CARIBOU BIOSCIENCES INC CRBU
COM · Common Stock · CUSIP 142038108 · ISIN US1420381089
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersBerkeley, CA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($106.2k this quarter). Holder counts are more reliable. Shares outstanding: 90.4m as of 2024-08-01, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $1.65. Options: 5 managers hold calls ($54.3k notional), 5 hold puts ($163.3k).
Trends to Q2 2024
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 114 |
| Q4 2022 | 135 |
| Q1 2023 | 128 |
| Q2 2023 | 123 |
| Q3 2023 | 128 |
| Q4 2023 | 146 |
| Q1 2024 | 152 |
| Q2 2024 | 141 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 62 | 48 |
| Q1 2023 | 62 | 52 |
| Q2 2023 | 62 | 52 |
| Q3 2023 | 84 | 39 |
| Q4 2023 | 82 | 43 |
| Q1 2024 | 69 | 67 |
| Q2 2024 | 65 | 80 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2023 | $616.0k | $363.8k | 0.59 |
| Q4 2023 | $544.5k | $318.7k | 0.59 |
| Q1 2024 | $627.6k | $554.6k | 0.88 |
| Q2 2024 | $54.3k | $163.3k | 3.01 |
Biggest buyers
| BANK OF AMERICA CORP /DE/ | Added | +3.0m |
| RENAISSANCE TECHNOLOGIES LLC | New | +1.5m |
| TWO SIGMA ADVISERS, LP | Added | +989.3k |
| TWO SIGMA INVESTMENTS, LP | Added | +889.4k |
| JANE STREET GROUP, LLC | Added | +607.3k |
| MILLENNIUM MANAGEMENT LLC | Added | +599.0k |
| GOLDMAN SACHS GROUP INC | Added | +585.9k |
| Kynam Capital Management, LP | Added | +578.2k |
| DIMENSIONAL FUND ADVISORS LP | Added | +536.2k |
| VANGUARD GROUP INC | Added | +433.9k |
Biggest sellers
| Avidity Partners Management LP | Sold out | -5.8m |
| STATE STREET CORP | Reduced | -4.7m |
| ALKEON CAPITAL MANAGEMENT LLC | Sold out | -2.7m |
| PFM Health Sciences, LP | Reduced | -2.4m |
| Paradigm Biocapital Advisors LP | Sold out | -2.2m |
| Point72 Asset Management, L.P. | Reduced | -1.2m |
| Schonfeld Strategic Advisors LLC | Reduced | -951.1k |
| MORGAN STANLEY | Reduced | -625.0k |
| Rafferty Asset Management, LLC | Sold out | -541.4k |
| Candriam S.C.A. | Reduced | -520.0k |
Biggest calls
| CITADEL ADVISORS LLC | Reduced | $29.5k18.0k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $23.8k14.5k shares |
| GROUP ONE TRADING LLC | Reduced | $984600 shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
| SIMPLEX TRADING, LLC | New | $0100 shares |
Biggest puts
| CITADEL ADVISORS LLC | Added | $115.5k70.4k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $31.8k19.4k shares |
| GROUP ONE TRADING LLC | New | $10.0k6.1k shares |
| SIMPLEX TRADING, LLC | Added | $6.0k3.7k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| BlackRock, Inc. 13G · institution +5.2 pts · filed 2026-07-27 | 7.2% |
Haurwitz Rachel E.
13D · may seek influence
new · filed 2025-04-25
Stated purposeThe Reporting Persons intend to continuously review their investment in the Issuer, and may in the future determine to (1) acquire additional securities of the Issuer, through open market purchases, private agreements, or otherwise (subject to the Issuer's Insider Trading Policy); (2) dispose of all or a portion of the securities of the Issuer owned by them (including through 10b5-1 plans) (subject to the Issuer's Insider Trading Policy); or (3) take any other available course of action. Notwithstanding anything contained herein, the Reporting Persons specifically reserve the right to change their intention with respect to any or all of such matters. Dr. Haurwitz is the President and Chief Executive Officer and serves as a member of the Board of Directors of the Issuer and acquired her se… Full filing |
5.0% |
Insider purchases and sales in Q2 2024
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q3 2022 | 0 | — | 1 | $485.2k | — |
| Q4 2022 | 0 | — | 1 | $108.0k | — |
| Q1 2023 | 0 | — | 1 | $35.5k | — |
| Q2 2023 | 0 | — | 0 | — | — |
| Q3 2023 | 0 | — | 0 | — | — |
| Q4 2023 | 0 | — | 0 | — | — |
| Q1 2024 | 0 | — | 0 | — | — |
| Q2 2024 | 0 | — | 0 | — | — |
None reported in Q2 2024.
