 6 managers hold calls ($1.7m notional), 2 hold puts ($2.6m).

Trends to Q2 2026

Institutional holders

Managers reporting a position, each quarter

0200400Q3 22: 230Q4 22: 259Q1 23: 261Q2 23: 249Q3 23: 257Q4 23: 260Q1 24: 269Q2 24: 272Q3 24: 317Q4 24: 336Q1 25: 371Q2 25: 366Q3 25: 360Q4 25: 375Q1 26: 382Q2 26: 394394Q3 22Q3 23Q3 24Q3 25Q2 26
Numbers
QuarterHolders
Q3 2022230
Q4 2022259
Q1 2023261
Q2 2023249
Q3 2023257
Q4 2023260
Q1 2024269
Q2 2024272
Q3 2024317
Q4 2024336
Q1 2025371
Q2 2025366
Q3 2025360
Q4 2025375
Q1 2026382
Q2 2026394

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
4000400Q3 24: 159 bought or addedQ3 24: 128 cut or sold outQ4 24: 183 bought or addedQ4 24: 130 cut or sold outQ4 24Q1 25: 191 bought or addedQ1 25: 157 cut or sold outQ2 25: 201 bought or addedQ2 25: 172 cut or sold outQ2 25Q3 25: 176 bought or addedQ3 25: 181 cut or sold outQ4 25: 175 bought or addedQ4 25: 171 cut or sold outQ4 25Q1 26: 193 bought or addedQ1 26: 160 cut or sold outQ2 26: 212 bought or addedQ2 26: 202 cut or sold outQ2 26
Numbers
QuarterBought or addedCut or sold out
Q3 2024159128
Q4 2024183130
Q1 2025191157
Q2 2025201172
Q3 2025176181
Q4 2025175171
Q1 2026193160
Q2 2026212202

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$2.5m$5m$7.5m$10mQ3 25 calls: $4.0mQ3 25 puts: $8.8mQ3 25P/C 2.21Q4 25 calls: $2.0mQ4 25 puts: $1.1mQ4 25P/C 0.52Q1 26 calls: $3.4mQ1 26 puts: $4.9mQ1 26P/C 1.44Q2 26 calls: $1.7mQ2 26 puts: $2.6mQ2 26P/C 1.57
Numbers
QuarterCallsPutsP/C
Q3 2025$4.0m$8.8m2.21
Q4 2025$2.0m$1.1m0.52
Q1 2026$3.4m$4.9m1.44
Q2 2026$1.7m$2.6m1.57

Biggest buyers

GLAZER CAPITAL, LLC New +3,602,865+3.6m
HBK INVESTMENTS L P New +2,820,302+2.8m
JPMORGAN CHASE & CO Added +2,703,082+2.7m
Qube Research & Technologies Ltd Added +1,841,689+1.8m
NEXPOINT ASSET MANAGEMENT, L.P. New +1,602,557+1.6m
AMERICAN CENTURY COMPANIES INC Added +1,415,505+1.4m
Polar Asset Management Partners Inc. New +1,150,300+1.2m
WATER ISLAND CAPITAL LLC New +933,819+933.8k
HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND New +795,700+795.7k
STATE STREET CORP Added +763,976+764.0k

Biggest sellers

DEERFIELD MANAGEMENT COMPANY, L.P. Sold out -3,943,600-3.9m
ROYCE & ASSOCIATES LP Reduced -1,731,264-1.7m
BANK OF AMERICA CORP /DE/ Reduced -1,725,180-1.7m
Fundsmith LLP Sold out -844,887-844.9k
SUSQUEHANNA INTERNATIONAL GROUP, LLP Reduced -811,243-811.2k
NOMURA ASSET MANAGEMENT INTERNATIONAL INC. Sold out -748,104-748.1k
FEDERATED HERMES, INC. Sold out -740,297-740.3k
VICTORY CAPITAL MANAGEMENT INC Reduced -734,552-734.6k
PRICE T ROWE ASSOCIATES INC /MD/ Reduced -614,832-614.8k
RAYMOND JAMES FINANCIAL INC Reduced -593,160-593.2k

Biggest calls

Schonfeld Strategic Advisors LLC New $785.8k25.0k shares
CITADEL ADVISORS LLC Reduced $361.4k11.5k shares
JANE STREET GROUP, LLC Reduced $282.9k9.0k shares
SUMMIT SECURITIES GROUP LLC New $172.9k5.5k shares
GROUP ONE TRADING LLC Reduced $47.1k1.5k shares
SIMPLEX TRADING, LLC Reduced $15.5k2.3k shares

