AXSOME THERAPEUTICS INC AXSM
COM · Common Stock · CUSIP 05464T104 · ISIN US05464T1043
American biopharmaceutical company
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersNew York, NY
- Founded2012
- Websiteaxsome.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($4.3m this quarter). Holder counts are more reliable. Shares outstanding: 43.4m as of 2022-10-31, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $44.62. Options: 18 managers hold calls ($113.6m notional), 19 hold puts ($113.3m).
Biggest calls
| CITADEL ADVISORS LLC | — | $26.9m602.5k shares |
| Fairmount Funds Management LLC | — | $26.8m600.0k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | — | $25.3m566.7k shares |
| JANE STREET GROUP, LLC | — | $8.1m181.6k shares |
| Ghost Tree Capital, LLC | — | $6.7m150.0k shares |
| GROUP ONE TRADING LLC | — | $6.3m141.9k shares |
| Atika Capital Management LLC | — | $5.6m1.2k shares |
| SIMPLEX TRADING, LLC | — | $4.4m98.2k shares |
| CSS LLC/IL | — | $1.2m25.9k shares |
| WOLVERINE TRADING, LLC | — | $1.1m25.2k shares |
Biggest puts
| CITADEL ADVISORS LLC | — | $37.2m833.8k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | — | $24.2m542.4k shares |
| Ikarian Capital, LLC | — | $18.2m407.6k shares |
| JANE STREET GROUP, LLC | — | $7.1m158.6k shares |
| GROUP ONE TRADING LLC | — | $6.8m151.5k shares |
| BOOTHBAY FUND MANAGEMENT, LLC | — | $6.3m141.9k shares |
| SIMPLEX TRADING, LLC | — | $5.1m113.8k shares |
| Parallax Volatility Advisers, L.P. | — | $2.1m46.0k shares |
| JPMORGAN CHASE & CO | — | $1.9m41.9k shares |
| Balyasny Asset Management L.P. | — | $1.8m40.0k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| BlackRock, Inc. 13G · institution filed 2026-07-27 | 5.3% |
Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-26)
Insider purchases and sales in Q3 2022
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2020 | 0 | — | 0 | — | — |
| Q1 2021 | 0 | — | 0 | — | — |
| Q2 2021 | 0 | — | 0 | — | — |
| Q3 2021 | 0 | — | 0 | — | — |
| Q4 2021 | 4 | $345.1k | 0 | — | — |
| Q1 2022 | 0 | — | 0 | — | — |
| Q2 2022 | 0 | — | 0 | — | — |
| Q3 2022 | 0 | — | 0 | — | — |
None reported in Q3 2022.
Holders, Q3 2022
| Manager | Shares | Change |
|---|---|---|
| VANGUARD GROUP INC 0.00% of their portfolio | 3.1m $138.8m | — |
| BlackRock Inc. 0.00% of their portfolio | 2.2m $97.8m | — |
| Fairmount Funds Management LLC 15.61% of their portfolio | 1.9m $84.6m | — |
| RTW INVESTMENTS, LP 1.94% of their portfolio | 1.9m $84.0m | — |
| PFM Health Sciences, LP 2.83% of their portfolio | 1.7m $74.1m | — |
| Avidity Partners Management LP 1.49% of their portfolio | 1.5m $68.7m | — |
| ALETHEA CAPITAL MANAGEMENT, LLC 44.43% of their portfolio | 788.3k $35.2m | — |
| STATE STREET CORP 0.00% of their portfolio | 711.3k $31.7m | — |
| Nuveen Asset Management, LLC 0.01% of their portfolio | 693.5k $30.9m | — |
| Point72 Asset Management, L.P. 0.12% of their portfolio | 617.9k $27.6m | — |
| MORGAN STANLEY 0.00% of their portfolio | 599.5k $26.8m | — |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 562.6k $25.1m | — |
| CITADEL ADVISORS LLC 0.03% of their portfolio | 531.3k $23.7m | — |
| Paradigm Biocapital Advisors LP 3.27% of their portfolio | 520.1k $23.2m | — |
