AVALYN PHARMACEUTICALS INC AVLN
COM SHS · Common Stock · CUSIP 05348Y105
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersBoston, MA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Shares outstanding: 44.3m as of 2026-06-02, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $32.92.
Biggest buyers
| FMR LLC | New | +5.8m |
| NOVO HOLDINGS A/S | New | +3.9m |
| SR One Capital Management, LP | New | +3.3m |
| PERCEPTIVE ADVISORS LLC | New | +2.7m |
| MONTANOVA CAPITAL, LLC | New | +2.5m |
| NVP ASSOCIATES, LLC | New | +2.3m |
| WELLINGTON MANAGEMENT GROUP LLP | New | +2.2m |
| PRICE T ROWE ASSOCIATES INC /MD/ | New | +1.7m |
| Catalio Capital Management, LP | New | +1.7m |
| T. Rowe Price Investment Management, Inc. | New | +1.6m |
Biggest sellers
| None |
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| FMR LLC 13G · passive investor +1.7 pts · filed 2026-08-06 | 13.2% |
| Novo Holdings A/S 13G · exempt (held before listing) new · filed 2026-08-14 | 8.8% |
SR ONE CAPITAL MANAGEMENT, LLC
13D · may seek influence
new · filed 2026-05-08
Stated purposeThe Funds acquired their respective shares for investment purposes. Depending on market conditions, its continuing evaluation of the business and prospects of the Issuer and other factors, the Funds and other Reporting Persons may dispose of or acquire additional shares of the Issuer. Except as set forth above, none of the Reporting Persons has any present plans which relate to or would result in: (a) The acquisition by any person of additional securities of the Issuer, or the disposition of securities of the Issuer; (b) An extraordinary corporate transaction, such as a merger, reorganization or liquidation, involving the Issuer or any of its subsidiaries; (c) A sale or transfer of a material amount of assets of the Issuer or any of its subsidiaries; (d) Any change in the present board… Full filing |
7.5% |
| PERCEPTIVE ADVISORS LLC 13G · passive investor new · filed 2026-05-07 | 6.0% |
SUVRETTA CAPITAL MANAGEMENT, LLC
13D · may seek influence
new · filed 2026-05-08
Stated purposeThe disclosure in Item 3 above is incorporated herein by reference. The Funds hold securities of the Issuer for investment purposes. The Reporting Persons or their affiliates may purchase additional securities or dispose of securities in varying amounts and at varying times depending upon the Reporting Persons' continuing assessments of pertinent factors, including the availability of shares of Common Stock or other securities for purchase at particular price levels, the business prospects of the Issuer, other business investment opportunities, economic conditions, stock market conditions, the attitudes and actions of the board of directors of the Issuer (the "Board") and management of the Issuer, and the availability and nature of opportunities to dispose of securities of the Issuer. … Full filing |
5.6% |
| Norwest Venture Partners XV, LP 13G · exempt (held before listing) new · filed 2026-08-11 | 5.1% |
Insider purchases and sales since 1 Apr 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2024 | 0 | — | 0 | — | — |
| Q1 2025 | 0 | — | 0 | — | — |
| Q2 2025 | 0 | — | 0 | — | — |
| Q3 2025 | 0 | — | 0 | — | — |
| Q4 2025 | 0 | — | 0 | — | — |
| Q1 2026 | 0 | — | 0 | — | — |
| Q2 2026 | 1 | $5.0m | 0 | — | — |
| Q3 2026 | 0 | — | 0 | — | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2026-05-01 | Novo Holdings A/S 10% owner | Bought | $10.0m555.6k shares |
| 2026-05-01 | George Simeon +1 10% owner · See Note 2 | Bought | $5.0m277.8k shares |