Biggest puts

SUSQUEHANNA INTERNATIONAL GROUP, LLP Added $2.6m83.0k shares
SIMPLEX TRADING, LLC Reduced $0200 shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
BlackRock, Inc. 13G · institution filed 2025-04-28 13.9% 16.9m≈ $530.9m 2025-04-28
STATE STREET CORP 13G · institution new · filed 2025-11-10 5.2% new 6.4m≈ $201.3m 2025-11-10

Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-26)

Holders, Q2 2026

#ManagerLocationShares Value% of their portfolioChangeShares change
1 BlackRock, Inc. 0.01% of their portfolio New York, NY 19,158,78519.2m $602.2m $602.2m 0.01% Added +384.3k +384,255
2 STATE STREET CORP 0.01% of their portfolio BOSTON, MA 7,627,0367.6m $239.7m $239.7m 0.01% Added +764.0k +763,976
3 AMERICAN CENTURY COMPANIES INC 0.08% of their portfolio KANSAS CITY, MO 5,553,9215.6m $174.6m $174.6m 0.08% Added +1.4m +1,415,505
4 VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio MALVERN, PA 5,135,3455.1m $161.4m $161.4m 0.00% Added +12.7k +12,679
5 DIMENSIONAL FUND ADVISORS LP 0.02% of their portfolio AUSTIN, TX 3,634,1713.6m $114.2m $114.2m 0.02% Added +204.6k +204,556
6 GLAZER CAPITAL, LLC 2.79% of their portfolio New York, NY 3,602,8653.6m $113.2m $113.2m 2.79% New
7 JPMORGAN CHASE & CO 0.01% of their portfolio NEW YORK, NY 3,169,9023.2m $99.9m $99.9m 0.01% Added +2.7m +2,703,082
8 GEODE CAPITAL MANAGEMENT, LLC 0.01% of their portfolio BOSTON, MA 3,150,2563.2m $99.0m $99.0m 0.01% Added +177.9k +177,854
9 HBK INVESTMENTS L P 1.04% of their portfolio DALLAS, TX 2,820,3022.8m $88.6m $88.6m 1.04% New
10 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 2,760,3582.8m $86.8m $86.8m 0.00% Added +73.1k +73,059
11 VANGUARD PORTFOLIO MANAGEMENT LLC 0.00% of their portfolio MALVERN, PA 2,428,9222.4m $76.3m $76.3m 0.00% Reduced -46.5k -46,545
12 Jupiter Topco LLC 0.03% of their portfolio NEW YORK, NY 2,277,8222.3m $71.6m $71.6m 0.03% First filing
13 Qube Research & Technologies Ltd 0.08% of their portfolio LONDON, X0 2,254,3552.3m $70.9m $70.9m 0.08% Added +1.8m +1,841,689
14 RENAISSANCE TECHNOLOGIES LLC 0.09% of their portfolio NEW YORK, NY 2,136,0772.1m $67.1m $67.1m 0.09% Reduced -211.4k -211,400
15 Boston Partners 0.05% of their portfolio BOSTON, MA 1,658,9361.7m $52.2m $52.2m 0.05% Reduced -52.6k -52,637
16 NEXPOINT ASSET MANAGEMENT, L.P. 3.37% of their portfolio Dallas, TX 1,602,5571.6m $50.4m $50.4m 3.37% New
17 UBS Group AG 0.01% of their portfolio ZURICH, V8 1,453,7261.5m $45.7m $45.7m 0.01% Added +467.6k +467,636
18 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 1,330,5201.3m $41.8m $41.8m 0.00% Added +92.8k +92,768
19 BANK OF AMERICA CORP /DE/ 0.00% of their portfolio CHARLOTTE, NC 1,311,3661.3m $41.2m $41.2m 0.00% Reduced -1.7m -1,725,180
20 GOLDMAN SACHS GROUP INC 0.00% of their portfolio NEW YORK, NY 1,194,2001.2m $37.5m $37.5m 0.00% Added +209.5k +209,466
21 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio SAN FRANCISCO, CA 1,159,4561.2m $36.4m $36.4m 0.00% Reduced -270.4k -270,386
22 Polar Asset Management Partners Inc. 0.66% of their portfolio TORONTO, A6 1,150,3001.2m $36.2m $36.2m 0.66% New