Holders, Q2 2024
| Manager | Shares | Change |
|---|---|---|
| BlackRock Inc. 0.00% of their portfolio | 6.9m $11.4m | Reduced -57.2k |
| VANGUARD GROUP INC 0.00% of their portfolio | 4.5m $7.5m | Added +433.9k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 4.2m $6.8m | Added +3.0m |
| PFM Health Sciences, LP 0.36% of their portfolio | 4.1m $6.7m | Reduced -2.4m |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 2.6m $4.3m | Added +536.2k |
| Point72 Asset Management, L.P. 0.01% of their portfolio | 2.3m $3.8m | Reduced -1.2m |
| Elmwood Wealth Management, Inc. 1.71% of their portfolio | 2.3m $3.8m | Reduced -29.5k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 1.9m $3.1m | Added +63.5k |
| Kynam Capital Management, LP 0.28% of their portfolio | 1.6m $2.7m | Added +578.2k |
| STATE STREET CORP 0.00% of their portfolio | 1.6m $2.6m | Reduced -4.7m |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 1.5m $2.4m | New |
| FMR LLC 0.00% of their portfolio | 1.5m $2.4m | Added +26.7k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 1.2m $1.9m | Added +585.9k |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 1.1m $1.8m | Added +889.4k |
| TWO SIGMA ADVISERS, LP 0.00% of their portfolio | 1.0m $1.7m | Added +989.3k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 928.1k $1.5m | Reduced -170.1k |
| Schonfeld Strategic Advisors LLC 0.01% of their portfolio | 891.9k $1.5m | Reduced -951.1k |
| FIL Ltd 0.00% of their portfolio | 860.7k $1.4m | Unchanged |
| Rokos Capital Management LLP 0.03% of their portfolio | 840.6k $1.4m | Unchanged |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 720.5k $1.2m | Added +599.0k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 710.1k $1.2m | Reduced -24.1k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 668.5k $1.1m | Added +607.3k |
| MAVERICK CAPITAL LTD 0.02% of their portfolio | 652.5k $1.1m | Unchanged |
| Candriam S.C.A. 0.01% of their portfolio | 625.1k $1.0m | Reduced -520.0k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 621.2k $1.0m | Reduced -203.5k |
| MORGAN STANLEY 0.00% of their portfolio | 618.5k $1.0m | Reduced -625.0k |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 523.2k $858.1k | Added +81.4k |
| 72 Investment Holdings, LLC 1.95% of their portfolio | 474.1k $777.5k | Unchanged |
| Bank of New York Mellon Corp 0.00% of their portfolio | 308.3k $505.6k | Added +38.1k |
| Bruce & Co., Inc. 0.16% of their portfolio | 300.0k $492.0k | Added +100.0k |
| Nuveen Asset Management, LLC 0.00% of their portfolio | 267.7k $439.1k | Unchanged |
| Woodline Partners LP 0.00% of their portfolio | 235.4k $386.1k | Reduced -1.8k |
| Qube Research & Technologies Ltd 0.00% of their portfolio | 220.0k $360.8k | New |
| XTX Topco Ltd 0.03% of their portfolio | 208.2k $341.4k | New |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 191.6k $314.2k | First filing |
| Resonant Capital Advisors, LLC 0.02% of their portfolio | 184.2k $302.1k | Unchanged |
| Aberdeen Group plc 0.00% of their portfolio | 181.5k $297.6k | Unchanged |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 171.6k $281.4k | Added +86.9k |
| MARSHALL WACE, LLP 0.00% of their portfolio | 164.9k $270.5k | Reduced -203.3k |
| Walleye Capital LLC 0.00% of their portfolio | 162.8k $267.0k | New |
| Curi Capital, LLC 0.01% of their portfolio | 154.0k $252.5k | Added +60.7k |
| ROYCE & ASSOCIATES LP 0.00% of their portfolio | 142.9k $234.4k | Reduced -116.0k |
| MILESTONE ASSET MANAGEMENT, LLC 0.06% of their portfolio | 142.3k $233.4k | New |
| PRUDENTIAL FINANCIAL INC 0.00% of their portfolio | 135.5k $222.2k | Added +53.9k |
| DekaBank Deutsche Girozentrale 0.00% of their portfolio | 130.0k $666.0k | Unchanged |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 125.0k $205.0k | Added +16.5k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 124.9k $204.9k | Added +2.4k |
| Thrivent Financial for Lutherans 0.00% of their portfolio | 107.0k $175.0k | New |
| UBS Group AG 0.00% of their portfolio | 106.5k $174.7k | Reduced -301.7k |
| Artal Group S.A. 0.00% of their portfolio | 105.3k $172.8k | Unchanged |
| RAYMOND JAMES & ASSOCIATES 0.00% of their portfolio | 92.1k $151.0k | Reduced -9.1k |