| 2026-05-01 | Carroll Jill Director · See Note 2 | Bought | $5.0m277.8k shares |
| 2026-05-01 | George Simeon +1 10% owner · See Note 4 | Bought | $5.0m277.8k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2026
| Manager | Shares | Change |
|---|---|---|
| FMR LLC 0.01% of their portfolio | 5.8m $192.1m | New |
| NOVO HOLDINGS A/S 7.42% of their portfolio | 3.9m $127.8m | New |
| SR One Capital Management, LP 10.48% of their portfolio | 3.3m $108.9m | New |
| PERCEPTIVE ADVISORS LLC 1.37% of their portfolio | 2.7m $88.1m | New |
| MONTANOVA CAPITAL, LLC 1.73% of their portfolio | 2.5m $82.4m | New |
| NVP ASSOCIATES, LLC 22.75% of their portfolio | 2.3m $74.7m | New |
| WELLINGTON MANAGEMENT GROUP LLP 0.01% of their portfolio | 2.2m $72.5m | New |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.01% of their portfolio | 1.7m $57.1m | New |
| Catalio Capital Management, LP 10.37% of their portfolio | 1.7m $55.2m | New |
| T. Rowe Price Investment Management, Inc. 0.03% of their portfolio | 1.6m $52.8m | New |
| EVENTIDE ASSET MANAGEMENT, LLC 0.61% of their portfolio | 1.4m $45.3m | New |
| Bellevue Group AG 0.94% of their portfolio | 1.4m $44.4m | New |
| BlackRock, Inc. 0.00% of their portfolio | 977.3k $32.2m | New |
| Pivotal bioVenture Partners Investment Advisor LLC 10.34% of their portfolio | 966.8k $31.8m | New |
| CITADEL ADVISORS LLC 0.02% of their portfolio | 959.1k $31.6m | New |
| ANDERA PARTNERS 14.82% of their portfolio | 929.8k $30.6m | New |
| JENNISON ASSOCIATES LLC 0.02% of their portfolio | 812.7k $26.8m | New |
| BRAIDWELL LP 0.98% of their portfolio | 801.4k $26.4m | New |
| TPG GP A, LLC 0.51% of their portfolio | 773.1k $25.4m | New |
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 739.8k $24.4m | New |
| DEERFIELD MANAGEMENT COMPANY, L.P. 0.25% of their portfolio | 731.0k $24.1m | New |
| Rock Springs Capital Management LP 1.07% of their portfolio | 662.9k $21.8m | New |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 434.6k $14.3m | New |
| Soleus Capital Management, L.P. 0.48% of their portfolio | 419.0k $13.8m | New |
| INFINITUM ASSET MANAGEMENT, LLC 1.38% of their portfolio | 411.4k $13.5m | New |
| BAKER BROS. ADVISORS LP 0.06% of their portfolio | 350.0k $11.5m | New |
| FRANKLIN RESOURCES INC 0.00% of their portfolio | 331.7k $10.9m | New |
| SILVERARC CAPITAL MANAGEMENT, LLC 1.21% of their portfolio | 330.5k $10.9m | New |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 283.9k $9.3m | New |
| FEDERATED HERMES, INC. 0.01% of their portfolio | 160.0k $5.3m | New |
| Woodline Partners LP 0.02% of their portfolio | 151.0k $5.0m | New |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 147.0k $4.8m | New |
| ADAR1 Capital Management, LLC 0.23% of their portfolio | 146.4k $4.8m | New |
| NORTHERN TRUST CORP 0.00% of their portfolio | 136.4k $4.5m | New |
| STEMPOINT CAPITAL LP 0.67% of their portfolio | 118.0k $3.9m | New |
| VANGUARD PORTFOLIO MANAGEMENT LLC 0.00% of their portfolio | 117.3k $3.9m | New |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 116.8k $3.8m | New |
| ACUTA CAPITAL PARTNERS, LLC 2.64% of their portfolio | 115.0k $3.8m | New |
| Burkehill Global Management, LP 0.14% of their portfolio | 115.0k $3.8m | New |
| MOORE CAPITAL MANAGEMENT, LP 0.08% of their portfolio | 110.5k $3.6m | New |
| Blackstone Inc. 0.01% of their portfolio | 98.0k $3.2m | Not comparable |
| TD Asset Management Inc 0.00% of their portfolio | 94.6k $3.1m | New |
| SEVEN GRAND MANAGERS, LLC 0.10% of their portfolio | 75.0k $2.5m | New |
| Ghisallo Capital Management LLC 0.05% of their portfolio | 70.0k $2.3m | New |