| GOLDMAN SACHS GROUP INC 0.01% of their portfolio | 519.3k $23.2m | — |
| Bellevue Group AG 0.32% of their portfolio | 496.5k $22.2m | — |
| IRIDIAN ASSET MANAGEMENT LLC/CT 1.78% of their portfolio | 401.1k $17.9m | — |
| MILLENNIUM MANAGEMENT LLC 0.02% of their portfolio | 351.1k $15.7m | — |
| FMR LLC 0.00% of their portfolio | 348.9k $15.6m | — |
| Ghost Tree Capital, LLC 5.47% of their portfolio | 300.0k $13.4m | — |
| NORTHERN TRUST CORP 0.00% of their portfolio | 288.0k $12.8m | — |
| Atika Capital Management LLC 1.33% of their portfolio | 264.3k $11.8m | — |
| NORGES BANK 0.00% of their portfolio | 256.4k $11.4m | — |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 226.4k $10.1m | — |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC 0.05% of their portfolio | 213.8k $9.5m | — |
| WMS Partners, LLC 1.18% of their portfolio | 194.0k $8.7m | — |
| JANE STREET GROUP, LLC 0.02% of their portfolio | 182.9k $8.2m | — |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 171.9k $7.7m | — |
| Invesco Ltd. 0.00% of their portfolio | 171.1k $7.6m | — |
| US BANCORP \DE\ 0.01% of their portfolio | 150.4k $6.7m | — |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.02% of their portfolio | 150.0k $6.7m | — |
| SEI INVESTMENTS CO 0.01% of their portfolio | 148.8k $6.6m | — |
| TWO SIGMA INVESTMENTS, LP 0.02% of their portfolio | 141.3k $6.3m | — |
| Bank of New York Mellon Corp 0.00% of their portfolio | 135.1k $6.0m | — |
| GROUP ONE TRADING LLC 0.20% of their portfolio | 133.8k $6.0m | — |
| WCM INVESTMENT MANAGEMENT, LLC 0.02% of their portfolio | 133.7k $5.9m | — |
| Squarepoint Ops LLC 0.05% of their portfolio | 132.6k $5.9m | — |
| Moody Aldrich Partners LLC 1.12% of their portfolio | 122.3k $5.5m | — |
| Qube Research & Technologies Ltd 0.03% of their portfolio | 121.8k $5.4m | — |
| PUTNAM INVESTMENTS LLC 0.01% of their portfolio | 112.6k $5.0m | — |
| Candriam S.C.A. 0.03% of their portfolio | 110.4k $4.9m | — |
| PEREGRINE CAPITAL MANAGEMENT LLC 0.15% of their portfolio | 106.8k $4.8m | — |
| Hennion & Walsh Asset Management, Inc. 0.31% of their portfolio | 106.6k $4.8m | — |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.01% of their portfolio | 87.6k $3.9m | — |
| MORGAN JESS S & CO INC 3.06% of their portfolio | 78.9k $3.5m | — |
| Cubist Systematic Strategies, LLC 0.03% of their portfolio | 75.8k $3.4m | — |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 73.8k $3.3m | — |
| ACT CAPITAL MANAGEMENT, LLC 4.50% of their portfolio | 73.0k $3.3m | — |
| TANG CAPITAL MANAGEMENT LLC 0.38% of their portfolio | 70.0k $3.1m | — |
| Swiss National Bank 0.00% of their portfolio | 69.2k $3.1m | — |
| CREDIT SUISSE AG/ 0.00% of their portfolio | 61.6k $2.7m | — |
| OLD NATIONAL BANCORP /IN/ 0.04% of their portfolio | 53.2k $2.4m | — |
| BALDWIN WEALTH PARTNERS LLC/MA 0.33% of their portfolio | 52.8k $2.4m | — |
| Informed Momentum Co LLC 0.51% of their portfolio | 52.1k $2.3m | — |
| Schonfeld Strategic Advisors LLC 0.02% of their portfolio | 49.4k $2.2m | — |
| Cannell & Co. 0.08% of their portfolio | 49.3k $2.2m | — |