23 MILLENNIUM MANAGEMENT LLC 0.02% of their portfolio NEW YORK, NY 1,068,7241.1m $33.6m $33.6m 0.02% Added +301.7k +301,733
24 WATER ISLAND CAPITAL LLC 3.11% of their portfolio NEW YORK, NY 933,819933.8k $29.3m $29.3m 3.11% New
25 MARSHALL WACE, LLP 0.02% of their portfolio LONDON, X0 911,700911.7k $28.7m $28.7m 0.02% Added +709.9k +709,885
26 KENNEDY CAPITAL MANAGEMENT LLC 0.48% of their portfolio ST LOUIS, MO 856,609856.6k $26.9m $26.9m 0.48% Reduced -343.0k -342,989
27 VANGUARD FIDUCIARY TRUST CO 0.01% of their portfolio MALVERN, PA 830,669830.7k $26.1m $26.1m 0.01% Added +28.0k +28,038
28 HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND 0.04% of their portfolio TORONTO, A6 795,700795.7k $25.0m $25.0m 0.04% New
29 Swedbank AB 0.02% of their portfolio STOCKHOLM, V7 775,032775.0k $24.4m $24.4m 0.02% Added +158.9k +158,900
30 ARROWSTREET CAPITAL, LIMITED PARTNERSHIP 0.01% of their portfolio BOSTON, MA 748,924748.9k $23.5m $23.5m 0.01% Reduced -206.4k -206,391
31 Bank of New York Mellon Corp 0.00% of their portfolio NEW YORK, NY 703,228703.2k $22.1m $22.1m 0.00% Added +20.9k +20,939
32 PRINCIPAL FINANCIAL GROUP INC 0.01% of their portfolio DES MOINES, IA 683,270683.3k $21.5m $21.5m 0.01% Added +7.3k +7,289
33 AQR Arbitrage LLC 0.30% of their portfolio Greenwich, CT 674,223674.2k $21.2m $21.2m 0.30% New
34 SYSTEMATIC FINANCIAL MANAGEMENT LP 0.42% of their portfolio TEANECK, NJ 667,883667.9k $21.0m $21.0m 0.42% Reduced -79.6k -79,632
35 FIL Ltd 0.01% of their portfolio HAMILTON, D0 650,000650.0k $20.4m $20.4m 0.01% New
36 Sagefield Capital LP 1.33% of their portfolio DALLAS, TX 569,481569.5k $17.9m $17.9m 1.33% New
37 GLENMEDE TRUST CO NA 0.07% of their portfolio PHILADELPHIA, PA 501,212501.2k $15.8m $15.8m 0.07% Reduced -64.2k -64,212
38 Invesco Ltd. 0.00% of their portfolio ATLANTA, GA 445,990446.0k $14.0m $14.0m 0.00% Reduced -306.8k -306,849
39 Nuveen, LLC 0.00% of their portfolio CHARLOTTE, NC 437,351437.4k $13.7m $13.7m 0.00% Added +17.8k +17,843
40 GABLES CAPITAL MANAGEMENT INC. 4.76% of their portfolio MIAMI, FL 419,181419.2k $13.2m $13.2m 4.76% Reduced -5.4k -5,400
41 First Trust Capital Management L.P. 0.76% of their portfolio CHICAGO, IL 416,209416.2k $13.1m $13.1m 0.76% New
42 Public Sector Pension Investment Board 0.03% of their portfolio MONTREAL, A8 395,192395.2k $12.4m $12.4m 0.03% Reduced -131.2k -131,157
43 JW Asset Management, LLC 3.82% of their portfolio MIAMI BEACH, FL 388,392388.4k $12.2m $12.2m 3.82% Unchanged
44 Allianz Asset Management GmbH 0.01% of their portfolio MUNICH, 2M 372,989373.0k $9.2m $9.2m 0.01% Unchanged
45 WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC 0.04% of their portfolio CHICAGO, IL 371,530371.5k $11.7m $11.7m 0.04% Reduced -107.5k -107,511
46 FMR LLC 0.00% of their portfolio BOSTON, MA 360,468360.5k $11.3m $11.3m 0.00% Added +83.7k +83,690
47 ROYCE & ASSOCIATES LP 0.09% of their portfolio New York, NY 358,642358.6k $11.3m $11.3m 0.09% Reduced -1.7m -1,731,264
48 SOROS FUND MANAGEMENT LLC 0.14% of their portfolio NEW YORK, NY 344,593344.6k $10.8m $10.8m 0.14% New