| Atom Investors LP 0.20% of their portfolio | 68.3k $2.2m | New |
| Aberdeen Group plc 0.00% of their portfolio | 67.2k $2.2m | New |
| Zimmer Partners, LP 0.05% of their portfolio | 62.5k $2.1m | New |
| Avidity Partners Management LP 0.32% of their portfolio | 60.0k $2.0m | New |
| LMR Partners LLP 0.01% of their portfolio | 54.3k $1.8m | New |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 50.0k $1.6m | New |
| Freestone Grove Partners LP 0.01% of their portfolio | 50.0k $1.6m | New |
| Brevan Howard Capital Management LP 0.02% of their portfolio | 43.0k $1.4m | New |
| Bank of New York Mellon Corp 0.00% of their portfolio | 40.1k $1.3m | New |
| Shay Capital LLC 0.15% of their portfolio | 40.0k $1.3m | New |
| Balyasny Asset Management L.P. 0.00% of their portfolio | 34.0k $1.1m | New |
| Nuveen, LLC 0.00% of their portfolio | 29.7k $976.7k | New |
| D. E. Shaw & Co., Inc. 0.00% of their portfolio | 23.0k $757.2k | New |
| Davidson Kempner Capital Management LP 0.01% of their portfolio | 23.0k $757.2k | Not comparable |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 20.5k $674.9k | New |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 16.9k $557.4k | New |
| MORGAN STANLEY 0.00% of their portfolio | 16.9k $556.5k | New |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 15.2k $501.3k | New |
| Hudson Bay Capital Management LP 0.00% of their portfolio | 14.2k $466.8k | New |
| Longaeva Partners L.P. 0.01% of their portfolio | 12.5k $411.5k | New |
| UBS Group AG 0.00% of their portfolio | 12.3k $404.8k | New |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 11.7k $384.1k | New |
| Invesco Ltd. 0.00% of their portfolio | 11.6k $382.1k | New |
| RAYMOND JAMES FINANCIAL INC 0.00% of their portfolio | 11.5k $378.0k | New |
| XTX Topco Ltd 0.00% of their portfolio | 10.6k $350.3k | New |
| MetLife Investment Management, LLC 0.00% of their portfolio | 10.3k $339.3k | New |
| SOROS FUND MANAGEMENT LLC 0.00% of their portfolio | 10.0k $329.2k | New |
| Virtu Financial LLC 0.01% of their portfolio | 8.8k $289.0k | New |
| CITIGROUP INC 0.00% of their portfolio | 8.0k $264.5k | New |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 7.9k $258.6k | New |
| Vanguard Global Advisers, LLC 0.00% of their portfolio | 7.5k $246.4k | New |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 7.1k $220.2k | New |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 6.7k $219.7k | New |
| SEI INVESTMENTS CO 0.00% of their portfolio | 6.6k $217.0k | New |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 6.0k $197.5k | New |
| Police & Firemen's Retirement System of New Jersey 0.00% of their portfolio | 5.1k $166.3k | New |
| BARCLAYS PLC 0.00% of their portfolio | 4.4k $144.5k | New |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 4.0k $130.3k | New |
| Legal & General Group Plc 0.00% of their portfolio | 3.5k $115.3k | New |
| STRS OHIO 0.00% of their portfolio | 3.4k $111.9k | New |
| Persistent Asset Partners Ltd 0.02% of their portfolio | 2.1k $67.9k | New |
| Ameritas Investment Partners, Inc. 0.00% of their portfolio | 1.6k $51.2k | New |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 1.4k $45.1k | New |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 1.1k $34.7k | New |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 588 $19.0k | New |
| NISA INVESTMENT ADVISORS, LLC 0.00% of their portfolio | 503 $16.6k | New |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 236 $7.8k | New |
| Sterling Capital Management LLC 0.00% of their portfolio | 149 $4.9k | New |