| Nelson Capital Management, LLC 0.02% of their portfolio | 85.0k $139.4k | Unchanged |
| HSBC HOLDINGS PLC 0.00% of their portfolio | 80.9k $129.0k | Added +66.8k |
| Green Alpha Advisors, LLC 0.10% of their portfolio | 77.4k $126.9k | Reduced -6.2k |
| Brevan Howard Capital Management LP 0.01% of their portfolio | 77.1k $126.5k | Added +66.9k |
| Squarepoint Ops LLC 0.00% of their portfolio | 68.6k $112.5k | Reduced -101.3k |
| Invesco Ltd. 0.00% of their portfolio | 67.2k $110.2k | Reduced -3.1k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 63.5k $104.2k | Reduced -36.4k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 62.5k $102.5k | Reduced -464.4k |
| BARCLAYS PLC 0.00% of their portfolio | 58.4k $95.7k | Reduced -38.9k |
| COMMONWEALTH EQUITY SERVICES, LLC 0.00% of their portfolio | 56.2k $92.0k | Added +6.6k |
| CITIGROUP INC 0.00% of their portfolio | 52.6k $86.2k | Reduced -416.9k |
| Balyasny Asset Management L.P. 0.00% of their portfolio | 52.4k $86.0k | Reduced -110.3k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 48.8k $80.0k | Added +8.1k |
| Balboa Wealth Partners 0.02% of their portfolio | 47.9k $78.5k | New |
| Corebridge Financial, Inc. 0.00% of their portfolio | 44.3k $72.6k | First filing |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 42.8k $71.0k | Added +4.1k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 41.6k $68.2k | Added +6.3k |
| EXCHANGE TRADED CONCEPTS, LLC 0.00% of their portfolio | 40.5k $66.5k | Reduced -12.6k |
| Pale Fire Capital SE 0.01% of their portfolio | 39.1k $64.1k | Added +17.4k |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 39.1k $64.1k | Added +34.7k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 36.5k $59.8k | Added +5.2k |
| CORNERCAP INVESTMENT COUNSEL INC 0.01% of their portfolio | 35.3k $57.9k | Reduced -449 |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 34.3k $56.3k | Added +76 |
| ENVESTNET ASSET MANAGEMENT INC 0.00% of their portfolio | 33.1k $54.4k | New |
| Thrive Wealth Management, LLC 0.01% of their portfolio | 32.0k $52.5k | Unchanged |
| Point72 Asia (Singapore) Pte. Ltd. 0.01% of their portfolio | 31.8k $52.2k | New |
| Point72 (DIFC) Ltd 0.00% of their portfolio | 30.2k $49.5k | Added +24.0k |
| Walleye Trading LLC 0.00% of their portfolio | 30.0k $49.2k | Reduced -71 |
| Ancora Advisors LLC 0.00% of their portfolio | 30.0k $49.2k | Added +10.0k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 30.0k $49.2k | Reduced -5.7k |
| STANSBERRY ASSET MANAGEMENT, LLC 0.01% of their portfolio | 30.0k $49.1k | Reduced -34.4k |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 27.8k $45.6k | Added +751 |
| PRELUDE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 26.4k $43.3k | Added +6.8k |
| Freedom Investment Management, Inc. 0.00% of their portfolio | 25.8k $42.3k | New |
| Aigen Investment Management, LP 0.01% of their portfolio | 24.4k $40.1k | New |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 24.0k $40.0k | Added +572 |
| SG Americas Securities, LLC 0.00% of their portfolio | 23.4k $38.0k | Reduced -3.2k |
| Y-Intercept (Hong Kong) Ltd 0.00% of their portfolio | 22.0k $36.1k | Added +11.6k |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 0.00% of their portfolio | 21.3k $35.0k | New |
| Verition Fund Management LLC 0.00% of their portfolio | 19.6k $32.1k | New |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 18.3k $30.1k | New |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC 0.00% of their portfolio | 17.0k $27.8k | Reduced -91.6k |
| ProShare Advisors LLC 0.00% of their portfolio | 16.5k $27.1k | Reduced -4.4k |
| Prime Capital Investment Advisors, LLC 0.00% of their portfolio | 16.0k $26.3k | Reduced -292 |
| LMR Partners LLP 0.00% of their portfolio | 15.2k $24.9k | Unchanged |
| Erste Asset Management GmbH 0.00% of their portfolio | 13.9k $23.4k | Unchanged |
| Cetera Investment Advisers 0.00% of their portfolio | 12.9k $21.2k | New |
| PINNACLE ASSOCIATES LTD 0.00% of their portfolio | 12.9k $21.2k | Unchanged |
| Pinnacle Wealth Management Advisory Group, LLC 0.00% of their portfolio | 12.9k $21.2k | Unchanged |