49 LSV ASSET MANAGEMENT 0.02% of their portfolio CHICAGO, IL 325,200325.2k $10.2m $10.2m 0.02% Reduced -284.3k -284,300
50 RAYMOND JAMES FINANCIAL INC 0.00% of their portfolio ST. PETERSBURG, FL 296,780296.8k $9.3m $9.3m 0.00% Reduced -593.2k -593,160
51 OBERWEIS ASSET MANAGEMENT INC/ 0.19% of their portfolio LISLE, IL 293,670293.7k $9.2m $9.2m 0.19% Reduced -486.9k -486,900
52 WINTON GROUP Ltd 0.29% of their portfolio LONDON, X0 287,736287.7k $9.0m $9.0m 0.29% Added +220.0k +220,016
53 UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio NEW YORK, NY 284,154284.2k $8.9m $8.9m 0.00% Added +3.3k +3,265
54 FIRST TRUST ADVISORS LP 0.01% of their portfolio Wheaton, IL 282,887282.9k $8.9m $8.9m 0.01% Reduced -63.4k -63,357
55 Legal & General Group Plc 0.00% of their portfolio London, X0 275,513275.5k $8.7m $8.7m 0.00% Added +5.6k +5,646
56 PICTON MAHONEY ASSET MANAGEMENT 0.08% of their portfolio Toronto, A6 275,000275.0k $8.6m $8.6m 0.08% Added +274.9k +274,945
57 RHUMBLINE ADVISERS 0.01% of their portfolio BOSTON, MA 272,465272.5k $8.6m $8.6m 0.01% Reduced -33.1k -33,055
58 GABELLI FUNDS LLC 0.05% of their portfolio Rye, NY 267,750267.8k $8.4m $8.4m 0.05% New
59 Groupe la Francaise 0.10% of their portfolio PARIS, I0 256,497256.5k $8.1m $8.1m 0.10% New
60 Man Group plc 0.01% of their portfolio LONDON, X0 250,000250.0k $7.9m $7.9m 0.01% Added +164.2k +164,162
61 Melqart Asset Management (UK) Ltd 0.74% of their portfolio London, X0 247,556247.6k $7.8m $7.8m 0.74% New
62 AMERIPRISE FINANCIAL INC 0.00% of their portfolio MINNEAPOLIS, MN 238,981239.0k $7.5m $7.5m 0.00% Reduced -10.3k -10,324
63 Swiss National Bank 0.00% of their portfolio ZURICH, V8 220,600220.6k $6.9m $6.9m 0.00% Reduced -8.7k -8,700
64 THIRD AVENUE MANAGEMENT LLC 1.06% of their portfolio NEW YORK, NY 210,161210.2k $6.6m $6.6m 1.06% Unchanged
65 Assenagon Asset Management S.A. 0.00% of their portfolio SENNINGERBERG, N4 206,538206.5k $6.5m $6.5m 0.00% Added +45.9k +45,923
66 CREDIT INDUSTRIEL ET COMMERCIAL 0.66% of their portfolio PARIS FRANCE, I0 193,503193.5k $6.1m $6.1m 0.66% New
67 Creative Planning 0.00% of their portfolio OVERLAND PARK, KS 187,728187.7k $5.9m $5.9m 0.00% Added +53.5k +53,525
68 DEUTSCHE BANK AG\ 0.00% of their portfolio FRANKFURT AM MAIN, 2M 186,874186.9k $5.9m $5.9m 0.00% Added +24.1k +24,116
69 DekaBank Deutsche Girozentrale 0.01% of their portfolio FRANKFURT, 2M 183,376183.4k $4.4m $4.4m 0.01% Unchanged
70 Moran Wealth Management, LLC 0.16% of their portfolio NAPLES, FL 180,915180.9k $5.7m $5.7m 0.16% Added +12.0k +11,954
71 Point72 Asset Management, L.P. 0.01% of their portfolio STAMFORD, CT 176,560176.6k $5.5m $5.5m 0.01% Reduced -249.3k -249,305
72 Linden Thomas Advisory Services, LLC 0.45% of their portfolio Charlotte, NC 176,004176.0k $5.5m $5.5m 0.45% Added +12.4k +12,413
73 GABELLI & Co INVESTMENT ADVISERS, INC. 0.73% of their portfolio Rye, NY 159,003159.0k $5.0m $5.0m 0.73% New
74 PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio BALTIMORE, MD 158,614158.6k $5.0m $5.0m 0.00% Reduced -614.8k -614,832