| CITIGROUP INC 0.00% of their portfolio | 48.4k $2.2m | — |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 45.4k $2.0m | — |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 40.7k $1.8m | — |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 38.9k $1.7m | — |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 38.2k $1.7m | — |
| Global IMC LLC 0.45% of their portfolio | 38.2k $1.7m | — |
| SIMPLEX TRADING, LLC 0.07% of their portfolio | 38.1k $1.7m | — |
| Jump Financial, LLC 0.06% of their portfolio | 37.4k $1.7m | — |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 36.9k $1.6m | — |
| State of New Jersey Common Pension Fund D 0.01% of their portfolio | 35.0k $1.6m | — |
| DekaBank Deutsche Girozentrale 0.00% of their portfolio | 30.0k $1.3m | — |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 29.0k $1.3m | — |
| MACQUARIE GROUP LTD 0.00% of their portfolio | 27.7k $1.2m | — |
| Legal & General Group Plc 0.00% of their portfolio | 26.8k $1.2m | — |
| Tower Research Capital LLC (TRC) 0.02% of their portfolio | 26.3k $1.2m | — |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 25.0k $1.1m | — |
| Verition Fund Management LLC 0.01% of their portfolio | 21.9k $976.0k | — |
| MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC 0.01% of their portfolio | 21.8k $973.0k | — |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 21.6k $963.0k | — |
| TUDOR INVESTMENT CORP ET AL 0.02% of their portfolio | 20.6k $918.0k | — |
| CIBC Private Wealth Group LLC 0.00% of their portfolio | 19.3k $862.0k | — |
| UBS Group AG 0.00% of their portfolio | 18.3k $817.0k | — |
| HighVista Strategies LLC 0.43% of their portfolio | 16.9k $753.0k | — |
| MetLife Investment Management, LLC 0.01% of their portfolio | 16.3k $729.2k | — |
| Raymond James Financial Services Advisors, Inc. 0.00% of their portfolio | 15.9k $711.0k | — |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 15.7k $702.1k | — |
| GLENMEDE TRUST CO NA 0.00% of their portfolio | 15.6k $694.0k | — |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 15.5k $691.6k | — |
| Dana Investment Advisors, Inc. 0.04% of their portfolio | 14.9k $663.0k | — |
| WMG Financial Advisors, LLC 0.60% of their portfolio | 14.8k $663.0k | — |
| ENVESTNET ASSET MANAGEMENT INC 0.00% of their portfolio | 14.8k $660.0k | — |
| AMERICAN INTERNATIONAL GROUP, INC. 0.00% of their portfolio | 14.1k $630.0k | — |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 14.1k $630.0k | — |
| INTERNATIONAL BIOTECHNOLOGY TRUST PLC 0.20% of their portfolio | 14.0k $625.0k | — |
| WINTON GROUP Ltd 0.04% of their portfolio | 14.0k $623.0k | — |
| SG Americas Securities, LLC 0.01% of their portfolio | 13.9k $619.0k | — |
| Lion Street Advisors, LLC 0.29% of their portfolio | 13.3k $590.0k | — |
| Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio | 13.1k $587.0k | — |
| Meridian Wealth Management, LLC 0.06% of their portfolio | 13.1k $583.0k | — |
| Cutler Group LLC / CA 0.07% of their portfolio | 12.4k $551.0k | — |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 11.8k $527.9k | — |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 11.8k $526.0k | — |
| CSS LLC/IL 0.03% of their portfolio | 11.4k $509.0k | — |
| GSA CAPITAL PARTNERS LLP 0.06% of their portfolio | 10.9k $487.0k | — |