75 ROYAL BANK OF CANADA 0.00% of their portfolio TORONTO, A6 152,913152.9k $4.8m $4.8m 0.00% Reduced -2.3k -2,293
76 Bridge City Capital, LLC 1.10% of their portfolio LAKE OSWEGO, OR 152,684152.7k $4.8m $4.8m 1.10% Reduced -3.0k -3,005
77 HARVEST MANAGEMENT LLC 2.09% of their portfolio New York, NY 150,000150.0k $4.7m $4.7m 2.09% New
78 Athos Capital Ltd 1.69% of their portfolio HONG KONG, K3 150,000150.0k $4.7m $4.7m 1.69% New
79 ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio NASHVILLE, TN 148,550148.6k $3.7m $3.7m 0.00% Added +28.7k +28,730
80 NEW YORK STATE TEACHERS RETIREMENT SYSTEM 0.01% of their portfolio ALBANY, NY 142,295142.3k $4.5m $4.5m 0.01% Reduced -964 -964
81 CITIGROUP INC 0.00% of their portfolio NEW YORK, NY 136,669136.7k $4.3m $4.3m 0.00% Added +100.6k +100,645
82 BESSEMER GROUP INC 0.01% of their portfolio WOODBRIDGE, NJ 136,606136.6k $4.3m $4.3m 0.01% Reduced -2.3k -2,345
83 D. E. Shaw & Co., Inc. 0.00% of their portfolio New York, NY 134,531134.5k $4.2m $4.2m 0.00% Added +94.0k +93,989
84 BI Asset Management Fondsmaeglerselskab A/S 0.03% of their portfolio KOBENHAVN, G7 133,471133.5k $4.2m $4.2m 0.03% New
85 VICTORY CAPITAL MANAGEMENT INC 0.00% of their portfolio San Antonio, TX 132,072132.1k $4.2m $4.2m 0.00% Reduced -734.6k -734,552
86 WELLS FARGO & COMPANY/MN 0.00% of their portfolio SAN FRANCISCO, CA 130,234130.2k $4.1m $4.1m 0.00% Added +49.5k +49,535
87 Schonfeld Strategic Advisors LLC 0.02% of their portfolio NEW YORK, NY 127,302127.3k $4.0m $4.0m 0.02% New
88 COMMONWEALTH OF PENNSYLVANIA PUBLIC SCHOOL EMPLS RETRMT SYS 0.02% of their portfolio HARRISBURG, PA 127,280127.3k $4.0m $4.0m 0.02% Added +98.7k +98,708
89 Maven Securities LTD 0.38% of their portfolio ST HELIER, Y9 124,040124.0k $3.9m $3.9m 0.38% New
90 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio WEST SACRAMENTO, CA 123,943123.9k $3.9m $3.9m 0.00% Reduced -16.8k -16,773
91 Advisors Asset Management, Inc. 0.06% of their portfolio Monument, CO 123,743123.7k $3.9m $3.9m 0.06% Reduced -54.0k -53,960
92 ASSETMARK, INC 0.01% of their portfolio CONCORD, CA 123,492123.5k $3.9m $3.9m 0.01% Added +21.1k +21,056
93 Chicago Capital Management, LLC 2.61% of their portfolio CHICAGO, IL 122,650122.7k $2.9m $2.9m 2.61% New
94 PRUDENTIAL FINANCIAL INC 0.00% of their portfolio NEWARK, NJ 119,969120.0k $3.8m $3.8m 0.00% Reduced -22.5k -22,535
95 FRANKLIN RESOURCES INC 0.00% of their portfolio San Mateo, CA 119,516119.5k $3.8m $3.8m 0.00% Reduced -297.2k -297,178
96 Cyndeo Wealth Partners, LLC 0.18% of their portfolio ST. PETERSBURG, FL 118,444118.4k $3.7m $3.7m 0.18% Unchanged
97 ABC ARBITRAGE SA 0.40% of their portfolio PARIS, I0 117,681117.7k $3.7m $3.7m 0.40% New
98 Kintayl Capital LP 1.73% of their portfolio NEW YORK, NY 114,111114.1k $3.6m $3.6m 1.73% New
99 CLARK ESTATES INC/NY 0.83% of their portfolio NEW YORK, NY 113,918113.9k $3.6m $3.6m 0.83% Unchanged
100 Cresset Asset Management, LLC 0.01% of their portfolio Chicago, IL 108,452108.5k $3.4m $3.4m 0.01% Added +22.4k +22,389